| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is livG3 [H]
Identifier: 116695947
GI number: 116695947
Start: 2269138
End: 2269920
Strand: Direct
Name: livG3 [H]
Synonym: H16_B2011
Alternate gene names: 116695947
Gene position: 2269138-2269920 (Clockwise)
Preceding gene: 116695946
Following gene: 116695948
Centisome position: 77.91
GC content: 63.6
Gene sequence:
>783_bases ATGAGCGACGCAATGATCCAGGTGCGCGACCTGACCATGCGCTTTGGCGGCCTGACCGCGCTGGACAACCTCCAGCTCGA GATCCGCCGTGGCGAGATCCTGGGCCTGCTGGGCCCCAACGGCTCCGGCAAGACCACGTTCTTCAACGTGCTGACGGGGC TGTACAAGGCAAGCGCCGGAACCATTACCTATGACGGCAACAACGTCATCGGCAAGACGCCACAGCAGATCTACCGCAGC GGCGTGGCGCGGACGTTCCAGCGTTCGCGCTTGTCGCTGCCGCTGACGGTGTTCGACAACATCGTGATCGGCGATTACCA GAACATGCGTCACGGGCTGGTCTTCAACCTGTTCCGGCGCAAGGCGTTCCGCGCCGAGTACGAACGCTACGTGGAGTCGG TGCGCGAGCTGCTGGGCATCTTCAGCCCGCCACTGGTGGCGCGGCTGTTCGAGCCGGTGGAAACGTTCACGATGATCGAC CGCCGCCGCATCGAGGTGTGCCGGGCCCTGATGAGCCGCCCTCGCCTGCTGCTGCTCGACGAGCCTTCGGCGGGCATGAC GCATGACGAGACCCATGAACTGATGGACGACATCCTGCAGGTGCGCGGCAAGCTGCAGGACCTGTCGGTGGTGCTGATCG AGCACGAAATGAACGTGATCGAGCGCATCACCGACCGCTGCATCGTGCTGAACTACGGCAAGAAGATTGCCGAGGGAACC TACGCCGAGATTACCGCCGATCCCGACGTGCAGACCGCCTATCTGGGGGAGGAAGCCGCATGA
Upstream 100 bases:
>100_bases TCCTGTTCTACGCGGCGCTGGTGATCGCCATCCTGCTGTTCCGCCCGGACGGCCTGATGCCGCGCAAGACCCGCCTGTTC TTTCCCCGGGAGGATGCGCA
Downstream 100 bases:
>100_bases GCGACAGCACACTGCGCGTGGAAGGGCTGACCACGGGCTACGACAGGGTCAACGTCCTGCACGATGTCTCGATCGAGGTG CCGCCGGGCAAGATCACATG
Product: ABC transporter ATPase
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein G [H]
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MSDAMIQVRDLTMRFGGLTALDNLQLEIRRGEILGLLGPNGSGKTTFFNVLTGLYKASAGTITYDGNNVIGKTPQQIYRS GVARTFQRSRLSLPLTVFDNIVIGDYQNMRHGLVFNLFRRKAFRAEYERYVESVRELLGIFSPPLVARLFEPVETFTMID RRRIEVCRALMSRPRLLLLDEPSAGMTHDETHELMDDILQVRGKLQDLSVVLIEHEMNVIERITDRCIVLNYGKKIAEGT YAEITADPDVQTAYLGEEAA
Sequences:
>Translated_260_residues MSDAMIQVRDLTMRFGGLTALDNLQLEIRRGEILGLLGPNGSGKTTFFNVLTGLYKASAGTITYDGNNVIGKTPQQIYRS GVARTFQRSRLSLPLTVFDNIVIGDYQNMRHGLVFNLFRRKAFRAEYERYVESVRELLGIFSPPLVARLFEPVETFTMID RRRIEVCRALMSRPRLLLLDEPSAGMTHDETHELMDDILQVRGKLQDLSVVLIEHEMNVIERITDRCIVLNYGKKIAEGT YAEITADPDVQTAYLGEEAA >Mature_259_residues SDAMIQVRDLTMRFGGLTALDNLQLEIRRGEILGLLGPNGSGKTTFFNVLTGLYKASAGTITYDGNNVIGKTPQQIYRSG VARTFQRSRLSLPLTVFDNIVIGDYQNMRHGLVFNLFRRKAFRAEYERYVESVRELLGIFSPPLVARLFEPVETFTMIDR RRIEVCRALMSRPRLLLLDEPSAGMTHDETHELMDDILQVRGKLQDLSVVLIEHEMNVIERITDRCIVLNYGKKIAEGTY AEITADPDVQTAYLGEEAA
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27881501, Length=228, Percent_Identity=28.0701754385965, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI30795238, Length=228, Percent_Identity=28.0701754385965, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI31657092, Length=224, Percent_Identity=24.1071428571429, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI116734710, Length=224, Percent_Identity=29.0178571428571, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI153792144, Length=214, Percent_Identity=26.6355140186916, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI105990541, Length=248, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI21536376, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI45446740, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI47078218, Length=221, Percent_Identity=24.4343891402715, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=39.2996108949416, Blast_Score=187, Evalue=7e-49, Organism=Escherichia coli, GI87082268, Length=256, Percent_Identity=30.46875, Blast_Score=117, Evalue=5e-28, Organism=Escherichia coli, GI48995001, Length=229, Percent_Identity=32.3144104803493, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI1789991, Length=258, Percent_Identity=29.8449612403101, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI1789593, Length=257, Percent_Identity=29.1828793774319, Blast_Score=98, Evalue=7e-22, Organism=Escherichia coli, GI1787792, Length=253, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1790190, Length=246, Percent_Identity=28.8617886178862, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788472, Length=246, Percent_Identity=26.8292682926829, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1787029, Length=251, Percent_Identity=25.8964143426295, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1790525, Length=261, Percent_Identity=27.2030651340996, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1788225, Length=254, Percent_Identity=27.1653543307087, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI48994943, Length=251, Percent_Identity=32.2709163346614, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787500, Length=234, Percent_Identity=28.6324786324786, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87081709, Length=243, Percent_Identity=27.1604938271605, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1788165, Length=246, Percent_Identity=27.6422764227642, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI87081791, Length=247, Percent_Identity=29.5546558704453, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1790162, Length=239, Percent_Identity=26.3598326359833, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786345, Length=254, Percent_Identity=30.3149606299213, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI48994883, Length=257, Percent_Identity=25.2918287937743, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=27.8969957081545, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788897, Length=224, Percent_Identity=25.8928571428571, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786253, Length=252, Percent_Identity=26.984126984127, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI87081782, Length=261, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1787370, Length=246, Percent_Identity=27.2357723577236, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=25.0965250965251, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787089, Length=247, Percent_Identity=27.5303643724696, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787712, Length=229, Percent_Identity=24.4541484716157, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1790544, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1786803, Length=249, Percent_Identity=25.7028112449799, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788506, Length=231, Percent_Identity=28.1385281385281, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789032, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789873, Length=223, Percent_Identity=25.1121076233184, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788210, Length=235, Percent_Identity=22.5531914893617, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1789586, Length=249, Percent_Identity=24.8995983935743, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1788644, Length=263, Percent_Identity=26.2357414448669, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1786703, Length=220, Percent_Identity=24.5454545454545, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790467, Length=245, Percent_Identity=23.265306122449, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI145693107, Length=263, Percent_Identity=24.7148288973384, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71983523, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI71983516, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI71983510, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI25146777, Length=230, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193208177, Length=233, Percent_Identity=24.8927038626609, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193209708, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221512771, Length=239, Percent_Identity=26.7782426778243, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643674, Length=241, Percent_Identity=25.7261410788382, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24666092, Length=242, Percent_Identity=23.5537190082645, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28573571, Length=255, Percent_Identity=26.2745098039216, Blast_Score=68, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 29420; Mature: 29289
Theoretical pI: Translated: 6.15; Mature: 6.15
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDAMIQVRDLTMRFGGLTALDNLQLEIRRGEILGLLGPNGSGKTTFFNVLTGLYKASAG CCCCCEEHHHHHHHHCCCCEECCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCC TITYDGNNVIGKTPQQIYRSGVARTFQRSRLSLPLTVFDNIVIGDYQNMRHGLVFNLFRR EEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCHHHHHHHHHHHHHHH KAFRAEYERYVESVRELLGIFSPPLVARLFEPVETFTMIDRRRIEVCRALMSRPRLLLLD HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE EPSAGMTHDETHELMDDILQVRGKLQDLSVVLIEHEMNVIERITDRCIVLNYGKKIAEGT CCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEHHHHHHHHHHHCCEEEEECCCHHHCCC YAEITADPDVQTAYLGEEAA EEEEECCCCCCEECCCCCCC >Mature Secondary Structure SDAMIQVRDLTMRFGGLTALDNLQLEIRRGEILGLLGPNGSGKTTFFNVLTGLYKASAG CCCCEEHHHHHHHHCCCCEECCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCCC TITYDGNNVIGKTPQQIYRSGVARTFQRSRLSLPLTVFDNIVIGDYQNMRHGLVFNLFRR EEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCEEECCHHHHHHHHHHHHHHH KAFRAEYERYVESVRELLGIFSPPLVARLFEPVETFTMIDRRRIEVCRALMSRPRLLLLD HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE EPSAGMTHDETHELMDDILQVRGKLQDLSVVLIEHEMNVIERITDRCIVLNYGKKIAEGT CCCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEEHHHHHHHHHHHCCEEEEECCCHHHCCC YAEITADPDVQTAYLGEEAA EEEEECCCCCCEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]