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The map label for this gene is typA [H]

Identifier: 113477841

GI number: 113477841

Start: 6846113

End: 6847903

Strand: Reverse

Name: typA [H]

Synonym: Tery_4442

Alternate gene names: 113477841

Gene position: 6847903-6846113 (Counterclockwise)

Preceding gene: 113477846

Following gene: 113477840

Centisome position: 88.36

GC content: 42.88

Gene sequence:

>1791_bases
ATGTCTCTTCCTATTCGCAACGTAGCCATCATCGCCCACGTTGACCACGGCAAAACTACCCTAGTAGACTCGCTCCTCAA
ACAATCTGGCATCTTCCGGGAAGGAGAAGAAGTTCCTGATTGTGTCATGGACTCCAACGACCTAGAAAGGGAACGTGGGA
TTACAATTCTTTCTAAAAATACCGCAGTTACATACAAAGATACTCTCATAAATATCGTCGATACTCCTGGTCACGCTGAC
TTTGGAGGAGAAGTAGAACGAGTTCTGGGTATGGTGGATGGTTGTTTACTAATTGTGGATGCCAATGAAGGCCCAATGCC
ACAAACTCGCTTCGTGCTCAAAAAAGCTCTAGAAAAAGGTTTACGGCCCATTGTTATTGTTAATAAAATCGACCGTCCCC
GAGTTAATCCCCACAGGGCTGTTGACAAAGTTCTTGACCTATTTATTGAACTAGGTGCAGATGATGACCAATGTGACTTT
CCTTATCTATTTGCCTCTGGTTTGGGAGGTTACGCGAAAAAAGACCTGGAAACGGAATCACAGGATATGCAGTGTTTATT
CGATGCTATTTTAGACCATGTGCCCCCTCCAGTGGGAGACCCTGAAAAATCTCTCCAGTTACAGGTGACTACTCTGGACT
ATTCAGAATATTTGGGCAGAATAGTGGTAGGTCGTATCCACAATGGTGTGATTAAATCTGGGCAACTAGCTGCTATTGTC
AAAGAAGATGGTACAATTGTTAAGTCAAAAATCTCAAAATTAATGGGATTCCAAGGTTTGGCACGCATTGACGTACAAGA
AGCTGCTGCTGGTAGTATTGTGGCAGTTGCTGGTTTTAGTGATGCTAATATTGGTGAAACTATTACTTGTCCTAACGAAC
CTCAAGCTCTACCTCTGATCAAAGTAGATGAACCGACTTTACAAATGACTTTCTCTGTAAATGATTCTCCATTTGCTGGT
AAGGAAGGAAAATTTGTAACTTCTCGGCAAGTACGCGATCGCCTGATGCGAGAGTTAGAAACTAATGTGGCATTACGAGT
AGAAGAAACTGACTCTCCAGAGAAGTTCTCTGTTTCAGGTCGTGGGGAATTGCACTTGGGTATTTTGATTGAAACTATGC
GCCGAGAAGGTTATGAGTTTCAAGTTTCTCAACCTCAAGTTATTTACCGGGAAATAAATGGTCAGCCATGCGAACCATTT
GAACTATTAGTGATGGATGTTCCCGAAGATGCTGTCGGTGGTTGCATCGAAAGAATAGGTCAGCGCAAAGGGGAAATGCA
GAATATGCAGGTGAGTACAAATGGTCGAACTCAGTTAGATTTTTCTGTTCCTGCTCGTGGTTTGATTGGTTTCCGGGGTG
AGTTTATGCGTCTTACCCGTGGGGAAGGCATTATGAATCACAGTTTTTTAGATTATCGTCCTTTAATTGGTGACATTGAA
GCTCGACGCAATGGAGTAATTATTGTATTTGAGGAAGGTGTGGCGACTTTTTATGCCTTGAAAAATGCTGAAGACCGTGG
AGTATTTTTCATTACCCCTGGTACAAAGGTTTATAAAGGTATGATTGTGGGAGAGCATAACCGCCCTCAAGATTTGGATT
TGAATGTTTGTAAAACTAAGCAGTTGACTAATCATCGTTCTGCAACTGGGGATGAGTTAGTGCAGTTACAAGCTCCTGTG
GAAATGAGCTTGGAGCGGGCGTTGGAATATATTGGGCCGGATGAGTTGGTTGAGATCACACCAGAGTCAATTCGGTTGCG
GAAGATGAGTAAAAAACTGGTCAAACGTTAA

Upstream 100 bases:

>100_bases
CTGACTAAGAACTTATGACTTACGGATAGCACCATAGTGCTTTAGATCAACTACAATAATTAAAGAAATCTAAAACCAAT
ATCCGTAATAAAAACTTCTT

Downstream 100 bases:

>100_bases
AGCAGTTAACATATGAACTCGAAAACTGATGACTAATAATTGAAATTGGCAGAATACTTTAGGAAAGCTTCACTACAAGT
ATTTGCCAGGACTTACGCAG

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MSLPIRNVAIIAHVDHGKTTLVDSLLKQSGIFREGEEVPDCVMDSNDLERERGITILSKNTAVTYKDTLINIVDTPGHAD
FGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVIVNKIDRPRVNPHRAVDKVLDLFIELGADDDQCDF
PYLFASGLGGYAKKDLETESQDMQCLFDAILDHVPPPVGDPEKSLQLQVTTLDYSEYLGRIVVGRIHNGVIKSGQLAAIV
KEDGTIVKSKISKLMGFQGLARIDVQEAAAGSIVAVAGFSDANIGETITCPNEPQALPLIKVDEPTLQMTFSVNDSPFAG
KEGKFVTSRQVRDRLMRELETNVALRVEETDSPEKFSVSGRGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPF
ELLVMDVPEDAVGGCIERIGQRKGEMQNMQVSTNGRTQLDFSVPARGLIGFRGEFMRLTRGEGIMNHSFLDYRPLIGDIE
ARRNGVIIVFEEGVATFYALKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVCKTKQLTNHRSATGDELVQLQAPV
EMSLERALEYIGPDELVEITPESIRLRKMSKKLVKR

Sequences:

>Translated_596_residues
MSLPIRNVAIIAHVDHGKTTLVDSLLKQSGIFREGEEVPDCVMDSNDLERERGITILSKNTAVTYKDTLINIVDTPGHAD
FGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVIVNKIDRPRVNPHRAVDKVLDLFIELGADDDQCDF
PYLFASGLGGYAKKDLETESQDMQCLFDAILDHVPPPVGDPEKSLQLQVTTLDYSEYLGRIVVGRIHNGVIKSGQLAAIV
KEDGTIVKSKISKLMGFQGLARIDVQEAAAGSIVAVAGFSDANIGETITCPNEPQALPLIKVDEPTLQMTFSVNDSPFAG
KEGKFVTSRQVRDRLMRELETNVALRVEETDSPEKFSVSGRGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPF
ELLVMDVPEDAVGGCIERIGQRKGEMQNMQVSTNGRTQLDFSVPARGLIGFRGEFMRLTRGEGIMNHSFLDYRPLIGDIE
ARRNGVIIVFEEGVATFYALKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVCKTKQLTNHRSATGDELVQLQAPV
EMSLERALEYIGPDELVEITPESIRLRKMSKKLVKR
>Mature_595_residues
SLPIRNVAIIAHVDHGKTTLVDSLLKQSGIFREGEEVPDCVMDSNDLERERGITILSKNTAVTYKDTLINIVDTPGHADF
GGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVIVNKIDRPRVNPHRAVDKVLDLFIELGADDDQCDFP
YLFASGLGGYAKKDLETESQDMQCLFDAILDHVPPPVGDPEKSLQLQVTTLDYSEYLGRIVVGRIHNGVIKSGQLAAIVK
EDGTIVKSKISKLMGFQGLARIDVQEAAAGSIVAVAGFSDANIGETITCPNEPQALPLIKVDEPTLQMTFSVNDSPFAGK
EGKFVTSRQVRDRLMRELETNVALRVEETDSPEKFSVSGRGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPFE
LLVMDVPEDAVGGCIERIGQRKGEMQNMQVSTNGRTQLDFSVPARGLIGFRGEFMRLTRGEGIMNHSFLDYRPLIGDIEA
RRNGVIIVFEEGVATFYALKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVCKTKQLTNHRSATGDELVQLQAPVE
MSLERALEYIGPDELVEITPESIRLRKMSKKLVKR

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=325, Percent_Identity=31.0769230769231, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI94966754, Length=157, Percent_Identity=39.4904458598726, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=43.448275862069, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI34147630, Length=241, Percent_Identity=33.195020746888, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=38.1944444444444, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI25306287, Length=142, Percent_Identity=38.7323943661972, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=42.7272727272727, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=42.7272727272727, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=42.7272727272727, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI19923640, Length=142, Percent_Identity=38.7323943661972, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI25306283, Length=142, Percent_Identity=38.7323943661972, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=41.044776119403, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=41.044776119403, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI94966752, Length=153, Percent_Identity=28.7581699346405, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI48994988, Length=587, Percent_Identity=53.6626916524702, Blast_Score=631, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=500, Percent_Identity=28.4, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=39.1891891891892, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=32.4137931034483, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1790412, Length=277, Percent_Identity=28.8808664259928, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789737, Length=277, Percent_Identity=28.8808664259928, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17557151, Length=230, Percent_Identity=33.4782608695652, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988811, Length=131, Percent_Identity=41.2213740458015, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=131, Percent_Identity=41.2213740458015, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=39.4366197183099, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=204, Percent_Identity=36.7647058823529, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=217, Percent_Identity=31.7972350230415, Blast_Score=102, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=35.8208955223881, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17556456, Length=289, Percent_Identity=30.1038062283737, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994658, Length=305, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141371, Length=259, Percent_Identity=28.1853281853282, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=521, Percent_Identity=29.5585412667946, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324707, Length=146, Percent_Identity=41.0958904109589, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320593, Length=146, Percent_Identity=41.0958904109589, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6324761, Length=274, Percent_Identity=29.9270072992701, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6322359, Length=148, Percent_Identity=38.5135135135135, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=39.5973154362416, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI78706572, Length=513, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=43.448275862069, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574573, Length=137, Percent_Identity=41.6058394160584, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24585711, Length=148, Percent_Identity=37.8378378378378, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585713, Length=148, Percent_Identity=37.8378378378378, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585709, Length=148, Percent_Identity=37.8378378378378, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363316, Length=273, Percent_Identity=29.6703296703297, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864358, Length=273, Percent_Identity=29.6703296703297, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357743, Length=192, Percent_Identity=38.5416666666667, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221458488, Length=147, Percent_Identity=40.8163265306122, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19921738, Length=277, Percent_Identity=28.5198555956679, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66077; Mature: 65946

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPIRNVAIIAHVDHGKTTLVDSLLKQSGIFREGEEVPDCVMDSNDLERERGITILSKN
CCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCEEEEECC
TAVTYKDTLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKG
CEEEEECEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVIVNKIDRPRVNPHRAVDKVLDLFIELGADDDQCDFPYLFASGLGGYAKKDLETES
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHCCCCCH
QDMQCLFDAILDHVPPPVGDPEKSLQLQVTTLDYSEYLGRIVVGRIHNGVIKSGQLAAIV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEHHHHHCCCCCCCCEEEEE
KEDGTIVKSKISKLMGFQGLARIDVQEAAAGSIVAVAGFSDANIGETITCPNEPQALPLI
ECCCCHHHHHHHHHHCCCCHHEEEHHHHCCCCEEEEECCCCCCCCCEEECCCCCCEEEEE
KVDEPTLQMTFSVNDSPFAGKEGKFVTSRQVRDRLMRELETNVALRVEETDSPEKFSVSG
EECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECC
RGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPFELLVMDVPEDAVGGCIERIG
CCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHH
QRKGEMQNMQVSTNGRTQLDFSVPARGLIGFRGEFMRLTRGEGIMNHSFLDYRPLIGDIE
HHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHH
ARRNGVIIVFEEGVATFYALKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVCKTK
CCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCHHEEEEEEECCCCCCCCCCEEECCH
QLTNHRSATGDELVQLQAPVEMSLERALEYIGPDELVEITPESIRLRKMSKKLVKR
HHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLPIRNVAIIAHVDHGKTTLVDSLLKQSGIFREGEEVPDCVMDSNDLERERGITILSKN
CCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCHHHCCEEEEECC
TAVTYKDTLINIVDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKG
CEEEEECEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHC
LRPIVIVNKIDRPRVNPHRAVDKVLDLFIELGADDDQCDFPYLFASGLGGYAKKDLETES
CCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHCCCCCH
QDMQCLFDAILDHVPPPVGDPEKSLQLQVTTLDYSEYLGRIVVGRIHNGVIKSGQLAAIV
HHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHEEHHHHHCCCCCCCCEEEEE
KEDGTIVKSKISKLMGFQGLARIDVQEAAAGSIVAVAGFSDANIGETITCPNEPQALPLI
ECCCCHHHHHHHHHHCCCCHHEEEHHHHCCCCEEEEECCCCCCCCCEEECCCCCCEEEEE
KVDEPTLQMTFSVNDSPFAGKEGKFVTSRQVRDRLMRELETNVALRVEETDSPEKFSVSG
EECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHCCCEEEEEECCCCCCEEEECC
RGELHLGILIETMRREGYEFQVSQPQVIYREINGQPCEPFELLVMDVPEDAVGGCIERIG
CCCEEEHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHH
QRKGEMQNMQVSTNGRTQLDFSVPARGLIGFRGEFMRLTRGEGIMNHSFLDYRPLIGDIE
HHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHH
ARRNGVIIVFEEGVATFYALKNAEDRGVFFITPGTKVYKGMIVGEHNRPQDLDLNVCKTK
CCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCCHHEEEEEEECCCCCCCCCCEEECCH
QLTNHRSATGDELVQLQAPVEMSLERALEYIGPDELVEITPESIRLRKMSKKLVKR
HHHCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]