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The map label for this gene is degU [H]

Identifier: 116694474

GI number: 116694474

Start: 589699

End: 590388

Strand: Direct

Name: degU [H]

Synonym: H16_B0523

Alternate gene names: 116694474

Gene position: 589699-590388 (Clockwise)

Preceding gene: 116694473

Following gene: 116694475

Centisome position: 20.25

GC content: 68.99

Gene sequence:

>690_bases
ATGACAAGAAGTCAAGGCGCCGCAGAGAACAACAACGACGCCAGCATCGACGCCAGCGCGTGCCGCAACTATGCCATCGT
GGTGGATGACCACCCGTTGATGGCGCGCGGCATTGCCGGCTACCTTGCGGCGCATTGCGGGTTTGACGCTGCCCTGCATG
CAGCCGATGCGCGGGAATGCGCGGCGCTGACGGAACGGGAGGGCTGCCCGGCGCTGCTGGTGGTGGATTTCTGGCTGCCG
GACGGCACCGCGGTCGGGTTGCTGCGCGAAGCCGCGGCGCGCCTGCCCGCCTGCAAGCTGCTGGTGATGAGCGCCGACGA
CGATGCGCGCGTTTGCATCAAGGCACGCGAGGCCGGCGCGCACGGCTTTATCCTGAAGAACGAGCCTCCGGAGGTGTTCG
CCACTGCGGTGGCGTCGCTGCGCCAGGGCCGGCGCTGGTTCCAGCAGGCGGGGCCGCCGTCGGCGCGGCGCGAGTTGCCG
CTGGAGCCCAGCGAACTGGGCCTGACGGCGCGCCAGGCCGAGGTGCTTGGCATGATGCTGCGCGGCCTGCCGAACAAGCG
CATCGCCATGACCCTGTCGGTGTCGGAGCAGACCGTCAAGGAGCATGTCACCGCGATCCTCGGCAAGCTCGGCGTGCGCA
ACCGGATCGAGGCTATCGCCCTGCTGCACGGACGCAGGCTGGAGTCATGA

Upstream 100 bases:

>100_bases
GGCGCCGGCGTGCCCATGTGCAGTCAAGGTAATACAATCCACCTGACCAGGCGACGAGACCAATCGACAAGACCATACGC
GCGAACCGGGGTGGGAACTC

Downstream 100 bases:

>100_bases
AGAAGGCCCTCGCCCGGCTGCTGGGCTTGTCGCGCCCGGATGCGGATGCCGGCATCAGCCCGCGCGCGCGTGCGCGGTTG
CTGGACATGACGTTCGGGCG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTRSQGAAENNNDASIDASACRNYAIVVDDHPLMARGIAGYLAAHCGFDAALHAADARECAALTEREGCPALLVVDFWLP
DGTAVGLLREAAARLPACKLLVMSADDDARVCIKAREAGAHGFILKNEPPEVFATAVASLRQGRRWFQQAGPPSARRELP
LEPSELGLTARQAEVLGMMLRGLPNKRIAMTLSVSEQTVKEHVTAILGKLGVRNRIEAIALLHGRRLES

Sequences:

>Translated_229_residues
MTRSQGAAENNNDASIDASACRNYAIVVDDHPLMARGIAGYLAAHCGFDAALHAADARECAALTEREGCPALLVVDFWLP
DGTAVGLLREAAARLPACKLLVMSADDDARVCIKAREAGAHGFILKNEPPEVFATAVASLRQGRRWFQQAGPPSARRELP
LEPSELGLTARQAEVLGMMLRGLPNKRIAMTLSVSEQTVKEHVTAILGKLGVRNRIEAIALLHGRRLES
>Mature_228_residues
TRSQGAAENNNDASIDASACRNYAIVVDDHPLMARGIAGYLAAHCGFDAALHAADARECAALTEREGCPALLVVDFWLPD
GTAVGLLREAAARLPACKLLVMSADDDARVCIKAREAGAHGFILKNEPPEVFATAVASLRQGRRWFQQAGPPSARRELPL
EPSELGLTARQAEVLGMMLRGLPNKRIAMTLSVSEQTVKEHVTAILGKLGVRNRIEAIALLHGRRLES

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=30.5825242718447, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787473, Length=207, Percent_Identity=25.1207729468599, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24582; Mature: 24450

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSQGAAENNNDASIDASACRNYAIVVDDHPLMARGIAGYLAAHCGFDAALHAADAREC
CCCCCCCCCCCCCCCEEHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCHHHH
AALTEREGCPALLVVDFWLPDGTAVGLLREAAARLPACKLLVMSADDDARVCIKAREAGA
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCC
HGFILKNEPPEVFATAVASLRQGRRWFQQAGPPSARRELPLEPSELGLTARQAEVLGMML
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHCCHHHHHHHHHHHH
RGLPNKRIAMTLSVSEQTVKEHVTAILGKLGVRNRIEAIALLHGRRLES
HCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRSQGAAENNNDASIDASACRNYAIVVDDHPLMARGIAGYLAAHCGFDAALHAADAREC
CCCCCCCCCCCCCCEEHHHHCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHCCHHHH
AALTEREGCPALLVVDFWLPDGTAVGLLREAAARLPACKLLVMSADDDARVCIKAREAGA
HHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEEEECCCC
HGFILKNEPPEVFATAVASLRQGRRWFQQAGPPSARRELPLEPSELGLTARQAEVLGMML
CEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHCCHHHHHHHHHHHH
RGLPNKRIAMTLSVSEQTVKEHVTAILGKLGVRNRIEAIALLHGRRLES
HCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]