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The map label for this gene is rhbA [H]

Identifier: 116695631

GI number: 116695631

Start: 1921886

End: 1923310

Strand: Direct

Name: rhbA [H]

Synonym: H16_B1692

Alternate gene names: 116695631

Gene position: 1921886-1923310 (Clockwise)

Preceding gene: 116695630

Following gene: 116695636

Centisome position: 65.99

GC content: 71.44

Gene sequence:

>1425_bases
ATGACGCCTCCCTCGCTCGCCACGCATGCCCACGGCCAACCCGCGCCGTTCTCGGCTGGCGCCTTCGTCCGGCAAGCGCC
CATCCGGCTCGACGACAACCCCTACCTGCAGCGCCAGTCCGCGCGCGAGTCCAACGCCCGCTCCTATCCGCGCCGCATCC
CGCTGGCGCTGGAACAGGGCTATGGCGTGTATTTGCGCGATACCAGCGGCCAGCTCTTCATCGACTGCCTGGCCGGCGCC
GGCACGCTGGCGCTCGGCCACAACCACCCGGCAGTAGTGCGCGCGCTGCGCGACACGCTCGACAGCGGCCTGCCGCTGCA
TACGCTGGACCTGGCCACGCCGGTCAAGGACCGCTTTATCGACGACCTGTTCGGCCTGCTGCCGCCCGAGTTCGCAGCGC
GCGCCCGTATCCAGTTCTGCGGCCCGACCGGCGCCGACGGCATCGAGGCAGCGCTCAAGCTGGCCAAGACCGCCACCGGA
CGCCATACGGTGCTGAGCTTTGCCGGCGGCTACCACGGCATGACGCACGGCACGCTGGCGCTGATGGGCAACCTCGGCCC
CAAGGCGCCGCTGGGTGCGCTCGGCGGCAGCGTGCAGTTCCTGCCCTACCCGTATGACTACCGCTGCCCGTTCGGCCTGC
GCGGCGACGCCGGCATCGACGCGGGCCTGCGCTATATCGAGCAGATGCTGGCCGACCCGGAGTCCGGCGTGCTGCCGCCG
GCGGCGGTGGTGGTGGAAGCGGTACAGGGCGAAGGCGGCGTGATCCCCGCGCCCGCGCGCTGGCTGCGCGAACTGCGCCG
CATCACGCGCGAGTACGGCATCGCGCTGGTGCTCGACGAAGTGCAGACCGGGCTCGGCCGCACCGGGCGCATGTTCGCGT
TCGAGCATGCCGGCATCGTGCCGGACGTGCTGGTCCTGTCCAAGGCGATCGGCGGCAGCTTGCCGATGTCGGTGGTGATC
TACGACAGCGCGCTCGACGCGTGGCAACCGGGCGCGCACGCCGGCACCTTCCGCGGCAACCAGCTGGCGATGGCGGCGGG
CTCCGCCACCATCCGCACCCTGGTCGCGCAAGGCATCGTCGCCCATGCCGAGACCATGGGCCAGCGCCTCGCCACGCGGC
TGCGGCAGTTGCATACCGCGTGCCCCGCGATCGGCGAAGTGCGCGGGCGCGGCCTGATGATCGGGGTGGAACTGATCGAC
GAACGTGCCGAGGCCGATGCGGTGGGCGCCTACCCGGCCGACGGCACCTTCGCGCGCACGGTGCAACGCGAATGCCTGCA
GCGCGGGCTGATCGTCGAACTGGGCGGACGCCACGGCGCCACGGTGCGCTTCCTGCCACCGCTGGTCATCGGCGAGACCG
AGATCGACCTGGTGGCCGAGTTGTTTGGCGACGCAGTCAGCGCGGCGCACAAGCAATGCCGCTGA

Upstream 100 bases:

>100_bases
GCGAGCTGCCCCCGCGCGCGGGCCAACCCATCTTGCCCGGTCTCGATGCCGGGCCCCGCAGTCAACGTCCCTGTTCAACG
CCCCCGTTAGGAACGACACC

Downstream 100 bases:

>100_bases
GCGCTTGCGCGCCGTTCCGCGGTGGCCGGGGCCACCGCGGAACCAGCTTCAGGACGCGTCACCGCGCAGCATCTCGCGCA
GCCGGAATTTCTGGATCTTC

Product: putative aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTPPSLATHAHGQPAPFSAGAFVRQAPIRLDDNPYLQRQSARESNARSYPRRIPLALEQGYGVYLRDTSGQLFIDCLAGA
GTLALGHNHPAVVRALRDTLDSGLPLHTLDLATPVKDRFIDDLFGLLPPEFAARARIQFCGPTGADGIEAALKLAKTATG
RHTVLSFAGGYHGMTHGTLALMGNLGPKAPLGALGGSVQFLPYPYDYRCPFGLRGDAGIDAGLRYIEQMLADPESGVLPP
AAVVVEAVQGEGGVIPAPARWLRELRRITREYGIALVLDEVQTGLGRTGRMFAFEHAGIVPDVLVLSKAIGGSLPMSVVI
YDSALDAWQPGAHAGTFRGNQLAMAAGSATIRTLVAQGIVAHAETMGQRLATRLRQLHTACPAIGEVRGRGLMIGVELID
ERAEADAVGAYPADGTFARTVQRECLQRGLIVELGGRHGATVRFLPPLVIGETEIDLVAELFGDAVSAAHKQCR

Sequences:

>Translated_474_residues
MTPPSLATHAHGQPAPFSAGAFVRQAPIRLDDNPYLQRQSARESNARSYPRRIPLALEQGYGVYLRDTSGQLFIDCLAGA
GTLALGHNHPAVVRALRDTLDSGLPLHTLDLATPVKDRFIDDLFGLLPPEFAARARIQFCGPTGADGIEAALKLAKTATG
RHTVLSFAGGYHGMTHGTLALMGNLGPKAPLGALGGSVQFLPYPYDYRCPFGLRGDAGIDAGLRYIEQMLADPESGVLPP
AAVVVEAVQGEGGVIPAPARWLRELRRITREYGIALVLDEVQTGLGRTGRMFAFEHAGIVPDVLVLSKAIGGSLPMSVVI
YDSALDAWQPGAHAGTFRGNQLAMAAGSATIRTLVAQGIVAHAETMGQRLATRLRQLHTACPAIGEVRGRGLMIGVELID
ERAEADAVGAYPADGTFARTVQRECLQRGLIVELGGRHGATVRFLPPLVIGETEIDLVAELFGDAVSAAHKQCR
>Mature_473_residues
TPPSLATHAHGQPAPFSAGAFVRQAPIRLDDNPYLQRQSARESNARSYPRRIPLALEQGYGVYLRDTSGQLFIDCLAGAG
TLALGHNHPAVVRALRDTLDSGLPLHTLDLATPVKDRFIDDLFGLLPPEFAARARIQFCGPTGADGIEAALKLAKTATGR
HTVLSFAGGYHGMTHGTLALMGNLGPKAPLGALGGSVQFLPYPYDYRCPFGLRGDAGIDAGLRYIEQMLADPESGVLPPA
AVVVEAVQGEGGVIPAPARWLRELRRITREYGIALVLDEVQTGLGRTGRMFAFEHAGIVPDVLVLSKAIGGSLPMSVVIY
DSALDAWQPGAHAGTFRGNQLAMAAGSATIRTLVAQGIVAHAETMGQRLATRLRQLHTACPAIGEVRGRGLMIGVELIDE
RAEADAVGAYPADGTFARTVQRECLQRGLIVELGGRHGATVRFLPPLVIGETEIDLVAELFGDAVSAAHKQCR

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=28.175519630485, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4557809, Length=433, Percent_Identity=29.3302540415704, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI24119277, Length=429, Percent_Identity=27.039627039627, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=22.877358490566, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI284507298, Length=337, Percent_Identity=29.3768545994065, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI226442709, Length=393, Percent_Identity=23.1552162849873, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=21.9339622641509, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI188536080, Length=445, Percent_Identity=22.6966292134831, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679950, Length=445, Percent_Identity=22.6966292134831, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI38679946, Length=445, Percent_Identity=22.6966292134831, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787560, Length=409, Percent_Identity=35.2078239608802, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI145693181, Length=413, Percent_Identity=33.6561743341404, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1789016, Length=445, Percent_Identity=31.685393258427, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=30, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788044, Length=412, Percent_Identity=30.0970873786408, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI1786349, Length=333, Percent_Identity=29.7297297297297, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786991, Length=326, Percent_Identity=26.3803680981595, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=28.4064665127021, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144271, Length=435, Percent_Identity=25.9770114942529, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=450, Percent_Identity=25.3333333333333, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=256, Percent_Identity=30.078125, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=22.7678571428571, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=443, Percent_Identity=25.7336343115124, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6323470, Length=443, Percent_Identity=26.6365688487585, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321456, Length=378, Percent_Identity=25.9259259259259, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324386, Length=269, Percent_Identity=25.2788104089219, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=27.0642201834862, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=27.1889400921659, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21357415, Length=423, Percent_Identity=28.8416075650118, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=25.0574712643678, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281366494, Length=438, Percent_Identity=22.6027397260274, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667139, Length=438, Percent_Identity=22.6027397260274, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667143, Length=438, Percent_Identity=22.6027397260274, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 50298; Mature: 50167

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPSLATHAHGQPAPFSAGAFVRQAPIRLDDNPYLQRQSARESNARSYPRRIPLALEQG
CCCCCCCCCCCCCCCCCCCCCHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECC
YGVYLRDTSGQLFIDCLAGAGTLALGHNHPAVVRALRDTLDSGLPLHTLDLATPVKDRFI
CEEEEECCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
DDLFGLLPPEFAARARIQFCGPTGADGIEAALKLAKTATGRHTVLSFAGGYHGMTHGTLA
HHHHHCCCCCHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
LMGNLGPKAPLGALGGSVQFLPYPYDYRCPFGLRGDAGIDAGLRYIEQMLADPESGVLPP
EECCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
AAVVVEAVQGEGGVIPAPARWLRELRRITREYGIALVLDEVQTGLGRTGRMFAFEHAGIV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHCCCCCCCEEEECCCCCC
PDVLVLSKAIGGSLPMSVVIYDSALDAWQPGAHAGTFRGNQLAMAAGSATIRTLVAQGIV
HHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
AHAETMGQRLATRLRQLHTACPAIGEVRGRGLMIGVELIDERAEADAVGAYPADGTFART
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHH
VQRECLQRGLIVELGGRHGATVRFLPPLVIGETEIDLVAELFGDAVSAAHKQCR
HHHHHHHCCCEEEECCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPSLATHAHGQPAPFSAGAFVRQAPIRLDDNPYLQRQSARESNARSYPRRIPLALEQG
CCCCCCCCCCCCCCCCCCCCHHHCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECC
YGVYLRDTSGQLFIDCLAGAGTLALGHNHPAVVRALRDTLDSGLPLHTLDLATPVKDRFI
CEEEEECCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
DDLFGLLPPEFAARARIQFCGPTGADGIEAALKLAKTATGRHTVLSFAGGYHGMTHGTLA
HHHHHCCCCCHHHHCEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
LMGNLGPKAPLGALGGSVQFLPYPYDYRCPFGLRGDAGIDAGLRYIEQMLADPESGVLPP
EECCCCCCCCHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
AAVVVEAVQGEGGVIPAPARWLRELRRITREYGIALVLDEVQTGLGRTGRMFAFEHAGIV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHCCCCCCCEEEECCCCCC
PDVLVLSKAIGGSLPMSVVIYDSALDAWQPGAHAGTFRGNQLAMAAGSATIRTLVAQGIV
HHHHHHHHHHCCCCCEEEEEEECHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
AHAETMGQRLATRLRQLHTACPAIGEVRGRGLMIGVELIDERAEADAVGAYPADGTFART
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHH
VQRECLQRGLIVELGGRHGATVRFLPPLVIGETEIDLVAELFGDAVSAAHKQCR
HHHHHHHCCCEEEECCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]