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The map label for this gene is cyaB [H]

Identifier: 113477973

GI number: 113477973

Start: 7051997

End: 7054231

Strand: Reverse

Name: cyaB [H]

Synonym: Tery_4585

Alternate gene names: 113477973

Gene position: 7054231-7051997 (Counterclockwise)

Preceding gene: 113477974

Following gene: 113477972

Centisome position: 91.02

GC content: 36.38

Gene sequence:

>2235_bases
ATGTTATGGAGTAAGTTTCTTTGTTTTTTTAATCAATGGTATGGTGTCTGGATAACTGGACCCAGTATAACAGGATTAAT
AATCCTACTGCGTTTTTTGGGCTTACTACAGTTTTGGGAGTGGAGCGCTTATGATGGATATATGCGTATGCGGCCTTTGG
AAAGTCGAGACAATAGAATTGCTATTGTGGGCATTAATGAAGACGACCTTAGAGCTATTGGGCAACCAATTTTTCCTGAT
GCTGTTTATGCGGACTTGCTGAATAAATTGAAAGCAATGAAGCCAAAAGTTATTGGCTTAGATATTTATCGGGATTTACC
TGTGGAACCTGGTCATCAGAAATTAGTGGAAGTATTCAAGTCTACCCCCAATATAGTTGGAATTAAAAAGGTAGTGGGAG
AAAGACAAGCGGACGTTACAGAAGCAGCACCTGTTTTGGAGGAGAATAAGCGGGCAGGTGCTAATGATTTAAAAGTAGAT
TCAGATCAAAAAATTCGACGGGCTTATTTATTTGTGACCCTTCAAAATAGACAAAATATCTTAAGTTTTGCTTCTCATAT
TGCTTTGCGGTATTTAAAGAGTTTTGATATTAGCCCAGAGCAAATTGAGGGTGACAAATATCAGTTAGGCAAGGCTGTAT
TAGAACCATTTGAAGCTGATGATGGTGGCTATGTACGGGCAGATGCAGGTGGTTTTCTAATTATTTTGAACTACCGTGGT
CCTAGTCGCTCCTTCGAGACTGTTTCCATGATGGATATTTTAAAAGATCGAGTACCTCTTGACTGGGGTCGCGATCGAAT
TATTTTGATTGGAGCGGTGGGTCAAAGTTTTAATGATTTACATTCTACTCCCTACAGTAGTAGCTTAATTAGAAGTTTAG
AACCTATGAGTGGGGTTGAAGTTCATGCTAATCTAATTAGTCAACTGATTAGTTCTGCTATTGATGGTCGTTCCATGATT
AAAATTTGGGGGGATACCTACGAATGGATATGGATTTTATTTTGGTCTGGAGTAGGATCTGCAACAACTTGGAAATGGCG
AACTGGTGTTAGTGTTAGTTATTTTTCTATTTGGAAAGTAATTACGATTTTTGTGGCTGGTGGAGTTTTATTTGCTAGCA
CTTATATTGCTTTTTTGTGGAACTGGTGGTTGCCTGTTGTTCCTGCGTTTTTAGGTATGATTACATCAGCAATTGTGATT
ACAGCTTATATTGCTCGTACTGCTCAGAATATTCGCAAAACTTTCGGTCGTTATTTAACCGATGAAGTAGTGGCTACTTT
ATTAGAAAGTCCGCAAGGGTTAAAGTTAGGAGGCGAGCGCCGTAAAATTACAATTTTAACTTCCGATCTCAGAGGTTTTA
CTGCTACATCAGAACGTTTGCCACCAGAAGAAGTTGTGAAAATTCTTAACTTTTATTTGGGATATATGGCAGATGTAATT
ACTGAGTATCAGGGAACTATTGATGAGTTTATGGGAGATGGAATTTTAGTTTTATTTGGTGCTCCTACTTATAGAGGAGA
CGATCCGACAAGAGCTGTTGCTTGTGCAATTGCTATGCAGTTGGCAATGGAACCTGTAAATAAACAAATGAAAGAGTGGG
GTTTGACACCTTTAGAAATGGGAATTGGGATTAATACAGGAGAAGTTGTTGTTGGTAATATTGGTTCCTGGAAACGGACA
AAATATGGTATTGTTGGCAATCAAGTAAATTTAACTTATCGAATTGAATCTTATACTACTGGGGGGCAAATTTTAATTTC
TGAAACTACTTTAAATGAAGTAGGATCAATAATTAAAATTAATGGTAAAAAAGAGGTTATGCCAAAAGGAGTAAAAAAGC
CAATTACTATTTATGACCTTGGTGGTATTGGTGGTAAATATAATTTATTTTTACCGAAAGAAGAAGAAATTTATTTGCCT
CTAAAAGAAGCAATTTCTTTACATTATGTAGTTTTAGATGGCAAAAATGTTAGTGCTTGTGGTCAGAGTGGAAGTTTGGT
AAAGTTGTCGAAAAAAGAAGCAGAAATTCAGGTAGTAAATTCAGGGGAAAATATTCCCCATGCTTTGATTAATATTAAGA
TTAATTTTTTCTGGGATGGAAAAGAAAGTGAGGATGTTTATGGCAAAGTTTTAGATAAAAAAGCAGAAAATGGTAATTTT
TATATTCATTTTACGGCTAAACCACCTGATGTTTCGGCTAAGTTAGAATCTTTGTATAAATCCCTGCAAACTTAA

Upstream 100 bases:

>100_bases
AACAGGACTGCCCCTAAATTTTTTCAGGGCAGCCTCAGTTTGATTGTGTAGTAAAGTTAGTAAGATTAACCTGTTTTTTT
CTAAAAGGTGCTAATCAAGA

Downstream 100 bases:

>100_bases
TGGTTAATTATTACTATGACTCAGTCTGAATTGATGAGTTTTGAATATCAAAATTTATAACAAGTAAACTTACTCAAAGT
TAGAGAATTAGGCACGCTAA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MLWSKFLCFFNQWYGVWITGPSITGLIILLRFLGLLQFWEWSAYDGYMRMRPLESRDNRIAIVGINEDDLRAIGQPIFPD
AVYADLLNKLKAMKPKVIGLDIYRDLPVEPGHQKLVEVFKSTPNIVGIKKVVGERQADVTEAAPVLEENKRAGANDLKVD
SDQKIRRAYLFVTLQNRQNILSFASHIALRYLKSFDISPEQIEGDKYQLGKAVLEPFEADDGGYVRADAGGFLIILNYRG
PSRSFETVSMMDILKDRVPLDWGRDRIILIGAVGQSFNDLHSTPYSSSLIRSLEPMSGVEVHANLISQLISSAIDGRSMI
KIWGDTYEWIWILFWSGVGSATTWKWRTGVSVSYFSIWKVITIFVAGGVLFASTYIAFLWNWWLPVVPAFLGMITSAIVI
TAYIARTAQNIRKTFGRYLTDEVVATLLESPQGLKLGGERRKITILTSDLRGFTATSERLPPEEVVKILNFYLGYMADVI
TEYQGTIDEFMGDGILVLFGAPTYRGDDPTRAVACAIAMQLAMEPVNKQMKEWGLTPLEMGIGINTGEVVVGNIGSWKRT
KYGIVGNQVNLTYRIESYTTGGQILISETTLNEVGSIIKINGKKEVMPKGVKKPITIYDLGGIGGKYNLFLPKEEEIYLP
LKEAISLHYVVLDGKNVSACGQSGSLVKLSKKEAEIQVVNSGENIPHALINIKINFFWDGKESEDVYGKVLDKKAENGNF
YIHFTAKPPDVSAKLESLYKSLQT

Sequences:

>Translated_744_residues
MLWSKFLCFFNQWYGVWITGPSITGLIILLRFLGLLQFWEWSAYDGYMRMRPLESRDNRIAIVGINEDDLRAIGQPIFPD
AVYADLLNKLKAMKPKVIGLDIYRDLPVEPGHQKLVEVFKSTPNIVGIKKVVGERQADVTEAAPVLEENKRAGANDLKVD
SDQKIRRAYLFVTLQNRQNILSFASHIALRYLKSFDISPEQIEGDKYQLGKAVLEPFEADDGGYVRADAGGFLIILNYRG
PSRSFETVSMMDILKDRVPLDWGRDRIILIGAVGQSFNDLHSTPYSSSLIRSLEPMSGVEVHANLISQLISSAIDGRSMI
KIWGDTYEWIWILFWSGVGSATTWKWRTGVSVSYFSIWKVITIFVAGGVLFASTYIAFLWNWWLPVVPAFLGMITSAIVI
TAYIARTAQNIRKTFGRYLTDEVVATLLESPQGLKLGGERRKITILTSDLRGFTATSERLPPEEVVKILNFYLGYMADVI
TEYQGTIDEFMGDGILVLFGAPTYRGDDPTRAVACAIAMQLAMEPVNKQMKEWGLTPLEMGIGINTGEVVVGNIGSWKRT
KYGIVGNQVNLTYRIESYTTGGQILISETTLNEVGSIIKINGKKEVMPKGVKKPITIYDLGGIGGKYNLFLPKEEEIYLP
LKEAISLHYVVLDGKNVSACGQSGSLVKLSKKEAEIQVVNSGENIPHALINIKINFFWDGKESEDVYGKVLDKKAENGNF
YIHFTAKPPDVSAKLESLYKSLQT
>Mature_744_residues
MLWSKFLCFFNQWYGVWITGPSITGLIILLRFLGLLQFWEWSAYDGYMRMRPLESRDNRIAIVGINEDDLRAIGQPIFPD
AVYADLLNKLKAMKPKVIGLDIYRDLPVEPGHQKLVEVFKSTPNIVGIKKVVGERQADVTEAAPVLEENKRAGANDLKVD
SDQKIRRAYLFVTLQNRQNILSFASHIALRYLKSFDISPEQIEGDKYQLGKAVLEPFEADDGGYVRADAGGFLIILNYRG
PSRSFETVSMMDILKDRVPLDWGRDRIILIGAVGQSFNDLHSTPYSSSLIRSLEPMSGVEVHANLISQLISSAIDGRSMI
KIWGDTYEWIWILFWSGVGSATTWKWRTGVSVSYFSIWKVITIFVAGGVLFASTYIAFLWNWWLPVVPAFLGMITSAIVI
TAYIARTAQNIRKTFGRYLTDEVVATLLESPQGLKLGGERRKITILTSDLRGFTATSERLPPEEVVKILNFYLGYMADVI
TEYQGTIDEFMGDGILVLFGAPTYRGDDPTRAVACAIAMQLAMEPVNKQMKEWGLTPLEMGIGINTGEVVVGNIGSWKRT
KYGIVGNQVNLTYRIESYTTGGQILISETTLNEVGSIIKINGKKEVMPKGVKKPITIYDLGGIGGKYNLFLPKEEEIYLP
LKEAISLHYVVLDGKNVSACGQSGSLVKLSKKEAEIQVVNSGENIPHALINIKINFFWDGKESEDVYGKVLDKKAENGNF
YIHFTAKPPDVSAKLESLYKSLQT

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI148536830, Length=153, Percent_Identity=28.7581699346405, Blast_Score=71, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71989822, Length=181, Percent_Identity=29.8342541436464, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71989805, Length=198, Percent_Identity=29.2929292929293, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585694, Length=154, Percent_Identity=29.8701298701299, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076872, Length=161, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574512, Length=161, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 83199; Mature: 83199

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSKFLCFFNQWYGVWITGPSITGLIILLRFLGLLQFWEWSAYDGYMRMRPLESRDNRI
CCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEE
AIVGINEDDLRAIGQPIFPDAVYADLLNKLKAMKPKVIGLDIYRDLPVEPGHQKLVEVFK
EEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHH
STPNIVGIKKVVGERQADVTEAAPVLEENKRAGANDLKVDSDQKIRRAYLFVTLQNRQNI
CCCCCEEHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEEEEEEECCCHHH
LSFASHIALRYLKSFDISPEQIEGDKYQLGKAVLEPFEADDGGYVRADAGGFLIILNYRG
HHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECC
PSRSFETVSMMDILKDRVPLDWGRDRIILIGAVGQSFNDLHSTPYSSSLIRSLEPMSGVE
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHCCCCCHHHHHHHCCCCCCHH
VHANLISQLISSAIDGRSMIKIWGDTYEWIWILFWSGVGSATTWKWRTGVSVSYFSIWKV
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCEEHHHHHHHH
ITIFVAGGVLFASTYIAFLWNWWLPVVPAFLGMITSAIVITAYIARTAQNIRKTFGRYLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEVVATLLESPQGLKLGGERRKITILTSDLRGFTATSERLPPEEVVKILNFYLGYMADVI
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEYQGTIDEFMGDGILVLFGAPTYRGDDPTRAVACAIAMQLAMEPVNKQMKEWGLTPLEM
HHHHCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GIGINTGEVVVGNIGSWKRTKYGIVGNQVNLTYRIESYTTGGQILISETTLNEVGSIIKI
CCCCCCCCEEEECCCCCCCEEECEECCEEEEEEEEEEECCCCEEEEEECCHHHCCCEEEE
NGKKEVMPKGVKKPITIYDLGGIGGKYNLFLPKEEEIYLPLKEAISLHYVVLDGKNVSAC
CCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEHHHCCEEEEEEEECCCCCCC
GQSGSLVKLSKKEAEIQVVNSGENIPHALINIKINFFWDGKESEDVYGKVLDKKAENGNF
CCCCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCE
YIHFTAKPPDVSAKLESLYKSLQT
EEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLWSKFLCFFNQWYGVWITGPSITGLIILLRFLGLLQFWEWSAYDGYMRMRPLESRDNRI
CCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEE
AIVGINEDDLRAIGQPIFPDAVYADLLNKLKAMKPKVIGLDIYRDLPVEPGHQKLVEVFK
EEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHH
STPNIVGIKKVVGERQADVTEAAPVLEENKRAGANDLKVDSDQKIRRAYLFVTLQNRQNI
CCCCCEEHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHEEEEEEEEEECCCHHH
LSFASHIALRYLKSFDISPEQIEGDKYQLGKAVLEPFEADDGGYVRADAGGFLIILNYRG
HHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECC
PSRSFETVSMMDILKDRVPLDWGRDRIILIGAVGQSFNDLHSTPYSSSLIRSLEPMSGVE
CCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHCCCCCHHHHHHHCCCCCCHH
VHANLISQLISSAIDGRSMIKIWGDTYEWIWILFWSGVGSATTWKWRTGVSVSYFSIWKV
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCEEHHHHHHHH
ITIFVAGGVLFASTYIAFLWNWWLPVVPAFLGMITSAIVITAYIARTAQNIRKTFGRYLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEVVATLLESPQGLKLGGERRKITILTSDLRGFTATSERLPPEEVVKILNFYLGYMADVI
HHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TEYQGTIDEFMGDGILVLFGAPTYRGDDPTRAVACAIAMQLAMEPVNKQMKEWGLTPLEM
HHHHCCHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GIGINTGEVVVGNIGSWKRTKYGIVGNQVNLTYRIESYTTGGQILISETTLNEVGSIIKI
CCCCCCCCEEEECCCCCCCEEECEECCEEEEEEEEEEECCCCEEEEEECCHHHCCCEEEE
NGKKEVMPKGVKKPITIYDLGGIGGKYNLFLPKEEEIYLPLKEAISLHYVVLDGKNVSAC
CCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEEEEHHHCCEEEEEEEECCCCCCC
GQSGSLVKLSKKEAEIQVVNSGENIPHALINIKINFFWDGKESEDVYGKVLDKKAENGNF
CCCCCEEEEECCCCEEEEEECCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCE
YIHFTAKPPDVSAKLESLYKSLQT
EEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]