Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 116696077

GI number: 116696077

Start: 2421270

End: 2422436

Strand: Direct

Name: macB [H]

Synonym: H16_B2141

Alternate gene names: 116696077

Gene position: 2421270-2422436 (Clockwise)

Preceding gene: 116696076

Following gene: 116696078

Centisome position: 83.13

GC content: 67.69

Gene sequence:

>1167_bases
GTGGCGATCCCGCTGACCTATATCGCGCGCAACCTGTGGGCCAGGCGCCTGACCACCGCGCTGACCGCGGGCGGGCTGGC
GCTGGTGGTGTTCGTCTTTGCCACCATGCTGATGCTGGACGCCGGCCTGAAGAAGACCCTGGTCACCACCGGCGAGCAGA
ACAACGTGGTGCTGATCCGCAAGGGCGCCGAGACCGAGATCCAGAGCTCGGTCAACCGCGACCAAGCCAGCATCATGGAG
ATGCACCCGGCCGTGGCCATGAGCGGCGCTGGCCGGCCGCTGGCCTCGCGCGAGGCGGTGGTGCTGATCTCGCTTACCAA
GACCAGCACCGGGCAGCCGTCCAACGTCGTGATCCGCGGCATCTCGCCGCCGGGCATGGACCTGCGCCCGCAGGTGCGGC
TGGTGACCGGACGCATGTTCCGGCCGGGCTCGTCCGAGATCATCGTCGGCAGCAGCATCGCCGGCGGCTTTGCCGGGGTG
CAGATCGGCGAGCACCTGCGCTTTGCCCAGCGCGACTGGACCGTGGTCGGCCACTTCGACGCCGGCGGCAGCGGCTTCGA
CTCCGAGATCTGGGGCGACGTGGACCAGCTGATGCAGTCGTTCCGGCGCAATGCGTATTCGTCGATGGTGGTGCGGCTGG
CGGATTCGGCGCTGTTCGACCGCTTTCGCGCCGATATCGACGTCGACCCGCGGCTGGCCGACGAGGCCAAGCGCGAGCAG
GCCTTCTACAGCGACCAGTCCAAGGCGCTGTCCAGCTTTATCAAGATCCTCGGCTTCACGCTGTCCACCATCTTTTCGGT
CGCGGCGATGATCGGCGCCATGATCACCATGTACGCCTCGGTGGCCAACCGCGTGGCGGAGATCGGCACGCTGCGCGCGC
TGGGTTTCAAGCGCGTCAACGTGCTGACCGCCTTCCTGATCGAAGCCGCGCTGCTGGGGCTGGTGGGCGGCATCGCAGGC
CTTGCGTGCGCCACGCTGATGCAGTTCGCGTCGTTCTCGACCACCAACTTCCAGACCTTCGCGGACCTCTCGTTCCGCTT
CATCCTGACCCCGGCCATCGCGCTGCAGACGCTGGCGTTCTCGATGGTGATGGGGCTGGCGGGCGGATTCCTGCCGGCGG
TGCGGGCGGCGCGAATGAATATCGTGGACGCGTTGCGGGCGCGCTGA

Upstream 100 bases:

>100_bases
GGCGGTGGGCGTCTTTGCCGGCATCGTGCCGGCGGTGCAGGCTGCGCGCGTGCGCATCGTCGAGGGCCTGCGGGCCATCG
GCTAGCGCGCGGAGGCTGAT

Downstream 100 bases:

>100_bases
GCGAGGGTTCGCTCCCCTCTCCCGCAAGCGGGAGAGGGAGCACGGCATCGGCATTCACGGCCCGGTAGTCGCTGCGCCCC
ACCCCCAACCTTTCCTTGCC

Product: ABC-type transporter, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAIPLTYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKKTLVTTGEQNNVVLIRKGAETEIQSSVNRDQASIME
MHPAVAMSGAGRPLASREAVVLISLTKTSTGQPSNVVIRGISPPGMDLRPQVRLVTGRMFRPGSSEIIVGSSIAGGFAGV
QIGEHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRNAYSSMVVRLADSALFDRFRADIDVDPRLADEAKREQ
AFYSDQSKALSSFIKILGFTLSTIFSVAAMIGAMITMYASVANRVAEIGTLRALGFKRVNVLTAFLIEAALLGLVGGIAG
LACATLMQFASFSTTNFQTFADLSFRFILTPAIALQTLAFSMVMGLAGGFLPAVRAARMNIVDALRAR

Sequences:

>Translated_388_residues
MAIPLTYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKKTLVTTGEQNNVVLIRKGAETEIQSSVNRDQASIME
MHPAVAMSGAGRPLASREAVVLISLTKTSTGQPSNVVIRGISPPGMDLRPQVRLVTGRMFRPGSSEIIVGSSIAGGFAGV
QIGEHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRNAYSSMVVRLADSALFDRFRADIDVDPRLADEAKREQ
AFYSDQSKALSSFIKILGFTLSTIFSVAAMIGAMITMYASVANRVAEIGTLRALGFKRVNVLTAFLIEAALLGLVGGIAG
LACATLMQFASFSTTNFQTFADLSFRFILTPAIALQTLAFSMVMGLAGGFLPAVRAARMNIVDALRAR
>Mature_387_residues
AIPLTYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKKTLVTTGEQNNVVLIRKGAETEIQSSVNRDQASIMEM
HPAVAMSGAGRPLASREAVVLISLTKTSTGQPSNVVIRGISPPGMDLRPQVRLVTGRMFRPGSSEIIVGSSIAGGFAGVQ
IGEHLRFAQRDWTVVGHFDAGGSGFDSEIWGDVDQLMQSFRRNAYSSMVVRLADSALFDRFRADIDVDPRLADEAKREQA
FYSDQSKALSSFIKILGFTLSTIFSVAAMIGAMITMYASVANRVAEIGTLRALGFKRVNVLTAFLIEAALLGLVGGIAGL
ACATLMQFASFSTTNFQTFADLSFRFILTPAIALQTLAFSMVMGLAGGFLPAVRAARMNIVDALRAR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=185, Percent_Identity=32.4324324324324, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41647; Mature: 41516

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPLTYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKKTLVTTGEQNNVVLIR
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEE
KGAETEIQSSVNRDQASIMEMHPAVAMSGAGRPLASREAVVLISLTKTSTGQPSNVVIRG
CCCCHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEC
ISPPGMDLRPQVRLVTGRMFRPGSSEIIVGSSIAGGFAGVQIGEHLRFAQRDWTVVGHFD
CCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
AGGSGFDSEIWGDVDQLMQSFRRNAYSSMVVRLADSALFDRFRADIDVDPRLADEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AFYSDQSKALSSFIKILGFTLSTIFSVAAMIGAMITMYASVANRVAEIGTLRALGFKRVN
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTAFLIEAALLGLVGGIAGLACATLMQFASFSTTNFQTFADLSFRFILTPAIALQTLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHH
SMVMGLAGGFLPAVRAARMNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPLTYIARNLWARRLTTALTAGGLALVVFVFATMLMLDAGLKKTLVTTGEQNNVVLIR
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHEECCCCCCEEEEE
KGAETEIQSSVNRDQASIMEMHPAVAMSGAGRPLASREAVVLISLTKTSTGQPSNVVIRG
CCCCHHHHHHCCHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEC
ISPPGMDLRPQVRLVTGRMFRPGSSEIIVGSSIAGGFAGVQIGEHLRFAQRDWTVVGHFD
CCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEC
AGGSGFDSEIWGDVDQLMQSFRRNAYSSMVVRLADSALFDRFRADIDVDPRLADEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AFYSDQSKALSSFIKILGFTLSTIFSVAAMIGAMITMYASVANRVAEIGTLRALGFKRVN
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTAFLIEAALLGLVGGIAGLACATLMQFASFSTTNFQTFADLSFRFILTPAIALQTLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHH
SMVMGLAGGFLPAVRAARMNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA