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The map label for this gene is pap [H]

Identifier: 116694998

GI number: 116694998

Start: 1188232

End: 1189257

Strand: Direct

Name: pap [H]

Synonym: H16_B1053

Alternate gene names: 116694998

Gene position: 1188232-1189257 (Clockwise)

Preceding gene: 116694993

Following gene: 116694999

Centisome position: 40.8

GC content: 72.71

Gene sequence:

>1026_bases
GTGAATATCGTTGTGCAGCGGCGCCTGGCTGCCGCCCGACTGCCGCATCCCTTCAAGGCAACATCCATGCCCGACGCATC
AACGATTTCTGCCGGCTTTTCCGACGCGGCCACCACCTTCCACCTGCGTACGCCCGATGCCCAGCGCGTGCATGTGCGGC
TGGCCGGCGCCGCGGACGGCGAGCCGTGGCTGGTGCTGCATGGCGGGCCGGGCAGCGGCTGCTCTGCCGCCATGGCGCAG
TGGTTCGACCCGCGGCGGCACCGCGTGGTGATGCCGGACCAGCGCGGCGCCGGCCGCTCCAGGCCGGCCGGCTGCCTGCG
CCGCAATACCGTGGGCGCGCTGCTGGCCGACCTGGAGCAGCTGCGCCGCGCGCTGGGCATCGAGCGCTGGGGCGTGGTGG
GCGGATCATGGGGTGCAGCACTTGCCCTGGCGTACGCGGCGCAATGCCCGCACGCCGTGGCGGCGCTGGTCCTGCGCGGC
TCCTTCCTGACCGGCCGCGACGATGTGCTCGCGCTGTTTTCACCGCGCCATGGGGGCCGCCGCATGCTGCATTGCGTCAA
GGCATGGGGCGAGCGCTTGCCCGATGCGCGCGCGCGGCTGCTCACTGTGTCACGGCTGTTGCAAAGTGGTACGCCTGTTC
AAAAACGGGACACTGCCGCGGCGTGGCAGGCGAGCGAACAGGCGTGGTTGGGTCTTTCCCCTGCGTCGCATTCGCGCCGG
CAGCGGCGGCCTGAGCGCATGGCCGCGGTGAACAAATACCGGATCCAGGCGCACTACCTGCGCAACCGGGCCGGACTGGG
CAAGCCGGCCCTGCTCAGCGCGGCGCGGGTCATCGGCGCGCATGGCCTGCCGGTGACGCTGCTGCATGGCCGCGCCGACA
AGGTCTGCCGTCCCGCCAACGCGCTGCGCCTGCAGGCCGCCATGCCGGGCGCAAGGCTGGCCTGGGTGGACGGCGGACAC
CTGGCGGCAGGGGCCATGCGCGACGCCCTGGTGGCCGCGATCCGCGCCGCGGGCTGGCAGCGGTGA

Upstream 100 bases:

>100_bases
CAGCGGTTGGCGATGTACATCGTGATTTCAAAGCCAAGCCGCAGCTCGGTGTAGGCGGGGGTGGTCCAGCGCATGTCTCT
CTCCTTGGGTGGCATGGTTA

Downstream 100 bases:

>100_bases
TGCCCACGACGCGGCGCGGCTTTCTTGGCGCCACGCTTGCGCTGGCCATGAACGGCTGGCGCCCGGCGGCCGCTGCCGGC
ACGCGGGTCACGCTGGAGCG

Product: prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNIVVQRRLAAARLPHPFKATSMPDASTISAGFSDAATTFHLRTPDAQRVHVRLAGAADGEPWLVLHGGPGSGCSAAMAQ
WFDPRRHRVVMPDQRGAGRSRPAGCLRRNTVGALLADLEQLRRALGIERWGVVGGSWGAALALAYAAQCPHAVAALVLRG
SFLTGRDDVLALFSPRHGGRRMLHCVKAWGERLPDARARLLTVSRLLQSGTPVQKRDTAAAWQASEQAWLGLSPASHSRR
QRRPERMAAVNKYRIQAHYLRNRAGLGKPALLSAARVIGAHGLPVTLLHGRADKVCRPANALRLQAAMPGARLAWVDGGH
LAAGAMRDALVAAIRAAGWQR

Sequences:

>Translated_341_residues
MNIVVQRRLAAARLPHPFKATSMPDASTISAGFSDAATTFHLRTPDAQRVHVRLAGAADGEPWLVLHGGPGSGCSAAMAQ
WFDPRRHRVVMPDQRGAGRSRPAGCLRRNTVGALLADLEQLRRALGIERWGVVGGSWGAALALAYAAQCPHAVAALVLRG
SFLTGRDDVLALFSPRHGGRRMLHCVKAWGERLPDARARLLTVSRLLQSGTPVQKRDTAAAWQASEQAWLGLSPASHSRR
QRRPERMAAVNKYRIQAHYLRNRAGLGKPALLSAARVIGAHGLPVTLLHGRADKVCRPANALRLQAAMPGARLAWVDGGH
LAAGAMRDALVAAIRAAGWQR
>Mature_341_residues
MNIVVQRRLAAARLPHPFKATSMPDASTISAGFSDAATTFHLRTPDAQRVHVRLAGAADGEPWLVLHGGPGSGCSAAMAQ
WFDPRRHRVVMPDQRGAGRSRPAGCLRRNTVGALLADLEQLRRALGIERWGVVGGSWGAALALAYAAQCPHAVAALVLRG
SFLTGRDDVLALFSPRHGGRRMLHCVKAWGERLPDARARLLTVSRLLQSGTPVQKRDTAAAWQASEQAWLGLSPASHSRR
QRRPERMAAVNKYRIQAHYLRNRAGLGKPALLSAARVIGAHGLPVTLLHGRADKVCRPANALRLQAAMPGARLAWVDGGH
LAAGAMRDALVAAIRAAGWQR

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36651; Mature: 36651

Theoretical pI: Translated: 12.20; Mature: 12.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVVQRRLAAARLPHPFKATSMPDASTISAGFSDAATTFHLRTPDAQRVHVRLAGAADG
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCC
EPWLVLHGGPGSGCSAAMAQWFDPRRHRVVMPDQRGAGRSRPAGCLRRNTVGALLADLEQ
CCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LRRALGIERWGVVGGSWGAALALAYAAQCPHAVAALVLRGSFLTGRDDVLALFSPRHGGR
HHHHHCCHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
RMLHCVKAWGERLPDARARLLTVSRLLQSGTPVQKRDTAAAWQASEQAWLGLSPASHSRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHCHHHHHHCCCCCEEECCCCHHHHH
QRRPERMAAVNKYRIQAHYLRNRAGLGKPALLSAARVIGAHGLPVTLLHGRADKVCRPAN
HCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCH
ALRLQAAMPGARLAWVDGGHLAAGAMRDALVAAIRAAGWQR
HEEEHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIVVQRRLAAARLPHPFKATSMPDASTISAGFSDAATTFHLRTPDAQRVHVRLAGAADG
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEEEECCCC
EPWLVLHGGPGSGCSAAMAQWFDPRRHRVVMPDQRGAGRSRPAGCLRRNTVGALLADLEQ
CCEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LRRALGIERWGVVGGSWGAALALAYAAQCPHAVAALVLRGSFLTGRDDVLALFSPRHGGR
HHHHHCCHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
RMLHCVKAWGERLPDARARLLTVSRLLQSGTPVQKRDTAAAWQASEQAWLGLSPASHSRR
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHCHHHHHHCCCCCEEECCCCHHHHH
QRRPERMAAVNKYRIQAHYLRNRAGLGKPALLSAARVIGAHGLPVTLLHGRADKVCRPAN
HCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHCCCCH
ALRLQAAMPGARLAWVDGGHLAAGAMRDALVAAIRAAGWQR
HEEEHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]