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The map label for this gene is livM3 [H]

Identifier: 116695946

GI number: 116695946

Start: 2267930

End: 2269141

Strand: Direct

Name: livM3 [H]

Synonym: H16_B2010

Alternate gene names: 116695946

Gene position: 2267930-2269141 (Clockwise)

Preceding gene: 116695945

Following gene: 116695947

Centisome position: 77.87

GC content: 67.0

Gene sequence:

>1212_bases
GTGAACGTGTCTGACAACGTCTCGAAGCCGCTGCCGGCGGCCTCCGCCGCCACGGCCGAGGGCCCGCAGCGGCGCCCGGC
CATGGTGCTGGCCATCTCGGCCATCGCCCTGGTGGCCTATCTCTACTTCTTCCTGCATGCGGAATCGCAACTGGCGGTAG
CCGTGCTGCTGGCGCTGGCCGGGGCCGCGGTGTTCGCGGCGGGCCGGCTGGGCCTGACGCAGGCCGTGGAGCAGGCAGCA
TCGCGGCGGCCAGGGCAGTCCAGGCTATGGACGCTGGCCGGCACGCTGGCGCTGGTCGCGCTGTTCCACGAGAGCCATTT
CGTCCTGCTGATGCTGTGTGCCGTGCTGCTTTACACCACCGCCTGCCTGGGGCTGACAGTCCAGTTCGGGTTTTCCGGCG
TGTCCAATTTCGCGGGCGCGGCGTTCTTTGGCATCGGCGCCTACACCACGGCCGTGCTGGCCACGCACACGGGCATTCCT
CACGTGCTGGTGATCGTGCTGTCTGGCCTGGCAGCGGCCGTGATCGGCTCGGTGCTGGTTGCGCCCGTGCTGCGCACGCG
CGGCCACTATGCGGCGCTGGTGACCATCGCGTTCGGCATCCTGTTCAAGACCTTCCTTGAGGTCAACGACGTGCTGGGCG
GGCCGCAGGGCCTGCAGGTGCCCGGGATGACGCTGTTCGGCTTCGCGTTCAATGAGAGCGTGACACTGTTCGGCGTGGAC
GTGTCGTTCTACGCCAGCTATGCGCTGCTGAGCCTGCTGATCTGTGCGGGCACGTTTGCCGTGGTCAAGGCGCTGGAGCG
CTCGTGGGTAGGCCTGGCGATGGACGTGGTGCGCACCGACGAGACCGCCGCCGCCGCGTTCGGCCTGCACATCGCCCGGT
GGAAGGTGATTGCGTTCATGCTCGGCAACTTCTTTGCCGGCATCGCCGGCAGTGTCTACGGCATGGTCACTGCGTTCGTG
GCGCCCAACAACTTCACCTTCGCCGACTCGCTGCTGATGCTGTCGATCGTGATCCTGGGCGGCCTCGGCAACGTGGTGGG
CCTGGTGCCGGCGGCCATTATCGTGCTGGTGCTGCCCGAAAAGCTGCAGTTCATCCAGGAATACCGCTTCCTGTTCTACG
CGGCGCTGGTGATCGCCATCCTGCTGTTCCGCCCGGACGGCCTGATGCCGCGCAAGACCCGCCTGTTCTTTCCCCGGGAG
GATGCGCAATGA

Upstream 100 bases:

>100_bases
GTGCCCGACATCCCGAGCGCCTACAAGGACGTATTCGCCTTTGCCGTGGTCATCGTGCTGATGGCCTGGAAGCCGACCGG
ACTCATCGCGGAGAAAGCCA

Downstream 100 bases:

>100_bases
GCGACGCAATGATCCAGGTGCGCGACCTGACCATGCGCTTTGGCGGCCTGACCGCGCTGGACAACCTCCAGCTCGAGATC
CGCCGTGGCGAGATCCTGGG

Product: ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNVSDNVSKPLPAASAATAEGPQRRPAMVLAISAIALVAYLYFFLHAESQLAVAVLLALAGAAVFAAGRLGLTQAVEQAA
SRRPGQSRLWTLAGTLALVALFHESHFVLLMLCAVLLYTTACLGLTVQFGFSGVSNFAGAAFFGIGAYTTAVLATHTGIP
HVLVIVLSGLAAAVIGSVLVAPVLRTRGHYAALVTIAFGILFKTFLEVNDVLGGPQGLQVPGMTLFGFAFNESVTLFGVD
VSFYASYALLSLLICAGTFAVVKALERSWVGLAMDVVRTDETAAAAFGLHIARWKVIAFMLGNFFAGIAGSVYGMVTAFV
APNNFTFADSLLMLSIVILGGLGNVVGLVPAAIIVLVLPEKLQFIQEYRFLFYAALVIAILLFRPDGLMPRKTRLFFPRE
DAQ

Sequences:

>Translated_403_residues
MNVSDNVSKPLPAASAATAEGPQRRPAMVLAISAIALVAYLYFFLHAESQLAVAVLLALAGAAVFAAGRLGLTQAVEQAA
SRRPGQSRLWTLAGTLALVALFHESHFVLLMLCAVLLYTTACLGLTVQFGFSGVSNFAGAAFFGIGAYTTAVLATHTGIP
HVLVIVLSGLAAAVIGSVLVAPVLRTRGHYAALVTIAFGILFKTFLEVNDVLGGPQGLQVPGMTLFGFAFNESVTLFGVD
VSFYASYALLSLLICAGTFAVVKALERSWVGLAMDVVRTDETAAAAFGLHIARWKVIAFMLGNFFAGIAGSVYGMVTAFV
APNNFTFADSLLMLSIVILGGLGNVVGLVPAAIIVLVLPEKLQFIQEYRFLFYAALVIAILLFRPDGLMPRKTRLFFPRE
DAQ
>Mature_403_residues
MNVSDNVSKPLPAASAATAEGPQRRPAMVLAISAIALVAYLYFFLHAESQLAVAVLLALAGAAVFAAGRLGLTQAVEQAA
SRRPGQSRLWTLAGTLALVALFHESHFVLLMLCAVLLYTTACLGLTVQFGFSGVSNFAGAAFFGIGAYTTAVLATHTGIP
HVLVIVLSGLAAAVIGSVLVAPVLRTRGHYAALVTIAFGILFKTFLEVNDVLGGPQGLQVPGMTLFGFAFNESVTLFGVD
VSFYASYALLSLLICAGTFAVVKALERSWVGLAMDVVRTDETAAAAFGLHIARWKVIAFMLGNFFAGIAGSVYGMVTAFV
APNNFTFADSLLMLSIVILGGLGNVVGLVPAAIIVLVLPEKLQFIQEYRFLFYAALVIAILLFRPDGLMPRKTRLFFPRE
DAQ

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=289, Percent_Identity=35.2941176470588, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 42571; Mature: 42571

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]