BacMap

Definition	Ralstonia eutropha H16 chromosome 2, complete sequence.
Accession	NC_008314
Length	2,912,490

Click here to switch to the map view.

The map label for this gene is pldh-t [H]

Identifier: 116694682

GI number: 116694682

Start: 825060

End: 825833

Strand: Direct

Name: pldh-t [H]

Synonym: H16_B0731

Alternate gene names: 116694682

Gene position: 825060-825833 (Clockwise)

Preceding gene: 116694681

Following gene: 116694683

Centisome position: 28.33

GC content: 70.54

Gene sequence:

>774_bases
ATGCCTGAGGCAAACACCAACAACACGCTGCTGGCCGGGCGCAAGGTGCTGGTCACCGGCGCCGCGCGCGGACTGGGCCT
GGCCTTCGTCAAGGCGCTGGCCGAAGCCGGCGCCACCGTGGCCATGGCCGACATCCTGGCCGAGCGCCTGCAGCAGGAAG
CCGACGCCCTGCGCGCCCGCGGCCTGAAGGTGGTGCCGGTCACGCTGGACCTGTCCGATCCGGCCTCGGTGCAGGCTTGC
GCCGAGGCCGCGGTCAAGGCGCTGGGCGGGCTCGACGGCCTGGTCAACAACGCCGCCGTGACGGATTCCGGCGGCCGTGA
CGCCGCCGCCATCGACATCGCCACCTGGGACCGCGTGATGAACGTCAACGTGCGCGGCACCTGGCTGATGACCACCGCCT
GCCTGCCGGCGCTGCGCGCCAGCGGCCGCGGCGCCATCGTCAACCTGGCTTCGGACACGCCGCTGTGGGGCGCGCCCAAC
CTGCTTGCCTACGTGGCGAGCAAGAGCGCCATCATCGGCATGACCCGTTCGCTGGCGCGTGAACTGGGCAAGGACCAGAT
CACGGTGAACGCCGTGGCCCCGGGCCTGACGCTGGTGGAAGCCACCGAATACGTGCCGCAGCACCGGCACGACCTGTACC
GCGAGCAGCGCGCGATCACGCGCGAGCAACTGCCCGACGATGTTTGCGGCGCGGTGCTGTTTGCACTGTCCGACCTCGCC
CGTTTCGTGACCGGCCAGACGCTGGCGGTCAACGGCGGCTTTGTCATGCATTGA

Upstream 100 bases:

>100_bases
GCCGGCATTACCCGCGTGCGCCGCCTGCTCAAGCGCCGCGCCGAGCAGGAAGTGGCCGACGAGCCCGTCGCCATGCTGCA
ACCCGCCGGAGCCGCCAGCC

Downstream 100 bases:

>100_bases
TCCAACCGATCCACTGAAAACAGAAGGAATCCAAATGAGCGATCTTTCTCAACCGCAAAACATCAAGCGTTCCTGGGACC
AGCCGGAGAACGCTTCGTTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: tPLDH [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPEANTNNTLLAGRKVLVTGAARGLGLAFVKALAEAGATVAMADILAERLQQEADALRARGLKVVPVTLDLSDPASVQAC
AEAAVKALGGLDGLVNNAAVTDSGGRDAAAIDIATWDRVMNVNVRGTWLMTTACLPALRASGRGAIVNLASDTPLWGAPN
LLAYVASKSAIIGMTRSLARELGKDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAITREQLPDDVCGAVLFALSDLA
RFVTGQTLAVNGGFVMH

Sequences:

>Translated_257_residues
MPEANTNNTLLAGRKVLVTGAARGLGLAFVKALAEAGATVAMADILAERLQQEADALRARGLKVVPVTLDLSDPASVQAC
AEAAVKALGGLDGLVNNAAVTDSGGRDAAAIDIATWDRVMNVNVRGTWLMTTACLPALRASGRGAIVNLASDTPLWGAPN
LLAYVASKSAIIGMTRSLARELGKDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAITREQLPDDVCGAVLFALSDLA
RFVTGQTLAVNGGFVMH
>Mature_256_residues
PEANTNNTLLAGRKVLVTGAARGLGLAFVKALAEAGATVAMADILAERLQQEADALRARGLKVVPVTLDLSDPASVQACA
EAAVKALGGLDGLVNNAAVTDSGGRDAAAIDIATWDRVMNVNVRGTWLMTTACLPALRASGRGAIVNLASDTPLWGAPNL
LAYVASKSAIIGMTRSLARELGKDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAITREQLPDDVCGAVLFALSDLAR
FVTGQTLAVNGGFVMH

Specific function: Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6). Oxidizes pyridoxal to 4-pyridoxolactone, but does not have activity toward pyridoxal 5'-phosphate, pyridoxine, pyridoxamine, pyridoxamine 5'-phosphat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=31.9838056680162, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=31.640625, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.5490196078431, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=34.5381526104418, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.718875502008, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI40254986, Length=199, Percent_Identity=33.6683417085427, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=27.5303643724696, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=28.8702928870293, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=31, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=27.734375, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI142976729, Length=178, Percent_Identity=31.4606741573034, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=31.9587628865979, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.2, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=27.807486631016, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157739938, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI25282469, Length=214, Percent_Identity=28.5046728971963, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI302344755, Length=111, Percent_Identity=36.036036036036, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI59889578, Length=234, Percent_Identity=27.3504273504274, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI7706318, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=32.3699421965318, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI209862901, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=1e-10,
Organism=Homo sapiens, GI19923983, Length=204, Percent_Identity=27.4509803921569, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=33.9920948616601, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.8582677165354, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=32.9411764705882, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=30.8300395256917, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.843137254902, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=31.2, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=28.6852589641434, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=30.1587301587302, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787891, Length=246, Percent_Identity=28.0487804878049, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=26.0700389105058, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=199, Percent_Identity=28.643216080402, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=33.8645418326693, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=33.852140077821, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982365, Length=200, Percent_Identity=33, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.030303030303, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=29.9242424242424, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=29.0836653386454, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.9212598425197, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.3076923076923, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=28.4615384615385, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.5171102661597, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.7575757575758, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.9961977186312, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=28.4046692607004, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=27.2030651340996, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=177, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=32.0388349514563, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=186, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=207, Percent_Identity=30.9178743961353, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=28.3464566929134, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=27.4590163934426, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=28.6274509803922, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=196, Percent_Identity=34.1836734693878, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=27.5590551181102, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=27.2388059701493, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=170, Percent_Identity=27.6470588235294, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=256, Percent_Identity=27.34375, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=242, Percent_Identity=27.6859504132231, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=24.7148288973384, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=23.1939163498099, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=258, Percent_Identity=28.6821705426357, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=250, Percent_Identity=32, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=24.6031746031746, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=32.6612903225806, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=31.7460317460317, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357673, Length=199, Percent_Identity=32.6633165829146, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.2834645669291, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=33.4677419354839, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=30.8300395256917, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17737361, Length=190, Percent_Identity=35.7894736842105, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI161076933, Length=196, Percent_Identity=29.5918367346939, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24584748, Length=196, Percent_Identity=29.5918367346939, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=29.5336787564767, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364892, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=232, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=26.7676767676768, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221331218, Length=218, Percent_Identity=31.651376146789, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665243, Length=218, Percent_Identity=31.651376146789, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24647946, Length=210, Percent_Identity=29.5238095238095, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.107 [H]

Molecular weight: Translated: 26821; Mature: 26690

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEANTNNTLLAGRKVLVTGAARGLGLAFVKALAEAGATVAMADILAERLQQEADALRAR
CCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GLKVVPVTLDLSDPASVQACAEAAVKALGGLDGLVNNAAVTDSGGRDAAAIDIATWDRVM
CCEEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHCCCEEECCCCCCEEEEEEEEHHHEE
NVNVRGTWLMTTACLPALRASGRGAIVNLASDTPLWGAPNLLAYVASKSAIIGMTRSLAR
EECCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
ELGKDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAITREQLPDDVCGAVLFALSDLA
HCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RFVTGQTLAVNGGFVMH
HHHCCCEEEECCCEEEC
>Mature Secondary Structure 
PEANTNNTLLAGRKVLVTGAARGLGLAFVKALAEAGATVAMADILAERLQQEADALRAR
CCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GLKVVPVTLDLSDPASVQACAEAAVKALGGLDGLVNNAAVTDSGGRDAAAIDIATWDRVM
CCEEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHCCCEEECCCCCCEEEEEEEEHHHEE
NVNVRGTWLMTTACLPALRASGRGAIVNLASDTPLWGAPNLLAYVASKSAIIGMTRSLAR
EECCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
ELGKDQITVNAVAPGLTLVEATEYVPQHRHDLYREQRAITREQLPDDVCGAVLFALSDLA
HCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RFVTGQTLAVNGGFVMH
HHHCCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]