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The map label for this gene is luxQ [H]

Identifier: 116694521

GI number: 116694521

Start: 641281

End: 643086

Strand: Direct

Name: luxQ [H]

Synonym: H16_B0570

Alternate gene names: 116694521

Gene position: 641281-643086 (Clockwise)

Preceding gene: 116694519

Following gene: 116694522

Centisome position: 22.02

GC content: 72.26

Gene sequence:

>1806_bases
ATGACAGCCACAGGCACCGGATTGCCGCCGGCCTGGCAGCCCGGAGATGTGCCGGCGGCGATGGTGGACCTGCTCTACCG
CCAGTCCAACGCGGTCCTGTTTGCCAACTTCGTCATTGCGCTGCCGGTGGTCTATGTGCTGCGTCCCAGCGTGCCGCTGC
CCATGCTGGCCGGCTGGATGGCCGCGGTGTACCTGCTGACCACGCTGCGCATCGGCCTGTCGCGGCGCTACTTCCGGCGC
GACGGCAGCACGCCGCCGCAGGTGTGGGCACGCCGCTTCATGGTGCTGTCCTGGCTGTCCAGCCTGCTGTGGGGCGCCGT
GGGCTCTGCCATCCTGCTGCCGCCCGAGCCGCAGCTGGTGGCGTTCTGCTGCATCGTGCTGGCCGGCATGTCCAGTGGCG
CGATCCCGTCGCTGTCGGCGCATCCGGCCACCTACCGCGGTTCAGTCGCGGCCATGCTGCTGCCGTTCACCATCTATTGC
CTGGTGCAGCAGGGGCCGGTGTATGGCGTCTACGCGGGCTTTGCCGCGTGCCTGCTGTGCGTCAACATCTACTACAGCCA
GGTCACCTATCGCGCGCTGCGCGATGGCGTGACACTGCGCTTCGAGAACGTCGCGCTGATCGGCGAGCTTGAGCGCGAGC
GCGACCGCGTCACCGCCGCGGACCGGGCCAAGACGCGCTTCCTGGCGGCCGCCGGGCACGACCTGCGCCAGCCGGTGTAT
GCCATCGGCCTGCAGGCGGCATCGCTGCTGACTCTGGGCGAGCGCGGCGATGTGGCAGGCGGCCAGGCGCATGCCATCGG
CCACCGGCTGCAAGCCACGCTGGCGCGCATGGACAACCTGCTCGACGGCCTGCTCGACGCCTCGCGCCTGGATGCCGGCG
TGATGCCGGTGCGCCGCCAGCCGCTGCATCTGGCGCGGCTGCTGGCCGAGCTGCGCGACGAGTACGCCGAGCAGGCGTGC
CAGCGCGGCAGCGTGCTGCGGGTGGTGCCGGCGCGCGCGTGGATCGACAGCGATCCGGACCTGCTCAAGCGCATCCTCGA
CAACCTGGTGGCCAATGCGCTGCGCCATGCGCCGCGTGCCAGCATCCTGGTGGGCGCGCGGCGCCGCGGCGATGCCATGG
AGATCCAGGTGATCGACACCGGCCCGGGCATCGCCGCGGCCCAGCAGTCGCGCGTGTTCGACGAATACGCCCAGGTGCCG
GGCCTTGCCATGGCAGGCGACGACCAGGCGGGCGCAAAGGGACTGGGCCTGGGCCTGGCGATCGTGCGGCGCCTGGCGGC
GCTGCTTGGCCACCAGGTGGGCCTGCGTTCCGCACCGGGGCGCGGCTGCGTGTTTTCGGTGCGCGTGCCGCTGGCTGCCG
CCGCGGCGCAGGTGCATCCAGCCACCCCCGCCATTCCCGCGGCCGCTGGCGAGCCGCTCTGCGTGATGCTGGTCGACGAC
GACGCGCAGGTGCTGGGCGCGCTCACCGAACTGCTGTCGCTCTGGGGCCATGTGGTCTACGGCGGGCGCACCGTTGCCGC
AGTGCGCGCTGCGTACCGCGCCGCCAGCCAGGACGGGCCCGCCCCGGTCCACCTGATCCTGGCCGACTACCGGCTGGCCG
AAGGCCTGACCGGCATCGCTGCGGTCGGCATGCTGCGCGCCAGCCTGGGCCGCGCGGTGCCGGCGCTGATCGTCACCGGC
GACACCGCGCCAGACCGGCTGCAGGCGCTGCATGACAGCGGCTTCCCGGTGTTGCACAAGCCGATCCAGGGCGAGGCCTT
GCGCGCGGCCCTGCATCGCGCGGTGCAACTGGCCGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GTTGCACGCCCAACCTGCCCCACGGCCTACCTAGCATGCGCAAGCTTCCGTTGTCCTGTTGCCGTACCGTTTCCTGCCGC
CCGCAACGGGCGCTCGCATC

Downstream 100 bases:

>100_bases
GGCCCTGCGCTGCATGCATGGCAGGAGCGGTTTATGATCGGGCTTTTCCGTTGTCCGGCGCCTTCTTGCGCAGTGCGCAA
GCGCCTGAACCAGGAGCCAG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTATGTGLPPAWQPGDVPAAMVDLLYRQSNAVLFANFVIALPVVYVLRPSVPLPMLAGWMAAVYLLTTLRIGLSRRYFRR
DGSTPPQVWARRFMVLSWLSSLLWGAVGSAILLPPEPQLVAFCCIVLAGMSSGAIPSLSAHPATYRGSVAAMLLPFTIYC
LVQQGPVYGVYAGFAACLLCVNIYYSQVTYRALRDGVTLRFENVALIGELERERDRVTAADRAKTRFLAAAGHDLRQPVY
AIGLQAASLLTLGERGDVAGGQAHAIGHRLQATLARMDNLLDGLLDASRLDAGVMPVRRQPLHLARLLAELRDEYAEQAC
QRGSVLRVVPARAWIDSDPDLLKRILDNLVANALRHAPRASILVGARRRGDAMEIQVIDTGPGIAAAQQSRVFDEYAQVP
GLAMAGDDQAGAKGLGLGLAIVRRLAALLGHQVGLRSAPGRGCVFSVRVPLAAAAAQVHPATPAIPAAAGEPLCVMLVDD
DAQVLGALTELLSLWGHVVYGGRTVAAVRAAYRAASQDGPAPVHLILADYRLAEGLTGIAAVGMLRASLGRAVPALIVTG
DTAPDRLQALHDSGFPVLHKPIQGEALRAALHRAVQLAEAA

Sequences:

>Translated_601_residues
MTATGTGLPPAWQPGDVPAAMVDLLYRQSNAVLFANFVIALPVVYVLRPSVPLPMLAGWMAAVYLLTTLRIGLSRRYFRR
DGSTPPQVWARRFMVLSWLSSLLWGAVGSAILLPPEPQLVAFCCIVLAGMSSGAIPSLSAHPATYRGSVAAMLLPFTIYC
LVQQGPVYGVYAGFAACLLCVNIYYSQVTYRALRDGVTLRFENVALIGELERERDRVTAADRAKTRFLAAAGHDLRQPVY
AIGLQAASLLTLGERGDVAGGQAHAIGHRLQATLARMDNLLDGLLDASRLDAGVMPVRRQPLHLARLLAELRDEYAEQAC
QRGSVLRVVPARAWIDSDPDLLKRILDNLVANALRHAPRASILVGARRRGDAMEIQVIDTGPGIAAAQQSRVFDEYAQVP
GLAMAGDDQAGAKGLGLGLAIVRRLAALLGHQVGLRSAPGRGCVFSVRVPLAAAAAQVHPATPAIPAAAGEPLCVMLVDD
DAQVLGALTELLSLWGHVVYGGRTVAAVRAAYRAASQDGPAPVHLILADYRLAEGLTGIAAVGMLRASLGRAVPALIVTG
DTAPDRLQALHDSGFPVLHKPIQGEALRAALHRAVQLAEAA
>Mature_600_residues
TATGTGLPPAWQPGDVPAAMVDLLYRQSNAVLFANFVIALPVVYVLRPSVPLPMLAGWMAAVYLLTTLRIGLSRRYFRRD
GSTPPQVWARRFMVLSWLSSLLWGAVGSAILLPPEPQLVAFCCIVLAGMSSGAIPSLSAHPATYRGSVAAMLLPFTIYCL
VQQGPVYGVYAGFAACLLCVNIYYSQVTYRALRDGVTLRFENVALIGELERERDRVTAADRAKTRFLAAAGHDLRQPVYA
IGLQAASLLTLGERGDVAGGQAHAIGHRLQATLARMDNLLDGLLDASRLDAGVMPVRRQPLHLARLLAELRDEYAEQACQ
RGSVLRVVPARAWIDSDPDLLKRILDNLVANALRHAPRASILVGARRRGDAMEIQVIDTGPGIAAAQQSRVFDEYAQVPG
LAMAGDDQAGAKGLGLGLAIVRRLAALLGHQVGLRSAPGRGCVFSVRVPLAAAAAQVHPATPAIPAAAGEPLCVMLVDDD
AQVLGALTELLSLWGHVVYGGRTVAAVRAAYRAASQDGPAPVHLILADYRLAEGLTGIAAVGMLRASLGRAVPALIVTGD
TAPDRLQALHDSGFPVLHKPIQGEALRAALHRAVQLAEAA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=399, Percent_Identity=27.0676691729323, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=293, Percent_Identity=25.5972696245734, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI145693157, Length=359, Percent_Identity=25.3481894150418, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=27.7915632754342, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1786912, Length=306, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789149, Length=265, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=307, Percent_Identity=24.4299674267101, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=25.3275109170306, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=28, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=29.3388429752066, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=27.6315789473684, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787894, Length=251, Percent_Identity=25.4980079681275, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63763; Mature: 63632

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATGTGLPPAWQPGDVPAAMVDLLYRQSNAVLFANFVIALPVVYVLRPSVPLPMLAGWM
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
AAVYLLTTLRIGLSRRYFRRDGSTPPQVWARRFMVLSWLSSLLWGAVGSAILLPPEPQLV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AFCCIVLAGMSSGAIPSLSAHPATYRGSVAAMLLPFTIYCLVQQGPVYGVYAGFAACLLC
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VNIYYSQVTYRALRDGVTLRFENVALIGELERERDRVTAADRAKTRFLAAAGHDLRQPVY
HHHHHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHH
AIGLQAASLLTLGERGDVAGGQAHAIGHRLQATLARMDNLLDGLLDASRLDAGVMPVRRQ
HHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLHLARLLAELRDEYAEQACQRGSVLRVVPARAWIDSDPDLLKRILDNLVANALRHAPRA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
SILVGARRRGDAMEIQVIDTGPGIAAAQQSRVFDEYAQVPGLAMAGDDQAGAKGLGLGLA
CEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHH
IVRRLAALLGHQVGLRSAPGRGCVFSVRVPLAAAAAQVHPATPAIPAAAGEPLCVMLVDD
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
DAQVLGALTELLSLWGHVVYGGRTVAAVRAAYRAASQDGPAPVHLILADYRLAEGLTGIA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCHHHHH
AVGMLRASLGRAVPALIVTGDTAPDRLQALHDSGFPVLHKPIQGEALRAALHRAVQLAEA
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
TATGTGLPPAWQPGDVPAAMVDLLYRQSNAVLFANFVIALPVVYVLRPSVPLPMLAGWM
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHH
AAVYLLTTLRIGLSRRYFRRDGSTPPQVWARRFMVLSWLSSLLWGAVGSAILLPPEPQLV
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHH
AFCCIVLAGMSSGAIPSLSAHPATYRGSVAAMLLPFTIYCLVQQGPVYGVYAGFAACLLC
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VNIYYSQVTYRALRDGVTLRFENVALIGELERERDRVTAADRAKTRFLAAAGHDLRQPVY
HHHHHHHHHHHHHHCCCEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHH
AIGLQAASLLTLGERGDVAGGQAHAIGHRLQATLARMDNLLDGLLDASRLDAGVMPVRRQ
HHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLHLARLLAELRDEYAEQACQRGSVLRVVPARAWIDSDPDLLKRILDNLVANALRHAPRA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
SILVGARRRGDAMEIQVIDTGPGIAAAQQSRVFDEYAQVPGLAMAGDDQAGAKGLGLGLA
CEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHH
IVRRLAALLGHQVGLRSAPGRGCVFSVRVPLAAAAAQVHPATPAIPAAAGEPLCVMLVDD
HHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
DAQVLGALTELLSLWGHVVYGGRTVAAVRAAYRAASQDGPAPVHLILADYRLAEGLTGIA
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCHHHHH
AVGMLRASLGRAVPALIVTGDTAPDRLQALHDSGFPVLHKPIQGEALRAALHRAVQLAEA
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA