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The map label for this gene is crt [H]

Identifier: 116694649

GI number: 116694649

Start: 784604

End: 785383

Strand: Direct

Name: crt [H]

Synonym: H16_B0698

Alternate gene names: 116694649

Gene position: 784604-785383 (Clockwise)

Preceding gene: 116694648

Following gene: 116694650

Centisome position: 26.94

GC content: 68.85

Gene sequence:

>780_bases
ATGGAAACCATCCGCTTCGCCGTCGAGGACGGCATCGCCACGCTGACGCTGGACTCGCCGGCGCGCAAGAACGCGCTGTC
CTTGCCGATGCGCGACGAGATCGGCGAAGTGATTCGCCGGGTACGCGCCGACGACAGCGTGCGCGCGCTGATCCTGACCG
CCGCCGGCACCGATTTCTCGTCGGGCGGCGACATCAGCTCGATGCAGGTCGAGATCAATGCCGAGCAGGGCCGCAAGCGC
CTGCACAAGGTGCACGGCTGGCTGGAAGACCTGATCCAGCTCGACGTGCCGGTCATCGCCGCGGTGGACGGCGCGGCCTA
TGGCGCGGGCTTCAGCCTGGCGCTGACGGCCGACATCATCCTGGCCACGCCGCGCGCGCGCTTCGGGCTCCCGTTCCTGC
GCATGGGGCTGGTCCCCGACTGTGGCGTGTTCTACACGCTGCCGCGGATGATCGGCCTGCAGCGGGCCAAGGCGCTGATG
TTCTCGATGCGCGAGCTGAACGCCCAGGCCGCGCAAGACCTTGGCATCGTCATGGAAATCGTGCCGGCGGACAGCCTGCA
GGAACGTGCGCGGACGCTGGCGCAGGCCTTCACCGAGGCCTCGCCGGTGGCGGTGGGCCTGACCAAGCAGGCGCTGAACG
CCTCGCTGAACCAGGACCTGCACACCATGCTGGCGATGGAAGCGGACGGGCAGGGCATTGCCTTCTCCACTGCCTATCGC
CGCGAGGCTGCCGACCGCTTCATGGCCAAGCAGCCGCTGCGCTACCGCTGGCCGGACTGA

Upstream 100 bases:

>100_bases
AACTGGCGGCCGTGGTCGCCGGCGACACACCCAAGTGGGCCAGGATCGTGCGCGACGCCAATATCCAGCTCGACTGAAAC
CCGCCTCCCGGAGCCTACCG

Downstream 100 bases:

>100_bases
GCGGCGGCGCCGGTCATGCTGCTCCGCAGCATCCGGCTGCCTCGCCAGTCTGTCGTTTACGTATACAGGCGGGTGCTGGC
CGGACAGTACCGGTCGCCTG

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
METIRFAVEDGIATLTLDSPARKNALSLPMRDEIGEVIRRVRADDSVRALILTAAGTDFSSGGDISSMQVEINAEQGRKR
LHKVHGWLEDLIQLDVPVIAAVDGAAYGAGFSLALTADIILATPRARFGLPFLRMGLVPDCGVFYTLPRMIGLQRAKALM
FSMRELNAQAAQDLGIVMEIVPADSLQERARTLAQAFTEASPVAVGLTKQALNASLNQDLHTMLAMEADGQGIAFSTAYR
REAADRFMAKQPLRYRWPD

Sequences:

>Translated_259_residues
METIRFAVEDGIATLTLDSPARKNALSLPMRDEIGEVIRRVRADDSVRALILTAAGTDFSSGGDISSMQVEINAEQGRKR
LHKVHGWLEDLIQLDVPVIAAVDGAAYGAGFSLALTADIILATPRARFGLPFLRMGLVPDCGVFYTLPRMIGLQRAKALM
FSMRELNAQAAQDLGIVMEIVPADSLQERARTLAQAFTEASPVAVGLTKQALNASLNQDLHTMLAMEADGQGIAFSTAYR
REAADRFMAKQPLRYRWPD
>Mature_259_residues
METIRFAVEDGIATLTLDSPARKNALSLPMRDEIGEVIRRVRADDSVRALILTAAGTDFSSGGDISSMQVEINAEQGRKR
LHKVHGWLEDLIQLDVPVIAAVDGAAYGAGFSLALTADIILATPRARFGLPFLRMGLVPDCGVFYTLPRMIGLQRAKALM
FSMRELNAQAAQDLGIVMEIVPADSLQERARTLAQAFTEASPVAVGLTKQALNASLNQDLHTMLAMEADGQGIAFSTAYR
REAADRFMAKQPLRYRWPD

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=29.1497975708502, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI260274832, Length=235, Percent_Identity=28.936170212766, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI45643119, Length=235, Percent_Identity=28.936170212766, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI260275230, Length=235, Percent_Identity=28.936170212766, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=31.4741035856574, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI31542718, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=23.9043824701195, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=23.9043824701195, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI116235487, Length=176, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4757966, Length=225, Percent_Identity=24, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI51538581, Length=225, Percent_Identity=24, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI70995211, Length=225, Percent_Identity=28.4444444444444, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI68989263, Length=185, Percent_Identity=30.2702702702703, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20127408, Length=182, Percent_Identity=26.3736263736264, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=23.1075697211155, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=23.1075697211155, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4757968, Length=176, Percent_Identity=27.8409090909091, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI49355787, Length=176, Percent_Identity=27.8409090909091, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157694516, Length=239, Percent_Identity=25.9414225941423, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221307494, Length=225, Percent_Identity=23.5555555555556, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI213417737, Length=239, Percent_Identity=25.9414225941423, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=35.2713178294574, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI221142681, Length=209, Percent_Identity=34.4497607655502, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787659, Length=246, Percent_Identity=32.520325203252, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=32.9787234042553, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=31.9796954314721, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788597, Length=221, Percent_Identity=27.6018099547511, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082183, Length=212, Percent_Identity=24.0566037735849, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=220, Percent_Identity=31.3636363636364, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=31.0756972111554, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=29.4354838709677, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17535521, Length=248, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=215, Percent_Identity=26.9767441860465, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=244, Percent_Identity=24.5901639344262, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=217, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=189, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=25.1366120218579, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=213, Percent_Identity=23.4741784037559, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=30.8943089430894, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=30.8943089430894, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=30.6772908366534, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=33.0232558139535, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24654903, Length=172, Percent_Identity=26.1627906976744, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922422, Length=253, Percent_Identity=21.3438735177866, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357171, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28245; Mature: 28245

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIRFAVEDGIATLTLDSPARKNALSLPMRDEIGEVIRRVRADDSVRALILTAAGTDFS
CCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
SGGDISSMQVEINAEQGRKRLHKVHGWLEDLIQLDVPVIAAVDGAAYGAGFSLALTADII
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEEE
LATPRARFGLPFLRMGLVPDCGVFYTLPRMIGLQRAKALMFSMRELNAQAAQDLGIVMEI
EECCCHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VPADSLQERARTLAQAFTEASPVAVGLTKQALNASLNQDLHTMLAMEADGQGIAFSTAYR
CCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHH
REAADRFMAKQPLRYRWPD
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
METIRFAVEDGIATLTLDSPARKNALSLPMRDEIGEVIRRVRADDSVRALILTAAGTDFS
CCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCC
SGGDISSMQVEINAEQGRKRLHKVHGWLEDLIQLDVPVIAAVDGAAYGAGFSLALTADII
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEEE
LATPRARFGLPFLRMGLVPDCGVFYTLPRMIGLQRAKALMFSMRELNAQAAQDLGIVMEI
EECCCHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
VPADSLQERARTLAQAFTEASPVAVGLTKQALNASLNQDLHTMLAMEADGQGIAFSTAYR
CCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHH
REAADRFMAKQPLRYRWPD
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]