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The map label for this gene is yfcX [C]

Identifier: 116695290

GI number: 116695290

Start: 1492238

End: 1493203

Strand: Direct

Name: yfcX [C]

Synonym: H16_B1346

Alternate gene names: 116695290

Gene position: 1492238-1493203 (Clockwise)

Preceding gene: 116695289

Following gene: 116695291

Centisome position: 51.24

GC content: 61.18

Gene sequence:

>966_bases
ATGTCGACTATCTCCAGGCGTTCATTTGTCCAGTCCGTCGGCGCTGCAACACTCGCGCCGGGAATGTTGCTCGTCTCGGC
CGAAACTGGGGCCGCGTCCGAAAGCTCCGCTTCGCCCCAAGGGGCCAGCGCAAACTACGCCGATTACAAACATATCCAGG
TCACCAAAGACCACGGCGTCGCCACCGTAACATTGAACTATGCGCCGCTCAACCTGCTCGATGAGGTACTGTCGGATGAG
TTCGATCGGGTGACCCGACAACTGGAACAGGATGCGAGCGTACGCGTCATCATCCTGCAGAGCGCTGTGCCGAAATTCTT
TATCGCACACTCGGGCCTGCACCGTGTCGGCTCGGCGCCGAAGACGACTTCGAATACACGCACATTCCGTCTGACCCAGA
TGCTCGGAGAGCGCCTGCGCAACATGCCAAAAGCCGTGATCGCAAAGGTCGAAGGCATCGCTCGTGGTGGTGGCTGCGAG
ATCGCGCTGGCCGCGGACATGTGTTTCGCCGCGATCGGCAAGGCTGTGTTCGGCCAGCCGGAAGTCGTCTGCGGACTCGT
CCCCGGCGGGGGCAACACACAGCGCCTGCCGCGGCGCATGGGGCGCGCACGTGCCCTTGAGGTGCTGCTCGTCGGCGGAG
ACTTCTCGGCAGAACTGGCCGACCACTACGGTTATATCAATCGAGCGCTGCCGGCAGGAGAACTGGGGCAATTCGTGGAC
AAGCTCGCCCGCCGCATTGCAACCTTCCCCACCACCACGATTGCCCATCTGAAAAAGGCCGTGGACATGGGGTCGGACGT
ATCGTTCTCCGAAGGGTTGTTGATGGAAGCGCATGAGGCCGACCTTTGCGTAGCCAACGAAGCGATACAGGCGCGGGTCA
AGGCGATACTCAAAGCTGGCGCTGAGACCTACGAAGGCGAACTCCATTTTCCTGAACTGTCCGCGAAGCTGCCGCCCGCC
GATTAA

Upstream 100 bases:

>100_bases
ACCGCGACGCCCCGGTGGAGGGCAACCGCATCACTCGACCCGCCGCGAACTACGGGCCAAGCCTGGCTCGGCAAGCGGTA
GATGAATCCAAGGACCTGCC

Downstream 100 bases:

>100_bases
GCGATCGACCTGCGTCCGAACCGTGGTTGCCCGCAAGTGCGAAAAAAACATTGATACGAGCGGGAAGGTGAAGTGCACAT
AGCAAGGCGCCGGAATGCAT

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSTISRRSFVQSVGAATLAPGMLLVSAETGAASESSASPQGASANYADYKHIQVTKDHGVATVTLNYAPLNLLDEVLSDE
FDRVTRQLEQDASVRVIILQSAVPKFFIAHSGLHRVGSAPKTTSNTRTFRLTQMLGERLRNMPKAVIAKVEGIARGGGCE
IALAADMCFAAIGKAVFGQPEVVCGLVPGGGNTQRLPRRMGRARALEVLLVGGDFSAELADHYGYINRALPAGELGQFVD
KLARRIATFPTTTIAHLKKAVDMGSDVSFSEGLLMEAHEADLCVANEAIQARVKAILKAGAETYEGELHFPELSAKLPPA
D

Sequences:

>Translated_321_residues
MSTISRRSFVQSVGAATLAPGMLLVSAETGAASESSASPQGASANYADYKHIQVTKDHGVATVTLNYAPLNLLDEVLSDE
FDRVTRQLEQDASVRVIILQSAVPKFFIAHSGLHRVGSAPKTTSNTRTFRLTQMLGERLRNMPKAVIAKVEGIARGGGCE
IALAADMCFAAIGKAVFGQPEVVCGLVPGGGNTQRLPRRMGRARALEVLLVGGDFSAELADHYGYINRALPAGELGQFVD
KLARRIATFPTTTIAHLKKAVDMGSDVSFSEGLLMEAHEADLCVANEAIQARVKAILKAGAETYEGELHFPELSAKLPPA
D
>Mature_320_residues
STISRRSFVQSVGAATLAPGMLLVSAETGAASESSASPQGASANYADYKHIQVTKDHGVATVTLNYAPLNLLDEVLSDEF
DRVTRQLEQDASVRVIILQSAVPKFFIAHSGLHRVGSAPKTTSNTRTFRLTQMLGERLRNMPKAVIAKVEGIARGGGCEI
ALAADMCFAAIGKAVFGQPEVVCGLVPGGGNTQRLPRRMGRARALEVLLVGGDFSAELADHYGYINRALPAGELGQFVDK
LARRIATFPTTTIAHLKKAVDMGSDVSFSEGLLMEAHEADLCVANEAIQARVKAILKAGAETYEGELHFPELSAKLPPAD

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=239, Percent_Identity=30.9623430962343, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI20127408, Length=226, Percent_Identity=28.3185840707965, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI68989263, Length=265, Percent_Identity=28.6792452830189, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI31542718, Length=159, Percent_Identity=29.559748427673, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788682, Length=190, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=28.515625, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI221142681, Length=225, Percent_Identity=32, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787660, Length=225, Percent_Identity=32, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790281, Length=98, Percent_Identity=38.7755102040816, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=222, Percent_Identity=31.5315315315315, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=225, Percent_Identity=31.5555555555556, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=30.3964757709251, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508951, Length=180, Percent_Identity=30, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25144276, Length=180, Percent_Identity=30, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=180, Percent_Identity=30, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129971, Length=237, Percent_Identity=31.6455696202532, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24653477, Length=237, Percent_Identity=31.6455696202532, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=29.7959183673469, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24583077, Length=223, Percent_Identity=30.0448430493274, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583079, Length=223, Percent_Identity=30.0448430493274, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921000, Length=223, Percent_Identity=30.0448430493274, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654903, Length=241, Percent_Identity=26.1410788381743, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 34116; Mature: 33985

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISRRSFVQSVGAATLAPGMLLVSAETGAASESSASPQGASANYADYKHIQVTKDHGV
CCCCHHHHHHHHHCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCE
ATVTLNYAPLNLLDEVLSDEFDRVTRQLEQDASVRVIILQSAVPKFFIAHSGLHRVGSAP
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCHHHHCCCC
KTTSNTRTFRLTQMLGERLRNMPKAVIAKVEGIARGGGCEIALAADMCFAAIGKAVFGQP
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCC
EVVCGLVPGGGNTQRLPRRMGRARALEVLLVGGDFSAELADHYGYINRALPAGELGQFVD
CEEEEEECCCCCHHHHHHHHCHHHEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHH
KLARRIATFPTTTIAHLKKAVDMGSDVSFSEGLLMEAHEADLCVANEAIQARVKAILKAG
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
AETYEGELHFPELSAKLPPAD
CHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
STISRRSFVQSVGAATLAPGMLLVSAETGAASESSASPQGASANYADYKHIQVTKDHGV
CCCHHHHHHHHHCHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCE
ATVTLNYAPLNLLDEVLSDEFDRVTRQLEQDASVRVIILQSAVPKFFIAHSGLHRVGSAP
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCHHHHCCCC
KTTSNTRTFRLTQMLGERLRNMPKAVIAKVEGIARGGGCEIALAADMCFAAIGKAVFGQP
CCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCC
EVVCGLVPGGGNTQRLPRRMGRARALEVLLVGGDFSAELADHYGYINRALPAGELGQFVD
CEEEEEECCCCCHHHHHHHHCHHHEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHH
KLARRIATFPTTTIAHLKKAVDMGSDVSFSEGLLMEAHEADLCVANEAIQARVKAILKAG
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
AETYEGELHFPELSAKLPPAD
CHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA