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The map label for this gene is rtxC2 [H]

Identifier: 116694644

GI number: 116694644

Start: 777887

End: 779239

Strand: Direct

Name: rtxC2 [H]

Synonym: H16_B0693

Alternate gene names: 116694644

Gene position: 777887-779239 (Clockwise)

Preceding gene: 116694643

Following gene: 116694646

Centisome position: 26.71

GC content: 67.85

Gene sequence:

>1353_bases
ATGACAACGACATGGTGCCGGCTGGCACATGTACTGCTATGGGCCGCCATGGTGGTGCCGCATCACGCGGCAGCCCAGGT
GCTGCGCCAGGCAGTCGAGCAAGCCGTGCATACCAATCCCGAAGTGCTGGCGGCGGGCAGCCGCCGGCTGGCCGCGGACG
AGGGGCTGACGCAGGCGCGCGCCGGTTACCTGCCGCGGGTCGATGTCAATGCCGCCACCGGTCGCGTACGCCTGGACAGC
CACAGCACCCGGCTGATGGGCCTGTCCGACTCTTCCTATGCCAGCCACGCCGCCGGCGTGACGATCTCGCAGATGCTGTT
CGACGGCTTTGCCACCAGCAGCGATGTGGAGCGCCAGGGCGCACGGATCGACGGCGCGGCCTATCGGGTCGGCGCGACTG
CCGAAGACATCGCGCTGCGCACGGTCGGCGTTTATGTGGAGGTCCTGCGGCGTCAGGAAACCGTGGCCATCGGCCTGGCC
AATCTGGAAGCGCACCAGCACATCTATGACCAGATCCGGCTTGGCGCCGACAACGGGGTGCTGCGCCGCGCCGATCTCTA
TCAGGTCGAAAGCCGCCTGGCGCTGGCCAAGGCCAGCCTGCGGGCGGAGCAGGGCAGCTTGCAGGACGCCATGACAGCCT
ATTTACGCGTGGTCGGCGCGCCGCCGGAGGTCTTGTCCAGGCCGGACTCGCTGTCGACGCTGCTGCCTGCCACCGAACGG
GAGGCGCAGCAGGTGGCAAACGCCAATCACCCCGCGCTGGGTGCCGGGCAGGCCGATATCGCCGAAGCCCAGGCCGGGCG
TTCGCTGGCCAAGGCCGCGTTGTGGCCAAGGCTGGATCTCGAGGTCGGCGTGGCGCGCGACCGCGACCGCGTGCTCGGCA
CCACCGACGAGCGCAGCGTGATGCTGCGCGTGCGCTACAACCTGTTTCGCGGCAACGCCGACAAGGCGCGCATCAACGAG
GCCGGCTACCAGGTCCAGGAAGCAGAGCAGAATCTGGACCGTCTGCGCAGACAGGTGCAGGAGGCCGTATCGCAGGCCTA
TAACGCCCACCTGACGGCGAAGGACCGTCTGGTGAGCCTCAAGCAATACGTGGAGGCCAGCGATGCCACGCGCGTCAGCT
ACGGCAAGCAATTCCGGATTGGGCAGCGCAGCCTGCTTGACCTGCTGAATGCCGAGAACGAGTACTTCAGCGCCAGCACG
GCCTACGTGACCGGCAAGTACAACGAACTGGCCAGCCAGTACCGCATCCTTGCCGGCATGGGCTTGCTATTGGCGACCCT
GCAGGTGCCGCCGCCCCAGACGGGGATGGTGCAGGTAGGGCAGCGGGCAGCGCCGCCGGTGGGACAGAGGTAG

Upstream 100 bases:

>100_bases
AGTTGAAAACCATAATAAACGGGTGGCGCACCGCTTCCCGTATCGCGCAGGCGCCGGCCAGCGCGATGCGCGGCAGCGGG
TGCGCCCGAGCGGGGGAAGC

Downstream 100 bases:

>100_bases
CGGGGGGACGGTGCCGGGCAAGCCGGCAGCCATGCTTCAGCCGCCGGCCACCGGAGATCCTGACCCGGCCCGCATCAGCG
CGGCAAAGCCTCTCCCCGCA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTTTWCRLAHVLLWAAMVVPHHAAAQVLRQAVEQAVHTNPEVLAAGSRRLAADEGLTQARAGYLPRVDVNAATGRVRLDS
HSTRLMGLSDSSYASHAAGVTISQMLFDGFATSSDVERQGARIDGAAYRVGATAEDIALRTVGVYVEVLRRQETVAIGLA
NLEAHQHIYDQIRLGADNGVLRRADLYQVESRLALAKASLRAEQGSLQDAMTAYLRVVGAPPEVLSRPDSLSTLLPATER
EAQQVANANHPALGAGQADIAEAQAGRSLAKAALWPRLDLEVGVARDRDRVLGTTDERSVMLRVRYNLFRGNADKARINE
AGYQVQEAEQNLDRLRRQVQEAVSQAYNAHLTAKDRLVSLKQYVEASDATRVSYGKQFRIGQRSLLDLLNAENEYFSAST
AYVTGKYNELASQYRILAGMGLLLATLQVPPPQTGMVQVGQRAAPPVGQR

Sequences:

>Translated_450_residues
MTTTWCRLAHVLLWAAMVVPHHAAAQVLRQAVEQAVHTNPEVLAAGSRRLAADEGLTQARAGYLPRVDVNAATGRVRLDS
HSTRLMGLSDSSYASHAAGVTISQMLFDGFATSSDVERQGARIDGAAYRVGATAEDIALRTVGVYVEVLRRQETVAIGLA
NLEAHQHIYDQIRLGADNGVLRRADLYQVESRLALAKASLRAEQGSLQDAMTAYLRVVGAPPEVLSRPDSLSTLLPATER
EAQQVANANHPALGAGQADIAEAQAGRSLAKAALWPRLDLEVGVARDRDRVLGTTDERSVMLRVRYNLFRGNADKARINE
AGYQVQEAEQNLDRLRRQVQEAVSQAYNAHLTAKDRLVSLKQYVEASDATRVSYGKQFRIGQRSLLDLLNAENEYFSAST
AYVTGKYNELASQYRILAGMGLLLATLQVPPPQTGMVQVGQRAAPPVGQR
>Mature_449_residues
TTTWCRLAHVLLWAAMVVPHHAAAQVLRQAVEQAVHTNPEVLAAGSRRLAADEGLTQARAGYLPRVDVNAATGRVRLDSH
STRLMGLSDSSYASHAAGVTISQMLFDGFATSSDVERQGARIDGAAYRVGATAEDIALRTVGVYVEVLRRQETVAIGLAN
LEAHQHIYDQIRLGADNGVLRRADLYQVESRLALAKASLRAEQGSLQDAMTAYLRVVGAPPEVLSRPDSLSTLLPATERE
AQQVANANHPALGAGQADIAEAQAGRSLAKAALWPRLDLEVGVARDRDRVLGTTDERSVMLRVRYNLFRGNADKARINEA
GYQVQEAEQNLDRLRRQVQEAVSQAYNAHLTAKDRLVSLKQYVEASDATRVSYGKQFRIGQRSLLDLLNAENEYFSASTA
YVTGKYNELASQYRILAGMGLLLATLQVPPPQTGMVQVGQRAAPPVGQR

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48938; Mature: 48807

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTWCRLAHVLLWAAMVVPHHAAAQVLRQAVEQAVHTNPEVLAAGSRRLAADEGLTQAR
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCHHHH
AGYLPRVDVNAATGRVRLDSHSTRLMGLSDSSYASHAAGVTISQMLFDGFATSSDVERQG
CCCCCCEECCCCCCEEEECCCCCEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHCC
ARIDGAAYRVGATAEDIALRTVGVYVEVLRRQETVAIGLANLEAHQHIYDQIRLGADNGV
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHCCCCCCC
LRRADLYQVESRLALAKASLRAEQGSLQDAMTAYLRVVGAPPEVLSRPDSLSTLLPATER
EEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCHHH
EAQQVANANHPALGAGQADIAEAQAGRSLAKAALWPRLDLEVGVARDRDRVLGTTDERSV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCE
MLRVRYNLFRGNADKARINEAGYQVQEAEQNLDRLRRQVQEAVSQAYNAHLTAKDRLVSL
EEEEEEHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KQYVEASDATRVSYGKQFRIGQRSLLDLLNAENEYFSASTAYVTGKYNELASQYRILAGM
HHHHHHCCCCCHHCCCHHCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
GLLLATLQVPPPQTGMVQVGQRAAPPVGQR
HHHHHHCCCCCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TTTWCRLAHVLLWAAMVVPHHAAAQVLRQAVEQAVHTNPEVLAAGSRRLAADEGLTQAR
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCHHHH
AGYLPRVDVNAATGRVRLDSHSTRLMGLSDSSYASHAAGVTISQMLFDGFATSSDVERQG
CCCCCCEECCCCCCEEEECCCCCEEEECCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHCC
ARIDGAAYRVGATAEDIALRTVGVYVEVLRRQETVAIGLANLEAHQHIYDQIRLGADNGV
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHHHHHHHCCCCCCC
LRRADLYQVESRLALAKASLRAEQGSLQDAMTAYLRVVGAPPEVLSRPDSLSTLLPATER
EEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCHHH
EAQQVANANHPALGAGQADIAEAQAGRSLAKAALWPRLDLEVGVARDRDRVLGTTDERSV
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCE
MLRVRYNLFRGNADKARINEAGYQVQEAEQNLDRLRRQVQEAVSQAYNAHLTAKDRLVSL
EEEEEEHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KQYVEASDATRVSYGKQFRIGQRSLLDLLNAENEYFSASTAYVTGKYNELASQYRILAGM
HHHHHHCCCCCHHCCCHHCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
GLLLATLQVPPPQTGMVQVGQRAAPPVGQR
HHHHHHCCCCCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]