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The map label for this gene is gbpR [H]

Identifier: 116695785

GI number: 116695785

Start: 2088526

End: 2089533

Strand: Direct

Name: gbpR [H]

Synonym: H16_B1849

Alternate gene names: 116695785

Gene position: 2088526-2089533 (Clockwise)

Preceding gene: 116695781

Following gene: 116695787

Centisome position: 71.71

GC content: 69.64

Gene sequence:

>1008_bases
ATGCCCGCCGAAGCCTTCGCCCATACCCTGCTTGGCCGCCTCAAGCTGCGCCACCTGCGCATCATGCTGGCGCTGAGCGA
GATGCCAACCGCCGCAGCCGTCGCCGCGCGCTTTCATGTCAGCCCCGCCGCGGTGTCCAAGACCCTGGCCGAGATCGAAG
ACATCGTGGGCATGCCGCTGTTCGAGCGCAGCCGCCGCGGCCTGCACCTGACCGAGCCCGGACGGGAGATGGCAGCCCAT
GCGGCGGTCTTGCTGGCGCAGCTCGAACGGCTCGCCGAATCGCTGCAGGCAGTGCGTGCCGGCAGCCAGGGGGCGTTGCG
CATCGCGTTCCGGACAATGTCGGTGCAGCCCTTCCTGGCGCGGGCGATGAGCGACTTCTACCGTGACCATCCGCGCGTGG
AGATCAGCGTGATCGAAGGCGGCATCGGCGAACTGGCGGATCAACTGGTGGATGGCTCGCTGGACCTGCTGTTCGCCTAT
GACGATCCGCGCCTGTCGCTACCCGCGCTGCGCACGGCACCGGTAGTCCCGGCGCAGAAGGTGGTGATTGTCGCCAGCCT
GGACCATCCGCTGCTCACGCGCCGCAAGCTGGCGGCGCGGGAACTGTCCGGGCAGCAATGGTGCATTCCGGTGGCCGGCT
CGCGCATGCTTCACCTGCTGCACACGGCGTTTCATACCCTAGGGGCGCCGGCGCCCTCGCTGGGCATCCGCACCAGCGAT
GTGGCCGCCACGGCCAGCTTGTTGCAGGCTGGTCATTTCCTCGCGGTGTTCCCCGAGCGCATTGCCGCGCAGCTCACCCT
GGCCAAGGTGGCGCGAGTGCTTCGCTTCGAACTCGGCAGCCGCGTGGAGCCGGTGGTCGCGGTCTGGAACGACGAACTCA
CGCCACGCACGCCGGCGCGCCTGTTTCGCGAGCTCGTCATGCGTCGCGCCGGCGAGACCCTCGTGGCCGAGCCAGTGCCG
TTGCTGGCCGCGCGCGCGGTGGCGGCGGCCGGCGTTCGCAAGCGCTGA

Upstream 100 bases:

>100_bases
TCGGTTCCGATACCAAAAGCGAATAAAAATCGCTGTTTGTTGAGCAAATGGTTAACTTGTAGAATGAGCCACCCGGCCCC
GCCGATCGTCGCCTGCCCCC

Downstream 100 bases:

>100_bases
ACGGGAAGCCGGCCCGGCTCAGTGCGCGCACAGCACCGCAGCCATCTCCCTCGCCGCGCCCTGCAGCGTCGGCACCGCCT
GCAGCAGCGCCTCAAGCGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPAEAFAHTLLGRLKLRHLRIMLALSEMPTAAAVAARFHVSPAAVSKTLAEIEDIVGMPLFERSRRGLHLTEPGREMAAH
AAVLLAQLERLAESLQAVRAGSQGALRIAFRTMSVQPFLARAMSDFYRDHPRVEISVIEGGIGELADQLVDGSLDLLFAY
DDPRLSLPALRTAPVVPAQKVVIVASLDHPLLTRRKLAARELSGQQWCIPVAGSRMLHLLHTAFHTLGAPAPSLGIRTSD
VAATASLLQAGHFLAVFPERIAAQLTLAKVARVLRFELGSRVEPVVAVWNDELTPRTPARLFRELVMRRAGETLVAEPVP
LLAARAVAAAGVRKR

Sequences:

>Translated_335_residues
MPAEAFAHTLLGRLKLRHLRIMLALSEMPTAAAVAARFHVSPAAVSKTLAEIEDIVGMPLFERSRRGLHLTEPGREMAAH
AAVLLAQLERLAESLQAVRAGSQGALRIAFRTMSVQPFLARAMSDFYRDHPRVEISVIEGGIGELADQLVDGSLDLLFAY
DDPRLSLPALRTAPVVPAQKVVIVASLDHPLLTRRKLAARELSGQQWCIPVAGSRMLHLLHTAFHTLGAPAPSLGIRTSD
VAATASLLQAGHFLAVFPERIAAQLTLAKVARVLRFELGSRVEPVVAVWNDELTPRTPARLFRELVMRRAGETLVAEPVP
LLAARAVAAAGVRKR
>Mature_334_residues
PAEAFAHTLLGRLKLRHLRIMLALSEMPTAAAVAARFHVSPAAVSKTLAEIEDIVGMPLFERSRRGLHLTEPGREMAAHA
AVLLAQLERLAESLQAVRAGSQGALRIAFRTMSVQPFLARAMSDFYRDHPRVEISVIEGGIGELADQLVDGSLDLLFAYD
DPRLSLPALRTAPVVPAQKVVIVASLDHPLLTRRKLAARELSGQQWCIPVAGSRMLHLLHTAFHTLGAPAPSLGIRTSDV
AATASLLQAGHFLAVFPERIAAQLTLAKVARVLRFELGSRVEPVVAVWNDELTPRTPARLFRELVMRRAGETLVAEPVPL
LAARAVAAAGVRKR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790262, Length=204, Percent_Identity=28.921568627451, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI157672245, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787601, Length=253, Percent_Identity=21.3438735177866, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=203, Percent_Identity=26.1083743842365, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789506, Length=244, Percent_Identity=20.4918032786885, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787949, Length=139, Percent_Identity=30.2158273381295, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789440, Length=173, Percent_Identity=24.2774566473988, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.1369863013699, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36323; Mature: 36192

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEAFAHTLLGRLKLRHLRIMLALSEMPTAAAVAARFHVSPAAVSKTLAEIEDIVGMPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
FERSRRGLHLTEPGREMAAHAAVLLAQLERLAESLQAVRAGSQGALRIAFRTMSVQPFLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHH
RAMSDFYRDHPRVEISVIEGGIGELADQLVDGSLDLLFAYDDPRLSLPALRTAPVVPAQK
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
VVIVASLDHPLLTRRKLAARELSGQQWCIPVAGSRMLHLLHTAFHTLGAPAPSLGIRTSD
EEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
VAATASLLQAGHFLAVFPERIAAQLTLAKVARVLRFELGSRVEPVVAVWNDELTPRTPAR
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHH
LFRELVMRRAGETLVAEPVPLLAARAVAAAGVRKR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAEAFAHTLLGRLKLRHLRIMLALSEMPTAAAVAARFHVSPAAVSKTLAEIEDIVGMPL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
FERSRRGLHLTEPGREMAAHAAVLLAQLERLAESLQAVRAGSQGALRIAFRTMSVQPFLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHH
RAMSDFYRDHPRVEISVIEGGIGELADQLVDGSLDLLFAYDDPRLSLPALRTAPVVPAQK
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
VVIVASLDHPLLTRRKLAARELSGQQWCIPVAGSRMLHLLHTAFHTLGAPAPSLGIRTSD
EEEEEECCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHH
VAATASLLQAGHFLAVFPERIAAQLTLAKVARVLRFELGSRVEPVVAVWNDELTPRTPAR
HHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHH
LFRELVMRRAGETLVAEPVPLLAARAVAAAGVRKR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]