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The map label for this gene is torS [H]

Identifier: 116694475

GI number: 116694475

Start: 590385

End: 592181

Strand: Direct

Name: torS [H]

Synonym: H16_B0524

Alternate gene names: 116694475

Gene position: 590385-592181 (Clockwise)

Preceding gene: 116694474

Following gene: 116694476

Centisome position: 20.27

GC content: 68.22

Gene sequence:

>1797_bases
ATGAAGAAGGCCCTCGCCCGGCTGCTGGGCTTGTCGCGCCCGGATGCGGATGCCGGCATCAGCCCGCGCGCGCGTGCGCG
GTTGCTGGACATGACGTTCGGGCGCCTGGTGTTCAGCGTCAATGCGATTCCGTTCGTGGGGATGCCTTTCGTCATCTGGC
TGTATGTCCAGAAGCTGGACGGCGGCGCGCTGCTGGCCTGGACACTGGGGTATGGCGCCGCGGCGGTGTGGATGCAATTG
CGCTTCCGGCGCTACAAGCAAGAGCGGGAAGACGATGACGCCCTGGTCCGGCGCTGGCTGCCGTTTGTGCAGCGCGTGGC
GCTGGTGCACGGCTTCTGCCTGTCGCTGGCCGCGGTCCTGACGGCCAGCCTGGGGGGCTTTGACTTCAAGCTGCTGCTGT
ATATCAGCATCGCCGCCATCGTGGCGGCCAATGCCACGCACCAGACGCCGATCCTCGGTGTATTCCAGCGCTTCTTCGTT
GCCTGCTGGACTTTGCAGATCGTCAACACCCCGCGCAGCTTCCCTGAGCACTGGCCGTTCGTGCTGCCGCTGGCGCTGCT
GTATGCGCTGGCCATCTACCGGCACGCGCTGATCGCCAACCAGTTCTTCCGGCAGCAGGTACGGATGGAGGATGACGGCA
TCCGCCTGGCCGAGCGCTACCGGCTGGCCAAGGAAGAGGCCGAGAAAGCCCTGCAGGCCAAGAACCTGTTTCTCACCACC
GCCAGCCACGACCTGCGCCAGCCCGTGCATGCCATGGGCTTCCTGATCGAAGCCATTGCGCGGCGCAACCGCGACCCGGC
CCTGATCCCGCCGCTGGACGACCTGCGGCGCAGCGTGCGCTCGGTGCACCTGATGTTCAACTCACTGCTCGATCTGTCCC
GGATCGAAGGCGGCATTGCCAGCCCGCGCAATACCGCCGTGGCATTTGCGCCCTTGGTCGAAGAGGTGGCGTCGCTGTTC
CGGGAAGAGGCGCGCAGCCGCGGCCTGGACCTGCGCGTGCGCCTGCCCGCAGGCGCCGCCGCGGTGCTGGCCAATCCCGC
ACTGCTGCGCCAGTCTCTGGTCAACCTGGTGCACAACGCGCTGCGCTATACCAAGCGCGGCGGGGTGCTGGTGTCCGCGC
GGCGGCGCGGCAGCCACTGGCTGCTGGAGGTCTGGGACACCGGCGTGGGAATCGCGATCGAAGAGAAGGGGCGGGTCTAC
TCGCCGTTCTATCGCAACGAACATGCGTGGCGCATCGACAGCGCGGGCCATGGGCTGGGCCTTGCCGTGGTGGCGCGCTG
CGCCACCCTGATGGGCGCCACCTACGGCCTGGACTCGGTGGAGCGCCGCGGCTCCAGGTTCTGGCTGCGCTTTCCCGAAG
CGAAGCCGCTGGCGCCGGCGGCGATCGAGCCGGTCTACGAACCCGAAGGCCTGTCGGCGTCCACCCTGCTGCAGGGCGTC
TGCCTGGTCGTCGAGGACGACCCGCTGGTGACCGCCGCGTGGACCAGCCTGATGGAGGCCTGGGGCGTGCAGGCGGCGTG
CGCGGCGTCGGGGCAGGAAGCCCTGGCACTGGTCGATGCCGGCCTGCAGCCCCAGGCGATCCTGTGCGACCAGCGCCTGC
GCTCCGGCGAGAGCGGCTTCGAGGTGCTCAAGGCGCTGTTCGAACGCTGCCCGGACGCAAGCGGCGCCATGGTCAGCGGC
GAGTTCGATTCCGAGGCGCTCCAGCAGGCCGAGCGTGAAGGCTATCTGGTCCTGCACAAGCCACTGGAGCCGTCGCAGCT
GCATGCCTTGTTGTTCCAATGGCTTTGTGCTGCCTGA

Upstream 100 bases:

>100_bases
AGCAGACCGTCAAGGAGCATGTCACCGCGATCCTCGGCAAGCTCGGCGTGCGCAACCGGATCGAGGCTATCGCCCTGCTG
CACGGACGCAGGCTGGAGTC

Downstream 100 bases:

>100_bases
CAGCATAGATCGGTGGTTCTGCTTGCGGCGGTGGCCCCACTCAGGCATCTCCGGGGCGAAAGAAGTGTCCGGATCGACTT
TATTCAGATCACCTGAAGAA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MKKALARLLGLSRPDADAGISPRARARLLDMTFGRLVFSVNAIPFVGMPFVIWLYVQKLDGGALLAWTLGYGAAAVWMQL
RFRRYKQEREDDDALVRRWLPFVQRVALVHGFCLSLAAVLTASLGGFDFKLLLYISIAAIVAANATHQTPILGVFQRFFV
ACWTLQIVNTPRSFPEHWPFVLPLALLYALAIYRHALIANQFFRQQVRMEDDGIRLAERYRLAKEEAEKALQAKNLFLTT
ASHDLRQPVHAMGFLIEAIARRNRDPALIPPLDDLRRSVRSVHLMFNSLLDLSRIEGGIASPRNTAVAFAPLVEEVASLF
REEARSRGLDLRVRLPAGAAAVLANPALLRQSLVNLVHNALRYTKRGGVLVSARRRGSHWLLEVWDTGVGIAIEEKGRVY
SPFYRNEHAWRIDSAGHGLGLAVVARCATLMGATYGLDSVERRGSRFWLRFPEAKPLAPAAIEPVYEPEGLSASTLLQGV
CLVVEDDPLVTAAWTSLMEAWGVQAACAASGQEALALVDAGLQPQAILCDQRLRSGESGFEVLKALFERCPDASGAMVSG
EFDSEALQQAEREGYLVLHKPLEPSQLHALLFQWLCAA

Sequences:

>Translated_598_residues
MKKALARLLGLSRPDADAGISPRARARLLDMTFGRLVFSVNAIPFVGMPFVIWLYVQKLDGGALLAWTLGYGAAAVWMQL
RFRRYKQEREDDDALVRRWLPFVQRVALVHGFCLSLAAVLTASLGGFDFKLLLYISIAAIVAANATHQTPILGVFQRFFV
ACWTLQIVNTPRSFPEHWPFVLPLALLYALAIYRHALIANQFFRQQVRMEDDGIRLAERYRLAKEEAEKALQAKNLFLTT
ASHDLRQPVHAMGFLIEAIARRNRDPALIPPLDDLRRSVRSVHLMFNSLLDLSRIEGGIASPRNTAVAFAPLVEEVASLF
REEARSRGLDLRVRLPAGAAAVLANPALLRQSLVNLVHNALRYTKRGGVLVSARRRGSHWLLEVWDTGVGIAIEEKGRVY
SPFYRNEHAWRIDSAGHGLGLAVVARCATLMGATYGLDSVERRGSRFWLRFPEAKPLAPAAIEPVYEPEGLSASTLLQGV
CLVVEDDPLVTAAWTSLMEAWGVQAACAASGQEALALVDAGLQPQAILCDQRLRSGESGFEVLKALFERCPDASGAMVSG
EFDSEALQQAEREGYLVLHKPLEPSQLHALLFQWLCAA
>Mature_598_residues
MKKALARLLGLSRPDADAGISPRARARLLDMTFGRLVFSVNAIPFVGMPFVIWLYVQKLDGGALLAWTLGYGAAAVWMQL
RFRRYKQEREDDDALVRRWLPFVQRVALVHGFCLSLAAVLTASLGGFDFKLLLYISIAAIVAANATHQTPILGVFQRFFV
ACWTLQIVNTPRSFPEHWPFVLPLALLYALAIYRHALIANQFFRQQVRMEDDGIRLAERYRLAKEEAEKALQAKNLFLTT
ASHDLRQPVHAMGFLIEAIARRNRDPALIPPLDDLRRSVRSVHLMFNSLLDLSRIEGGIASPRNTAVAFAPLVEEVASLF
REEARSRGLDLRVRLPAGAAAVLANPALLRQSLVNLVHNALRYTKRGGVLVSARRRGSHWLLEVWDTGVGIAIEEKGRVY
SPFYRNEHAWRIDSAGHGLGLAVVARCATLMGATYGLDSVERRGSRFWLRFPEAKPLAPAAIEPVYEPEGLSASTLLQGV
CLVVEDDPLVTAAWTSLMEAWGVQAACAASGQEALALVDAGLQPQAILCDQRLRSGESGFEVLKALFERCPDASGAMVSG
EFDSEALQQAEREGYLVLHKPLEPSQLHALLFQWLCAA

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=306, Percent_Identity=31.0457516339869, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI48994928, Length=351, Percent_Identity=26.7806267806268, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=25.8474576271186, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.2295081967213, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=30.7392996108949, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=29.5154185022026, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1790346, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=346, Percent_Identity=24.8554913294798, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=26.5486725663717, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790436, Length=148, Percent_Identity=31.7567567567568, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=27.6018099547511, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=239, Percent_Identity=26.7782426778243, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=30, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=26.5560165975104, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786912, Length=285, Percent_Identity=24.2105263157895, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66202; Mature: 66202

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALARLLGLSRPDADAGISPRARARLLDMTFGRLVFSVNAIPFVGMPFVIWLYVQKLD
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
GGALLAWTLGYGAAAVWMQLRFRRYKQEREDDDALVRRWLPFVQRVALVHGFCLSLAAVL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TASLGGFDFKLLLYISIAAIVAANATHQTPILGVFQRFFVACWTLQIVNTPRSFPEHWPF
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCH
VLPLALLYALAIYRHALIANQFFRQQVRMEDDGIRLAERYRLAKEEAEKALQAKNLFLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
ASHDLRQPVHAMGFLIEAIARRNRDPALIPPLDDLRRSVRSVHLMFNSLLDLSRIEGGIA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SPRNTAVAFAPLVEEVASLFREEARSRGLDLRVRLPAGAAAVLANPALLRQSLVNLVHNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCHHHHHHHHHHHHHHH
LRYTKRGGVLVSARRRGSHWLLEVWDTGVGIAIEEKGRVYSPFYRNEHAWRIDSAGHGLG
HHHHHCCCEEEEECCCCCCEEEEEECCCCCEEECCCCCEECCHHCCCCCEEECCCCCCHH
LAVVARCATLMGATYGLDSVERRGSRFWLRFPEAKPLAPAAIEPVYEPEGLSASTLLQGV
HHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHCCE
CLVVEDDPLVTAAWTSLMEAWGVQAACAASGQEALALVDAGLQPQAILCDQRLRSGESGF
EEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHH
EVLKALFERCPDASGAMVSGEFDSEALQQAEREGYLVLHKPLEPSQLHALLFQWLCAA
HHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKALARLLGLSRPDADAGISPRARARLLDMTFGRLVFSVNAIPFVGMPFVIWLYVQKLD
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
GGALLAWTLGYGAAAVWMQLRFRRYKQEREDDDALVRRWLPFVQRVALVHGFCLSLAAVL
CCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TASLGGFDFKLLLYISIAAIVAANATHQTPILGVFQRFFVACWTLQIVNTPRSFPEHWPF
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCH
VLPLALLYALAIYRHALIANQFFRQQVRMEDDGIRLAERYRLAKEEAEKALQAKNLFLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
ASHDLRQPVHAMGFLIEAIARRNRDPALIPPLDDLRRSVRSVHLMFNSLLDLSRIEGGIA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SPRNTAVAFAPLVEEVASLFREEARSRGLDLRVRLPAGAAAVLANPALLRQSLVNLVHNA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCHHHHHHHHHHHHHHH
LRYTKRGGVLVSARRRGSHWLLEVWDTGVGIAIEEKGRVYSPFYRNEHAWRIDSAGHGLG
HHHHHCCCEEEEECCCCCCEEEEEECCCCCEEECCCCCEECCHHCCCCCEEECCCCCCHH
LAVVARCATLMGATYGLDSVERRGSRFWLRFPEAKPLAPAAIEPVYEPEGLSASTLLQGV
HHHHHHHHHHHHHHCCCHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHCCE
CLVVEDDPLVTAAWTSLMEAWGVQAACAASGQEALALVDAGLQPQAILCDQRLRSGESGF
EEEEECCCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHH
EVLKALFERCPDASGAMVSGEFDSEALQQAEREGYLVLHKPLEPSQLHALLFQWLCAA
HHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]