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The map label for this gene is gltS [H]

Identifier: 116696078

GI number: 116696078

Start: 2422676

End: 2423866

Strand: Direct

Name: gltS [H]

Synonym: H16_B2142

Alternate gene names: 116696078

Gene position: 2422676-2423866 (Clockwise)

Preceding gene: 116696077

Following gene: 116696079

Centisome position: 83.18

GC content: 66.67

Gene sequence:

>1191_bases
ATGAACCTCGACCTGCTGGGCTCGCTGCTGACTGCCGTCGTGGTGCTGCTGATCGGCACGCTGGTCAACCGCAGCGTCGG
CGTGCTGTCGCGCTACAACATTCCCGACCCTGTCACCGGCGGCCTGCTGTTCGCGATCATCGCCTCGGTGGCGCTGGCGG
CAGCGAACTTCCGCGTGGTGATCGATCCCGGCATGAAGCCGGTGCTGCTGCTGATGTTCTTCGGCGGCGTCGGGCTCTGC
GCCGACCTGCGCATGCTCAGGCGCGGCGGCAAGGCGCTGGTGATCTTCCTCATCATCCTGCTGCCCTACATCCTGGTGCA
GAACGTGGTGGGCGTGGCCATGGCCAGGACGCTGGACCTGCATCCCATCTTCGGGCTGGTGAGCGGCTCGATCACGCTGG
TGGGCGGCCACGGCACCGGCGCCGCCTATGCCGAGCGCTTTGCCGAGGTCAACAACCTGCAGGCGGTGATGGACCTGTCG
ATGACAGTGGCCACCATCGGCCTGATTGTGGGCGGCATCATCGGCGGCCCGGTGGCGCAGTACCTGATCTCGCGCTACAA
GCTGCGCTCGACCGCGCGCGAGGCCGGCGACACCGAGGAAGAAGCCGCCGCGGTTTCCCCCATCACCACCGTGGGCGCGC
TGGCCTCGCTGGCCGGCATCCTGGCCGCGGTGATCGGCGGGCGCTGGATCGCCGCGCAGATGCCCACCGGCGCCATCACC
ATCCCCGGCTTCCTGTGGTGCATGATGCTCGGCATCGCCATCCGCAACCTGCTGCCCTTTGCCGGCGTGCGCTTTGACGA
CCGCGCCACCGACCTGATCACCAATATCTGCCTGTCGCTGTTCCTGGTGATGACCATGATGGCGCTGGACCTGGCCGAGG
TGGCGCTGTCCGCCGGCCCCTTCCTGCTGATCATCGCCATGCAGGTGGTCTTCATCATCCTGTATGTGGTGCTGGTGTGC
TTCCGCTTCATGGGGGGTGACTACGAGGCTGCGGTCACCTCGGCCGCCTTTATCGGCTTCAACATGGGGTCGACCGCCAC
CGCCATGGCCAATATGCGCGCCATCACGTCCCGCTACGGGCCGGCACCCACCAGCTATTTGATCACGCCGCTGGCCGGCG
CGTTCTTCGTCGACCTGATGAACGCCTTCGTGCTGACCATGCTGCTGGCGTTGCCGCTGATCGGAGGCTGA

Upstream 100 bases:

>100_bases
CTCCCCGTCAGGCATTGCCGGCGGCCAGTGCACCCCCGGCACGGCCAGCGGCGCCCGATGGCAAGGTACCCCCGCAACCC
TCTCCGCCAGGACGCCCCCG

Downstream 100 bases:

>100_bases
CATGCGCCGCGCCCTCTTCACCCTCCTCATTGCCTTGGTGGCCAGCGCCTGGCTGGCAGGCTGCGGCGGCGGCCCGCCCG
CCGACGGCATCCGCGCCGGC

Product: Sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNLDLLGSLLTAVVVLLIGTLVNRSVGVLSRYNIPDPVTGGLLFAIIASVALAAANFRVVIDPGMKPVLLLMFFGGVGLC
ADLRMLRRGGKALVIFLIILLPYILVQNVVGVAMARTLDLHPIFGLVSGSITLVGGHGTGAAYAERFAEVNNLQAVMDLS
MTVATIGLIVGGIIGGPVAQYLISRYKLRSTAREAGDTEEEAAAVSPITTVGALASLAGILAAVIGGRWIAAQMPTGAIT
IPGFLWCMMLGIAIRNLLPFAGVRFDDRATDLITNICLSLFLVMTMMALDLAEVALSAGPFLLIIAMQVVFIILYVVLVC
FRFMGGDYEAAVTSAAFIGFNMGSTATAMANMRAITSRYGPAPTSYLITPLAGAFFVDLMNAFVLTMLLALPLIGG

Sequences:

>Translated_396_residues
MNLDLLGSLLTAVVVLLIGTLVNRSVGVLSRYNIPDPVTGGLLFAIIASVALAAANFRVVIDPGMKPVLLLMFFGGVGLC
ADLRMLRRGGKALVIFLIILLPYILVQNVVGVAMARTLDLHPIFGLVSGSITLVGGHGTGAAYAERFAEVNNLQAVMDLS
MTVATIGLIVGGIIGGPVAQYLISRYKLRSTAREAGDTEEEAAAVSPITTVGALASLAGILAAVIGGRWIAAQMPTGAIT
IPGFLWCMMLGIAIRNLLPFAGVRFDDRATDLITNICLSLFLVMTMMALDLAEVALSAGPFLLIIAMQVVFIILYVVLVC
FRFMGGDYEAAVTSAAFIGFNMGSTATAMANMRAITSRYGPAPTSYLITPLAGAFFVDLMNAFVLTMLLALPLIGG
>Mature_396_residues
MNLDLLGSLLTAVVVLLIGTLVNRSVGVLSRYNIPDPVTGGLLFAIIASVALAAANFRVVIDPGMKPVLLLMFFGGVGLC
ADLRMLRRGGKALVIFLIILLPYILVQNVVGVAMARTLDLHPIFGLVSGSITLVGGHGTGAAYAERFAEVNNLQAVMDLS
MTVATIGLIVGGIIGGPVAQYLISRYKLRSTAREAGDTEEEAAAVSPITTVGALASLAGILAAVIGGRWIAAQMPTGAIT
IPGFLWCMMLGIAIRNLLPFAGVRFDDRATDLITNICLSLFLVMTMMALDLAEVALSAGPFLLIIAMQVVFIILYVVLVC
FRFMGGDYEAAVTSAAFIGFNMGSTATAMANMRAITSRYGPAPTSYLITPLAGAFFVDLMNAFVLTMLLALPLIGG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=380, Percent_Identity=39.4736842105263, Blast_Score=230, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 41523; Mature: 41523

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDLLGSLLTAVVVLLIGTLVNRSVGVLSRYNIPDPVTGGLLFAIIASVALAAANFRVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
IDPGMKPVLLLMFFGGVGLCADLRMLRRGGKALVIFLIILLPYILVQNVVGVAMARTLDL
ECCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPIFGLVSGSITLVGGHGTGAAYAERFAEVNNLQAVMDLSMTVATIGLIVGGIIGGPVAQ
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLISRYKLRSTAREAGDTEEEAAAVSPITTVGALASLAGILAAVIGGRWIAAQMPTGAIT
HHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEE
IPGFLWCMMLGIAIRNLLPFAGVRFDDRATDLITNICLSLFLVMTMMALDLAEVALSAGP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FLLIIAMQVVFIILYVVLVCFRFMGGDYEAAVTSAAFIGFNMGSTATAMANMRAITSRYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
PAPTSYLITPLAGAFFVDLMNAFVLTMLLALPLIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLDLLGSLLTAVVVLLIGTLVNRSVGVLSRYNIPDPVTGGLLFAIIASVALAAANFRVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEE
IDPGMKPVLLLMFFGGVGLCADLRMLRRGGKALVIFLIILLPYILVQNVVGVAMARTLDL
ECCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HPIFGLVSGSITLVGGHGTGAAYAERFAEVNNLQAVMDLSMTVATIGLIVGGIIGGPVAQ
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLISRYKLRSTAREAGDTEEEAAAVSPITTVGALASLAGILAAVIGGRWIAAQMPTGAIT
HHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEE
IPGFLWCMMLGIAIRNLLPFAGVRFDDRATDLITNICLSLFLVMTMMALDLAEVALSAGP
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FLLIIAMQVVFIILYVVLVCFRFMGGDYEAAVTSAAFIGFNMGSTATAMANMRAITSRYG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
PAPTSYLITPLAGAFFVDLMNAFVLTMLLALPLIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]