Click here to switch to the map view.

The map label for this gene is rtxA2 [H]

Identifier: 116694643

GI number: 116694643

Start: 773062

End: 777720

Strand: Direct

Name: rtxA2 [H]

Synonym: H16_B0692

Alternate gene names: 116694643

Gene position: 773062-777720 (Clockwise)

Preceding gene: 116694642

Following gene: 116694644

Centisome position: 26.54

GC content: 64.76

Gene sequence:

>4659_bases
ATGGCAACCCTGACAGGTAGCAACGGCAGCGACAGCATCAGCGGCACCACGTCCGCCGACACCATCCTGAGCGGCAATGG
CAATGACTACGTCAGCGCCGGCGATGGCAACGACTATGTCGATGCCGGCAACGGCGACGATATCGTCGAAGGCGGCAGCG
GCGACGACACGCTGCTGGGCGCCAACGGCAAGGACCGGGTCTTCGGCGGGCTCGGCAATGACAACTTGTCGGGTGGCAAC
GGCACCGACGCGGTCTATGGCGGCGGCGGCGATGACGTGATCGGCAGCATCGACGGCTCGTCGGCGCTTTACACCGGCGA
CAATGGCGGCGATACGCTGTATGGCGACGGCTATGACAGCTACGCCGACTACCTGCTCGGTGCCGGCCATGAGTCAGCCC
GGCCGGGTAACGACCGCATCTATGGCGGCAACGGCGACGACCTGATCTACGGGGACAACGGCAACAATGCCGCCCTGGGC
GGCGACGACATCATTGCCGGTGGCAACGGCAAGGACACCATCTACGGTGAAGGCGGCAACGACAAGATCGCCGGCGGGGC
AGGCGGCGACACCCTGAGCGGCGGCAGCGGCGCCGACGTCTTTGTCTATAACGCCGTCTCCGACTCCACCGCGGCCGGCA
TGGATGTGATCACCGACTTCCAGCGCGGCGTGGACCACCTCGACTTGCGGCCCGTGCTGGGCGACACTGGCTTTGAATGG
GGTGGCCGCCAGCCCACGGCCCACGGAGCCTGGTTCCAGCAATCGGGGGGCAATACCTATGTCTACGTGGATGTCGACGG
CAATCCCGCCACGGCGGAAATGGTCATCAAGCTCAACGGCCTGCACGAACTGACCAAGTCGGACTTCGCTGGCTACGACA
ACCATGCGCCAACGGCAGTGGCCGATACCCACGCGATCGGCGAGAACAACTCTCCGAACCCGATCACCGGCAATGTGCTG
TCGAACGACAGCGACGTCGATGCGGGGAACGTGCTGGCCGTGGCCAATCCCGGCACTTATGCCGGCCAGTACGGCACGCT
GACGCTCCACGCCGACGGCAGCTACAGCTATGAGCTGGACAACGGCAATGGCCAGGTGCAGGCATTGCGGCAGGGCCAGC
AAGTCCAGGACACGTTCAACTATGAGGTGTCCGACGGGCAGGCCAGCGCGGCTTCATCGCTGAGCATCCGGATTACTGGT
GCCAACGATGGAGCCACGATCACGGCCTCGGACAGCGAAGACAAGGCGGTAACCGAGGCTGGCGGCGCAGGCAACACCGA
CCTCGGCGACGCCTCCGCCAGCGGCAAGCTGACGGTCACTGACGTCGATACCGGTGAAGCGCACTTTGCCGCAGTGCCGC
CGGAGAGTCTGGCAGGACAGTACGGCACCTTCAGCTTCGACAGCAACACCGGCGCCTGGAGCTACACGCTCGACAACACC
AAGGCCGATGTGCTGATCGCGGGGCAGCAGGTCAGCGATTCGCTGACGGTGTCCTCCGCCGACCAGAGCGCGCAGCAGAC
CATCAAGGTCGACATCACCGGTGCCAACGACCACGCCACCATCTCGGCCTCGGCCAGTGAGGACAAGGCGGTCACCGAAG
CCGGCGGCGCAGGCAACACCGACCTCGGCGACGGCTCCGCCAGCGGCAAGCTGACGGTTACTGACGTCGATGCCGGTGAA
GCGCACTTCGCCGCGGTGGCGCCGGACAGCCTGGTCGGGCAGTACGGCACCTTCGCCTTCGACAGCAACACCGGCGCCTG
GACCTATACGCTGGACAACACCAAGGCCGATGCGCTGATCGCGGGCCAGCAGGTCAGTGATTCGCTGACGGTGTCCTCCG
CCGACCAGACGGCGCAGCAGACCATCAAGGTCGACATCACCGGTGCCAACGACCATGCCACCATCACGTCCTCGGCCAGC
GAGGACAAGGTGGTGACCGAGGCTGGCGGCGCAGGCAATGCTGAAACGGGTGACGCCTCCGCCAGCGGCAAGCTGACGGT
CACTGACGTCGATACCGGTGAAGCGCACTTTGCCGCAGTGCCGCCGGAGAGTCTGGCAGGACAGTACGGCACCTTCAGCT
TCGACAGCAACACCGGCGCCTGGAGCTATACGCTCGACAACACCAAGGCCGATGTGCTGATCGCGGGCCAGCAGGTCAGC
GATTCGCTGACGGTGTCCTCCGCCGACCAGAGCGCGCAGCAGACCATCAAGGTCGACATCACCGGTGCCAACGACCACGC
CACCATCTCGGCCTCGGCCAGTGAGGACAAGGCGGTCACCGAAGCCGGCGGCGCAGGCAACACCGACCTCGGCGACGCCT
CCGCCAGCGGCAAGCTGACGGTTACTGACGTCGATGCCGGTGAAGCGCACTTCGCCGCGGTGGCGCCGGACAGCCTGGTC
GGGCAGTACGGCACCTTCACCTTCGACAGCAACACCGGCGCCTGGACCTATACGCTGGACAACACCAAGGCCGATGCGCT
GATCGCGGGCCAGCAGGTCAGTGATTCGCTGACGGTGGCTTCGGCCGACCACACGGCGCAGCAGACCATCACCGTCAACA
TCACCGGCGCAAACGACTACGCTACGATCACGGCTTCAGCCAGCGAGGACACCTCGGTGACCGAAGCCGGCGGGGCAGGA
AATGCCATTCCCGGCGACCCCTCCGCCCGCGGCACGTTGACAGTCAACGATGTCGATACCGGCGATGCGCACTTTGCCGC
CGTGCCGCCAGCGAGCCTGGTCGGCCAATACGGCGCCTTCACCTTCGATAGCGGCACCGGCGCCTGGACCTACACGCTGG
ACAACAGCAAGGCGCAGTCCCTCGCCGCGGGCCAGCATGTGACCGACTCGCTGTCCGTACAGTCGGCCGATCTCAGTGCC
ACCCAGGCGATCACCGTCAACATCACAGGTGCCAACGATGCTGCGGTGAATGCCGTTCCCCTTGCGCAGGTGGTCAACGA
AGATACGCCATTGGTGTTCCGTACGGCCAACGGCAATGCACTCAGCATCTCTGACGTGGACAACGCGAGCCACACCGTGA
CGCTGAGCGCAAGCCACGGCGCGATCACGCTGAATGGCGTTGCCGGGCTGCAGTTCCTGTCGGGCGACGGCACCGCGGAC
AGCACCATGACATTCACGGGCAGCGATGCGGCAATCAATGCTGCGCTGAATGGAATGAGCTTCCTTGGCGAGAAGGATTA
TGCGGGCGCCGCGTCGGTGCAGATCCAGACCAGCGATGGCGCTTTGGTCGATACCGATACGGTGGCGATTACGGTCAATC
CCGTCAATGACGCGCCGGTGGCAGCCGAGGACGTTGTCTATGTTTCGACTAACACCGACAACATCCTGATTCCGGTGAGC
GCGCTGCTCGGCAACGACGTCGATATCGACGGGCGGGCCTTGTCCATAAACCCGCTCAGTCTGACCTCAAGCACGCTTTC
CGGCCTGAGGCTTGTCACCGAAAGCAATTACAGCTTCGTCGCGTTCGACAGTCCCAACAGCAAGGGGGTGGCAACCTTCA
GCTATACCGTCGAAGACGGGGCAGGTGGCAGCAGCACGGCGACGGTGACCGTCAATGTCGTGGACAAAAACGGCTTTTCG
CTTGATCAGGCCAGCTACCAGGCTTCCTATCTGGAGGGTGGCAGCAATCCCGACAGCATGACTGGTGCCGTTGCGGGTGA
CATCTTCATTGGCGGACGTGGTACCGACATCCTCAACGGCGGGAACGGCGACGACGTCTTGAGAGGGGGCGCCGACAACG
ACACCCTCAACGGCGGGATCGGCGACGACGTCTTGAGAGGTGGCGCCGACAACGACACCATCGACGGGGGGGTGGGCATA
GATATGCTGGATTTCTCCGATGCCACCGGCGCGGTCTCCTTCACGTTGATCCAAAGTAGCACCCTCGTCAAGGTGCTTGT
GGGCGCGACGCCCGGACTAGGTACCGACAGCTACGCGAACATGGAGGGCGTGATCGGCTCGGCGTTTGTCGACACGCTGA
CCGGCAGCTCCGCCAACGACGTCATTCGCGGTGGCGCGGGCGATGACACCATCAACGGCGGCGACGGCATCGACCTGCTT
GATTTCTCCGATGCCACCGGCGGGGTTGTGTTCACGCTGACGCAGAGCGGCAGCCCCACCACGGCAGGCCCGGGCGTGAC
TGGCCTCGGTGCCGACAGCTACAGCAACATGGAAGGCGTCATCGGCTCCGCCTTCAACGACAACCTCACCGGCTCTGCCG
GCAACGACGTGCTGCGTGGCGGCGCGGGCAACGACGTGTTGGTCGGAGGCGCCGGCAACGACGTGTTGACCGGCGGCGCC
GGCGCCGACACACTGACCGGCGGCAATGGCAGCGACACCTTTCGCTTTCTGCGCGCGGACCCCGCTTCGGTCGACACCAT
CACCGACTTCGGTGCGGCTCCCGTGGCTTCCGGTGGCGATGTGCTGGATCTTTCCGATCTGCTTTCCGGTGTTGGCGTGA
ACCCTGCCAACGCGGCGCAGTTCGTCCGCCTTTCGGAGGTGGGTGGCAACACCGTGGTCAGCCTGGATCGTGACGGCAGT
GGCACGGCGGCTGCATTCCAGGACGTGGCGGTGCTGCAGGGCGTGGTCGGGCTCGATCTCAACACGCTGTTGAGCAACGG
CAATCTCCACACCGCCTGA

Upstream 100 bases:

>100_bases
GGGAACTGGCGTTCCGGGAACGATAAGAGCGGGCGGTTTGCCCACGACGACAACAAGCAAGGCATGGCCAGCAGGCTGGC
ATTCAGGACGGAGAGTGATC

Downstream 100 bases:

>100_bases
GGCGGGCGATCGGTGGCGGATTCAGAGAGGGAAATGCAGGGCGGCAGTAAAGCCGGAATCCGGCGCAGTTGAAAACCATA
ATAAACGGGTGGCGCACCGC

Product: RTX toxin exported protein

Products: NA

Alternate protein names: AC-HLY; ACT; Cyclolysin; ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 1552; Mature: 1551

Protein sequence:

>1552_residues
MATLTGSNGSDSISGTTSADTILSGNGNDYVSAGDGNDYVDAGNGDDIVEGGSGDDTLLGANGKDRVFGGLGNDNLSGGN
GTDAVYGGGGDDVIGSIDGSSALYTGDNGGDTLYGDGYDSYADYLLGAGHESARPGNDRIYGGNGDDLIYGDNGNNAALG
GDDIIAGGNGKDTIYGEGGNDKIAGGAGGDTLSGGSGADVFVYNAVSDSTAAGMDVITDFQRGVDHLDLRPVLGDTGFEW
GGRQPTAHGAWFQQSGGNTYVYVDVDGNPATAEMVIKLNGLHELTKSDFAGYDNHAPTAVADTHAIGENNSPNPITGNVL
SNDSDVDAGNVLAVANPGTYAGQYGTLTLHADGSYSYELDNGNGQVQALRQGQQVQDTFNYEVSDGQASAASSLSIRITG
ANDGATITASDSEDKAVTEAGGAGNTDLGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNT
KADVLIAGQQVSDSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDGSASGKLTVTDVDAGE
AHFAAVAPDSLVGQYGTFAFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVSSADQTAQQTIKVDITGANDHATITSSAS
EDKVVTEAGGAGNAETGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTKADVLIAGQQVS
DSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDASASGKLTVTDVDAGEAHFAAVAPDSLV
GQYGTFTFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVASADHTAQQTITVNITGANDYATITASASEDTSVTEAGGAG
NAIPGDPSARGTLTVNDVDTGDAHFAAVPPASLVGQYGAFTFDSGTGAWTYTLDNSKAQSLAAGQHVTDSLSVQSADLSA
TQAITVNITGANDAAVNAVPLAQVVNEDTPLVFRTANGNALSISDVDNASHTVTLSASHGAITLNGVAGLQFLSGDGTAD
STMTFTGSDAAINAALNGMSFLGEKDYAGAASVQIQTSDGALVDTDTVAITVNPVNDAPVAAEDVVYVSTNTDNILIPVS
ALLGNDVDIDGRALSINPLSLTSSTLSGLRLVTESNYSFVAFDSPNSKGVATFSYTVEDGAGGSSTATVTVNVVDKNGFS
LDQASYQASYLEGGSNPDSMTGAVAGDIFIGGRGTDILNGGNGDDVLRGGADNDTLNGGIGDDVLRGGADNDTIDGGVGI
DMLDFSDATGAVSFTLIQSSTLVKVLVGATPGLGTDSYANMEGVIGSAFVDTLTGSSANDVIRGGAGDDTINGGDGIDLL
DFSDATGGVVFTLTQSGSPTTAGPGVTGLGADSYSNMEGVIGSAFNDNLTGSAGNDVLRGGAGNDVLVGGAGNDVLTGGA
GADTLTGGNGSDTFRFLRADPASVDTITDFGAAPVASGGDVLDLSDLLSGVGVNPANAAQFVRLSEVGGNTVVSLDRDGS
GTAAAFQDVAVLQGVVGLDLNTLLSNGNLHTA

Sequences:

>Translated_1552_residues
MATLTGSNGSDSISGTTSADTILSGNGNDYVSAGDGNDYVDAGNGDDIVEGGSGDDTLLGANGKDRVFGGLGNDNLSGGN
GTDAVYGGGGDDVIGSIDGSSALYTGDNGGDTLYGDGYDSYADYLLGAGHESARPGNDRIYGGNGDDLIYGDNGNNAALG
GDDIIAGGNGKDTIYGEGGNDKIAGGAGGDTLSGGSGADVFVYNAVSDSTAAGMDVITDFQRGVDHLDLRPVLGDTGFEW
GGRQPTAHGAWFQQSGGNTYVYVDVDGNPATAEMVIKLNGLHELTKSDFAGYDNHAPTAVADTHAIGENNSPNPITGNVL
SNDSDVDAGNVLAVANPGTYAGQYGTLTLHADGSYSYELDNGNGQVQALRQGQQVQDTFNYEVSDGQASAASSLSIRITG
ANDGATITASDSEDKAVTEAGGAGNTDLGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNT
KADVLIAGQQVSDSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDGSASGKLTVTDVDAGE
AHFAAVAPDSLVGQYGTFAFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVSSADQTAQQTIKVDITGANDHATITSSAS
EDKVVTEAGGAGNAETGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTKADVLIAGQQVS
DSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDASASGKLTVTDVDAGEAHFAAVAPDSLV
GQYGTFTFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVASADHTAQQTITVNITGANDYATITASASEDTSVTEAGGAG
NAIPGDPSARGTLTVNDVDTGDAHFAAVPPASLVGQYGAFTFDSGTGAWTYTLDNSKAQSLAAGQHVTDSLSVQSADLSA
TQAITVNITGANDAAVNAVPLAQVVNEDTPLVFRTANGNALSISDVDNASHTVTLSASHGAITLNGVAGLQFLSGDGTAD
STMTFTGSDAAINAALNGMSFLGEKDYAGAASVQIQTSDGALVDTDTVAITVNPVNDAPVAAEDVVYVSTNTDNILIPVS
ALLGNDVDIDGRALSINPLSLTSSTLSGLRLVTESNYSFVAFDSPNSKGVATFSYTVEDGAGGSSTATVTVNVVDKNGFS
LDQASYQASYLEGGSNPDSMTGAVAGDIFIGGRGTDILNGGNGDDVLRGGADNDTLNGGIGDDVLRGGADNDTIDGGVGI
DMLDFSDATGAVSFTLIQSSTLVKVLVGATPGLGTDSYANMEGVIGSAFVDTLTGSSANDVIRGGAGDDTINGGDGIDLL
DFSDATGGVVFTLTQSGSPTTAGPGVTGLGADSYSNMEGVIGSAFNDNLTGSAGNDVLRGGAGNDVLVGGAGNDVLTGGA
GADTLTGGNGSDTFRFLRADPASVDTITDFGAAPVASGGDVLDLSDLLSGVGVNPANAAQFVRLSEVGGNTVVSLDRDGS
GTAAAFQDVAVLQGVVGLDLNTLLSNGNLHTA
>Mature_1551_residues
ATLTGSNGSDSISGTTSADTILSGNGNDYVSAGDGNDYVDAGNGDDIVEGGSGDDTLLGANGKDRVFGGLGNDNLSGGNG
TDAVYGGGGDDVIGSIDGSSALYTGDNGGDTLYGDGYDSYADYLLGAGHESARPGNDRIYGGNGDDLIYGDNGNNAALGG
DDIIAGGNGKDTIYGEGGNDKIAGGAGGDTLSGGSGADVFVYNAVSDSTAAGMDVITDFQRGVDHLDLRPVLGDTGFEWG
GRQPTAHGAWFQQSGGNTYVYVDVDGNPATAEMVIKLNGLHELTKSDFAGYDNHAPTAVADTHAIGENNSPNPITGNVLS
NDSDVDAGNVLAVANPGTYAGQYGTLTLHADGSYSYELDNGNGQVQALRQGQQVQDTFNYEVSDGQASAASSLSIRITGA
NDGATITASDSEDKAVTEAGGAGNTDLGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTK
ADVLIAGQQVSDSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDGSASGKLTVTDVDAGEA
HFAAVAPDSLVGQYGTFAFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVSSADQTAQQTIKVDITGANDHATITSSASE
DKVVTEAGGAGNAETGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTKADVLIAGQQVSD
SLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDASASGKLTVTDVDAGEAHFAAVAPDSLVG
QYGTFTFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVASADHTAQQTITVNITGANDYATITASASEDTSVTEAGGAGN
AIPGDPSARGTLTVNDVDTGDAHFAAVPPASLVGQYGAFTFDSGTGAWTYTLDNSKAQSLAAGQHVTDSLSVQSADLSAT
QAITVNITGANDAAVNAVPLAQVVNEDTPLVFRTANGNALSISDVDNASHTVTLSASHGAITLNGVAGLQFLSGDGTADS
TMTFTGSDAAINAALNGMSFLGEKDYAGAASVQIQTSDGALVDTDTVAITVNPVNDAPVAAEDVVYVSTNTDNILIPVSA
LLGNDVDIDGRALSINPLSLTSSTLSGLRLVTESNYSFVAFDSPNSKGVATFSYTVEDGAGGSSTATVTVNVVDKNGFSL
DQASYQASYLEGGSNPDSMTGAVAGDIFIGGRGTDILNGGNGDDVLRGGADNDTLNGGIGDDVLRGGADNDTIDGGVGID
MLDFSDATGAVSFTLIQSSTLVKVLVGATPGLGTDSYANMEGVIGSAFVDTLTGSSANDVIRGGAGDDTINGGDGIDLLD
FSDATGGVVFTLTQSGSPTTAGPGVTGLGADSYSNMEGVIGSAFNDNLTGSAGNDVLRGGAGNDVLVGGAGNDVLTGGAG
ADTLTGGNGSDTFRFLRADPASVDTITDFGAAPVASGGDVLDLSDLLSGVGVNPANAAQFVRLSEVGGNTVVSLDRDGSG
TAAAFQDVAVLQGVVGLDLNTLLSNGNLHTA

Specific function: This adenylate cyclase belongs to a special class of bacterial toxin. It causes whooping cough by acting on mammalian cells by elevating cAMP-concentration and thus disrupts normal cell function [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 17 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005165
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR018504
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF03497 Anthrax_toxA; PF00353 HemolysinCabind; PF02382 RTX [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 154563; Mature: 154432

Theoretical pI: Translated: 3.61; Mature: 3.61

Prosite motif: PS00018 EF_HAND_1 ; PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLTGSNGSDSISGTTSADTILSGNGNDYVSAGDGNDYVDAGNGDDIVEGGSGDDTLLG
CEEEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEECCCCCCEEECCCCCCEEEC
ANGKDRVFGGLGNDNLSGGNGTDAVYGGGGDDVIGSIDGSSALYTGDNGGDTLYGDGYDS
CCCCCCEEECCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEEEECCCCCCCEECCCCHH
YADYLLGAGHESARPGNDRIYGGNGDDLIYGDNGNNAALGGDDIIAGGNGKDTIYGEGGN
HHHHHHCCCCCCCCCCCCEEECCCCCEEEECCCCCCCEECCCCEEECCCCCCEEEECCCC
DKIAGGAGGDTLSGGSGADVFVYNAVSDSTAAGMDVITDFQRGVDHLDLRPVLGDTGFEW
CEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEECEEEECCCCCCC
GGRQPTAHGAWFQQSGGNTYVYVDVDGNPATAEMVIKLNGLHELTKSDFAGYDNHAPTAV
CCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCEE
ADTHAIGENNSPNPITGNVLSNDSDVDAGNVLAVANPGTYAGQYGTLTLHADGSYSYELD
ECCEECCCCCCCCCEECCEECCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCEEEEEE
NGNGQVQALRQGQQVQDTFNYEVSDGQASAASSLSIRITGANDGATITASDSEDKAVTEA
CCCCEEEEECCCCHHHHHCCEEECCCCCCCCCEEEEEEEECCCCCEEEECCCCCCEEEEC
GGAGNTDLGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNT
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHCCCCCEEEECCCCCEEEEEECCC
KADVLIAGQQVSDSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNT
CEEEEEECCCCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCHHCCCCCCC
DLGDGSASGKLTVTDVDAGEAHFAAVAPDSLVGQYGTFAFDSNTGAWTYTLDNTKADALI
CCCCCCCCCEEEEEECCCCCCEEEEECCHHHHCCCCEEEEECCCCEEEEEECCCCCCEEE
AGQQVSDSLTVSSADQTAQQTIKVDITGANDHATITSSASEDKVVTEAGGAGNAETGDAS
ECCCCCCCEEEECCCCCCEEEEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCC
ASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTKADVLIAGQQVS
CCCCEEEEECCCCCEEEEECCCHHHCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCC
DSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDASASGKLT
CCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTDVDAGEAHFAAVAPDSLVGQYGTFTFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVA
EEECCCCCCEEEEECCHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCEEEE
SADHTAQQTITVNITGANDYATITASASEDTSVTEAGGAGNAIPGDPSARGTLTVNDVDT
ECCCCCEEEEEEEEECCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCC
GDAHFAAVPPASLVGQYGAFTFDSGTGAWTYTLDNSKAQSLAAGQHVTDSLSVQSADLSA
CCCEEEECCCHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHCCCCCCCCCEEEECCCCE
TQAITVNITGANDAAVNAVPLAQVVNEDTPLVFRTANGNALSISDVDNASHTVTLSASHG
EEEEEEEEECCCCCCCCEEEHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCC
AITLNGVAGLQFLSGDGTADSTMTFTGSDAAINAALNGMSFLGEKDYAGAASVQIQTSDG
EEEEECCCEEEEEECCCCCCCEEEEECCCCEEEEHHCCHHHCCCCCCCCEEEEEEECCCC
ALVDTDTVAITVNPVNDAPVAAEDVVYVSTNTDNILIPVSALLGNDVDIDGRALSINPLS
CEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCCCEEEEECCCC
LTSSTLSGLRLVTESNYSFVAFDSPNSKGVATFSYTVEDGAGGSSTATVTVNVVDKNGFS
CCCHHHCCEEEEEECCEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEEEEEEEECCCCC
LDQASYQASYLEGGSNPDSMTGAVAGDIFIGGRGTDILNGGNGDDVLRGGADNDTLNGGI
CCHHHHEHHHHCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCHHEECCCCCCCCCCCC
GDDVLRGGADNDTIDGGVGIDMLDFSDATGAVSFTLIQSSTLVKVLVGATPGLGTDSYAN
CHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCC
MEGVIGSAFVDTLTGSSANDVIRGGAGDDTINGGDGIDLLDFSDATGGVVFTLTQSGSPT
CCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCC
TAGPGVTGLGADSYSNMEGVIGSAFNDNLTGSAGNDVLRGGAGNDVLVGGAGNDVLTGGA
CCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEECCC
GADTLTGGNGSDTFRFLRADPASVDTITDFGAAPVASGGDVLDLSDLLSGVGVNPANAAQ
CCCCCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEHHHHHHCCCCCCCCHHE
FVRLSEVGGNTVVSLDRDGSGTAAAFQDVAVLQGVVGLDLNTLLSNGNLHTA
EEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
ATLTGSNGSDSISGTTSADTILSGNGNDYVSAGDGNDYVDAGNGDDIVEGGSGDDTLLG
EEEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEECCCCCCEEECCCCCCEEEC
ANGKDRVFGGLGNDNLSGGNGTDAVYGGGGDDVIGSIDGSSALYTGDNGGDTLYGDGYDS
CCCCCCEEECCCCCCCCCCCCCCEEECCCCCCEEEECCCCCEEEECCCCCCCEECCCCHH
YADYLLGAGHESARPGNDRIYGGNGDDLIYGDNGNNAALGGDDIIAGGNGKDTIYGEGGN
HHHHHHCCCCCCCCCCCCEEECCCCCEEEECCCCCCCEECCCCEEECCCCCCEEEECCCC
DKIAGGAGGDTLSGGSGADVFVYNAVSDSTAAGMDVITDFQRGVDHLDLRPVLGDTGFEW
CEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCEECEEEECCCCCCC
GGRQPTAHGAWFQQSGGNTYVYVDVDGNPATAEMVIKLNGLHELTKSDFAGYDNHAPTAV
CCCCCCCCCCEEEECCCCEEEEEEECCCCCCEEEEEEECCHHHHHHHHCCCCCCCCCCEE
ADTHAIGENNSPNPITGNVLSNDSDVDAGNVLAVANPGTYAGQYGTLTLHADGSYSYELD
ECCEECCCCCCCCCEECCEECCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCEEEEEE
NGNGQVQALRQGQQVQDTFNYEVSDGQASAASSLSIRITGANDGATITASDSEDKAVTEA
CCCCEEEEECCCCHHHHHCCEEECCCCCCCCCEEEEEEEECCCCCEEEECCCCCCEEEEC
GGAGNTDLGDASASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNT
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHCCCCCEEEECCCCCEEEEEECCC
KADVLIAGQQVSDSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNT
CEEEEEECCCCCCCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCHHCCCCCCC
DLGDGSASGKLTVTDVDAGEAHFAAVAPDSLVGQYGTFAFDSNTGAWTYTLDNTKADALI
CCCCCCCCCEEEEEECCCCCCEEEEECCHHHHCCCCEEEEECCCCEEEEEECCCCCCEEE
AGQQVSDSLTVSSADQTAQQTIKVDITGANDHATITSSASEDKVVTEAGGAGNAETGDAS
ECCCCCCCEEEECCCCCCEEEEEEEEECCCCCEEEECCCCCCEEEEECCCCCCCCCCCCC
ASGKLTVTDVDTGEAHFAAVPPESLAGQYGTFSFDSNTGAWSYTLDNTKADVLIAGQQVS
CCCCEEEEECCCCCEEEEECCCHHHCCCCCEEEECCCCCEEEEEECCCCEEEEEECCCCC
DSLTVSSADQSAQQTIKVDITGANDHATISASASEDKAVTEAGGAGNTDLGDASASGKLT
CCEEEECCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTDVDAGEAHFAAVAPDSLVGQYGTFTFDSNTGAWTYTLDNTKADALIAGQQVSDSLTVA
EEECCCCCCEEEEECCHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEECCCCCCCEEEE
SADHTAQQTITVNITGANDYATITASASEDTSVTEAGGAGNAIPGDPSARGTLTVNDVDT
ECCCCCEEEEEEEEECCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCC
GDAHFAAVPPASLVGQYGAFTFDSGTGAWTYTLDNSKAQSLAAGQHVTDSLSVQSADLSA
CCCEEEECCCHHHHHCCCCEEEECCCCEEEEEECCCCHHHHHCCCCCCCCCEEEECCCCE
TQAITVNITGANDAAVNAVPLAQVVNEDTPLVFRTANGNALSISDVDNASHTVTLSASHG
EEEEEEEEECCCCCCCCEEEHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCC
AITLNGVAGLQFLSGDGTADSTMTFTGSDAAINAALNGMSFLGEKDYAGAASVQIQTSDG
EEEEECCCEEEEEECCCCCCCEEEEECCCCEEEEHHCCHHHCCCCCCCCEEEEEEECCCC
ALVDTDTVAITVNPVNDAPVAAEDVVYVSTNTDNILIPVSALLGNDVDIDGRALSINPLS
CEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEEHHHHCCCCCCCCEEEEECCCC
LTSSTLSGLRLVTESNYSFVAFDSPNSKGVATFSYTVEDGAGGSSTATVTVNVVDKNGFS
CCCHHHCCEEEEEECCEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEEEEEEEECCCCC
LDQASYQASYLEGGSNPDSMTGAVAGDIFIGGRGTDILNGGNGDDVLRGGADNDTLNGGI
CCHHHHEHHHHCCCCCCCCCCEEEEEEEEECCCCCEEECCCCCCHHEECCCCCCCCCCCC
GDDVLRGGADNDTIDGGVGIDMLDFSDATGAVSFTLIQSSTLVKVLVGATPGLGTDSYAN
CHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCC
MEGVIGSAFVDTLTGSSANDVIRGGAGDDTINGGDGIDLLDFSDATGGVVFTLTQSGSPT
CCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCC
TAGPGVTGLGADSYSNMEGVIGSAFNDNLTGSAGNDVLRGGAGNDVLVGGAGNDVLTGGA
CCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEEECCC
GADTLTGGNGSDTFRFLRADPASVDTITDFGAAPVASGGDVLDLSDLLSGVGVNPANAAQ
CCCCCCCCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEHHHHHHCCCCCCCCHHE
FVRLSEVGGNTVVSLDRDGSGTAAAFQDVAVLQGVVGLDLNTLLSNGNLHTA
EEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7557410; 12910271 [H]