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The map label for this gene is hdfR [H]

Identifier: 116694529

GI number: 116694529

Start: 648755

End: 649615

Strand: Direct

Name: hdfR [H]

Synonym: H16_B0578

Alternate gene names: 116694529

Gene position: 648755-649615 (Clockwise)

Preceding gene: 116694526

Following gene: 116694531

Centisome position: 22.27

GC content: 66.67

Gene sequence:

>861_bases
ATGGACATCAATCTCGCCCGCACCTTCCTGCAAGTCGTCCGCACCGGCAGCCTGCTGGCCGCGGCTGACAAGCTGCATGT
CACCCAGACCGCCGTGACCGCGCGCATCAAGAGCCTGGAATCGCAGCTCAACTGCCGCCTGTTCGAGCGCAACAAGGCGG
GCGCACGGCTGACGCCCGATGGTCAGCGCTTTCTCGGCTACGCCAGCCAGCTGGTGCAGACCTGGGAGGCGGCCTGCCGC
GAGCTGCCGTTGCCGGCCGGGCTGGCCAGCCTGTTTCGTTTCGGTACGGAAATCAGCCTGGGCAACCCGCTGGTGCTGCT
GTGGACCACGCGCCTGCGCCAACTGATGCCGGCGCAGGCGGTGCGGGCGGAAGTGGGGGAAGGGGCGGAGCTGCAGCGCA
AGCTGCAGTCAGGCACGCTGGATGCGGCGCTGGTCTACCAGCCGGAGTACGCGCCCGGCATGCATGTCGAGGCGCTGATG
GAAGAGAAGCTGATCCTGATCCGCTCGACGCAGCGCGACGGCGGCTATGTCTATATCGACTGGGGACCGGAATTCCGCTG
CCAGCATGACAGCGCGCTGCCGGAGCATGCGCGCGCCTCGCTGTACTTCAACCTGGGGCCGCTGGCGCTGCAGTACATCC
TGCAGTTCGGTGGCAGTGGGTATTTCCGGACACGCGTGGTGCAGAGCTACCTGGACAGCGGGGTGCTGGCGCGCGTGGAA
GGCGCGTCAGAGTTCTCTTATCCGGTATTCCTCGTCTGCGCCAGGACCCCCGCAGGGGCGTCGCAGGATGCCGTGCGCAT
CCTGCGTGACATCGTGCGCGAAGAATCCGACTGGTCGCAGCGCTGGGATTTCCCGCAATAG

Upstream 100 bases:

>100_bases
AGCACCATCCAATCAGAAGTACGTCTGCGTGTGTACGTCCATAATTCTCAATCTCGTCTGTCATTACCTACAATTCGTCA
CACTGGTAATTCCCCGCCCA

Downstream 100 bases:

>100_bases
CGCAAAGCGGTCAGATCCGGACCGGCACCAGTTGGCCCATCGGGCCGGGCACGGCCACCAGGCGCCATTGCCGCACGCGC
CCCACCCGGCGGCCGCGCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MDINLARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFERNKAGARLTPDGQRFLGYASQLVQTWEAACR
ELPLPAGLASLFRFGTEISLGNPLVLLWTTRLRQLMPAQAVRAEVGEGAELQRKLQSGTLDAALVYQPEYAPGMHVEALM
EEKLILIRSTQRDGGYVYIDWGPEFRCQHDSALPEHARASLYFNLGPLALQYILQFGGSGYFRTRVVQSYLDSGVLARVE
GASEFSYPVFLVCARTPAGASQDAVRILRDIVREESDWSQRWDFPQ

Sequences:

>Translated_286_residues
MDINLARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFERNKAGARLTPDGQRFLGYASQLVQTWEAACR
ELPLPAGLASLFRFGTEISLGNPLVLLWTTRLRQLMPAQAVRAEVGEGAELQRKLQSGTLDAALVYQPEYAPGMHVEALM
EEKLILIRSTQRDGGYVYIDWGPEFRCQHDSALPEHARASLYFNLGPLALQYILQFGGSGYFRTRVVQSYLDSGVLARVE
GASEFSYPVFLVCARTPAGASQDAVRILRDIVREESDWSQRWDFPQ
>Mature_286_residues
MDINLARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFERNKAGARLTPDGQRFLGYASQLVQTWEAACR
ELPLPAGLASLFRFGTEISLGNPLVLLWTTRLRQLMPAQAVRAEVGEGAELQRKLQSGTLDAALVYQPEYAPGMHVEALM
EEKLILIRSTQRDGGYVYIDWGPEFRCQHDSALPEHARASLYFNLGPLALQYILQFGGSGYFRTRVVQSYLDSGVLARVE
GASEFSYPVFLVCARTPAGASQDAVRILRDIVREESDWSQRWDFPQ

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=281, Percent_Identity=28.1138790035587, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787601, Length=169, Percent_Identity=28.9940828402367, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=195, Percent_Identity=28.7179487179487, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31938; Mature: 31938

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINLARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFERNKAGARLTPD
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCC
GQRFLGYASQLVQTWEAACRELPLPAGLASLFRFGTEISLGNPLVLLWTTRLRQLMPAQA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHCCHHH
VRAEVGEGAELQRKLQSGTLDAALVYQPEYAPGMHVEALMEEKLILIRSTQRDGGYVYID
HHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEEE
WGPEFRCQHDSALPEHARASLYFNLGPLALQYILQFGGSGYFRTRVVQSYLDSGVLARVE
CCCCCCCCCCCCCCCHHCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEC
GASEFSYPVFLVCARTPAGASQDAVRILRDIVREESDWSQRWDFPQ
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure
MDINLARTFLQVVRTGSLLAAADKLHVTQTAVTARIKSLESQLNCRLFERNKAGARLTPD
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCC
GQRFLGYASQLVQTWEAACRELPLPAGLASLFRFGTEISLGNPLVLLWTTRLRQLMPAQA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHCCHHH
VRAEVGEGAELQRKLQSGTLDAALVYQPEYAPGMHVEALMEEKLILIRSTQRDGGYVYID
HHHHCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCEEEEEECCCCCCEEEEE
WGPEFRCQHDSALPEHARASLYFNLGPLALQYILQFGGSGYFRTRVVQSYLDSGVLARVE
CCCCCCCCCCCCCCCHHCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEC
GASEFSYPVFLVCARTPAGASQDAVRILRDIVREESDWSQRWDFPQ
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA