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The map label for this gene is ampC [H]

Identifier: 116695245

GI number: 116695245

Start: 1457906

End: 1459096

Strand: Direct

Name: ampC [H]

Synonym: H16_B1301

Alternate gene names: 116695245

Gene position: 1457906-1459096 (Clockwise)

Preceding gene: 116695244

Following gene: 116695246

Centisome position: 50.06

GC content: 66.58

Gene sequence:

>1191_bases
ATGAAACGGATTCCTGTTGCCCGCATCGCCACCATCGCCATGGCTTGCAGCCTCTTCGCGGCCAATGCCAGTGCCGCCGA
CAGTGTCGGCCAGCGCCAGATAGAACGCGCTGTGAACGATGCCATCCGCCCCCTGATGGCGGCGCACGGCGTCCCCGGCA
TGGCCGTTGCCGTCACGGCCGGCGGCAAGCGCTACGTCTTCAACTACGGCGTCGCGGCGAAGGAGGGCCGGCGCAAGGTC
GACGGCGACACGCTCTTCGAGATCGGCTCGGTCAGCAAGACCTTCACCGCGACGCTCGCGTCCTATGGACAGGCCCGCGG
CACCCTGTCCCTGGCCGACCCTGCCGGGAAATACCTGCCGGCGCTTGCGGGAAGCAGCCTGGGCGCGACCAGCCTGCTCG
ACCTCGGCACCTATGCCGCCGGCGGCCTGCCGCTGCAGTTTCCGGATGCGGTCACCGATACCAGGACGATGGTCGACTAT
TTCCGGGGCTGGCGCCCCAGATATGCCGCCGGCAGCCATCGCCAGTATTCGAATCCCAGCATCGGCTTGTTCGGCTACCT
GGCCGCCAGCAGCATGGGCCAGCCCTTCGATGACCTGATGGAGAAGACGCTGTTCCCGGCGCTGGGCCTGGCCCACACCT
ACATCAGGGTGCCGAAGGCGCGCATGGGCGACTACGCCTATGGCTATTCGAAAGACGGCAAGCCGGTCCGCGTGACGCCC
GGCGTGCTGGATGCCGAAGCCTACGGCGTGAAAACCACGGCGGCCGACATGATCCGCTTTGTCGAAGCCAACATCGACAG
TGCCGGCCTGGACGACAAGCTGCGGCGTGCCATTGCCGGGACGCACACCGGGTACTTCAAGGTCGGCGACATGGTGCAGG
GGCTGGGCTGGGAAATGTACGCCTGGCCCACACGGGTCGACAGCGTGCTGGCCGGCAGTTCACCGCAGGTCGTGCTCGAG
GCGAACCAGGTGAGCCGGCTGGAGCCGCCGCTGTCATCGCCCGCCGATGTGCTGGTCAACAAGACCGGCTCGACCAATGG
CTTTGGCGCCTACGTGGTCTTTGTGCCGGCGAAGCGGATTGGCATCGTGATGCTGGCGAACAAGAACTTCCCGGTACCGG
AGCGGGTAAAGGCAGCGTTTCGGATACTGGCGGCCCTGGACGGTGCGCCGGGACGGGCGGATACCCCGTAA

Upstream 100 bases:

>100_bases
TGTCCTTCTGCAGCCGCTCCAGTTGCGCGTCCGTGCCGCCACGGGCGCGCACCGCCATGGTCCGGCGCCGCCCCCCCAGC
ATGATCGCCAAGCGCCGGAT

Downstream 100 bases:

>100_bases
GGGGAGGGTGGGGCTGCGTCATGCATCGCAGGCCTGTCCAGCGGCTGGTCCGCAAAAAATCCGGCTTTCCATGGAATAGT
CCACGCCCTCCATGTGTATA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKRIPVARIATIAMACSLFAANASAADSVGQRQIERAVNDAIRPLMAAHGVPGMAVAVTAGGKRYVFNYGVAAKEGRRKV
DGDTLFEIGSVSKTFTATLASYGQARGTLSLADPAGKYLPALAGSSLGATSLLDLGTYAAGGLPLQFPDAVTDTRTMVDY
FRGWRPRYAAGSHRQYSNPSIGLFGYLAASSMGQPFDDLMEKTLFPALGLAHTYIRVPKARMGDYAYGYSKDGKPVRVTP
GVLDAEAYGVKTTAADMIRFVEANIDSAGLDDKLRRAIAGTHTGYFKVGDMVQGLGWEMYAWPTRVDSVLAGSSPQVVLE
ANQVSRLEPPLSSPADVLVNKTGSTNGFGAYVVFVPAKRIGIVMLANKNFPVPERVKAAFRILAALDGAPGRADTP

Sequences:

>Translated_396_residues
MKRIPVARIATIAMACSLFAANASAADSVGQRQIERAVNDAIRPLMAAHGVPGMAVAVTAGGKRYVFNYGVAAKEGRRKV
DGDTLFEIGSVSKTFTATLASYGQARGTLSLADPAGKYLPALAGSSLGATSLLDLGTYAAGGLPLQFPDAVTDTRTMVDY
FRGWRPRYAAGSHRQYSNPSIGLFGYLAASSMGQPFDDLMEKTLFPALGLAHTYIRVPKARMGDYAYGYSKDGKPVRVTP
GVLDAEAYGVKTTAADMIRFVEANIDSAGLDDKLRRAIAGTHTGYFKVGDMVQGLGWEMYAWPTRVDSVLAGSSPQVVLE
ANQVSRLEPPLSSPADVLVNKTGSTNGFGAYVVFVPAKRIGIVMLANKNFPVPERVKAAFRILAALDGAPGRADTP
>Mature_396_residues
MKRIPVARIATIAMACSLFAANASAADSVGQRQIERAVNDAIRPLMAAHGVPGMAVAVTAGGKRYVFNYGVAAKEGRRKV
DGDTLFEIGSVSKTFTATLASYGQARGTLSLADPAGKYLPALAGSSLGATSLLDLGTYAAGGLPLQFPDAVTDTRTMVDY
FRGWRPRYAAGSHRQYSNPSIGLFGYLAASSMGQPFDDLMEKTLFPALGLAHTYIRVPKARMGDYAYGYSKDGKPVRVTP
GVLDAEAYGVKTTAADMIRFVEANIDSAGLDDKLRRAIAGTHTGYFKVGDMVQGLGWEMYAWPTRVDSVLAGSSPQVVLE
ANQVSRLEPPLSSPADVLVNKTGSTNGFGAYVVFVPAKRIGIVMLANKNFPVPERVKAAFRILAALDGAPGRADTP

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=377, Percent_Identity=45.8885941644562, Blast_Score=337, Evalue=6e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 41941; Mature: 41941

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIPVARIATIAMACSLFAANASAADSVGQRQIERAVNDAIRPLMAAHGVPGMAVAVTA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GGKRYVFNYGVAAKEGRRKVDGDTLFEIGSVSKTFTATLASYGQARGTLSLADPAGKYLP
CCCEEEEECCCCCCCCCCCCCCCHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHH
ALAGSSLGATSLLDLGTYAAGGLPLQFPDAVTDTRTMVDYFRGWRPRYAAGSHRQYSNPS
HHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
IGLFGYLAASSMGQPFDDLMEKTLFPALGLAHTYIRVPKARMGDYAYGYSKDGKPVRVTP
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECC
GVLDAEAYGVKTTAADMIRFVEANIDSAGLDDKLRRAIAGTHTGYFKVGDMVQGLGWEMY
CCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHCCCCEEE
AWPTRVDSVLAGSSPQVVLEANQVSRLEPPLSSPADVLVNKTGSTNGFGAYVVFVPAKRI
ECCHHHHHHHCCCCCCEEEECCHHHHCCCCCCCCHHHEEECCCCCCCCEEEEEEEECCCE
GIVMLANKNFPVPERVKAAFRILAALDGAPGRADTP
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKRIPVARIATIAMACSLFAANASAADSVGQRQIERAVNDAIRPLMAAHGVPGMAVAVTA
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GGKRYVFNYGVAAKEGRRKVDGDTLFEIGSVSKTFTATLASYGQARGTLSLADPAGKYLP
CCCEEEEECCCCCCCCCCCCCCCHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHH
ALAGSSLGATSLLDLGTYAAGGLPLQFPDAVTDTRTMVDYFRGWRPRYAAGSHRQYSNPS
HHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
IGLFGYLAASSMGQPFDDLMEKTLFPALGLAHTYIRVPKARMGDYAYGYSKDGKPVRVTP
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECC
GVLDAEAYGVKTTAADMIRFVEANIDSAGLDDKLRRAIAGTHTGYFKVGDMVQGLGWEMY
CCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHCCCCEEE
AWPTRVDSVLAGSSPQVVLEANQVSRLEPPLSSPADVLVNKTGSTNGFGAYVVFVPAKRI
ECCHHHHHHHCCCCCCEEEECCHHHHCCCCCCCCHHHEEECCCCCCCCEEEEEEEECCCE
GIVMLANKNFPVPERVKAAFRILAALDGAPGRADTP
EEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA