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The map label for this gene is mmgC [H]

Identifier: 116694531

GI number: 116694531

Start: 650108

End: 651265

Strand: Direct

Name: mmgC [H]

Synonym: H16_B0580

Alternate gene names: 116694531

Gene position: 650108-651265 (Clockwise)

Preceding gene: 116694529

Following gene: 116694532

Centisome position: 22.32

GC content: 67.01

Gene sequence:

>1158_bases
ATGCAACGCCTGATCTTCGAAGCCGAACACGACGCCTTCCGCGAATCCGCCCGCCGCTTCTACCAGCGCGAGGTGGGGCC
GCACGGCGAGCGCTGGCGCGAACAGGGCTGCGTGGACCGCGAAGTGTTCCGCAAGGCCGGCGAGCAGGGCTACCTGCTGA
TGTGGGCCGACGAGAAATACGGCGGCGCCGGCGTGGAGGATTTCCGCTATGAGCAGATCCTGATCGAAGAGAATGCGCGC
CACGGCGACTCGGGCTTTTTCGGCACGCTGCACTCGCGGCTGGTGGCGCCGTATATCGGCCGCATCGGCAACGAGGAACA
ACGCCAGCGCCTGCTGCCGGCGGCCGCGCGCGGCGAGTCGATCTTTGCCATTGCCATGACCGAGCCGCAGGCGGGATCCG
ACCTGGCCGGCATGCGCACGCGTGCCGAGGACCACGGCGACCACTGGGTGCTGAACGGCGCCAAGACCTATATCTCGAAC
GGCCAGCTGGCCGACTACGTGGTGGTGGTCGCGCGCACTGATCCGGAGCGCAGCCATGGCCTTGGCCTCTTTATCGTCGA
GCGCGGCATGCCCGGCTTCGAGCGCGGGCGCAAGCTGCGCAAGATGGGCCTGCACTCGCAGGACACCTCGGAGCTGTTCT
TCGACAACGTCAAGGTGCCCAAGGCCAACGTGCTGGGCGAGCCCGGCCAGGGCTTCCGCTACCTGACGCGCCACCTGGCC
GAAGAGCGGCTGATTGGCGCCTGCGGCTACATGGCGTCGGCGCAGGTGGCGTTCGACCTCACGCTGGACTATGTCAAGGA
GCGCAAGGCCTTCGGCCGGGCCATCGGCACGTTCCAGAACTCGCGCTTCAAGCTTGCCGAACTGCGGGCGCAGCTGGATG
CGCTGCAGACCTTCGTCGACCAGTGCGTGCTGCAGCACAACGCAGGCACGCTGACCGTGGAGACGGCGGCGTCGGCCAAG
CTGCTCACGTCGGAACTGCAGGGACGCATGGTCGACGAGGGCGTGCAGCTGCACGGTGGCGCCGGCTATATGGAGGAGTA
CCGCATCTGCCGCATGTACACCGACGCGCGCATCTCGCGCATCTACGCCGGCAGCAGCGAGATCATGAAGGAGATCATCG
GCCGCAGCCTGGGGCTGGATGACCGCATGAAGGGGTAA

Upstream 100 bases:

>100_bases
TTCGGCTGCGGGAGGAAAAATCATCCTTTCCGACGAATCTCATAGACGCTGCACGGCAGACACTCAGCCGGTCACTCTCA
AAAACACCAGGAGACCCCGC

Downstream 100 bases:

>100_bases
GCCGCCTGGCAGTACAGACGGCACGGCCGGCAACGGCCGTGCCGTTTTTCATGGTTTTCCGATTGGCTAGGGTTTTCGCG
CAGTTAAAGGCTTTTGTCAG

Product: Acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQRLIFEAEHDAFRESARRFYQREVGPHGERWREQGCVDREVFRKAGEQGYLLMWADEKYGGAGVEDFRYEQILIEENAR
HGDSGFFGTLHSRLVAPYIGRIGNEEQRQRLLPAAARGESIFAIAMTEPQAGSDLAGMRTRAEDHGDHWVLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERGMPGFERGRKLRKMGLHSQDTSELFFDNVKVPKANVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDLTLDYVKERKAFGRAIGTFQNSRFKLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRMVDEGVQLHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRMKG

Sequences:

>Translated_385_residues
MQRLIFEAEHDAFRESARRFYQREVGPHGERWREQGCVDREVFRKAGEQGYLLMWADEKYGGAGVEDFRYEQILIEENAR
HGDSGFFGTLHSRLVAPYIGRIGNEEQRQRLLPAAARGESIFAIAMTEPQAGSDLAGMRTRAEDHGDHWVLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERGMPGFERGRKLRKMGLHSQDTSELFFDNVKVPKANVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDLTLDYVKERKAFGRAIGTFQNSRFKLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRMVDEGVQLHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRMKG
>Mature_385_residues
MQRLIFEAEHDAFRESARRFYQREVGPHGERWREQGCVDREVFRKAGEQGYLLMWADEKYGGAGVEDFRYEQILIEENAR
HGDSGFFGTLHSRLVAPYIGRIGNEEQRQRLLPAAARGESIFAIAMTEPQAGSDLAGMRTRAEDHGDHWVLNGAKTYISN
GQLADYVVVVARTDPERSHGLGLFIVERGMPGFERGRKLRKMGLHSQDTSELFFDNVKVPKANVLGEPGQGFRYLTRHLA
EERLIGACGYMASAQVAFDLTLDYVKERKAFGRAIGTFQNSRFKLAELRAQLDALQTFVDQCVLQHNAGTLTVETAASAK
LLTSELQGRMVDEGVQLHGGAGYMEEYRICRMYTDARISRIYAGSSEIMKEIIGRSLGLDDRMKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=46.9816272965879, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=34.7480106100796, Blast_Score=231, Evalue=7e-61,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=36.3372093023256, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=32.3529411764706, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=31.989247311828, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=31.7333333333333, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=31.3829787234043, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=31.3829787234043, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI76496475, Length=372, Percent_Identity=31.4516129032258, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI21361497, Length=381, Percent_Identity=30.9711286089239, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4557235, Length=372, Percent_Identity=31.4516129032258, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=29.7872340425532, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI7669494, Length=350, Percent_Identity=30.2857142857143, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI211971008, Length=365, Percent_Identity=25.2054794520548, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI48976061, Length=365, Percent_Identity=25.2054794520548, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI38505218, Length=320, Percent_Identity=24.0625, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081958, Length=360, Percent_Identity=30.2777777777778, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1786223, Length=279, Percent_Identity=29.7491039426523, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI87082384, Length=279, Percent_Identity=27.2401433691756, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=37.4331550802139, Blast_Score=244, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=33.5978835978836, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=32.7956989247312, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17534899, Length=366, Percent_Identity=31.6939890710383, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=31.6939890710383, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=30.1587301587302, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=382, Percent_Identity=30.8900523560209, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17506239, Length=366, Percent_Identity=30.8743169398907, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=29.287598944591, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI71985184, Length=279, Percent_Identity=35.1254480286738, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=33.4532374100719, Blast_Score=160, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71982178, Length=267, Percent_Identity=32.9588014981273, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=204, Percent_Identity=36.7647058823529, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17534353, Length=368, Percent_Identity=29.3478260869565, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=34.6666666666667, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=26.1410788381743, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=289, Percent_Identity=26.643598615917, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=33.8582677165354, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=31.0810810810811, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=32.6145552560647, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=30.6233062330623, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=30.3763440860215, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281363737, Length=335, Percent_Identity=29.8507462686567, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=28.3068783068783, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43300; Mature: 43300

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLIFEAEHDAFRESARRFYQREVGPHGERWREQGCVDREVFRKAGEQGYLLMWADEKY
CCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GGAGVEDFRYEQILIEENARHGDSGFFGTLHSRLVAPYIGRIGNEEQRQRLLPAAARGES
CCCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCE
IFAIAMTEPQAGSDLAGMRTRAEDHGDHWVLNGAKTYISNGQLADYVVVVARTDPERSHG
EEEEEEECCCCCCCHHHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEEEEECCCCCCCC
LGLFIVERGMPGFERGRKLRKMGLHSQDTSELFFDNVKVPKANVLGEPGQGFRYLTRHLA
CEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHH
EERLIGACGYMASAQVAFDLTLDYVKERKAFGRAIGTFQNSRFKLAELRAQLDALQTFVD
HHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QCVLQHNAGTLTVETAASAKLLTSELQGRMVDEGVQLHGGAGYMEEYRICRMYTDARISR
HHHHHCCCCEEEEECCHHHHHHHHHHHCCCHHCCEEECCCCCHHHHHHHHHHHHHHHHHH
IYAGSSEIMKEIIGRSLGLDDRMKG
HCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQRLIFEAEHDAFRESARRFYQREVGPHGERWREQGCVDREVFRKAGEQGYLLMWADEKY
CCCCEEECHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GGAGVEDFRYEQILIEENARHGDSGFFGTLHSRLVAPYIGRIGNEEQRQRLLPAAARGES
CCCCCCHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCE
IFAIAMTEPQAGSDLAGMRTRAEDHGDHWVLNGAKTYISNGQLADYVVVVARTDPERSHG
EEEEEEECCCCCCCHHHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEEEEECCCCCCCC
LGLFIVERGMPGFERGRKLRKMGLHSQDTSELFFDNVKVPKANVLGEPGQGFRYLTRHLA
CEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHH
EERLIGACGYMASAQVAFDLTLDYVKERKAFGRAIGTFQNSRFKLAELRAQLDALQTFVD
HHHHHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QCVLQHNAGTLTVETAASAKLLTSELQGRMVDEGVQLHGGAGYMEEYRICRMYTDARISR
HHHHHCCCCEEEEECCHHHHHHHHHHHCCCHHCCEEECCCCCHHHHHHHHHHHHHHHHHH
IYAGSSEIMKEIIGRSLGLDDRMKG
HCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]