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The map label for this gene is hmp [H]

Identifier: 116694896

GI number: 116694896

Start: 1074180

End: 1074596

Strand: Direct

Name: hmp [H]

Synonym: H16_B0951

Alternate gene names: 116694896

Gene position: 1074180-1074596 (Clockwise)

Preceding gene: 116694895

Following gene: 116694897

Centisome position: 36.88

GC content: 63.31

Gene sequence:

>417_bases
ATGACACCGCAAGAGATCACCCTGGTACAAAGCTCCTGGCAGAAGGTGGTGCCGATCAAGGAAAAGGCCGCCGAGCTGTT
CTACGGCAAGCTGTTCGAAATGGATCCCTCGCTGAGGCCACTGTTCAAGGGCGACACCGTCGAACAGGGGCGCAAGCTGA
TGGCGATGATCAATGCCGTCGTCACGAAACTGGACCAGCTCGACGACATCGTTCCCGCTGTACAGGAACTCGGCCGGCGC
CACGTCGCCTATGGCGTCAAGGACGAGGACTACGACACCGTGGCCGGCGCCCTGCTGTGGACACTGGGTGCCGGCCTCGG
GGACGCCTTTACCGATGAGGTGAAGGGCGCCTGGACCAGCGCCTACGTGATCCTGGCCGGGGCCATGAAAGACGCCGCCG
CGACCGCCTGGGACTGA

Upstream 100 bases:

>100_bases
GCATCCCTGTCAGCAATTGAGCCAGCGAAAAGCTGAGCGATGACGACGTGAAGGCAGTAGCGGATTACATGATCGCAATT
GTCAAGTAAAGGAATATTCC

Downstream 100 bases:

>100_bases
CTCAGGAGGAATGAGGCCATGCTGGAAGCAGTGTCACTGACCGCCGCGCGCGGCGACCGGCCGATTTTCATCAGGCTGGG
GCTGCGCGTGGAGCCCGGGC

Product: hemoglobin-like protein (Hmp)

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTPQEITLVQSSWQKVVPIKEKAAELFYGKLFEMDPSLRPLFKGDTVEQGRKLMAMINAVVTKLDQLDDIVPAVQELGRR
HVAYGVKDEDYDTVAGALLWTLGAGLGDAFTDEVKGAWTSAYVILAGAMKDAAATAWD

Sequences:

>Translated_138_residues
MTPQEITLVQSSWQKVVPIKEKAAELFYGKLFEMDPSLRPLFKGDTVEQGRKLMAMINAVVTKLDQLDDIVPAVQELGRR
HVAYGVKDEDYDTVAGALLWTLGAGLGDAFTDEVKGAWTSAYVILAGAMKDAAATAWD
>Mature_137_residues
TPQEITLVQSSWQKVVPIKEKAAELFYGKLFEMDPSLRPLFKGDTVEQGRKLMAMINAVVTKLDQLDDIVPAVQELGRRH
VAYGVKDEDYDTVAGALLWTLGAGLGDAFTDEVKGAWTSAYVILAGAMKDAAATAWD

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1017

COG function: function code C; Hemoglobin-like flavoprotein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI10864065, Length=153, Percent_Identity=30.718954248366, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788903, Length=138, Percent_Identity=26.8115942028986, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 15090; Mature: 14959

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQEITLVQSSWQKVVPIKEKAAELFYGKLFEMDPSLRPLFKGDTVEQGRKLMAMINAV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTKLDQLDDIVPAVQELGRRHVAYGVKDEDYDTVAGALLWTLGAGLGDAFTDEVKGAWTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
AYVILAGAMKDAAATAWD
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPQEITLVQSSWQKVVPIKEKAAELFYGKLFEMDPSLRPLFKGDTVEQGRKLMAMINAV
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
VTKLDQLDDIVPAVQELGRRHVAYGVKDEDYDTVAGALLWTLGAGLGDAFTDEVKGAWTS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHH
AYVILAGAMKDAAATAWD
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]