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The map label for this gene is degU [H]

Identifier: 116694572

GI number: 116694572

Start: 693060

End: 693767

Strand: Direct

Name: degU [H]

Synonym: H16_B0621

Alternate gene names: 116694572

Gene position: 693060-693767 (Clockwise)

Preceding gene: 116694571

Following gene: 116694573

Centisome position: 23.8

GC content: 62.85

Gene sequence:

>708_bases
ATGAGCCAACCATTGACTGACACCGGCGAATCGGTGTTGCCCGCTCCCTTGCTGGTCGTCGAGGACGAGCCACTGATGCA
GACCAGGCTACGCACGATCCTGGCCACGCTCGGCTATGCCGAGGAGGCCTTGTGGTTTGCCGGCAGCCTCGCCGACGCCA
ATGCGCTGCTAACCGCCCAGCCATTTGCGATGGTGCTGGTTGACGTCGGGTTGCCCGACGGCAATGGCATCGACCTCATT
CGCGCGTTGCACGAGCGCGATCCTGCCTTGCCAACTCTGGTAATCTCGACCTGGAACACGGAGCGCGTCATCGTGAGCGC
GCTGCAGGCGGGTGCCACCGGTTACCTGCTCAAGGAGCGCGACGACCTCGAGATTTCCTTGTCGATCCGCAGTGCGCTGC
GCGGCGGAGCGCCGATCGATCCTTTCGTTGCCAGGCACATCCTCGATCTGGTCGCCACGACGGCACCATTGCCAGGCGGG
GCGCAAATTCATGCGCGCCGATTGGTCGGCGCGTCGCCGCTGAGCGCACGGGAAATCGAAATCCTCTCGCTGGTCGGCAA
GGGCCTGACCAATCGGGAGATCGCGGATTTGCTGTCCTTGTCCAGACTGACGGTCGAATGCCACATCAGGAACATATACA
AGAAGTTGGCCGTCCACTCCCGCACGCAGGCCGTTTTCGAAGCGCGTGCGCATGGCTTGTTGCGCTGA

Upstream 100 bases:

>100_bases
GGATGCCCCTCACGGCCGATTTCTGTCAGCCTGGCGTGATCCGGAGATCGGCCAGTTCCGGTGGTACAGCTAAACTCTGG
CCGTGACCGCACCGTACCCA

Downstream 100 bases:

>100_bases
TCTTGGGCGCCACGCTCCTCGCCGGCGCTGCAAACGCGCAGGAAGGGCCGGGCGCCACCGCCTTTACCCGCATAGAGGCT
GCCCGATCGACCTGGCAGGG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSQPLTDTGESVLPAPLLVVEDEPLMQTRLRTILATLGYAEEALWFAGSLADANALLTAQPFAMVLVDVGLPDGNGIDLI
RALHERDPALPTLVISTWNTERVIVSALQAGATGYLLKERDDLEISLSIRSALRGGAPIDPFVARHILDLVATTAPLPGG
AQIHARRLVGASPLSAREIEILSLVGKGLTNREIADLLSLSRLTVECHIRNIYKKLAVHSRTQAVFEARAHGLLR

Sequences:

>Translated_235_residues
MSQPLTDTGESVLPAPLLVVEDEPLMQTRLRTILATLGYAEEALWFAGSLADANALLTAQPFAMVLVDVGLPDGNGIDLI
RALHERDPALPTLVISTWNTERVIVSALQAGATGYLLKERDDLEISLSIRSALRGGAPIDPFVARHILDLVATTAPLPGG
AQIHARRLVGASPLSAREIEILSLVGKGLTNREIADLLSLSRLTVECHIRNIYKKLAVHSRTQAVFEARAHGLLR
>Mature_234_residues
SQPLTDTGESVLPAPLLVVEDEPLMQTRLRTILATLGYAEEALWFAGSLADANALLTAQPFAMVLVDVGLPDGNGIDLIR
ALHERDPALPTLVISTWNTERVIVSALQAGATGYLLKERDDLEISLSIRSALRGGAPIDPFVARHILDLVATTAPLPGGA
QIHARRLVGASPLSAREIEILSLVGKGLTNREIADLLSLSRLTVECHIRNIYKKLAVHSRTQAVFEARAHGLLR

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=216, Percent_Identity=28.2407407407407, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786747, Length=178, Percent_Identity=27.5280898876405, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788222, Length=221, Percent_Identity=28.5067873303167, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25310; Mature: 25178

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPLTDTGESVLPAPLLVVEDEPLMQTRLRTILATLGYAEEALWFAGSLADANALLTAQ
CCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECC
PFAMVLVDVGLPDGNGIDLIRALHERDPALPTLVISTWNTERVIVSALQAGATGYLLKER
CCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECC
DDLEISLSIRSALRGGAPIDPFVARHILDLVATTAPLPGGAQIHARRLVGASPLSAREIE
CCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHH
ILSLVGKGLTNREIADLLSLSRLTVECHIRNIYKKLAVHSRTQAVFEARAHGLLR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQPLTDTGESVLPAPLLVVEDEPLMQTRLRTILATLGYAEEALWFAGSLADANALLTAQ
CCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECC
PFAMVLVDVGLPDGNGIDLIRALHERDPALPTLVISTWNTERVIVSALQAGATGYLLKER
CCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEECC
DDLEISLSIRSALRGGAPIDPFVARHILDLVATTAPLPGGAQIHARRLVGASPLSAREIE
CCCEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHH
ILSLVGKGLTNREIADLLSLSRLTVECHIRNIYKKLAVHSRTQAVFEARAHGLLR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]