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The map label for this gene is purN [H]

Identifier: 113478017

GI number: 113478017

Start: 7123026

End: 7123745

Strand: Reverse

Name: purN [H]

Synonym: Tery_4633

Alternate gene names: 113478017

Gene position: 7123745-7123026 (Counterclockwise)

Preceding gene: 113478018

Following gene: 113478016

Centisome position: 91.92

GC content: 32.08

Gene sequence:

>720_bases
ATGACTATAATACTGTATAATTTAAATAATTTACACTATTGTATTTTACACAAAATGAAAACTGAAACTCAACTAATTAA
TTCTAATTCTTGTTTAGTTTCTCCAGCTATTCCTGAAAATGCTTTGCCAAAATTTTCTCCTATAAAATTGGGGATTCTAG
CTTCTGGTAATGGGAGTAATTTTGAGGCTATTGCAGAAGCGATAAGTAATCAAAAATTAAATGCCAAAATTCAGGTAATG
ATTTATAACAATCCTGGAGCTAAGGTTACATCACGAGCAGAAAAGTGGAATGTTCCATCAGTATTGTTAAATCATCGAAA
ATACAAAAACCGAGAAGAATTTGATAGTCAAATTGTCAAAACTTTACAAGAATACAATGTAGAGTGGGTGATTATGGCTG
GTTGGATGCGAATAGTTACTAAAATTTTAATAGATGCTTTTCCTAATCAAATCATCAATATTCATCCTAGTTTGTTGCCT
AGTTTTAAGGGTATAGAAGCAGTTGAACAAGCTTTAAATGCAGGAGTAAAAATAACTGGTTGTACAGTACATTTAGTGGA
TGTAGAAGTCGATAATGGTCCGATTTTAATGCAGGCTGCTGTACCAATTTTGCTTGATGATACACCAGAAACTCTCCACC
AGAAAATTCAAGTGCAAGAACATAAAATTATTGTGGGTGCTATTACTCTTGCTGCATCAAAAAAAATTGGTTTTAAGTAG

Upstream 100 bases:

>100_bases
AATTTAATGCCTTAATTCTTACATAATATTTGACTTTTAATATTTAAAAAATACATATTTTTATTAATGTATAAAAAAAC
CTAGATTATTAGTTGTAAAT

Downstream 100 bases:

>100_bases
TAGTTAAAATTTCAGTATTTAACTTAATAAGAGAAGAATTAATTTGAATATAGAATAAATATTAAAACCCACTTACCCTT
TTTTTCAAGATTTAATTAAA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MTIILYNLNNLHYCILHKMKTETQLINSNSCLVSPAIPENALPKFSPIKLGILASGNGSNFEAIAEAISNQKLNAKIQVM
IYNNPGAKVTSRAEKWNVPSVLLNHRKYKNREEFDSQIVKTLQEYNVEWVIMAGWMRIVTKILIDAFPNQIINIHPSLLP
SFKGIEAVEQALNAGVKITGCTVHLVDVEVDNGPILMQAAVPILLDDTPETLHQKIQVQEHKIIVGAITLAASKKIGFK

Sequences:

>Translated_239_residues
MTIILYNLNNLHYCILHKMKTETQLINSNSCLVSPAIPENALPKFSPIKLGILASGNGSNFEAIAEAISNQKLNAKIQVM
IYNNPGAKVTSRAEKWNVPSVLLNHRKYKNREEFDSQIVKTLQEYNVEWVIMAGWMRIVTKILIDAFPNQIINIHPSLLP
SFKGIEAVEQALNAGVKITGCTVHLVDVEVDNGPILMQAAVPILLDDTPETLHQKIQVQEHKIIVGAITLAASKKIGFK
>Mature_238_residues
TIILYNLNNLHYCILHKMKTETQLINSNSCLVSPAIPENALPKFSPIKLGILASGNGSNFEAIAEAISNQKLNAKIQVMI
YNNPGAKVTSRAEKWNVPSVLLNHRKYKNREEFDSQIVKTLQEYNVEWVIMAGWMRIVTKILIDAFPNQIINIHPSLLPS
FKGIEAVEQALNAGVKITGCTVHLVDVEVDNGPILMQAAVPILLDDTPETLHQKIQVQEHKIIVGAITLAASKKIGFK

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=188, Percent_Identity=42.0212765957447, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI209869995, Length=188, Percent_Identity=42.0212765957447, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI209869993, Length=188, Percent_Identity=42.0212765957447, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1788846, Length=185, Percent_Identity=31.8918918918919, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787483, Length=224, Percent_Identity=28.125, Blast_Score=102, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567511, Length=187, Percent_Identity=38.5026737967914, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320616, Length=199, Percent_Identity=28.643216080402, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582400, Length=175, Percent_Identity=38.8571428571429, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 26525; Mature: 26394

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILYNLNNLHYCILHKMKTETQLINSNSCLVSPAIPENALPKFSPIKLGILASGNGSN
CEEEEEECCCEEEEEEEHHHHHHHEECCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCC
FEAIAEAISNQKLNAKIQVMIYNNPGAKVTSRAEKWNVPSVLLNHRKYKNREEFDSQIVK
HHHHHHHHCCCCCCEEEEEEEECCCCCCEECCHHHCCCHHHHHHHHHCCCHHHHHHHHHH
TLQEYNVEWVIMAGWMRIVTKILIDAFPNQIINIHPSLLPSFKGIEAVEQALNAGVKITG
HHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCHHHHHHHHHCCEEEEE
CTVHLVDVEVDNGPILMQAAVPILLDDTPETLHQKIQVQEHKIIVGAITLAASKKIGFK
EEEEEEEEEECCCCEEEEECCEEEECCCHHHHHHHHHHHCCEEEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TIILYNLNNLHYCILHKMKTETQLINSNSCLVSPAIPENALPKFSPIKLGILASGNGSN
EEEEEECCCEEEEEEEHHHHHHHEECCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCC
FEAIAEAISNQKLNAKIQVMIYNNPGAKVTSRAEKWNVPSVLLNHRKYKNREEFDSQIVK
HHHHHHHHCCCCCCEEEEEEEECCCCCCEECCHHHCCCHHHHHHHHHCCCHHHHHHHHHH
TLQEYNVEWVIMAGWMRIVTKILIDAFPNQIINIHPSLLPSFKGIEAVEQALNAGVKITG
HHHHCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCCHHHHHHHHHCCEEEEE
CTVHLVDVEVDNGPILMQAAVPILLDDTPETLHQKIQVQEHKIIVGAITLAASKKIGFK
EEEEEEEEEECCCCEEEEECCEEEECCCHHHHHHHHHHHCCEEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]