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The map label for this gene is pgi [H]

Identifier: 116695443

GI number: 116695443

Start: 1687897

End: 1689531

Strand: Direct

Name: pgi [H]

Synonym: H16_B1502

Alternate gene names: 116695443

Gene position: 1687897-1689531 (Clockwise)

Preceding gene: 116695442

Following gene: 116695444

Centisome position: 57.95

GC content: 69.05

Gene sequence:

>1635_bases
ATGACCACTTCCCTGCCCGCCTGGCAAGCCCTGCGCGCGCACGCCGACACCCTGCGCGGCACCCATATGCGCGACTGGTT
CGAAGGCCCGCGCGGCCCGCTGCGCGCCGAGCGCTTCACCGCCGAAGCCTGCGGCCTGACGCTGGACTACGCCAAGAACC
GCATCACCGACGAAACGCTGGCGTTGCTGTTCACCCTGGCTGGCCAGGCGCGCGTGGCCGAGCGGCGCGACGCCATGTTC
GGCGGCGAACCGGTCAACACCACCGAGCACCGCGCAGCACTGCATATCGCGCTGCGCGCCTATCCGGAGGACGGCTATCG
CGCGCTCGGCGTGCCCGTGGGCGCTGACGTAGCCACGGTGCTGGCACAGATCGAGCGCTTTGCCAACGCGGTGCGCAGTG
GCGCCTGGACCGGGTTCGATGGCCGCGCGATCACCGACGTCGTCAATATCGGCATCGGCGGGTCGGACCTGGGCCCGCGC
ATGGTCTGCCGCGCGCTGAGCGATGCACAAACCACCGGCCCGCGCATGCACTTTGTCGCCAATGTCGACGGCAGCGATTT
GGCACGCACGCTGTCGGGGCTGGATGCCGCCACCACGCTGGTGATCGTCTGCTCCAAGACCTTCACCACGCTGGAAACCA
TGGCCAACGCCTGCACCGCGCGCGACTGGTTCCTGCAGCAAGGCGTGACCCGCGCCGGGCTGGCGCGCCATTTCGTGGCG
GTGTCGACCAACCGCGATGCGGTGGCCGAGTTCGGCATCGACCCGGCCAATATGTTCCCGTTCTGGGACTGGGTGGGCGG
ACGCTTCTCGCTGTGGTCCGCAGTGGGACTTTCGATCGCCGTGGCCATCGGCTTCGAGCGCTTCCGGCAATTGCTGGACG
GCGCGCGCGCGATGGACCTGCATTTCGCCAGCGCACCGCCCGAGCGCAACCTGCCGATGATCCTGGGCCTGCTCGACGTC
TGGTACCGCAGCTTCCTCGGCGCCGGCAGCCGCTGCGTGGCGCCCTACTGCGAGCCGCTGGAACTGCTGCCGGCCTTCCT
GCAGCAACTGGAAATGGAAAGCAACGGCAAGTCCGTGCGGCTTGACGGCGGCGCGCTCGATGCGGGCTCGGCCGCTGTGG
TATGGGGCACGACCGGCACCAACGGCCAGCACGCCTACTTCCAGATGATGCACCAGGGCTCGCAGCTGGTTCCGGTAGAC
TTCATCGCCACGCTGGAACCCGTGAGCGACTTGCCCGGCCACCATACCAAGCTGCTGGCCAACTGCTTTGCACAGGGCGA
GGCGCTGCTGCGCGGGCGCACCGCCGACGAAGTGCGCGCCGAGGGCGTGCGCGACGAAGCGCTGGTGCCGCACCTGGTGT
TCGAGGGCAACCGGCCCAGCAATACGCTGCTGCTGCAGCGGCTGGACCCGTACCACCTGGGCGCGCTGCTGGCGCTGTCG
GAACACCGCACCTTCGTGCAGGGTGCGCTGTGGCAGATCAATTCGTTTGACCAGTGGGGCGTGGAACTCGGCAAGAAACT
GGCCGCGCCGATCCAGCGCGAACTGGAAGGCACGGCCGGCGCCGCCGCGCATGATGCGTCGACGGCCGCACTGATCCGCC
GCGCCCAGGCAGTGCGGGCAACGGCCGCAGGCTAA

Upstream 100 bases:

>100_bases
CGCCGGCACCTGGGGCCCGGCAGCCTCCAGTGCCCTGCTGTCGCGAGACGGCATGGCCTGGCATGAAGAGATGTAGCCCA
CGTATTGCGGAGTATCTGAC

Downstream 100 bases:

>100_bases
CCCCGCGGCAAACAACACAGGAGACGCCGATGTCCACGCCCCTTCCCCGCTATGTCGTGTTCGGAGAAGCCCTGACCGAC
ATGGTCCGCCAGGCCGACGG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI 2; Phosphoglucose isomerase 2; PGI 2; Phosphohexose isomerase 2; PHI 2 [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTTSLPAWQALRAHADTLRGTHMRDWFEGPRGPLRAERFTAEACGLTLDYAKNRITDETLALLFTLAGQARVAERRDAMF
GGEPVNTTEHRAALHIALRAYPEDGYRALGVPVGADVATVLAQIERFANAVRSGAWTGFDGRAITDVVNIGIGGSDLGPR
MVCRALSDAQTTGPRMHFVANVDGSDLARTLSGLDAATTLVIVCSKTFTTLETMANACTARDWFLQQGVTRAGLARHFVA
VSTNRDAVAEFGIDPANMFPFWDWVGGRFSLWSAVGLSIAVAIGFERFRQLLDGARAMDLHFASAPPERNLPMILGLLDV
WYRSFLGAGSRCVAPYCEPLELLPAFLQQLEMESNGKSVRLDGGALDAGSAAVVWGTTGTNGQHAYFQMMHQGSQLVPVD
FIATLEPVSDLPGHHTKLLANCFAQGEALLRGRTADEVRAEGVRDEALVPHLVFEGNRPSNTLLLQRLDPYHLGALLALS
EHRTFVQGALWQINSFDQWGVELGKKLAAPIQRELEGTAGAAAHDASTAALIRRAQAVRATAAG

Sequences:

>Translated_544_residues
MTTSLPAWQALRAHADTLRGTHMRDWFEGPRGPLRAERFTAEACGLTLDYAKNRITDETLALLFTLAGQARVAERRDAMF
GGEPVNTTEHRAALHIALRAYPEDGYRALGVPVGADVATVLAQIERFANAVRSGAWTGFDGRAITDVVNIGIGGSDLGPR
MVCRALSDAQTTGPRMHFVANVDGSDLARTLSGLDAATTLVIVCSKTFTTLETMANACTARDWFLQQGVTRAGLARHFVA
VSTNRDAVAEFGIDPANMFPFWDWVGGRFSLWSAVGLSIAVAIGFERFRQLLDGARAMDLHFASAPPERNLPMILGLLDV
WYRSFLGAGSRCVAPYCEPLELLPAFLQQLEMESNGKSVRLDGGALDAGSAAVVWGTTGTNGQHAYFQMMHQGSQLVPVD
FIATLEPVSDLPGHHTKLLANCFAQGEALLRGRTADEVRAEGVRDEALVPHLVFEGNRPSNTLLLQRLDPYHLGALLALS
EHRTFVQGALWQINSFDQWGVELGKKLAAPIQRELEGTAGAAAHDASTAALIRRAQAVRATAAG
>Mature_543_residues
TTSLPAWQALRAHADTLRGTHMRDWFEGPRGPLRAERFTAEACGLTLDYAKNRITDETLALLFTLAGQARVAERRDAMFG
GEPVNTTEHRAALHIALRAYPEDGYRALGVPVGADVATVLAQIERFANAVRSGAWTGFDGRAITDVVNIGIGGSDLGPRM
VCRALSDAQTTGPRMHFVANVDGSDLARTLSGLDAATTLVIVCSKTFTTLETMANACTARDWFLQQGVTRAGLARHFVAV
STNRDAVAEFGIDPANMFPFWDWVGGRFSLWSAVGLSIAVAIGFERFRQLLDGARAMDLHFASAPPERNLPMILGLLDVW
YRSFLGAGSRCVAPYCEPLELLPAFLQQLEMESNGKSVRLDGGALDAGSAAVVWGTTGTNGQHAYFQMMHQGSQLVPVDF
IATLEPVSDLPGHHTKLLANCFAQGEALLRGRTADEVRAEGVRDEALVPHLVFEGNRPSNTLLLQRLDPYHLGALLALSE
HRTFVQGALWQINSFDQWGVELGKKLAAPIQRELEGTAGAAAHDASTAALIRRAQAVRATAAG

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=503, Percent_Identity=48.7077534791253, Blast_Score=509, Evalue=1e-144,
Organism=Homo sapiens, GI296080693, Length=503, Percent_Identity=44.7316103379722, Blast_Score=450, Evalue=1e-126,
Organism=Escherichia coli, GI1790457, Length=549, Percent_Identity=48.9981785063752, Blast_Score=525, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71996708, Length=536, Percent_Identity=48.5074626865672, Blast_Score=513, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI71996703, Length=536, Percent_Identity=48.5074626865672, Blast_Score=512, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6319673, Length=542, Percent_Identity=46.8634686346863, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24651916, Length=544, Percent_Identity=48.8970588235294, Blast_Score=515, Evalue=1e-146,
Organism=Drosophila melanogaster, GI24651914, Length=544, Percent_Identity=48.8970588235294, Blast_Score=515, Evalue=1e-146,
Organism=Drosophila melanogaster, GI17737445, Length=544, Percent_Identity=48.8970588235294, Blast_Score=515, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 58724; Mature: 58593

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSLPAWQALRAHADTLRGTHMRDWFEGPRGPLRAERFTAEACGLTLDYAKNRITDETL
CCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCEEHHHHHCCCCHHHH
ALLFTLAGQARVAERRDAMFGGEPVNTTEHRAALHIALRAYPEDGYRALGVPVGADVATV
HHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCCCCCEEECCCCCHHHHHH
LAQIERFANAVRSGAWTGFDGRAITDVVNIGIGGSDLGPRMVCRALSDAQTTGPRMHFVA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
NVDGSDLARTLSGLDAATTLVIVCSKTFTTLETMANACTARDWFLQQGVTRAGLARHFVA
ECCHHHHHHHHHCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEE
VSTNRDAVAEFGIDPANMFPFWDWVGGRFSLWSAVGLSIAVAIGFERFRQLLDGARAMDL
EECCCHHHHHCCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
HFASAPPERNLPMILGLLDVWYRSFLGAGSRCVAPYCEPLELLPAFLQQLEMESNGKSVR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LDGGALDAGSAAVVWGTTGTNGQHAYFQMMHQGSQLVPVDFIATLEPVSDLPGHHTKLLA
ECCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCHHHHHHH
NCFAQGEALLRGRTADEVRAEGVRDEALVPHLVFEGNRPSNTLLLQRLDPYHLGALLALS
HHHHCCHHHHCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHH
EHRTFVQGALWQINSFDQWGVELGKKLAAPIQRELEGTAGAAAHDASTAALIRRAQAVRA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TAAG
HCCC
>Mature Secondary Structure 
TTSLPAWQALRAHADTLRGTHMRDWFEGPRGPLRAERFTAEACGLTLDYAKNRITDETL
CCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHCEEHHHHHCCCCHHHH
ALLFTLAGQARVAERRDAMFGGEPVNTTEHRAALHIALRAYPEDGYRALGVPVGADVATV
HHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEECCCCCCEEECCCCCHHHHHH
LAQIERFANAVRSGAWTGFDGRAITDVVNIGIGGSDLGPRMVCRALSDAQTTGPRMHFVA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEE
NVDGSDLARTLSGLDAATTLVIVCSKTFTTLETMANACTARDWFLQQGVTRAGLARHFVA
ECCHHHHHHHHHCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEE
VSTNRDAVAEFGIDPANMFPFWDWVGGRFSLWSAVGLSIAVAIGFERFRQLLDGARAMDL
EECCCHHHHHCCCCHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
HFASAPPERNLPMILGLLDVWYRSFLGAGSRCVAPYCEPLELLPAFLQQLEMESNGKSVR
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
LDGGALDAGSAAVVWGTTGTNGQHAYFQMMHQGSQLVPVDFIATLEPVSDLPGHHTKLLA
ECCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCHHHHHHHCHHHCCCCHHHHHHH
NCFAQGEALLRGRTADEVRAEGVRDEALVPHLVFEGNRPSNTLLLQRLDPYHLGALLALS
HHHHCCHHHHCCCCHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHHHHH
EHRTFVQGALWQINSFDQWGVELGKKLAAPIQRELEGTAGAAAHDASTAALIRRAQAVRA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
TAAG
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA