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The map label for this gene is hchA [H]

Identifier: 116695291

GI number: 116695291

Start: 1493398

End: 1494279

Strand: Direct

Name: hchA [H]

Synonym: H16_B1347

Alternate gene names: 116695291

Gene position: 1493398-1494279 (Clockwise)

Preceding gene: 116695290

Following gene: 116695292

Centisome position: 51.28

GC content: 56.46

Gene sequence:

>882_bases
ATGACGTCCCAGACCGACAGCAAGCAGCCGACGCCTGACCCAGCCGAGCACAAGGCGTTCTTTCCCTCCCCATACTCGCT
CTCACAATTCACATCGCCAAAGTCGAACCTCTCCGACGCCGACTATCCGGACGCTTATCGGGGAGGTCGCTGGAAAGTAC
TACTCGTCGCTGCGGACGAGCGCTATCTCCTGACCGGAAACGGTACCTTCTTTTCTACTGGCAACCATCCCGTCGAGACC
CTGCTGCCGATGTATCACCTGGACCGCGCGGGCTTCGAGTTCGACATTGCCACTTTATCGGGCAATCCGACCAAGTTCGA
ATGGTGGGCGTTCCCTTCTGAGGACGCCGAGATAAAGTCCCTCTACGCGAAGTACGAGCAAAAATTTCAACAGCCCCTTA
AGCTTGCTGACGTAGTCAATTCGTTGGACAAGGACGCAAACTACATTGCCGTTTTTATCCCTGGGGGACATGGCGCCCTG
ATGGGGCTGCCCTTCAGCGCAGATATGAAGGCAACCCTTCAGTGGGCCATGCAAAACGACAGGTTCATCATCACGCTGTG
TCATGGGCCTGCGGCCCTGCTTTCCGCCGGCGTCGACGAACCTAACGGGGGAGACCTGTTCCGCGGCTACCGCATCTGCG
CATTCCCGGATTCCATGGACAAGCAGACGCCAGATATTGGCTATATGCCCGGCCCATTGCGTTGGTTCTTTGGAGAGAAA
CTCGCAGCGATGGGAGTAGAGATCGTCAATACTAAAATTGATGGGAGTACTTTCCGTGACCGGAAGCTCCTCACAGGCGA
TAGTCCATTCGCTGGCAACAATCTTGGCAAACTGGCTGCGCGCGCGTTACTGGAAGAAGTGCAGAGTACGGGTGCGCGCT
AG

Upstream 100 bases:

>100_bases
ATGCATGGTCCTTGCTGGTGATCGGGGGAATTCCCCATTTGATGTAAAAAAAGCCGGTGAAAACTAAGCTCTAGAACTGA
TTTTTAGAAGGAAGCCTATC

Downstream 100 bases:

>100_bases
TCCTCACACCATCATGGACTTCGTCTGCTCGGGCGCATGATTAAATTGCCTGCGCAAACCGTGATAACGCCTCTGGCGGC
GAGAGACCATTCTCCGGTCC

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTSQTDSKQPTPDPAEHKAFFPSPYSLSQFTSPKSNLSDADYPDAYRGGRWKVLLVAADERYLLTGNGTFFSTGNHPVET
LLPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSEDAEIKSLYAKYEQKFQQPLKLADVVNSLDKDANYIAVFIPGGHGAL
MGLPFSADMKATLQWAMQNDRFIITLCHGPAALLSAGVDEPNGGDLFRGYRICAFPDSMDKQTPDIGYMPGPLRWFFGEK
LAAMGVEIVNTKIDGSTFRDRKLLTGDSPFAGNNLGKLAARALLEEVQSTGAR

Sequences:

>Translated_293_residues
MTSQTDSKQPTPDPAEHKAFFPSPYSLSQFTSPKSNLSDADYPDAYRGGRWKVLLVAADERYLLTGNGTFFSTGNHPVET
LLPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSEDAEIKSLYAKYEQKFQQPLKLADVVNSLDKDANYIAVFIPGGHGAL
MGLPFSADMKATLQWAMQNDRFIITLCHGPAALLSAGVDEPNGGDLFRGYRICAFPDSMDKQTPDIGYMPGPLRWFFGEK
LAAMGVEIVNTKIDGSTFRDRKLLTGDSPFAGNNLGKLAARALLEEVQSTGAR
>Mature_292_residues
TSQTDSKQPTPDPAEHKAFFPSPYSLSQFTSPKSNLSDADYPDAYRGGRWKVLLVAADERYLLTGNGTFFSTGNHPVETL
LPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSEDAEIKSLYAKYEQKFQQPLKLADVVNSLDKDANYIAVFIPGGHGALM
GLPFSADMKATLQWAMQNDRFIITLCHGPAALLSAGVDEPNGGDLFRGYRICAFPDSMDKQTPDIGYMPGPLRWFFGEKL
AAMGVEIVNTKIDGSTFRDRKLLTGDSPFAGNNLGKLAARALLEEVQSTGAR

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=284, Percent_Identity=60.2112676056338, Blast_Score=353, Evalue=6e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 32296; Mature: 32165

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQTDSKQPTPDPAEHKAFFPSPYSLSQFTSPKSNLSDADYPDAYRGGRWKVLLVAADE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
RYLLTGNGTFFSTGNHPVETLLPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSEDAEIKS
EEEEECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHH
LYAKYEQKFQQPLKLADVVNSLDKDANYIAVFIPGGHGALMGLPFSADMKATLQWAMQND
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHEEECCC
RFIITLCHGPAALLSAGVDEPNGGDLFRGYRICAFPDSMDKQTPDIGYMPGPLRWFFGEK
CEEEEECCCCHHHHHCCCCCCCCCCEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
LAAMGVEIVNTKIDGSTFRDRKLLTGDSPFAGNNLGKLAARALLEEVQSTGAR
HHHCCEEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSQTDSKQPTPDPAEHKAFFPSPYSLSQFTSPKSNLSDADYPDAYRGGRWKVLLVAADE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
RYLLTGNGTFFSTGNHPVETLLPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSEDAEIKS
EEEEECCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCHHHHH
LYAKYEQKFQQPLKLADVVNSLDKDANYIAVFIPGGHGALMGLPFSADMKATLQWAMQND
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCHHHHHHEEECCC
RFIITLCHGPAALLSAGVDEPNGGDLFRGYRICAFPDSMDKQTPDIGYMPGPLRWFFGEK
CEEEEECCCCHHHHHCCCCCCCCCCEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
LAAMGVEIVNTKIDGSTFRDRKLLTGDSPFAGNNLGKLAARALLEEVQSTGAR
HHHCCEEEEEEECCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA