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The map label for this gene is 116694523

Identifier: 116694523

GI number: 116694523

Start: 644034

End: 645365

Strand: Direct

Name: 116694523

Synonym: H16_B0572

Alternate gene names: NA

Gene position: 644034-645365 (Clockwise)

Preceding gene: 116694522

Following gene: 116694524

Centisome position: 22.11

GC content: 69.44

Gene sequence:

>1332_bases
ATGCCGATGCCCATCACCTTTTCCCTGTTGCGTGTCGTTCTTTTGGCGGGCGCCACCGCTGCGCTCGCCGCCTGCGGTGA
AACGGCCAAGCTGCCTTCCGAAGCGGGCTTTGGCCCCACGCCGCAGCTGCCGCCACCCAACCAGACCGCGATCCCCACCG
TCAAGATCGCGCCGGCCATCGGCTGGGCCGCGGGCCAGCGCCCGGTGCCGGCCGCAGGCATGGCGGTGACGGCCTTCGCC
GACAAGCTGGACCATCCGCGCTGGGTCTATGTGCTGCCCAACGGCGACGTGCTGGTGGCCGAGAGCAATGCCCCGCCCAA
GCCCGACGACGGCAAGGGCTTCCGCGGCTGGATCATGAAGAAGGTGATGAAGCGCGCGGGCGCCGGCACCCCCAGCGCCA
ACCGCATCACGCTGCTGCGCGACACCAACGGCGACGGCGTCGCCGACCAGCGCTCGGTGTTCCTAAAGGACCTGAACTCG
CCGTTCGGCATGGCCCTGGTCGGCAACGACTTCTACGTAGCCGCCACCGACGCGGTGCTGCGCTTCCCGTACCAGCCCGG
ACAGACCCGGATTACGGCCGCGCCCCAGAAGGTGGTGGACCTGCCCGGCGGGCCGCTCAACCATCACTGGACCAAGAGCC
TGATCGCCAGCCGCGACGGCAGCAAGCTGTACGTGACGGTGGGCTCCAACAGCAACGTGGGCGAGCACGGCATGGACAAG
GAGGTCGGCCGCGCCGCCATCTGGGAGGTCGACCCGCAGGCCGGCACGCACCGGATCTTTGCCAGCGGCCTGCGCAATCC
CAACGGCATGGCGTGGGAACCGGTCACCGGCATGCTCTGGACCGCCGTCAACGAGCGCGATGAAATCGGCAGCGACCTGG
TGCCGGACTACATCACCTCGGTGCGCGACGGCGGCTTCTATGGCTGGCCCTACAGCTACTACGGCCAGCATGTCGACGCA
CGCGTGAAGCCGCCGGCGCCGGACCTGGTGGCCAGGGCCATCGTGCCGGACTATGCCGTGGGGGCGCACACCGCATCGCT
CGGGCTGGCCGCCGCCGGCGGCAACAACCTGCCGGCGCGCTTCAGCGAAGGCATGTTCGTGGGCCTGCACGGTTCGTGGA
ACCGCAGGCCGCTGGCGGGCTACAAGGTGATCTTCGTGCCGTTCAGCAAGGGCCGGCCCAACGGCGCGCCGTTCGACGTG
CTGACCGGCTTTCTCGATGAGGACGGCAACGCGCGCGGGCGGCCGGTGGGCGTGGCGATCGACAAGCAAGGCGGTTTGCT
GGTGGCCGACGATGTCGGCAATACCGTGTGGCGGGTCAGCGGCGCGAAGTAG

Upstream 100 bases:

>100_bases
TACACGGCGGCCTCCCCGGCGCCTACAGAGGGGCGGGCGGCACGCATCCTATAGTCCAGGAACAGGCGCATCGCCCTGCG
TTGCCTGAGGAGCCCGGACC

Downstream 100 bases:

>100_bases
GCGGGCCAGGGCGCGGCAGCGGCGGCACCGCACCGCTAGAATGACGGCGTCCCCACACGCCGAGCCCGCTGCCGTCCATG
TCTCTCACGGTCTTCGCTGT

Product: glucose/sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPMPITFSLLRVVLLAGATAALAACGETAKLPSEAGFGPTPQLPPPNQTAIPTVKIAPAIGWAAGQRPVPAAGMAVTAFA
DKLDHPRWVYVLPNGDVLVAESNAPPKPDDGKGFRGWIMKKVMKRAGAGTPSANRITLLRDTNGDGVADQRSVFLKDLNS
PFGMALVGNDFYVAATDAVLRFPYQPGQTRITAAPQKVVDLPGGPLNHHWTKSLIASRDGSKLYVTVGSNSNVGEHGMDK
EVGRAAIWEVDPQAGTHRIFASGLRNPNGMAWEPVTGMLWTAVNERDEIGSDLVPDYITSVRDGGFYGWPYSYYGQHVDA
RVKPPAPDLVARAIVPDYAVGAHTASLGLAAAGGNNLPARFSEGMFVGLHGSWNRRPLAGYKVIFVPFSKGRPNGAPFDV
LTGFLDEDGNARGRPVGVAIDKQGGLLVADDVGNTVWRVSGAK

Sequences:

>Translated_443_residues
MPMPITFSLLRVVLLAGATAALAACGETAKLPSEAGFGPTPQLPPPNQTAIPTVKIAPAIGWAAGQRPVPAAGMAVTAFA
DKLDHPRWVYVLPNGDVLVAESNAPPKPDDGKGFRGWIMKKVMKRAGAGTPSANRITLLRDTNGDGVADQRSVFLKDLNS
PFGMALVGNDFYVAATDAVLRFPYQPGQTRITAAPQKVVDLPGGPLNHHWTKSLIASRDGSKLYVTVGSNSNVGEHGMDK
EVGRAAIWEVDPQAGTHRIFASGLRNPNGMAWEPVTGMLWTAVNERDEIGSDLVPDYITSVRDGGFYGWPYSYYGQHVDA
RVKPPAPDLVARAIVPDYAVGAHTASLGLAAAGGNNLPARFSEGMFVGLHGSWNRRPLAGYKVIFVPFSKGRPNGAPFDV
LTGFLDEDGNARGRPVGVAIDKQGGLLVADDVGNTVWRVSGAK
>Mature_442_residues
PMPITFSLLRVVLLAGATAALAACGETAKLPSEAGFGPTPQLPPPNQTAIPTVKIAPAIGWAAGQRPVPAAGMAVTAFAD
KLDHPRWVYVLPNGDVLVAESNAPPKPDDGKGFRGWIMKKVMKRAGAGTPSANRITLLRDTNGDGVADQRSVFLKDLNSP
FGMALVGNDFYVAATDAVLRFPYQPGQTRITAAPQKVVDLPGGPLNHHWTKSLIASRDGSKLYVTVGSNSNVGEHGMDKE
VGRAAIWEVDPQAGTHRIFASGLRNPNGMAWEPVTGMLWTAVNERDEIGSDLVPDYITSVRDGGFYGWPYSYYGQHVDAR
VKPPAPDLVARAIVPDYAVGAHTASLGLAAAGGNNLPARFSEGMFVGLHGSWNRRPLAGYKVIFVPFSKGRPNGAPFDVL
TGFLDEDGNARGRPVGVAIDKQGGLLVADDVGNTVWRVSGAK

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 46901; Mature: 46770

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPITFSLLRVVLLAGATAALAACGETAKLPSEAGFGPTPQLPPPNQTAIPTVKIAPAI
CCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GWAAGQRPVPAAGMAVTAFADKLDHPRWVYVLPNGDVLVAESNAPPKPDDGKGFRGWIMK
CCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHH
KVMKRAGAGTPSANRITLLRDTNGDGVADQRSVFLKDLNSPFGMALVGNDFYVAATDAVL
HHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCEEEEEECEEE
RFPYQPGQTRITAAPQKVVDLPGGPLNHHWTKSLIASRDGSKLYVTVGSNSNVGEHGMDK
ECCCCCCCEEEEECCHHEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
EVGRAAIWEVDPQAGTHRIFASGLRNPNGMAWEPVTGMLWTAVNERDEIGSDLVPDYITS
HHCCEEEEEECCCCCCHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHCCCCCCHHHHHH
VRDGGFYGWPYSYYGQHVDARVKPPAPDLVARAIVPDYAVGAHTASLGLAAAGGNNLPAR
HCCCCEECCCHHHHCCCCCCEECCCCHHHHHHHHCCCCCCCCCHHHCEEEECCCCCCCCC
FSEGMFVGLHGSWNRRPLAGYKVIFVPFSKGRPNGAPFDVLTGFLDEDGNARGRPVGVAI
CCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEE
DKQGGLLVADDVGNTVWRVSGAK
ECCCCEEEEECCCCEEEEEECCC
>Mature Secondary Structure 
PMPITFSLLRVVLLAGATAALAACGETAKLPSEAGFGPTPQLPPPNQTAIPTVKIAPAI
CCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
GWAAGQRPVPAAGMAVTAFADKLDHPRWVYVLPNGDVLVAESNAPPKPDDGKGFRGWIMK
CCCCCCCCCCCCCEEHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHH
KVMKRAGAGTPSANRITLLRDTNGDGVADQRSVFLKDLNSPFGMALVGNDFYVAATDAVL
HHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCEEEEEECEEE
RFPYQPGQTRITAAPQKVVDLPGGPLNHHWTKSLIASRDGSKLYVTVGSNSNVGEHGMDK
ECCCCCCCEEEEECCHHEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
EVGRAAIWEVDPQAGTHRIFASGLRNPNGMAWEPVTGMLWTAVNERDEIGSDLVPDYITS
HHCCEEEEEECCCCCCHHHHHHHCCCCCCCEECCCCCEEEEECCCHHHCCCCCCHHHHHH
VRDGGFYGWPYSYYGQHVDARVKPPAPDLVARAIVPDYAVGAHTASLGLAAAGGNNLPAR
HCCCCEECCCHHHHCCCCCCEECCCCHHHHHHHHCCCCCCCCCHHHCEEEECCCCCCCCC
FSEGMFVGLHGSWNRRPLAGYKVIFVPFSKGRPNGAPFDVLTGFLDEDGNARGRPVGVAI
CCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEE
DKQGGLLVADDVGNTVWRVSGAK
ECCCCEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]