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The map label for this gene is paaG [C]

Identifier: 116694608

GI number: 116694608

Start: 731393

End: 732280

Strand: Direct

Name: paaG [C]

Synonym: H16_B0657

Alternate gene names: 116694608

Gene position: 731393-732280 (Clockwise)

Preceding gene: 116694607

Following gene: 116694609

Centisome position: 25.11

GC content: 66.44

Gene sequence:

>888_bases
ATGACAACGCCAGCTACCGAAGCCATCAGCCTTGGCCCCAATGCCGAGGTGCTCTACCAGGTCGCGGACGGCATTGCCAC
CGTGACCATGAACCGGCCGCAGTTCCACAACGCGCAGAACTCAAAGATGACCTACGCGCTGGACGAGGCCTACCGGCGCG
CCGCCGCGGACGACGCGGTCAAGGTGATCGTGCTGCGCGGTGCTGGCAAGCATTTCTCGGCCGGGCACGACATCGGCACG
CCGGGGCGCGACATCAACGAGTCGTTCGAGCGTGCCTCGCTCTGGTATGACCATGTCAACAAGCCGGGCGGCGAGTTTCT
CTATGCCCGCGAGCAGGAGGTCTACCTGGGCATGTGCCGGCGCTGGCGCGAGCTGCCCAAGCCGACCATCGCCATGGTGC
ATGGCGCCTGCATCGCCGGCGGGTTGATGCTGGCATGGGTATGCGACCTGATCGTGGCGTCGGACGATGCCTTCTTTGCC
GATCCGGTGGTGCGCATGGGCATTCCCGGCGTCGAGTACTTCGCGCATCCCTACGAGCTGCATCCGCGCATCGCCAAGGA
GTTCCTGTTCCTGGGCGAGCGCATGGGCGCCGAACGCGCCGAGCGCATGGGCATGGTCAACCGCGTGGTGCCGCGCGACG
CGCTGGAAGACACCGTCTACGGCATGGCCGCCAAGGTCGCGCAGATGCCGCGGCTGGGCCTGACGCTGACCAAGCAGGCG
GTCAACCATGTGGAAGACCTGCAGGGCAAGCGCACCGCGATGGATGCGGTGTTTGCCTGGCACCACTTCGCCCATGCGCA
CAACGAGCTGGTCAGCGGCGACAAGCTCGGCGGCTATGACGCGCGCGCCATGGCCGCTTCGCAACGCACCGGCGAGGACA
AGGCATGA

Upstream 100 bases:

>100_bases
CCGACACCGGAAGAGCTGCGGCTGATCGCCCAGCTTGATCCGCACAACCTGCGCGCGGCCATCGTGCGCGGCAATCCTTC
CGGACGCGTGTGAGGCCGAC

Downstream 100 bases:

>100_bases
GCCCCGCGAGCCTGCACACCGTGCTGTGCGACCTGCTGGGCTGCCGCTACCCCATCGTGCAGACGGCGATGGGCTGGGTG
GCGGATGCGAAGCTGGTCGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTTPATEAISLGPNAEVLYQVADGIATVTMNRPQFHNAQNSKMTYALDEAYRRAAADDAVKVIVLRGAGKHFSAGHDIGT
PGRDINESFERASLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFA
DPVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMGAERAERMGMVNRVVPRDALEDTVYGMAAKVAQMPRLGLTLTKQA
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELVSGDKLGGYDARAMAASQRTGEDKA

Sequences:

>Translated_295_residues
MTTPATEAISLGPNAEVLYQVADGIATVTMNRPQFHNAQNSKMTYALDEAYRRAAADDAVKVIVLRGAGKHFSAGHDIGT
PGRDINESFERASLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFA
DPVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMGAERAERMGMVNRVVPRDALEDTVYGMAAKVAQMPRLGLTLTKQA
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELVSGDKLGGYDARAMAASQRTGEDKA
>Mature_294_residues
TTPATEAISLGPNAEVLYQVADGIATVTMNRPQFHNAQNSKMTYALDEAYRRAAADDAVKVIVLRGAGKHFSAGHDIGTP
GRDINESFERASLWYDHVNKPGGEFLYAREQEVYLGMCRRWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFAD
PVVRMGIPGVEYFAHPYELHPRIAKEFLFLGERMGAERAERMGMVNRVVPRDALEDTVYGMAAKVAQMPRLGLTLTKQAV
NHVEDLQGKRTAMDAVFAWHHFAHAHNELVSGDKLGGYDARAMAASQRTGEDKA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI260275230, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI260274832, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI31542718, Length=225, Percent_Identity=30.6666666666667, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=27.710843373494, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI70995211, Length=252, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1787660, Length=242, Percent_Identity=30.9917355371901, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788597, Length=231, Percent_Identity=32.9004329004329, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI221142681, Length=233, Percent_Identity=32.618025751073, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787659, Length=235, Percent_Identity=27.6595744680851, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082183, Length=215, Percent_Identity=27.4418604651163, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145438, Length=224, Percent_Identity=29.9107142857143, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=276, Percent_Identity=24.6376811594203, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=230, Percent_Identity=27.3913043478261, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=253, Percent_Identity=24.5059288537549, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=226, Percent_Identity=25.2212389380531, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357171, Length=240, Percent_Identity=28.3333333333333, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=30, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=30, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24650670, Length=233, Percent_Identity=31.3304721030043, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653139, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=27.1493212669683, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 32545; Mature: 32414

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPATEAISLGPNAEVLYQVADGIATVTMNRPQFHNAQNSKMTYALDEAYRRAAADDAV
CCCCCCCCEECCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCCCCE
KVIVLRGAGKHFSAGHDIGTPGRDINESFERASLWYDHVNKPGGEFLYAREQEVYLGMCR
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
RWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFADPVVRMGIPGVEYFAHPYEL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCHHHHCCCHHC
HPRIAKEFLFLGERMGAERAERMGMVNRVVPRDALEDTVYGMAAKVAQMPRLGLTLTKQA
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELVSGDKLGGYDARAMAASQRTGEDKA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTPATEAISLGPNAEVLYQVADGIATVTMNRPQFHNAQNSKMTYALDEAYRRAAADDAV
CCCCCCCEECCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHCCCCE
KVIVLRGAGKHFSAGHDIGTPGRDINESFERASLWYDHVNKPGGEFLYAREQEVYLGMCR
EEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHH
RWRELPKPTIAMVHGACIAGGLMLAWVCDLIVASDDAFFADPVVRMGIPGVEYFAHPYEL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCHHHHCCCHHC
HPRIAKEFLFLGERMGAERAERMGMVNRVVPRDALEDTVYGMAAKVAQMPRLGLTLTKQA
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VNHVEDLQGKRTAMDAVFAWHHFAHAHNELVSGDKLGGYDARAMAASQRTGEDKA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA