BacMap

Definition	Ralstonia eutropha H16 chromosome 2, complete sequence.
Accession	NC_008314
Length	2,912,490

Click here to switch to the map view.

The map label for this gene is fabG2 [H]

Identifier: 116694617

GI number: 116694617

Start: 740852

End: 741655

Strand: Direct

Name: fabG2 [H]

Synonym: H16_B0666

Alternate gene names: 116694617

Gene position: 740852-741655 (Clockwise)

Preceding gene: 116694616

Following gene: 116694618

Centisome position: 25.44

GC content: 68.28

Gene sequence:

>804_bases
ATGACCCTGAACACCGAAATCCCCAGCGGCCCGGCCTATGTGCCTGGCCATCAGTTGCTCGCCGGCAAGAGTGTGCTCAT
CACCGCCGCGGCGGGCGCCGGCATCGGCTTTGCCGCCGCGCGCCGCTGCGCCGAGGAGGGCTGCCGCGCGCTGATGATCT
CCGACGTCCATGAGAAGCGCCTGGCCGAAGCGGTCGGGCGCCTGCGCGCGGAAACCGGCCTGCAGGCGATCCATGGCCAG
CTTTGCGATGTATCGGATGAAGCGCAGGTGCGCGCACTTGTGGCCGCCGCCGAAGAAGCCTTGGGCGGAACCGACGTGCT
GATCAACAACGCCGGCCTGGGCGGCTCGCGCCGCCTAGTTGATATGGACGATGCCGAGTGGTCGCGCGTGATCGATATTT
CCCTCACGGGCACCTTCCGCATGACGCGAGCGATGTTGCCGCACATGCAGGCGCGCCGGCGCGGCGCCATCGTCAACAAC
GCCTCGGTGCTGGGCTGGCGTGCGCAGAAGGAGCAGTCGCACTACGCCGCGGCCAAGGCCGGGGTGATGGCGCTGACGCG
CTGCAGCGCGATGGAAGCCGCCGAATTTGGCGTGCGCATCAATGCGGTGGCGCCCAGCATCGCGCTGCATGACTTCCTGA
AGAAGTCGGCGCCGGCCGACCTGCTGCGCCAGCTCAGCGAGCGCGAAGCGTTCGGGCGCGCGGCCGAGGTGTGGGAGGTG
GCCAATGTGATGGTATTCCTGGCCAGCGACTATGCCTCGTACATGACGGGCGAGGTGCTGCCGGTGAGCAGCCAGCGGGC
TTGA

Upstream 100 bases:

>100_bases
TCTCGCGCGCCGACACCATCTACGCCGGCACCAACGAAATCCAGCTCAACATCATCGCCGAACGCGGCCTCGGCATGCCG
CGCGAAGCACGAGGACAGTC

Downstream 100 bases:

>100_bases
AGGGAAACAGTTGGGACCGGGAACAACGCAGGAACCAGACATGCCAAGAATCTTCCGTTCTGCCGAAGACATCCACGCCG
CCGTCGGCCAGCGCCTCGGC

Product: short chain dehydrogenase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTLNTEIPSGPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDVHEKRLAEAVGRLRAETGLQAIHGQ
LCDVSDEAQVRALVAAAEEALGGTDVLINNAGLGGSRRLVDMDDAEWSRVIDISLTGTFRMTRAMLPHMQARRRGAIVNN
ASVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVWEV
ANVMVFLASDYASYMTGEVLPVSSQRA

Sequences:

>Translated_267_residues
MTLNTEIPSGPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDVHEKRLAEAVGRLRAETGLQAIHGQ
LCDVSDEAQVRALVAAAEEALGGTDVLINNAGLGGSRRLVDMDDAEWSRVIDISLTGTFRMTRAMLPHMQARRRGAIVNN
ASVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVWEV
ANVMVFLASDYASYMTGEVLPVSSQRA
>Mature_266_residues
TLNTEIPSGPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDVHEKRLAEAVGRLRAETGLQAIHGQL
CDVSDEAQVRALVAAAEEALGGTDVLINNAGLGGSRRLVDMDDAEWSRVIDISLTGTFRMTRAMLPHMQARRRGAIVNNA
SVLGWRAQKEQSHYAAAKAGVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVWEVA
NVMVFLASDYASYMTGEVLPVSSQRA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.258064516129, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI15277342, Length=244, Percent_Identity=29.9180327868852, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=31.4917127071823, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI59889578, Length=183, Percent_Identity=28.9617486338798, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=31.8367346938775, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI66933014, Length=220, Percent_Identity=27.7272727272727, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=29.7709923664122, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=32.4468085106383, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=29.3269230769231, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=29.4820717131474, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=28.3400809716599, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=25.9842519685039, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4503817, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4503301, Length=197, Percent_Identity=27.4111675126904, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40254986, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI83715985, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31542939, Length=189, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI7657478, Length=224, Percent_Identity=29.9107142857143, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI31543615, Length=159, Percent_Identity=31.4465408805031, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=29.7979797979798, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=33.596837944664, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=36.2903225806452, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=30.3149606299213, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=30.6451612903226, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=25.2032520325203, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=29.9180327868852, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=28.8, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.171875, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI2367175, Length=240, Percent_Identity=30.4166666666667, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=29.9212598425197, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788459, Length=164, Percent_Identity=29.8780487804878, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.3478260869565, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=31.9838056680162, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=28.6274509803922, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=31.8725099601594, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=27.710843373494, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=32.0855614973262, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=29.3650793650794, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=252, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=27.0588235294118, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=26.5873015873016, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=27.4193548387097, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=27.0916334661355, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=251, Percent_Identity=26.6932270916335, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=26.3565891472868, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=28.3524904214559, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=26.7441860465116, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=26.3358778625954, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=178, Percent_Identity=26.9662921348315, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=27.734375, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=254, Percent_Identity=25.5905511811024, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=214, Percent_Identity=31.7757009345794, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=187, Percent_Identity=28.3422459893048, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=202, Percent_Identity=28.7128712871287, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.5873015873016, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=198, Percent_Identity=30.3030303030303, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=27.4111675126904, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=221, Percent_Identity=28.5067873303167, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=30.1020408163265, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=224, Percent_Identity=25, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.0080971659919, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=31.7460317460317, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=32.3886639676113, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=30.5220883534137, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=32.2834645669291, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=31.4516129032258, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=31.413612565445, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=27.8225806451613, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357673, Length=200, Percent_Identity=29.5, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17737361, Length=217, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665247, Length=197, Percent_Identity=27.9187817258883, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221331216, Length=211, Percent_Identity=26.5402843601896, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28574402, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584744, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=166, Percent_Identity=30.1204819277108, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665243, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331218, Length=211, Percent_Identity=27.0142180094787, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581726, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649181, Length=216, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28401; Mature: 28270

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNTEIPSGPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDVHEKR
CCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHH
LAEAVGRLRAETGLQAIHGQLCDVSDEAQVRALVAAAEEALGGTDVLINNAGLGGSRRLV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEE
DMDDAEWSRVIDISLTGTFRMTRAMLPHMQARRRGAIVNNASVLGWRAQKEQSHYAAAKA
ECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEECCCEEEEEEHHHHHHHHHHHHH
GVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVWEV
HHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ANVMVFLASDYASYMTGEVLPVSSQRA
HHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
TLNTEIPSGPAYVPGHQLLAGKSVLITAAAGAGIGFAAARRCAEEGCRALMISDVHEKR
CCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHH
LAEAVGRLRAETGLQAIHGQLCDVSDEAQVRALVAAAEEALGGTDVLINNAGLGGSRRLV
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEE
DMDDAEWSRVIDISLTGTFRMTRAMLPHMQARRRGAIVNNASVLGWRAQKEQSHYAAAKA
ECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCEECCCEEEEEEHHHHHHHHHHHHH
GVMALTRCSAMEAAEFGVRINAVAPSIALHDFLKKSAPADLLRQLSEREAFGRAAEVWEV
HHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ANVMVFLASDYASYMTGEVLPVSSQRA
HHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]