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The map label for this gene is ltrA [H]

Identifier: 113478104

GI number: 113478104

Start: 7261363

End: 7262676

Strand: Reverse

Name: ltrA [H]

Synonym: Tery_4731

Alternate gene names: 113478104

Gene position: 7262676-7261363 (Counterclockwise)

Preceding gene: 113478105

Following gene: 113478103

Centisome position: 93.71

GC content: 41.86

Gene sequence:

>1314_bases
ATGAAACTGATGCTACGCAGTTACTCCAACCTACTACTGTCAGTGCGAAGGGTGACTCAAGAAAACCAAGGGATACGAAG
GATGGGGAGAGACGCTCAGACGGCAAAGACTTCTGTAGAAAAAGTCAAACTTGTCAAAGAAATGCTGACATATAGGCTGT
GGCAAGCCAAACCAGCTAAAAGGGTATACATCCCCAAGGCAAACCGTCAACAAGGTCCACTAGGCATCCCCACAGTCAAA
AACCGAGTTGCTCAGGCAGTTGTTAAGAATGGGTTAGAACCAATTTGGGACGCAGAATTCGAGACAAATTCCTACGGATT
CCACCCAGGTAGAAGTTGCCATGATCCTCTTGAACAATTCTGGATTAGACTCCAAAAAGGAAAGGATACATGGATACTAG
ATGTCGATATTAAACAAGATTTTGACAATATTACCCATGAATACATCCTCAAAGCTATCGGAGAAATCCCTGGTAGAGAG
TTAATCAAGCAATGGCTAAAAGCAGGGTATTTAGAAGCCGAAGTTTTCCACAAGACAGAGGGGGGGACTTCTTCAAGAGG
CATAATTAGCCCCTTACTTGCCAACATAGCCTTTGATGGGATGGAAAGATTGTTAGCTAGGTACAAAACAGTGAAAACCT
ATCAATGTACAAGGCCGACAACGGATGAGGAATACACCAAGAAAAAGAAGTTAGATAAATACGGATTTATCCGATACGCT
GATGACTTCATAATCACCGCTCGAAGTGAGGAAGACATCAAAGCGATAATCCCCACTATTGAAAAATGGCTATCAGAAAG
AGGATTAGAACTTAATAAGGACAAAACCAACTTAGTTCATATTGAACAAGGATTCAACTTTTTAGGGTTCAATGTCCGCC
AGTTCAACGGTAGCTGCTTCATAGTTCCACAAAAAGAGAAAGTTAAGGAATTTCTCACACTAATTCGGGGGTGGCTCAAA
GCACACCCGACCAGTACACAAGAAGCAGTAATTGCAAACCTTAATTCAATTATTAGAGGATGGGGGAACTACTACAGACA
TGGTGTAAGTCAACGAATATTTTCCTATGTTGACCACGAAATTTGGAAATCACTCTGGCAATGGTCATTAAGAAGACACT
CGAAGCGAGTGGGGAAACAAAAAGGAAAAGGTAAGGAATGGGTGCGAAAGAAATACTTCAAAACCGTCAACGGAAACAAG
TGGACTTTCGCAACAAACATAAGCAATAGGTATGGCAAGAAGGAAACAATAGCCATCTGCCGACTAGGAAAAGTTCCCAT
TCAACGTCATGTAAAAATTAAAGGCACGGCATAG

Upstream 100 bases:

>100_bases
GGACATTAATTGGAAGACCATTAAAAAGTGTGTTAGGAACCTAAGACGGAGAATTTATCGTGCTAAACAGAACAGTCAGT
GGAATAAGGTTCGCAGCCTA

Downstream 100 bases:

>100_bases
CCGGAGAACCCCTCTTTAACCAAATATTTGAAATAACGTTATACAAAATATGACAAAGCTCATCGGGTCAAGGTTCAAAA
TACTACAAAATTACCTAAGC

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKLMLRSYSNLLLSVRRVTQENQGIRRMGRDAQTAKTSVEKVKLVKEMLTYRLWQAKPAKRVYIPKANRQQGPLGIPTVK
NRVAQAVVKNGLEPIWDAEFETNSYGFHPGRSCHDPLEQFWIRLQKGKDTWILDVDIKQDFDNITHEYILKAIGEIPGRE
LIKQWLKAGYLEAEVFHKTEGGTSSRGIISPLLANIAFDGMERLLARYKTVKTYQCTRPTTDEEYTKKKKLDKYGFIRYA
DDFIITARSEEDIKAIIPTIEKWLSERGLELNKDKTNLVHIEQGFNFLGFNVRQFNGSCFIVPQKEKVKEFLTLIRGWLK
AHPTSTQEAVIANLNSIIRGWGNYYRHGVSQRIFSYVDHEIWKSLWQWSLRRHSKRVGKQKGKGKEWVRKKYFKTVNGNK
WTFATNISNRYGKKETIAICRLGKVPIQRHVKIKGTA

Sequences:

>Translated_437_residues
MKLMLRSYSNLLLSVRRVTQENQGIRRMGRDAQTAKTSVEKVKLVKEMLTYRLWQAKPAKRVYIPKANRQQGPLGIPTVK
NRVAQAVVKNGLEPIWDAEFETNSYGFHPGRSCHDPLEQFWIRLQKGKDTWILDVDIKQDFDNITHEYILKAIGEIPGRE
LIKQWLKAGYLEAEVFHKTEGGTSSRGIISPLLANIAFDGMERLLARYKTVKTYQCTRPTTDEEYTKKKKLDKYGFIRYA
DDFIITARSEEDIKAIIPTIEKWLSERGLELNKDKTNLVHIEQGFNFLGFNVRQFNGSCFIVPQKEKVKEFLTLIRGWLK
AHPTSTQEAVIANLNSIIRGWGNYYRHGVSQRIFSYVDHEIWKSLWQWSLRRHSKRVGKQKGKGKEWVRKKYFKTVNGNK
WTFATNISNRYGKKETIAICRLGKVPIQRHVKIKGTA
>Mature_437_residues
MKLMLRSYSNLLLSVRRVTQENQGIRRMGRDAQTAKTSVEKVKLVKEMLTYRLWQAKPAKRVYIPKANRQQGPLGIPTVK
NRVAQAVVKNGLEPIWDAEFETNSYGFHPGRSCHDPLEQFWIRLQKGKDTWILDVDIKQDFDNITHEYILKAIGEIPGRE
LIKQWLKAGYLEAEVFHKTEGGTSSRGIISPLLANIAFDGMERLLARYKTVKTYQCTRPTTDEEYTKKKKLDKYGFIRYA
DDFIITARSEEDIKAIIPTIEKWLSERGLELNKDKTNLVHIEQGFNFLGFNVRQFNGSCFIVPQKEKVKEFLTLIRGWLK
AHPTSTQEAVIANLNSIIRGWGNYYRHGVSQRIFSYVDHEIWKSLWQWSLRRHSKRVGKQKGKGKEWVRKKYFKTVNGNK
WTFATNISNRYGKKETIAICRLGKVPIQRHVKIKGTA

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226521, Length=290, Percent_Identity=27.5862068965517, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6226520, Length=339, Percent_Identity=26.8436578171091, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 50836; Mature: 50836

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMLRSYSNLLLSVRRVTQENQGIRRMGRDAQTAKTSVEKVKLVKEMLTYRLWQAKPAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RVYIPKANRQQGPLGIPTVKNRVAQAVVKNGLEPIWDAEFETNSYGFHPGRSCHDPLEQF
EEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
WIRLQKGKDTWILDVDIKQDFDNITHEYILKAIGEIPGRELIKQWLKAGYLEAEVFHKTE
HHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHEECCC
GGTSSRGIISPLLANIAFDGMERLLARYKTVKTYQCTRPTTDEEYTKKKKLDKYGFIRYA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHCCEEEE
DDFIITARSEEDIKAIIPTIEKWLSERGLELNKDKTNLVHIEQGFNFLGFNVRQFNGSCF
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEEECCEEE
IVPQKEKVKEFLTLIRGWLKAHPTSTQEAVIANLNSIIRGWGNYYRHGVSQRIFSYVDHE
EEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWKSLWQWSLRRHSKRVGKQKGKGKEWVRKKYFKTVNGNKWTFATNISNRYGKKETIAIC
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHHHHHE
RLGKVPIQRHVKIKGTA
ECCCCCCCCCEEEECCC
>Mature Secondary Structure
MKLMLRSYSNLLLSVRRVTQENQGIRRMGRDAQTAKTSVEKVKLVKEMLTYRLWQAKPAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RVYIPKANRQQGPLGIPTVKNRVAQAVVKNGLEPIWDAEFETNSYGFHPGRSCHDPLEQF
EEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
WIRLQKGKDTWILDVDIKQDFDNITHEYILKAIGEIPGRELIKQWLKAGYLEAEVFHKTE
HHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHEECCC
GGTSSRGIISPLLANIAFDGMERLLARYKTVKTYQCTRPTTDEEYTKKKKLDKYGFIRYA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHCCEEEE
DDFIITARSEEDIKAIIPTIEKWLSERGLELNKDKTNLVHIEQGFNFLGFNVRQFNGSCF
CCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEEECCEEE
IVPQKEKVKEFLTLIRGWLKAHPTSTQEAVIANLNSIIRGWGNYYRHGVSQRIFSYVDHE
EEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWKSLWQWSLRRHSKRVGKQKGKGKEWVRKKYFKTVNGNKWTFATNISNRYGKKETIAIC
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHHHHHE
RLGKVPIQRHVKIKGTA
ECCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]