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The map label for this gene is fadD [C]

Identifier: 116694362

GI number: 116694362

Start: 466322

End: 467026

Strand: Direct

Name: fadD [C]

Synonym: H16_B0409

Alternate gene names: 116694362

Gene position: 466322-467026 (Clockwise)

Preceding gene: 116694356

Following gene: 116694363

Centisome position: 16.01

GC content: 68.79

Gene sequence:

>705_bases
ATGCGCCACCCGCGTCGGGGAGTGCCTGGCGCCATGGCAGCGGCAATCATGCTTCCAGTACTGCCTTCCTGTTACCGCAT
GCCTACGACCAACCCGCATCTTCATTACGTTCCAGCCGGCGTCACGCTTCCCGTGGCGGCGCATGAAGGTGATCCCTTTC
GAAGCCTGAAGGTCATGGCCGAGGCGAATCCGGACGCCGTCGTGGCCACCGACGAGGCCGGCGGACCGCTGACCTGCGCG
CAGTTGCTGAATGCGAGCCTCATGCTGGCGGGATACATGCAGCAGCGCCTGGATGTCCGCGGCGGCGAGCGTGTGTTGCT
GATGCTGCCGGCATATCCCCCGCTGGCAATTGGCTGGTATGCCGCGCTGCGCTGCGATGCTGGCGTGGTCTCGCTGGACC
CTTGCAGCTCCGCTGGGGAAGTGGCGGTATGCCTGAGCGAGTCCGGGGCACGCGTGGCCATTGTCCTGGCGGACGCGCTG
GCCAGCGTGAATCCCATGCTGGAGAACGGACGGCTGCGCGCCTGCATTGCCGCGGCGCCGCCCGCTTCAGACTGGCGCCG
CTCGGGCGGCGCGGGACAGCATCCACGGGTGCATGCATTCGGCGATGCCCTGGCGGCGGGCATCGAGGCGATGCCGGCGC
GGGGCTCGGGCAATGCGCCCGCCTCCCCGCGTGGCGCCCGTACGCCGCACAACTTCCTCCGCTAA

Upstream 100 bases:

>100_bases
CGACGCCTTAAGTCCGCCTTGCAGTGAAACAGCCCCGCGCTCCAGGTGACAGAAACGGGCCCATTCAACTGCCCGTCCGC
CGCAGGCCATATGCGCCGCG

Downstream 100 bases:

>100_bases
CGACACTGCGCCGCAGTCGCCCCTGTTTCTGTCGATGCGCCGCGGCGGATTGCCCGGTCCGGCGCATCGAGTCTCCACCC
CCTGCGGTCTGCTCGGGCCC

Product: hypothetical protein

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA Synthetase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRHPRRGVPGAMAAAIMLPVLPSCYRMPTTNPHLHYVPAGVTLPVAAHEGDPFRSLKVMAEANPDAVVATDEAGGPLTCA
QLLNASLMLAGYMQQRLDVRGGERVLLMLPAYPPLAIGWYAALRCDAGVVSLDPCSSAGEVAVCLSESGARVAIVLADAL
ASVNPMLENGRLRACIAAAPPASDWRRSGGAGQHPRVHAFGDALAAGIEAMPARGSGNAPASPRGARTPHNFLR

Sequences:

>Translated_234_residues
MRHPRRGVPGAMAAAIMLPVLPSCYRMPTTNPHLHYVPAGVTLPVAAHEGDPFRSLKVMAEANPDAVVATDEAGGPLTCA
QLLNASLMLAGYMQQRLDVRGGERVLLMLPAYPPLAIGWYAALRCDAGVVSLDPCSSAGEVAVCLSESGARVAIVLADAL
ASVNPMLENGRLRACIAAAPPASDWRRSGGAGQHPRVHAFGDALAAGIEAMPARGSGNAPASPRGARTPHNFLR
>Mature_234_residues
MRHPRRGVPGAMAAAIMLPVLPSCYRMPTTNPHLHYVPAGVTLPVAAHEGDPFRSLKVMAEANPDAVVATDEAGGPLTCA
QLLNASLMLAGYMQQRLDVRGGERVLLMLPAYPPLAIGWYAALRCDAGVVSLDPCSSAGEVAVCLSESGARVAIVLADAL
ASVNPMLENGRLRACIAAAPPASDWRRSGGAGQHPRVHAFGDALAAGIEAMPARGSGNAPASPRGARTPHNFLR

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 24293; Mature: 24293

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHPRRGVPGAMAAAIMLPVLPSCYRMPTTNPHLHYVPAGVTLPVAAHEGDPFRSLKVMA
CCCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEEE
EANPDAVVATDEAGGPLTCAQLLNASLMLAGYMQQRLDVRGGERVLLMLPAYPPLAIGWY
ECCCCEEEEECCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
AALRCDAGVVSLDPCSSAGEVAVCLSESGARVAIVLADALASVNPMLENGRLRACIAAAP
HHHHCCCCEEEECCCCCCCCEEEEEECCCCEEEEEEEHHHHHCCHHHHCCCEEEEEEECC
PASDWRRSGGAGQHPRVHAFGDALAAGIEAMPARGSGNAPASPRGARTPHNFLR
CHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MRHPRRGVPGAMAAAIMLPVLPSCYRMPTTNPHLHYVPAGVTLPVAAHEGDPFRSLKVMA
CCCCCCCCCHHHHHHHHHHHCHHHHCCCCCCCCEEEECCCEEEEEEECCCCCCCEEEEEE
EANPDAVVATDEAGGPLTCAQLLNASLMLAGYMQQRLDVRGGERVLLMLPAYPPLAIGWY
ECCCCEEEEECCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
AALRCDAGVVSLDPCSSAGEVAVCLSESGARVAIVLADALASVNPMLENGRLRACIAAAP
HHHHCCCCEEEECCCCCCCCEEEEEECCCCEEEEEEEHHHHHCCHHHHCCCEEEEEEECC
PASDWRRSGGAGQHPRVHAFGDALAAGIEAMPARGSGNAPASPRGARTPHNFLR
CHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0024 {myristate}} 0.0021 {myristate}} 0.0012 {myristate}} 0.0002 {myristate}} 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0112 {hexanoate}} 0.0083 {decanoate}} 0.0063 {decanoate}} 0.0043 {dec

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA