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The map label for this gene is pcaI [H]

Identifier: 116694153

GI number: 116694153

Start: 224507

End: 225169

Strand: Direct

Name: pcaI [H]

Synonym: H16_B0198

Alternate gene names: 116694153

Gene position: 224507-225169 (Clockwise)

Preceding gene: 116694151

Following gene: 116694154

Centisome position: 7.71

GC content: 66.21

Gene sequence:

>663_bases
GTGATCAACAAGCTATACGACTCGGTGGAAGCGGCGGTGGCCGGCATCCACGACGGCGCCACCATCCTGATTGGCGGCTT
CGGCCTCGCAGGCATGCCCGCGGAACTGATCGACGCGCTGATCGAGCAAGGCGCGCGCGACCTGACCATCGTCAACAACA
ACGCCGGCAACGGCGACACCGGGCTGGCCGCGCTGCTCAAGACCAAGCGCGTGCGCAAGATCATCTGCTCGTTCCCGCGC
CAGGCGGATTCCTACGTCTTCGATTCGCTCTACCACGCGGGCGAGATCGAGCTGGAACTGGTGCCCCAGGGCAACCTGGC
CGAGCGCATCCGCGCCGCCGGTGCCGGCATCGGCGGCTTCTTCACGCGCACCGCCTACGGCACGCCGCTGGCCGAGGGCA
AGGAAACGCGCATCATCGACGGCCAGGGCTATGTGTTCGAGACCCCGATCCACGCCGACTTCGCGCTGATCAAGGCCGAC
ACCGCCGACCGCTGGGGCAACCTTACCTATCGCAAGACTGCGCGCAATTTCGGCCCGATCATGGCGATGGCCGCCAAATG
CGCCATCGTGCAAGTCAGCCACGTGGTGGAGCTGGGCGAGATGGACCCCGAACACATCGTGACGCCGGGCCTCTTCGTCA
AGCGCGTCGTCAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
ACGAAACTCCTTCCGGCAGGATTACCGGAGACAGCCTTTCATGCGCCGCGTCTTGCGGCCCGCTCCGGTAGCCTGGCGGA
TCTTCCGACCTGGAACGCAA

Downstream 100 bases:

>100_bases
GCGACAGGTAACAGGAGAATCCAGATGCAACGCCTGACCCGCGATCAGATGGCCGCCCGCGTGGCCAAAGACATTCCCGA
CGGTGCCGTGGTCAACCTCG

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MINKLYDSVEAAVAGIHDGATILIGGFGLAGMPAELIDALIEQGARDLTIVNNNAGNGDTGLAALLKTKRVRKIICSFPR
QADSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGKETRIIDGQGYVFETPIHADFALIKAD
TADRWGNLTYRKTARNFGPIMAMAAKCAIVQVSHVVELGEMDPEHIVTPGLFVKRVVKVA

Sequences:

>Translated_220_residues
MINKLYDSVEAAVAGIHDGATILIGGFGLAGMPAELIDALIEQGARDLTIVNNNAGNGDTGLAALLKTKRVRKIICSFPR
QADSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGKETRIIDGQGYVFETPIHADFALIKAD
TADRWGNLTYRKTARNFGPIMAMAAKCAIVQVSHVVELGEMDPEHIVTPGLFVKRVVKVA
>Mature_220_residues
MINKLYDSVEAAVAGIHDGATILIGGFGLAGMPAELIDALIEQGARDLTIVNNNAGNGDTGLAALLKTKRVRKIICSFPR
QADSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGKETRIIDGQGYVFETPIHADFALIKAD
TADRWGNLTYRKTARNFGPIMAMAAKCAIVQVSHVVELGEMDPEHIVTPGLFVKRVVKVA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=233, Percent_Identity=43.3476394849785, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI11545841, Length=233, Percent_Identity=43.7768240343348, Blast_Score=176, Evalue=1e-44,
Organism=Escherichia coli, GI1788551, Length=221, Percent_Identity=42.9864253393665, Blast_Score=184, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.4599156118143, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21358325, Length=233, Percent_Identity=42.0600858369099, Blast_Score=183, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24655794, Length=233, Percent_Identity=42.0600858369099, Blast_Score=183, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 23555; Mature: 23555

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKLYDSVEAAVAGIHDGATILIGGFGLAGMPAELIDALIEQGARDLTIVNNNAGNGDT
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKTKRVRKIICSFPRQADSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCHH
FTRTAYGTPLAEGKETRIIDGQGYVFETPIHADFALIKADTADRWGNLTYRKTARNFGPI
HHHHCCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHH
MAMAAKCAIVQVSHVVELGEMDPEHIVTPGLFVKRVVKVA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MINKLYDSVEAAVAGIHDGATILIGGFGLAGMPAELIDALIEQGARDLTIVNNNAGNGDT
CCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKTKRVRKIICSFPRQADSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCHH
FTRTAYGTPLAEGKETRIIDGQGYVFETPIHADFALIKADTADRWGNLTYRKTARNFGPI
HHHHCCCCCCCCCCCEEEECCCCEEEECCCCCCEEEEEECCCHHHCCCCHHHHHHHHHHH
MAMAAKCAIVQVSHVVELGEMDPEHIVTPGLFVKRVVKVA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]