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The map label for this gene is mlaA [H]

Identifier: 116696113

GI number: 116696113

Start: 2466713

End: 2467507

Strand: Direct

Name: mlaA [H]

Synonym: H16_B2177

Alternate gene names: 116696113

Gene position: 2466713-2467507 (Clockwise)

Preceding gene: 116696112

Following gene: 116696115

Centisome position: 84.69

GC content: 67.92

Gene sequence:

>795_bases
ATGCCTTTACGCCAGCGCGCTACATCCGTTGCCACCACCGCCATTGCCGCCGCCCTGCTCGCCGGCTGCGCCACCGGCCC
GCAAGCCAGTCCCGACGATCCGCTCGAGCCGATGAACCGCGCGGTCTTCACCGTCAACGACAAGCTCGACCAGTACGTGG
CCGTGCCGGTGGCCAAGGGCTACAAGGCGGTCACGCCGGAGCCGGTGCGCACCGCGGTCACCAATTTCTATTCGAACATC
GCGGACATCGGCAACTTTGCCAACAACCTGCTGCAGGGCAAGGGCGTTGAGGCAGCGGAGAGCTTCATGCGGGTCGCGAT
CAATTCCGTGCTGGGTATCGGCGGACTGATCGACATCGCCACGCCCGCCGGGCTGCAGAAGCATTCGCAGGATTTCGGCC
TGACGCTGGGCACGTGGGGCGTGCCGTCGGGACCCTACCTGGTGCTGCCGCTGTTCGGCCCCAGCTCATTCCGCGACGGC
GTGGGCCTGTATGTGAATTTCCAGTTCGACCCGACCACCTATGCCGAGCCGGCGGTGCGCAATTCGCTGTTCGGGATGAA
CGTGGTGGACGTGCGCACCAACCTGCTGGGCGCCACCGACCTGCTGAAGCTGGCGGCGCTGGACAAGTACGCCTTTGTGC
GCGATGCCTACCTGCAGCGGCGCCGCTACCTGCTGGGAGAGAACACGTCGCTGCCGGACTACGACGAAGACGACGACGGC
GGCACGGCCGCAGCACCCGCCGCGGAGGCGCCGGCGGGCACGCCTGCGCCCGCGCAGCCGCAGGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
CTGATGGGCCGCCCGCGCGAAGGCGCCCATCACAAACATGACAAGGCCGCCCGGTCATAATCACAAACCCGATGCGGCCG
ACCCCGACCCCCTTCGTACA

Downstream 100 bases:

>100_bases
CGCGGGGTCTTAGCCGCCGATCCCCAGCAGCACCACCTCGAAGGTAAGCGTGGCGTTCGGCGGAATCGTGCCCGGCACGC
CGCGCGCGCCGTAGGCCGTG

Product: VacJ-like lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPLRQRATSVATTAIAAALLAGCATGPQASPDDPLEPMNRAVFTVNDKLDQYVAVPVAKGYKAVTPEPVRTAVTNFYSNI
ADIGNFANNLLQGKGVEAAESFMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPLFGPSSFRDG
VGLYVNFQFDPTTYAEPAVRNSLFGMNVVDVRTNLLGATDLLKLAALDKYAFVRDAYLQRRRYLLGENTSLPDYDEDDDG
GTAAAPAAEAPAGTPAPAQPQAPR

Sequences:

>Translated_264_residues
MPLRQRATSVATTAIAAALLAGCATGPQASPDDPLEPMNRAVFTVNDKLDQYVAVPVAKGYKAVTPEPVRTAVTNFYSNI
ADIGNFANNLLQGKGVEAAESFMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPLFGPSSFRDG
VGLYVNFQFDPTTYAEPAVRNSLFGMNVVDVRTNLLGATDLLKLAALDKYAFVRDAYLQRRRYLLGENTSLPDYDEDDDG
GTAAAPAAEAPAGTPAPAQPQAPR
>Mature_263_residues
PLRQRATSVATTAIAAALLAGCATGPQASPDDPLEPMNRAVFTVNDKLDQYVAVPVAKGYKAVTPEPVRTAVTNFYSNIA
DIGNFANNLLQGKGVEAAESFMRVAINSVLGIGGLIDIATPAGLQKHSQDFGLTLGTWGVPSGPYLVLPLFGPSSFRDGV
GLYVNFQFDPTTYAEPAVRNSLFGMNVVDVRTNLLGATDLLKLAALDKYAFVRDAYLQRRRYLLGENTSLPDYDEDDDGG
TAAAPAAEAPAGTPAPAQPQAPR

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=230, Percent_Identity=32.6086956521739, Blast_Score=120, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 27874; Mature: 27743

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRQRATSVATTAIAAALLAGCATGPQASPDDPLEPMNRAVFTVNDKLDQYVAVPVAKG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEECCCCCCEEEEEHHCC
YKAVTPEPVRTAVTNFYSNIADIGNFANNLLQGKGVEAAESFMRVAINSVLGIGGLIDIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECC
TPAGLQKHSQDFGLTLGTWGVPSGPYLVLPLFGPSSFRDGVGLYVNFQFDPTTYAEPAVR
CCCCHHHCCHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHHH
NSLFGMNVVDVRTNLLGATDLLKLAALDKYAFVRDAYLQRRRYLLGENTSLPDYDEDDDG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GTAAAPAAEAPAGTPAPAQPQAPR
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLRQRATSVATTAIAAALLAGCATGPQASPDDPLEPMNRAVFTVNDKLDQYVAVPVAKG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCEEEEECCCCCCEEEEEHHCC
YKAVTPEPVRTAVTNFYSNIADIGNFANNLLQGKGVEAAESFMRVAINSVLGIGGLIDIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEECC
TPAGLQKHSQDFGLTLGTWGVPSGPYLVLPLFGPSSFRDGVGLYVNFQFDPTTYAEPAVR
CCCCHHHCCHHCCEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEEEECCCCCCCHHHH
NSLFGMNVVDVRTNLLGATDLLKLAALDKYAFVRDAYLQRRRYLLGENTSLPDYDEDDDG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GTAAAPAAEAPAGTPAPAQPQAPR
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]