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The map label for this gene is kdgR [H]

Identifier: 116695742

GI number: 116695742

Start: 2043419

End: 2044474

Strand: Direct

Name: kdgR [H]

Synonym: H16_B1806

Alternate gene names: 116695742

Gene position: 2043419-2044474 (Clockwise)

Preceding gene: 116695741

Following gene: 116695743

Centisome position: 70.16

GC content: 68.18

Gene sequence:

>1056_bases
ATGCCGCGCCCTGTTATCCGACCTGTGTCCGACCAGAAACCTGCAGAGAAACTCACCATCCAGGACGTTGCCGACTATGC
GGGCGTGTCCAAGGCAACCGTATCGCGCTACCTGAACCGGGGCGGCGAGCAGCTTTCCGCGGACGTGGAGGCGCGCGTCG
CCGCGGCCATCCGCGCGCTCGGCTATAGCCCCAGCCCGATGGCGCAGGGGCTCAAGCGCGGCAAGTCGCGCCTGATCGGC
CTGGTGGTCGCGGATGTCTCCAATTCGTTCTCGGTGGCCGTGCTGCGCGGCGTTGAGAAGGCCTGTCGCGACGCCGGCTA
CATGGTGATGCTGTTCAACCTCGGCAATGACGAGCAACTGGAGCGCGAAGCCATTCGCTCGCTGTCGGCTTACCGGGTCG
AGGGCTTTATCCTGCACACGCTGGGCCACGATGCCGGCGCCCTGGCCGATGCGGCGCAGTTGGGCAAGCCAGTGGTCCTG
GTCGACCGCAAGGTCGGCGATGCCGAAGTCGACCTGGTGGCCCTGGACAACCAGACCGCCGTCCAGGAAGCCGCCGGCCA
CCTGGTCGAAGCCGGCTACCGGCGCCTGCTGTTCATCAGCGAGCCGATCAAGGCCATCAGCTCGCGCAACGAGCGGGCGC
GCGCGTTCCAGGCCTTTGTCGCCGAACACGTGGACACGGTTGGAGGGACCGTTTTTGAAGCCCAGCGGGGTGACGACGAT
GCCCTGGATGAAGCGCTGCGCGCGCTGCGCCGTGGCGCCGGACAGGCACCCGTTGCCGTGCTGGCGGCCAACGCCGTGAT
CTCGCTGCGCGTGGCCGCATCGGCCGCCAGACTAGGGTGGCAGCTTGGCGCCGACCTGGGCCTGATCGGCTTCGATGATC
CGGAATGGGCTGCACTGGTCGGTCCTGGCCTCAGCGCCATTTCCCAGCCCACCGACGATATCGGGCGCGTTGCCACCAAC
TGCCTGATAGAGCGCCTGCAAGGCACGCAGCTGCCGCCGCGCCGGGTGCTGTTGCCCGGCACGCTGGTCACGCGCGGATC
GACCCGCCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCCGCACCAGGTATCGGAGCCCAATCGCCCCGGAGGCTGGCGCATCCCCACACGCCCGAGGCATAATCGTGAAACTGGT
TTCACCGAGACCCGAACCCT

Downstream 100 bases:

>100_bases
TCGCAGAGCCCTTCCCCACCGGCGCCCGCCGTGCCCGCCTGATCCACGCCTGCACCCGCTGCGCACGTCCAGCGGGTGCC
TGACGTGCCTGTTTCCACAT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPRPVIRPVSDQKPAEKLTIQDVADYAGVSKATVSRYLNRGGEQLSADVEARVAAAIRALGYSPSPMAQGLKRGKSRLIG
LVVADVSNSFSVAVLRGVEKACRDAGYMVMLFNLGNDEQLEREAIRSLSAYRVEGFILHTLGHDAGALADAAQLGKPVVL
VDRKVGDAEVDLVALDNQTAVQEAAGHLVEAGYRRLLFISEPIKAISSRNERARAFQAFVAEHVDTVGGTVFEAQRGDDD
ALDEALRALRRGAGQAPVAVLAANAVISLRVAASAARLGWQLGADLGLIGFDDPEWAALVGPGLSAISQPTDDIGRVATN
CLIERLQGTQLPPRRVLLPGTLVTRGSTRRA

Sequences:

>Translated_351_residues
MPRPVIRPVSDQKPAEKLTIQDVADYAGVSKATVSRYLNRGGEQLSADVEARVAAAIRALGYSPSPMAQGLKRGKSRLIG
LVVADVSNSFSVAVLRGVEKACRDAGYMVMLFNLGNDEQLEREAIRSLSAYRVEGFILHTLGHDAGALADAAQLGKPVVL
VDRKVGDAEVDLVALDNQTAVQEAAGHLVEAGYRRLLFISEPIKAISSRNERARAFQAFVAEHVDTVGGTVFEAQRGDDD
ALDEALRALRRGAGQAPVAVLAANAVISLRVAASAARLGWQLGADLGLIGFDDPEWAALVGPGLSAISQPTDDIGRVATN
CLIERLQGTQLPPRRVLLPGTLVTRGSTRRA
>Mature_350_residues
PRPVIRPVSDQKPAEKLTIQDVADYAGVSKATVSRYLNRGGEQLSADVEARVAAAIRALGYSPSPMAQGLKRGKSRLIGL
VVADVSNSFSVAVLRGVEKACRDAGYMVMLFNLGNDEQLEREAIRSLSAYRVEGFILHTLGHDAGALADAAQLGKPVVLV
DRKVGDAEVDLVALDNQTAVQEAAGHLVEAGYRRLLFISEPIKAISSRNERARAFQAFVAEHVDTVGGTVFEAQRGDDDA
LDEALRALRRGAGQAPVAVLAANAVISLRVAASAARLGWQLGADLGLIGFDDPEWAALVGPGLSAISQPTDDIGRVATNC
LIERLQGTQLPPRRVLLPGTLVTRGSTRRA

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=337, Percent_Identity=29.9703264094956, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1790369, Length=339, Percent_Identity=30.6784660766962, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI48994940, Length=331, Percent_Identity=26.8882175226586, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=26.7267267267267, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789202, Length=329, Percent_Identity=27.9635258358663, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=26.4094955489614, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=29.2168674698795, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787906, Length=349, Percent_Identity=27.2206303724928, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789068, Length=333, Percent_Identity=24.024024024024, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=24.6246246246246, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790715, Length=341, Percent_Identity=22.5806451612903, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37256; Mature: 37125

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPVIRPVSDQKPAEKLTIQDVADYAGVSKATVSRYLNRGGEQLSADVEARVAAAIRAL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GYSPSPMAQGLKRGKSRLIGLVVADVSNSFSVAVLRGVEKACRDAGYMVMLFNLGNDEQL
CCCCCHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
EREAIRSLSAYRVEGFILHTLGHDAGALADAAQLGKPVVLVDRKVGDAEVDLVALDNQTA
HHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCHHH
VQEAAGHLVEAGYRRLLFISEPIKAISSRNERARAFQAFVAEHVDTVGGTVFEAQRGDDD
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
ALDEALRALRRGAGQAPVAVLAANAVISLRVAASAARLGWQLGADLGLIGFDDPEWAALV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHEE
GPGLSAISQPTDDIGRVATNCLIERLQGTQLPPRRVLLPGTLVTRGSTRRA
CCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCC
>Mature Secondary Structure 
PRPVIRPVSDQKPAEKLTIQDVADYAGVSKATVSRYLNRGGEQLSADVEARVAAAIRAL
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GYSPSPMAQGLKRGKSRLIGLVVADVSNSFSVAVLRGVEKACRDAGYMVMLFNLGNDEQL
CCCCCHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
EREAIRSLSAYRVEGFILHTLGHDAGALADAAQLGKPVVLVDRKVGDAEVDLVALDNQTA
HHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCHHH
VQEAAGHLVEAGYRRLLFISEPIKAISSRNERARAFQAFVAEHVDTVGGTVFEAQRGDDD
HHHHHHHHHHHCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
ALDEALRALRRGAGQAPVAVLAANAVISLRVAASAARLGWQLGADLGLIGFDDPEWAALV
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHEE
GPGLSAISQPTDDIGRVATNCLIERLQGTQLPPRRVLLPGTLVTRGSTRRA
CCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]