Click here to switch to the map view.

The map label for this gene is pknK [H]

Identifier: 116694705

GI number: 116694705

Start: 851127

End: 853889

Strand: Direct

Name: pknK [H]

Synonym: H16_B0754

Alternate gene names: 116694705

Gene position: 851127-853889 (Clockwise)

Preceding gene: 116694704

Following gene: 116694708

Centisome position: 29.22

GC content: 70.83

Gene sequence:

>2763_bases
ATGGCAAGTATCGAGGAGACCGGACGGCGCGCGCCGCCGCCCGCCGGCGCCGCATCGCTGGCGGCCAAACTGCGTCCGCC
GCTGCTGACCCCGTTCCAGGTCGAGCGCGCGGCGATCTGCGAGACCGTGTGCGCGGCCGGTTTCGTCAAGCTTGTGCTGG
TGCGTGCACCGGCGGGCTTCGGCAAGACCACGGCCATGCTCCAGTGTCGCGCGCGCCTGGAGGCCGCGGGCGGGCGCACC
GCCTGGCTGACGCTGGATCGGTCGGACAATGATGCCTCGCGCTTTCTGGGGTCGGTCGAAGCTGCCATCGCGCAGGGCCT
GGGCGGCGGCGGCCCCGGCCGGTCCGCGCACGCGACGCTGGCACAGGATCCCGGCGAGCAGGCGCTCGCGCTGATCGACC
GCCTGGCCAGCCATAACGGCGCCTTCACGCTGTTCCTCGATGATTTCGAAGCGATCCAGAACGCCGCCGTGACCGGGCTG
GTCTGGCAACTGGTGGAAAGCCTGCCGCCCGGCTGCCGCGTGGTGATCGGCACGCGCTGGGTTCCGGAATCCGGCCTGGG
CCGCCTGCGCGCGCGCGGCGAGCTGCTTGAGATCGAACCCGCGCAGCTGCGTTTTTCCGCCAGCGAAACTGCATCCTTCC
TGCGCCGTGCGCGCGGGCTGAAGCTGGAGCAGGCGGCCATCAGCGTGCTGCACCGGCGTACCGAGGGCTGGGCCACGGCA
TTGTGGCTGGCGTCAGTCGCGCTGGAGCGGCGCAGCCAGCCAGAGGGTTTTATCGCCGGCTTCTCCGGCTCCAACGCGGC
GATTGCCGACTACCTGGTCGAAGACGTATTCCTGCACCTGCCCGAGGCGGTGCGCGACTTCCTGCTGCGCACCTCGATCC
TGGACCAGTTGTGCGGACCGCTGTGCGACGCCGTGTGCAAGCCCGCGACAGCTGGCAGCAGCGACGAGATCCTGGCCTGG
CTGGAGCGCGCCAACCTGTTCCTGCTGCCGCTGGAGAGCGAACGCTATGGCGAGCGTGGCTCCGGTGCGGCATCGGAGCA
GTGGTACCGCTATCACAGCCTCTTTTCCGGCTTCCTGCGCGGCCAGCTGGCGCAGGCCATGCCTGACGCCGTGCCGCAGC
TGCACCTGTCGGCATCGCGCTGGTATGAGTCGCAGGGGCGCCCGGTGCCCGCCATCGAGCATGCCTTCGCGGCCGGTGCG
CTGGCGCGCGCGCTGCCGTTGCTGGACGGCGCCGCGGACGACCTGCTGGCGCAGGGCCGCATGCGCCTGCTGACGCGCTG
GCTGGAGGCGGTGCCGGCGGAAGAACTGGCGCGCTGGCCCAAGCTGCAGATCGCGCGCGTGTGGGCGGTGTCGTTCACGC
GCGGCCCGGCCGAAGCCATCGCCCTGCTGCAGCAGATCCCCACCGAGGGCGCGGCCGGCGACCTGCTGGCGCATATCCGC
GCGCTGCGCCACATGCTGCTGAACATGATGGACCGCTTCGACGATGCGCGCGCCTTCGCCCGCAATGAGCTGCCGCCGTT
GCCGATGGGCTATGCCTTCCCCGATGCGATCCTGGGCACGTCGATGGCACGCCTGGCTGCGGTCGCCGGCGACTACCCGG
AGGCGCGCCGGCTGCTGCAGGTGGCACGGCACGCGGTGCGAGGCTCGGACAGCAATTTCAACAAGATTTTCTCGGAATCG
GTCGAAGGGCTGATCGACCTGCGCCAGGGGCGGCTGCAGCAGGCGCTGGCGCGGTTTCGCATCGCCGCCAGCACGATGCT
GCCGAACCGCTTCGGGCCCACCAACGGCAATGCCATGGCCGGCATCCTGCTGGCCGAAGGCCTGTACGAGAGCGGTGATT
CCGAGCGCGCCAGCCGATTGCTCAACGTCTACCTGCCGCTGTCGCGCGACCTCGGGCTGCCTGACCAGATCATCACCGGG
CACACGGTGCTGGCCCGCATTGCCTTCGAGCGCGGCGAAGCCGACCAGGCGCATGAATGGCTGGCGCAACTGGAAGCGCT
GGGGCACCACCGCGGGCTGACGCGGCTGGTGATGGCGGCAATGCTGGAGCGCGCACGGCTGGCACTGCGCCAGGGCAATG
TTCACGCGGCGCAGGAGGCGATCGAACGCGCCGCCGATCCGGCGCTGTGGCGCACGCGGCCCGGGGTCAGCTCCTTTGCC
AGCGATGTCGAGGACATCACCCTTGGCCGGCTGCGGCTGGACCTGTATGCGCGCCCGGGCACGCCGGTGCGCGAGGTCAT
CGAGCGCGAGCTGGCGGCTGCCGCCGGCAACCAGCTGATGCGCCGCGCGCTCAAGCTGCGCATCCTGCTGGCGCAGGCGT
GCCAGCGCACCGGCGACGGCGCGCACGCGCTGGTGGTGATGGGCGAGGCGCTGCGTTTCGGCGCTGCCGAAGGCTTTGTC
CGCATCTTTGCCGACGAGGGCGACGATGTGCGCAGGCTGGTGGCCGATGCCTGCTCGCGCCAGTCGGCCAGCCTGCCTGC
CCCCTATGTGGAAAGGCTGCTGCAGGCCTGCGGCCAGGCCGGGAGCGAGCAGGCCGCCGGTACCGGCCGGCCGGCGCCGG
CGGCGCTGGTGGAGCCGCTGACGCCCAAGGAGCAGAAGGTGCTGCAACTGCTGGCCGAGGGCTATTCCAATGTGGCCATG
GCCGAGCGCCTGTTCGTGTCCGAAACCACGGTGCGCACGCACCTGCGCAATATCAGCGCCAAGCTGCACGCCAGCAACCG
CACCCAGGCGGTGGCCATTGCACGCCAGCTCGGGCTGCTCTGA

Upstream 100 bases:

>100_bases
GTTACATCACAGCCACGGCCCGCCTGCCTGCATCCGCAGCGCGGGCGGGCGCATCGCGCGGCCTGCAACGGCAGCGATGT
GCGGGAGACGACAACAGCCA

Downstream 100 bases:

>100_bases
GGCCGCGCGCGCAGGTCAGCCCGCGCGCGCTTGCGGCTCAGATGCCCATGAACTCCGTGAATTCCTCCAGCGGTGCGCGC
ACGGAACGCAGCTGGTTGGC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protein kinase K [H]

Number of amino acids: Translated: 920; Mature: 919

Protein sequence:

>920_residues
MASIEETGRRAPPPAGAASLAAKLRPPLLTPFQVERAAICETVCAAGFVKLVLVRAPAGFGKTTAMLQCRARLEAAGGRT
AWLTLDRSDNDASRFLGSVEAAIAQGLGGGGPGRSAHATLAQDPGEQALALIDRLASHNGAFTLFLDDFEAIQNAAVTGL
VWQLVESLPPGCRVVIGTRWVPESGLGRLRARGELLEIEPAQLRFSASETASFLRRARGLKLEQAAISVLHRRTEGWATA
LWLASVALERRSQPEGFIAGFSGSNAAIADYLVEDVFLHLPEAVRDFLLRTSILDQLCGPLCDAVCKPATAGSSDEILAW
LERANLFLLPLESERYGERGSGAASEQWYRYHSLFSGFLRGQLAQAMPDAVPQLHLSASRWYESQGRPVPAIEHAFAAGA
LARALPLLDGAADDLLAQGRMRLLTRWLEAVPAEELARWPKLQIARVWAVSFTRGPAEAIALLQQIPTEGAAGDLLAHIR
ALRHMLLNMMDRFDDARAFARNELPPLPMGYAFPDAILGTSMARLAAVAGDYPEARRLLQVARHAVRGSDSNFNKIFSES
VEGLIDLRQGRLQQALARFRIAASTMLPNRFGPTNGNAMAGILLAEGLYESGDSERASRLLNVYLPLSRDLGLPDQIITG
HTVLARIAFERGEADQAHEWLAQLEALGHHRGLTRLVMAAMLERARLALRQGNVHAAQEAIERAADPALWRTRPGVSSFA
SDVEDITLGRLRLDLYARPGTPVREVIERELAAAAGNQLMRRALKLRILLAQACQRTGDGAHALVVMGEALRFGAAEGFV
RIFADEGDDVRRLVADACSRQSASLPAPYVERLLQACGQAGSEQAAGTGRPAPAALVEPLTPKEQKVLQLLAEGYSNVAM
AERLFVSETTVRTHLRNISAKLHASNRTQAVAIARQLGLL

Sequences:

>Translated_920_residues
MASIEETGRRAPPPAGAASLAAKLRPPLLTPFQVERAAICETVCAAGFVKLVLVRAPAGFGKTTAMLQCRARLEAAGGRT
AWLTLDRSDNDASRFLGSVEAAIAQGLGGGGPGRSAHATLAQDPGEQALALIDRLASHNGAFTLFLDDFEAIQNAAVTGL
VWQLVESLPPGCRVVIGTRWVPESGLGRLRARGELLEIEPAQLRFSASETASFLRRARGLKLEQAAISVLHRRTEGWATA
LWLASVALERRSQPEGFIAGFSGSNAAIADYLVEDVFLHLPEAVRDFLLRTSILDQLCGPLCDAVCKPATAGSSDEILAW
LERANLFLLPLESERYGERGSGAASEQWYRYHSLFSGFLRGQLAQAMPDAVPQLHLSASRWYESQGRPVPAIEHAFAAGA
LARALPLLDGAADDLLAQGRMRLLTRWLEAVPAEELARWPKLQIARVWAVSFTRGPAEAIALLQQIPTEGAAGDLLAHIR
ALRHMLLNMMDRFDDARAFARNELPPLPMGYAFPDAILGTSMARLAAVAGDYPEARRLLQVARHAVRGSDSNFNKIFSES
VEGLIDLRQGRLQQALARFRIAASTMLPNRFGPTNGNAMAGILLAEGLYESGDSERASRLLNVYLPLSRDLGLPDQIITG
HTVLARIAFERGEADQAHEWLAQLEALGHHRGLTRLVMAAMLERARLALRQGNVHAAQEAIERAADPALWRTRPGVSSFA
SDVEDITLGRLRLDLYARPGTPVREVIERELAAAAGNQLMRRALKLRILLAQACQRTGDGAHALVVMGEALRFGAAEGFV
RIFADEGDDVRRLVADACSRQSASLPAPYVERLLQACGQAGSEQAAGTGRPAPAALVEPLTPKEQKVLQLLAEGYSNVAM
AERLFVSETTVRTHLRNISAKLHASNRTQAVAIARQLGLL
>Mature_919_residues
ASIEETGRRAPPPAGAASLAAKLRPPLLTPFQVERAAICETVCAAGFVKLVLVRAPAGFGKTTAMLQCRARLEAAGGRTA
WLTLDRSDNDASRFLGSVEAAIAQGLGGGGPGRSAHATLAQDPGEQALALIDRLASHNGAFTLFLDDFEAIQNAAVTGLV
WQLVESLPPGCRVVIGTRWVPESGLGRLRARGELLEIEPAQLRFSASETASFLRRARGLKLEQAAISVLHRRTEGWATAL
WLASVALERRSQPEGFIAGFSGSNAAIADYLVEDVFLHLPEAVRDFLLRTSILDQLCGPLCDAVCKPATAGSSDEILAWL
ERANLFLLPLESERYGERGSGAASEQWYRYHSLFSGFLRGQLAQAMPDAVPQLHLSASRWYESQGRPVPAIEHAFAAGAL
ARALPLLDGAADDLLAQGRMRLLTRWLEAVPAEELARWPKLQIARVWAVSFTRGPAEAIALLQQIPTEGAAGDLLAHIRA
LRHMLLNMMDRFDDARAFARNELPPLPMGYAFPDAILGTSMARLAAVAGDYPEARRLLQVARHAVRGSDSNFNKIFSESV
EGLIDLRQGRLQQALARFRIAASTMLPNRFGPTNGNAMAGILLAEGLYESGDSERASRLLNVYLPLSRDLGLPDQIITGH
TVLARIAFERGEADQAHEWLAQLEALGHHRGLTRLVMAAMLERARLALRQGNVHAAQEAIERAADPALWRTRPGVSSFAS
DVEDITLGRLRLDLYARPGTPVREVIERELAAAAGNQLMRRALKLRILLAQACQRTGDGAHALVVMGEALRFGAAEGFVR
IFADEGDDVRRLVADACSRQSASLPAPYVERLLQACGQAGSEQAAGTGRPAPAALVEPLTPKEQKVLQLLAEGYSNVAMA
ERLFVSETTVRTHLRNISAKLHASNRTQAVAIARQLGLL

Specific function: Modulates the activity of transcription regulator virS via phosphorylation [H]

COG id: COG2909

COG function: function code K; ATP-dependent transcriptional regulator

Gene ontology:

Cell location: Cell membrane. Note=Probably attached to cell membrane through interactions mediated by its C- terminal region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Escherichia coli, GI2367223, Length=931, Percent_Identity=25.9935553168636, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016236
- InterPro:   IPR011990 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 99421; Mature: 99290

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50043 HTH_LUXR_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIEETGRRAPPPAGAASLAAKLRPPLLTPFQVERAAICETVCAAGFVKLVLVRAPAGF
CCCCHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GKTTAMLQCRARLEAAGGRTAWLTLDRSDNDASRFLGSVEAAIAQGLGGGGPGRSAHATL
CHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AQDPGEQALALIDRLASHNGAFTLFLDDFEAIQNAAVTGLVWQLVESLPPGCRVVIGTRW
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
VPESGLGRLRARGELLEIEPAQLRFSASETASFLRRARGLKLEQAAISVLHRRTEGWATA
CCCCCHHHHHHCCCEEECCHHHHEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LWLASVALERRSQPEGFIAGFSGSNAAIADYLVEDVFLHLPEAVRDFLLRTSILDQLCGP
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LCDAVCKPATAGSSDEILAWLERANLFLLPLESERYGERGSGAASEQWYRYHSLFSGFLR
HHHHHCCCCCCCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
GQLAQAMPDAVPQLHLSASRWYESQGRPVPAIEHAFAAGALARALPLLDGAADDLLAQGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MRLLTRWLEAVPAEELARWPKLQIARVWAVSFTRGPAEAIALLQQIPTEGAAGDLLAHIR
HHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
ALRHMLLNMMDRFDDARAFARNELPPLPMGYAFPDAILGTSMARLAAVAGDYPEARRLLQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VARHAVRGSDSNFNKIFSESVEGLIDLRQGRLQQALARFRIAASTMLPNRFGPTNGNAMA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GILLAEGLYESGDSERASRLLNVYLPLSRDLGLPDQIITGHTVLARIAFERGEADQAHEW
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
LAQLEALGHHRGLTRLVMAAMLERARLALRQGNVHAAQEAIERAADPALWRTRPGVSSFA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCHHHHH
SDVEDITLGRLRLDLYARPGTPVREVIERELAAAAGNQLMRRALKLRILLAQACQRTGDG
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHALVVMGEALRFGAAEGFVRIFADEGDDVRRLVADACSRQSASLPAPYVERLLQACGQA
CEEEEEEHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
GSEQAAGTGRPAPAALVEPLTPKEQKVLQLLAEGYSNVAMAERLFVSETTVRTHLRNISA
CCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLHASNRTQAVAIARQLGLL
HHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ASIEETGRRAPPPAGAASLAAKLRPPLLTPFQVERAAICETVCAAGFVKLVLVRAPAGF
CCCHHCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GKTTAMLQCRARLEAAGGRTAWLTLDRSDNDASRFLGSVEAAIAQGLGGGGPGRSAHATL
CHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AQDPGEQALALIDRLASHNGAFTLFLDDFEAIQNAAVTGLVWQLVESLPPGCRVVIGTRW
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
VPESGLGRLRARGELLEIEPAQLRFSASETASFLRRARGLKLEQAAISVLHRRTEGWATA
CCCCCHHHHHHCCCEEECCHHHHEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LWLASVALERRSQPEGFIAGFSGSNAAIADYLVEDVFLHLPEAVRDFLLRTSILDQLCGP
HHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LCDAVCKPATAGSSDEILAWLERANLFLLPLESERYGERGSGAASEQWYRYHSLFSGFLR
HHHHHCCCCCCCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHHH
GQLAQAMPDAVPQLHLSASRWYESQGRPVPAIEHAFAAGALARALPLLDGAADDLLAQGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MRLLTRWLEAVPAEELARWPKLQIARVWAVSFTRGPAEAIALLQQIPTEGAAGDLLAHIR
HHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
ALRHMLLNMMDRFDDARAFARNELPPLPMGYAFPDAILGTSMARLAAVAGDYPEARRLLQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
VARHAVRGSDSNFNKIFSESVEGLIDLRQGRLQQALARFRIAASTMLPNRFGPTNGNAMA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GILLAEGLYESGDSERASRLLNVYLPLSRDLGLPDQIITGHTVLARIAFERGEADQAHEW
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
LAQLEALGHHRGLTRLVMAAMLERARLALRQGNVHAAQEAIERAADPALWRTRPGVSSFA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCHHHHH
SDVEDITLGRLRLDLYARPGTPVREVIERELAAAAGNQLMRRALKLRILLAQACQRTGDG
HHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHALVVMGEALRFGAAEGFVRIFADEGDDVRRLVADACSRQSASLPAPYVERLLQACGQA
CEEEEEEHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
GSEQAAGTGRPAPAALVEPLTPKEQKVLQLLAEGYSNVAMAERLFVSETTVRTHLRNISA
CCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLHASNRTQAVAIARQLGLL
HHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]