Click here to switch to the map view.

The map label for this gene is flbD [H]

Identifier: 116696285

GI number: 116696285

Start: 2658387

End: 2659448

Strand: Direct

Name: flbD [H]

Synonym: H16_B2349

Alternate gene names: 116696285

Gene position: 2658387-2659448 (Clockwise)

Preceding gene: 116696277

Following gene: 116696288

Centisome position: 91.28

GC content: 68.46

Gene sequence:

>1062_bases
GTGCCCGTGACCGCCAGCACATCGCGGCGCAGCAACGCCGCTCTCTCTGGGCAGCCCGCCAGCCACGCCGCCAGCACATC
CGAGCCGGCGCGCGAGCCCGCGCCGCGCCGTGCCATACCCTCGCAGGTGTCGCTGCTGTGGGAAAGCGCGTCGCCCGCCA
TGCAACGCCTGCTGGCCCAGATCGAGCGCGTGGCGCCCACCGATGTCACCATGCTTGCGGTAGGCGAAAGCGGCTCCGGC
AAGGAAGTGGTGGCGCGCGCGGTACATGAGCGCAGCGCGCGCCGCAACGGCCCCTTCATTGCGGTCAACTGCGGGGCGAT
CCAACCCACACTGATCGAGTCGGAACTGTTCGGCCACGAGAAAGGCGGCTTTACCGGCGCGATCGAGCAGAAGGCAGGCT
ACTTCGAGCAGGCCCATGGGGGCACGCTGTTTCTCGACGAAGTCACTGAAATGCCGCTCGAGATGCAGATCAAGTTGTTG
CGGGTGCTGGAAGGCCGCACCTTCCACCGCGTCGGCGGCGACACGCCCATCGCCACCGACGTGCGCATCCTGGCAGCCAC
CAACCGCGACCCGGTCGAGGCAGCGCGTGCCGGCCAGTTGCGTGAAGACCTGCTGTACCGGCTGGCCGTGTTCCCACTGC
ATATCCCGCCGCTGCGCGAGCGGCCCGACGATATCGTGCCGCTGGCACGCCACTTCCTGGCCGAGTACAACGCCATGGAG
CGCACCGACAAGGCCTTCTCGGCCGCCTCGCTGGAGCGGCTGGTGCGCTATGACTGGCCGGGCAATGTGCGCGAGCTGAA
GAACGCCGTCTACCGCGCCTTTATCCTGGCCGACAAGGTCGTGGAGATCGGCAACCCCAACCTGGCCACGCAGCCGCCGC
GGCCCACCACGGTAGACGGCGTGGTCAGCGTGCGCGTCGGCACCACGCTGGCCGACACCCAGCGCGAAATCATCATGGCC
ACGCTGGCGCGCTTTGACGGCGACAAGCGCCAGGCCGCGCGCGCGCTCGGCATCAGCCTGAAGACGCTGTACAACCGGCT
GGACGCCTACCGCTCCTTGTAA

Upstream 100 bases:

>100_bases
ATGTTTCCGCGCGGGCTCAGACACCTATGGCAAGCCCCTGCGCCAAAGGCTAGCATAGGAACTTCTCACGACAAGCCCGC
CCCCGACCGAGGCCTTCATT

Downstream 100 bases:

>100_bases
GGCAGCGGCGCGGCCAGCGCGCGCGACAGGGCCTCGATCGCCAGCGGCTTGGTCAGGTAGGCATGGAAGCCGGCCAGTTC
GCTGCGCCGCTGGTCTTCGG

Product: response regulator-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MPVTASTSRRSNAALSGQPASHAASTSEPAREPAPRRAIPSQVSLLWESASPAMQRLLAQIERVAPTDVTMLAVGESGSG
KEVVARAVHERSARRNGPFIAVNCGAIQPTLIESELFGHEKGGFTGAIEQKAGYFEQAHGGTLFLDEVTEMPLEMQIKLL
RVLEGRTFHRVGGDTPIATDVRILAATNRDPVEAARAGQLREDLLYRLAVFPLHIPPLRERPDDIVPLARHFLAEYNAME
RTDKAFSAASLERLVRYDWPGNVRELKNAVYRAFILADKVVEIGNPNLATQPPRPTTVDGVVSVRVGTTLADTQREIIMA
TLARFDGDKRQAARALGISLKTLYNRLDAYRSL

Sequences:

>Translated_353_residues
MPVTASTSRRSNAALSGQPASHAASTSEPAREPAPRRAIPSQVSLLWESASPAMQRLLAQIERVAPTDVTMLAVGESGSG
KEVVARAVHERSARRNGPFIAVNCGAIQPTLIESELFGHEKGGFTGAIEQKAGYFEQAHGGTLFLDEVTEMPLEMQIKLL
RVLEGRTFHRVGGDTPIATDVRILAATNRDPVEAARAGQLREDLLYRLAVFPLHIPPLRERPDDIVPLARHFLAEYNAME
RTDKAFSAASLERLVRYDWPGNVRELKNAVYRAFILADKVVEIGNPNLATQPPRPTTVDGVVSVRVGTTLADTQREIIMA
TLARFDGDKRQAARALGISLKTLYNRLDAYRSL
>Mature_352_residues
PVTASTSRRSNAALSGQPASHAASTSEPAREPAPRRAIPSQVSLLWESASPAMQRLLAQIERVAPTDVTMLAVGESGSGK
EVVARAVHERSARRNGPFIAVNCGAIQPTLIESELFGHEKGGFTGAIEQKAGYFEQAHGGTLFLDEVTEMPLEMQIKLLR
VLEGRTFHRVGGDTPIATDVRILAATNRDPVEAARAGQLREDLLYRLAVFPLHIPPLRERPDDIVPLARHFLAEYNAMER
TDKAFSAASLERLVRYDWPGNVRELKNAVYRAFILADKVVEIGNPNLATQPPRPTTVDGVVSVRVGTTLADTQREIIMAT
LARFDGDKRQAARALGISLKTLYNRLDAYRSL

Specific function: Activation of sigma-54-dependent flagellar gene promoters and strong negative autoregulatory effects on its own promoter. The synthesis and function of flbD in C.crescentus is controlled by an internal cell-cycle clock [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=300, Percent_Identity=45, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI87082117, Length=227, Percent_Identity=53.3039647577093, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788550, Length=326, Percent_Identity=40.7975460122699, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI1789087, Length=302, Percent_Identity=42.7152317880795, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=305, Percent_Identity=42.9508196721311, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=41.1392405063291, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788905, Length=274, Percent_Identity=44.8905109489051, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1790299, Length=323, Percent_Identity=42.1052631578947, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=40.1215805471125, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1787583, Length=305, Percent_Identity=39.0163934426229, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=37.5, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789828, Length=270, Percent_Identity=31.4814814814815, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87081858, Length=304, Percent_Identity=28.9473684210526, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 38632; Mature: 38500

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTASTSRRSNAALSGQPASHAASTSEPAREPAPRRAIPSQVSLLWESASPAMQRLLAQ
CCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
IERVAPTDVTMLAVGESGSGKEVVARAVHERSARRNGPFIAVNCGAIQPTLIESELFGHE
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCC
KGGFTGAIEQKAGYFEQAHGGTLFLDEVTEMPLEMQIKLLRVLEGRTFHRVGGDTPIATD
CCCCCCHHHHHCCHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCC
VRILAATNRDPVEAARAGQLREDLLYRLAVFPLHIPPLRERPDDIVPLARHFLAEYNAME
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RTDKAFSAASLERLVRYDWPGNVRELKNAVYRAFILADKVVEIGNPNLATQPPRPTTVDG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VVSVRVGTTLADTQREIIMATLARFDGDKRQAARALGISLKTLYNRLDAYRSL
EEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVTASTSRRSNAALSGQPASHAASTSEPAREPAPRRAIPSQVSLLWESASPAMQRLLAQ
CCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
IERVAPTDVTMLAVGESGSGKEVVARAVHERSARRNGPFIAVNCGAIQPTLIESELFGHE
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCC
KGGFTGAIEQKAGYFEQAHGGTLFLDEVTEMPLEMQIKLLRVLEGRTFHRVGGDTPIATD
CCCCCCHHHHHCCHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHCCCEEEECCCCCCCCCC
VRILAATNRDPVEAARAGQLREDLLYRLAVFPLHIPPLRERPDDIVPLARHFLAEYNAME
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RTDKAFSAASLERLVRYDWPGNVRELKNAVYRAFILADKVVEIGNPNLATQPPRPTTVDG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VVSVRVGTTLADTQREIIMATLARFDGDKRQAARALGISLKTLYNRLDAYRSL
EEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2315326; 11259647 [H]