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The map label for this gene is gbpR [H]

Identifier: 116694279

GI number: 116694279

Start: 364886

End: 365824

Strand: Direct

Name: gbpR [H]

Synonym: H16_B0325

Alternate gene names: 116694279

Gene position: 364886-365824 (Clockwise)

Preceding gene: 116694274

Following gene: 116694284

Centisome position: 12.53

GC content: 65.71

Gene sequence:

>939_bases
ATGGCCAGACAGACTGCTTCCGCCCCTTCCGCCGTGCTCGCCAAGCTGCGCTTCCGGCACCTGCAGCTGTTGGATGTGCT
GGGACGCAGCCGCAACCTGCGCATCGCGGCCGAGCAATTGCATATCACCCAGCCGGCTGCCACGAAGATACTGAGCGATA
TTGAAGACACCCTGCAGGCCAGGCTGTTCGATCGCTTGCCAAGGGATATGCGCCCGACCGAATTGGGCGAGTTCGCGCTG
CGCTACGCGTCGACGGCGCTGGCCGAGCTCGGCAAGTTTGTGAGCGAGCTGGAAGCGCTACGGGCCGGCGGGCACGGCCA
CCTCACCGTTGGCGCGATTTCGGCGTCGGCCGCGCAGGTGGTGACCACGGCGATCCGCGAGATCCTGCAGCAGCGCCCGC
GGCTGGTCGTCAAGCTGATCGAGCAGAGCAGTGACCAGCTCGCCGTCTGGCTGGAGGACCGGAAGCTGGATATCATGGTC
GGGCGTCTGACCGAGCCACGGCACCAGGCGATCTTCGATTTCGAGGCACTGTCGCCAGAGCCGGTATGGGTCGTCTGCCG
GCCGGGACATCCCCTGCTGGACAGGCCCACGCTGGAAATTGCCGACATCGGCGCATGGCCGTGGATCCTTTACCCGCAGC
TCACCGCCATCCGGCAACTGTTCGATGAAACCATTGCGGCGGCAGGCATCCAGGGCCTGGTCGGCATGGTGGAAACACCG
TCAATCTTTTCCACCCTGGAACTGCTGCAGGCGACGGATATGCTTTCGCTGCAGCCGCGCGCCGTGGTCGAGCGCTTCGT
CGCGGAAGGCATGCTGGCGCACGTGCCGGTGCCGATCCGGCGCGCCATGTCGAGCTACGGCATTGTCACCCGCAAGAATG
AGCTGCCGTCGGAGGCCATGCTGCAGTTCATGGCGGCACTACGGGCGGCGGCCCGGTGA

Upstream 100 bases:

>100_bases
GTCGGGTGGAACTCTACGTGGCAGTCCCATAAACATCCAATCGATTATTGGGTAGAATCGATTCCGTTTAGTTATTGATT
CAGCCGGGTTTACCCCCTTC

Downstream 100 bases:

>100_bases
GACGGCACGGGGATCGGAGATAGCAGGCGGGTCGGATGCGCTGGCCCGGTGTAGACGTGAATATTGCTCCCTGGTATTCG
AAATGTCCGTGGCCCTCGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MARQTASAPSAVLAKLRFRHLQLLDVLGRSRNLRIAAEQLHITQPAATKILSDIEDTLQARLFDRLPRDMRPTELGEFAL
RYASTALAELGKFVSELEALRAGGHGHLTVGAISASAAQVVTTAIREILQQRPRLVVKLIEQSSDQLAVWLEDRKLDIMV
GRLTEPRHQAIFDFEALSPEPVWVVCRPGHPLLDRPTLEIADIGAWPWILYPQLTAIRQLFDETIAAAGIQGLVGMVETP
SIFSTLELLQATDMLSLQPRAVVERFVAEGMLAHVPVPIRRAMSSYGIVTRKNELPSEAMLQFMAALRAAAR

Sequences:

>Translated_312_residues
MARQTASAPSAVLAKLRFRHLQLLDVLGRSRNLRIAAEQLHITQPAATKILSDIEDTLQARLFDRLPRDMRPTELGEFAL
RYASTALAELGKFVSELEALRAGGHGHLTVGAISASAAQVVTTAIREILQQRPRLVVKLIEQSSDQLAVWLEDRKLDIMV
GRLTEPRHQAIFDFEALSPEPVWVVCRPGHPLLDRPTLEIADIGAWPWILYPQLTAIRQLFDETIAAAGIQGLVGMVETP
SIFSTLELLQATDMLSLQPRAVVERFVAEGMLAHVPVPIRRAMSSYGIVTRKNELPSEAMLQFMAALRAAAR
>Mature_311_residues
ARQTASAPSAVLAKLRFRHLQLLDVLGRSRNLRIAAEQLHITQPAATKILSDIEDTLQARLFDRLPRDMRPTELGEFALR
YASTALAELGKFVSELEALRAGGHGHLTVGAISASAAQVVTTAIREILQQRPRLVVKLIEQSSDQLAVWLEDRKLDIMVG
RLTEPRHQAIFDFEALSPEPVWVVCRPGHPLLDRPTLEIADIGAWPWILYPQLTAIRQLFDETIAAAGIQGLVGMVETPS
IFSTLELLQATDMLSLQPRAVVERFVAEGMLAHVPVPIRRAMSSYGIVTRKNELPSEAMLQFMAALRAAAR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=27.027027027027, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI157672245, Length=244, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=270, Percent_Identity=23.7037037037037, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=24.0418118466899, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789204, Length=304, Percent_Identity=24.3421052631579, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790262, Length=261, Percent_Identity=23.7547892720307, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34540; Mature: 34409

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQTASAPSAVLAKLRFRHLQLLDVLGRSRNLRIAAEQLHITQPAATKILSDIEDTLQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHH
RLFDRLPRDMRPTELGEFALRYASTALAELGKFVSELEALRAGGHGHLTVGAISASAAQV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
VTTAIREILQQRPRLVVKLIEQSSDQLAVWLEDRKLDIMVGRLTEPRHQAIFDFEALSPE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCHHHHHEEHHCCCCC
PVWVVCRPGHPLLDRPTLEIADIGAWPWILYPQLTAIRQLFDETIAAAGIQGLVGMVETP
CEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIFSTLELLQATDMLSLQPRAVVERFVAEGMLAHVPVPIRRAMSSYGIVTRKNELPSEAM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCEEECCCCCHHHH
LQFMAALRAAAR
HHHHHHHHHHCC
>Mature Secondary Structure 
ARQTASAPSAVLAKLRFRHLQLLDVLGRSRNLRIAAEQLHITQPAATKILSDIEDTLQA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHH
RLFDRLPRDMRPTELGEFALRYASTALAELGKFVSELEALRAGGHGHLTVGAISASAAQV
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
VTTAIREILQQRPRLVVKLIEQSSDQLAVWLEDRKLDIMVGRLTEPRHQAIFDFEALSPE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCCHHHHHEEHHCCCCC
PVWVVCRPGHPLLDRPTLEIADIGAWPWILYPQLTAIRQLFDETIAAAGIQGLVGMVETP
CEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SIFSTLELLQATDMLSLQPRAVVERFVAEGMLAHVPVPIRRAMSSYGIVTRKNELPSEAM
HHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCEEECCCCCHHHH
LQFMAALRAAAR
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]