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The map label for this gene is pepP [H]

Identifier: 116694868

GI number: 116694868

Start: 1043221

End: 1044411

Strand: Direct

Name: pepP [H]

Synonym: H16_B0923

Alternate gene names: 116694868

Gene position: 1043221-1044411 (Clockwise)

Preceding gene: 116694867

Following gene: 116694874

Centisome position: 35.82

GC content: 66.16

Gene sequence:

>1191_bases
ATGGCACATCTCACCAAGGCCGTACAAGGCTATCGCCTGGCGGCGATGCACAGGCTGATGGACAAGCTGCGCGTCGATGC
GCTGGTGTTCGGCACGCCTGACTTTTTCCAGTACGCGACCAATTTCCAGCTCGATGTCTGGCCGTGGGAGCGCCCGGTGT
TCGTGGTGGTGCCGCGCAATGGCGACACCTTCGCGGTCATGAACGAGCTGTCGACCAACCATATGCGCTTTGCGACCGGG
AAGGGCTCGGTCTGGCTTGCCGATGTCACCTACTACGCCGAGCATCCCCGTGTCTCGAATCGCCTGCCGCTGCCTGCGCA
GCTGCCGGAAGTGGTTGCCGCGCTGCTGGGGGCCAGGGGGCTCGGCATGTCGCGGATTGCGGTCGACGTCCAGCATCCGA
TCCTGGCCGGTGCGCAGCGCTGCCTGCCTGAACTCACGCTGCGGCCCGCCATGGCGGAGATGCGCAGCCTGCGCTGGGTC
AAGCATGCGGAGGAGCTGCAGGTCATGCGCGAGCTAGGTGCGCTGACAGACTGGGTGCAGGATCGCTACCGCGAGAACTT
CCGGCCAGGCCGGCTGGTGCAGGAGCTTGACCACGCCATGGCGGCGCTGATGTCGGAGGAGGCGGCGCGGCGCTTTCCGG
GCGAGGACTTCGACATCCTCAAATGCTGGACGCTGACCGGGCCAGCTTCGGCATCGCCGCATGGCGATGGCGCCGGATGC
GGCGCACGGATTTCCGCCGGCGACACCATCGTCAACCTGGTGCTGCCGCGCCTGAACGGGCTGTATGTCGAGAATGAGCG
CACCTGGTTTTGCGGCCGGCCCGGCGACGAGCAGGCGCGGTTCTACCAGGTTGCGGCAAAGGCCACCGACGCTGCCGTTG
CCGCGGCGGTGGTCGGCAAGCGCGTCTGCGACATGGATGCGGCCGCGCAGGCTGTGATCGAGCAGGCCGGCTGCGGGGAC
TATGTCTTTCATCGCACCGGCCACGCGGTCGGTCTGATGCTGCATGAATACCCGGAGGACATGGCCTTCAATACCCGCCC
GCTGCTTGCGGGAGAGGTGTATTCGGCGGAGCCGGGCCTCTATGTCTACGGCCTTGGCGGCTTCCGGCTGGACGATACCG
TGGTGGTTGGCGACCAGCCGGAGGTCATCATCAAGACGCCGAAGACGCTGGAATACGCAACCGTGGACTAG

Upstream 100 bases:

>100_bases
AGGGGCCGCCGTCCGAGGTGGAGCGCTATATGAAGCGCGACGCCGATACCTGGGGCCCGATCATCCGCAACCTTGCCATT
TCTCTCTGAGGACCGCTGCC

Downstream 100 bases:

>100_bases
GCGCCCGCAGCGTAGCTCAGTCGAGTGTCACCCCCGTATCCGCCGTCAGCTTGAGCACCACCGGCAGGTACGCCTTGTAC
GCCGCCTCTGCCTGTGCCGG

Product: aminopeptidase P ( Xaa-Pro aminopeptidase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAHLTKAVQGYRLAAMHRLMDKLRVDALVFGTPDFFQYATNFQLDVWPWERPVFVVVPRNGDTFAVMNELSTNHMRFATG
KGSVWLADVTYYAEHPRVSNRLPLPAQLPEVVAALLGARGLGMSRIAVDVQHPILAGAQRCLPELTLRPAMAEMRSLRWV
KHAEELQVMRELGALTDWVQDRYRENFRPGRLVQELDHAMAALMSEEAARRFPGEDFDILKCWTLTGPASASPHGDGAGC
GARISAGDTIVNLVLPRLNGLYVENERTWFCGRPGDEQARFYQVAAKATDAAVAAAVVGKRVCDMDAAAQAVIEQAGCGD
YVFHRTGHAVGLMLHEYPEDMAFNTRPLLAGEVYSAEPGLYVYGLGGFRLDDTVVVGDQPEVIIKTPKTLEYATVD

Sequences:

>Translated_396_residues
MAHLTKAVQGYRLAAMHRLMDKLRVDALVFGTPDFFQYATNFQLDVWPWERPVFVVVPRNGDTFAVMNELSTNHMRFATG
KGSVWLADVTYYAEHPRVSNRLPLPAQLPEVVAALLGARGLGMSRIAVDVQHPILAGAQRCLPELTLRPAMAEMRSLRWV
KHAEELQVMRELGALTDWVQDRYRENFRPGRLVQELDHAMAALMSEEAARRFPGEDFDILKCWTLTGPASASPHGDGAGC
GARISAGDTIVNLVLPRLNGLYVENERTWFCGRPGDEQARFYQVAAKATDAAVAAAVVGKRVCDMDAAAQAVIEQAGCGD
YVFHRTGHAVGLMLHEYPEDMAFNTRPLLAGEVYSAEPGLYVYGLGGFRLDDTVVVGDQPEVIIKTPKTLEYATVD
>Mature_395_residues
AHLTKAVQGYRLAAMHRLMDKLRVDALVFGTPDFFQYATNFQLDVWPWERPVFVVVPRNGDTFAVMNELSTNHMRFATGK
GSVWLADVTYYAEHPRVSNRLPLPAQLPEVVAALLGARGLGMSRIAVDVQHPILAGAQRCLPELTLRPAMAEMRSLRWVK
HAEELQVMRELGALTDWVQDRYRENFRPGRLVQELDHAMAALMSEEAARRFPGEDFDILKCWTLTGPASASPHGDGAGCG
ARISAGDTIVNLVLPRLNGLYVENERTWFCGRPGDEQARFYQVAAKATDAAVAAAVVGKRVCDMDAAAQAVIEQAGCGDY
VFHRTGHAVGLMLHEYPEDMAFNTRPLLAGEVYSAEPGLYVYGLGGFRLDDTVVVGDQPEVIIKTPKTLEYATVD

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=260, Percent_Identity=31.1538461538462, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 43745; Mature: 43613

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLTKAVQGYRLAAMHRLMDKLRVDALVFGTPDFFQYATNFQLDVWPWERPVFVVVPRN
CCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHCCCEEEECCCCCCEEEEEECC
GDTFAVMNELSTNHMRFATGKGSVWLADVTYYAEHPRVSNRLPLPAQLPEVVAALLGARG
CCEEEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
LGMSRIAVDVQHPILAGAQRCLPELTLRPAMAEMRSLRWVKHAEELQVMRELGALTDWVQ
CCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRYRENFRPGRLVQELDHAMAALMSEEAARRFPGEDFDILKCWTLTGPASASPHGDGAGC
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
GARISAGDTIVNLVLPRLNGLYVENERTWFCGRPGDEQARFYQVAAKATDAAVAAAVVGK
CCEECCCHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RVCDMDAAAQAVIEQAGCGDYVFHRTGHAVGLMLHEYPEDMAFNTRPLLAGEVYSAEPGL
HHHCHHHHHHHHHHHCCCCCCHHHCCCCEEEHHHHHCCHHCCCCCCCCEECCEECCCCCE
YVYGLGGFRLDDTVVVGDQPEVIIKTPKTLEYATVD
EEEECCCEEECCEEEECCCCCEEEECCCCCEEEECC
>Mature Secondary Structure 
AHLTKAVQGYRLAAMHRLMDKLRVDALVFGTPDFFQYATNFQLDVWPWERPVFVVVPRN
CCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHCCCEEEECCCCCCEEEEEECC
GDTFAVMNELSTNHMRFATGKGSVWLADVTYYAEHPRVSNRLPLPAQLPEVVAALLGARG
CCEEEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCC
LGMSRIAVDVQHPILAGAQRCLPELTLRPAMAEMRSLRWVKHAEELQVMRELGALTDWVQ
CCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRYRENFRPGRLVQELDHAMAALMSEEAARRFPGEDFDILKCWTLTGPASASPHGDGAGC
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCC
GARISAGDTIVNLVLPRLNGLYVENERTWFCGRPGDEQARFYQVAAKATDAAVAAAVVGK
CCEECCCHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RVCDMDAAAQAVIEQAGCGDYVFHRTGHAVGLMLHEYPEDMAFNTRPLLAGEVYSAEPGL
HHHCHHHHHHHHHHHCCCCCCHHHCCCCEEEHHHHHCCHHCCCCCCCCEECCEECCCCCE
YVYGLGGFRLDDTVVVGDQPEVIIKTPKTLEYATVD
EEEECCCEEECCEEEECCCCCEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]