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The map label for this gene is spkB [H]

Identifier: 113476913

GI number: 113476913

Start: 5206814

End: 5208517

Strand: Reverse

Name: spkB [H]

Synonym: Tery_3400

Alternate gene names: 113476913

Gene position: 5208517-5206814 (Counterclockwise)

Preceding gene: 113476917

Following gene: 113476912

Centisome position: 67.21

GC content: 37.32

Gene sequence:

>1704_bases
ATGACACAAGACCTTTCCAGTCACGGCTATGAAATTATTAGACAAGTGGAACGTCACCAACAAGAGGGAGAAGTGACATA
TCAGGGAATAGCTCTCAAGCAAAACCAAGAAGTTGTTATCAAAGAGTTCCGTTTTGCAGATGATAATGCTAATTGGACAA
TATTTGAAGCTTATGAGCGAGAAGTAGAAATTCTCAAACAACTACAACATCCCCGCATTCCTAACTATATTGATGCCCTA
GAAACTTCCGAAGGATTTTGTTTAATTACAAAATATCAAGAGGGAAAATCTTTGGCAGAAAGAAGAAGTTTTACCCCAGA
ACAAATTAAACAAATTGCTATTTCAATTTTAGAGATTTTAGTATATTTACAAAAGTGTAAACCGCCAATTATTCACGGCA
ATATTAAACCTGAAAATATATTAGTGACGACTCATATCAACGGTGAAAGATTTCCTACTGCATATTTAATGAATTTTGGT
TGCGCACGGAAGGGAATAGAAGAGAATTTTACTGATGGTGTCAGTGGGACATCAGGATTTATGCCTCCAGAACAAGAATT
GAATGGTACTGTCACTATCAATTCTGACTTATATAGTTTAGGGGTAACTATGATTTGCTTGCTGACAGGTACTTCTAGTA
GAGATGTAATTAAATTAATTGATCGCAATCATCGCTTTAACCTGAAAAAATTAGCGCCACAACTGAGTGTATTATTTACA
ATGTGGCTAGAGAAAATGGTATCTCCCAATGGTAAAGATCGCTTTGAAAATGCAGGAGCGGCTTTAGCAGCACTAAAACC
AATACCTGTTTTTGGCGATGCTGCTAATTTTAAGAATGTGGCAATGGCAATGTTACCTGTAAAAGCATCTGTCATATTGG
GATTCGCCAGTATTGCTGCTCTTTCTTTATTGGCGACAACTTTAACAGTTTTTCGTCAACAACCAAACTTAAGGAATTCC
CTGAATAAACAAAAACTTCAGTTGGAAAGAACAACAACAATATTGTCTGGTGACAACTCAGTTGCTAAATTGCGAGCAAC
TTCAGAATGTTACGGTTGTAACTTCCGTCGTGCTAATTTTGCAGCTCTCAAACTTGAAGATGCTTATTTGCGAAACGCAG
ATTTATTTCAAGCTAATTTAAGAGGTGTTGAACTCAGAGGTGCAAGATTACAAAATGCTAACCTTAAGAAGGCGCAATTG
CAAGGCTCAATTTTAATCAAGGCTAAACTCCAGAAAGCAAATTTGTATCGTGCTAGCTTAGAAGGTGCAAATTTAACTAA
GGCAGTTTTAGTCAGTGCTAACCTACGACGAGTGAATTTATCTGGCGCAAATTTGAACTCTACAAATTTGCGTGCTGCTA
ATTTTTCTGGTGCTTATCTCCGTGAGGCTAAATTGAGTAGGGCGAATTTAGAAGGAGCTAATTTAAAGAAAGCTAATTTA
AGTGGTGCAAATATGAGTCATGCTAGTCTCCGAGGTGCAGATTTGAGGAGGGCAACTTTAAAAGATGCTAATCTCAAGAG
GGTAGATTTAGTGGGAGCAAATTTAGCAGGGGTTACATTCCTGGATGCCGACCTTCAAGGAGCTAACTTGAAAGGAGCTA
ATCTAAAAAATGCTAATTTACTGGGTGCAAACTTAGAAAATGTAAATTTGCAAGGTGCTAATTTGCAAGGTGCAATTATG
CCTGATGGTAGTTTTATTGAGTAG

Upstream 100 bases:

>100_bases
AATTGCTAGTAAATCAAAAATATGATAGTATTTTAATAAAAATATAATTTTTTTATTAGCCCCCATTGATAAGCAAAAAA
AATACGGTGGTACTCTTAAT

Downstream 100 bases:

>100_bases
ATATTTGACTATTTCAGTTATCACTTATCGGTAATTCCTATTGAACCATATGGCGATTTTTCATCCCTCTAAAAGGGGAA
GCTTGGGAACTTAACTTTTG

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTQDLSSHGYEIIRQVERHQQEGEVTYQGIALKQNQEVVIKEFRFADDNANWTIFEAYEREVEILKQLQHPRIPNYIDAL
ETSEGFCLITKYQEGKSLAERRSFTPEQIKQIAISILEILVYLQKCKPPIIHGNIKPENILVTTHINGERFPTAYLMNFG
CARKGIEENFTDGVSGTSGFMPPEQELNGTVTINSDLYSLGVTMICLLTGTSSRDVIKLIDRNHRFNLKKLAPQLSVLFT
MWLEKMVSPNGKDRFENAGAALAALKPIPVFGDAANFKNVAMAMLPVKASVILGFASIAALSLLATTLTVFRQQPNLRNS
LNKQKLQLERTTTILSGDNSVAKLRATSECYGCNFRRANFAALKLEDAYLRNADLFQANLRGVELRGARLQNANLKKAQL
QGSILIKAKLQKANLYRASLEGANLTKAVLVSANLRRVNLSGANLNSTNLRAANFSGAYLREAKLSRANLEGANLKKANL
SGANMSHASLRGADLRRATLKDANLKRVDLVGANLAGVTFLDADLQGANLKGANLKNANLLGANLENVNLQGANLQGAIM
PDGSFIE

Sequences:

>Translated_567_residues
MTQDLSSHGYEIIRQVERHQQEGEVTYQGIALKQNQEVVIKEFRFADDNANWTIFEAYEREVEILKQLQHPRIPNYIDAL
ETSEGFCLITKYQEGKSLAERRSFTPEQIKQIAISILEILVYLQKCKPPIIHGNIKPENILVTTHINGERFPTAYLMNFG
CARKGIEENFTDGVSGTSGFMPPEQELNGTVTINSDLYSLGVTMICLLTGTSSRDVIKLIDRNHRFNLKKLAPQLSVLFT
MWLEKMVSPNGKDRFENAGAALAALKPIPVFGDAANFKNVAMAMLPVKASVILGFASIAALSLLATTLTVFRQQPNLRNS
LNKQKLQLERTTTILSGDNSVAKLRATSECYGCNFRRANFAALKLEDAYLRNADLFQANLRGVELRGARLQNANLKKAQL
QGSILIKAKLQKANLYRASLEGANLTKAVLVSANLRRVNLSGANLNSTNLRAANFSGAYLREAKLSRANLEGANLKKANL
SGANMSHASLRGADLRRATLKDANLKRVDLVGANLAGVTFLDADLQGANLKGANLKNANLLGANLENVNLQGANLQGAIM
PDGSFIE
>Mature_566_residues
TQDLSSHGYEIIRQVERHQQEGEVTYQGIALKQNQEVVIKEFRFADDNANWTIFEAYEREVEILKQLQHPRIPNYIDALE
TSEGFCLITKYQEGKSLAERRSFTPEQIKQIAISILEILVYLQKCKPPIIHGNIKPENILVTTHINGERFPTAYLMNFGC
ARKGIEENFTDGVSGTSGFMPPEQELNGTVTINSDLYSLGVTMICLLTGTSSRDVIKLIDRNHRFNLKKLAPQLSVLFTM
WLEKMVSPNGKDRFENAGAALAALKPIPVFGDAANFKNVAMAMLPVKASVILGFASIAALSLLATTLTVFRQQPNLRNSL
NKQKLQLERTTTILSGDNSVAKLRATSECYGCNFRRANFAALKLEDAYLRNADLFQANLRGVELRGARLQNANLKKAQLQ
GSILIKAKLQKANLYRASLEGANLTKAVLVSANLRRVNLSGANLNSTNLRAANFSGAYLREAKLSRANLEGANLKKANLS
GANMSHASLRGADLRRATLKDANLKRVDLVGANLAGVTFLDADLQGANLKGANLKNANLLGANLENVNLQGANLQGAIMP
DGSFIE

Specific function: Protein kinase required for cell motility, but not for phototaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI39753959, Length=168, Percent_Identity=37.5, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI162951881, Length=207, Percent_Identity=28.5024154589372, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI45643117, Length=208, Percent_Identity=29.3269230769231, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI120659787, Length=195, Percent_Identity=31.2820512820513, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI120659785, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI19923468, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI120659782, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI211971038, Length=167, Percent_Identity=29.3413173652695, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI211971036, Length=167, Percent_Identity=29.3413173652695, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI33636698, Length=168, Percent_Identity=30.3571428571429, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4557511, Length=162, Percent_Identity=32.7160493827161, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI5031689, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI115529463, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI89363047, Length=161, Percent_Identity=32.2981366459627, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI45439359, Length=157, Percent_Identity=31.8471337579618, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790502, Length=207, Percent_Identity=25.6038647342995, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193208795, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193208793, Length=195, Percent_Identity=28.7179487179487, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533600, Length=205, Percent_Identity=25.3658536585366, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321126, Length=164, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324557, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221377802, Length=166, Percent_Identity=41.566265060241, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161077548, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329689, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359801, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329687, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329683, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI62512112, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329681, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329685, Length=169, Percent_Identity=28.9940828402367, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648518, Length=182, Percent_Identity=29.1208791208791, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221379848, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45551927, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45551925, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45551923, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550768, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001646
- InterPro:   IPR020636
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR016252 [H]

Pfam domain/function: PF00805 Pentapeptide; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 62331; Mature: 62200

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDLSSHGYEIIRQVERHQQEGEVTYQGIALKQNQEVVIKEFRFADDNANWTIFEAYER
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEEECCCCCCEEEEHHHHH
EVEILKQLQHPRIPNYIDALETSEGFCLITKYQEGKSLAERRSFTPEQIKQIAISILEIL
HHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHH
VYLQKCKPPIIHGNIKPENILVTTHINGERFPTAYLMNFGCARKGIEENFTDGVSGTSGF
HHHHHCCCCEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCC
MPPEQELNGTVTINSDLYSLGVTMICLLTGTSSRDVIKLIDRNHRFNLKKLAPQLSVLFT
CCCHHHCCEEEEECCCHHHHHHHEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
MWLEKMVSPNGKDRFENAGAALAALKPIPVFGDAANFKNVAMAMLPVKASVILGFASIAA
HHHHHHHCCCCCHHHHHCCCEEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLLATTLTVFRQQPNLRNSLNKQKLQLERTTTILSGDNSVAKLRATSECYGCNFRRANF
HHHHHHHHHHHHCCCCHHHHCCHHHEEEEHHEEEEECCCCEEEEEECCHHHCCCCCCCCE
AALKLEDAYLRNADLFQANLRGVELRGARLQNANLKKAQLQGSILIKAKLQKANLYRASL
EEEEEEHHHHCCCHHHHHCCCCEEEECCEECCCCCCHHHCCCEEEEEEEECCCCEEEEEC
EGANLTKAVLVSANLRRVNLSGANLNSTNLRAANFSGAYLREAKLSRANLEGANLKKANL
CCCCCEEEEEEECCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEECCC
SGANMSHASLRGADLRRATLKDANLKRVDLVGANLAGVTFLDADLQGANLKGANLKNANL
CCCCCCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEE
LGANLENVNLQGANLQGAIMPDGSFIE
EECCCCCCEEECCCEEEEECCCCCCCC
>Mature Secondary Structure 
TQDLSSHGYEIIRQVERHQQEGEVTYQGIALKQNQEVVIKEFRFADDNANWTIFEAYER
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEEECCCCCCEEEEHHHHH
EVEILKQLQHPRIPNYIDALETSEGFCLITKYQEGKSLAERRSFTPEQIKQIAISILEIL
HHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHHHHHHHHHH
VYLQKCKPPIIHGNIKPENILVTTHINGERFPTAYLMNFGCARKGIEENFTDGVSGTSGF
HHHHHCCCCEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCC
MPPEQELNGTVTINSDLYSLGVTMICLLTGTSSRDVIKLIDRNHRFNLKKLAPQLSVLFT
CCCHHHCCEEEEECCCHHHHHHHEEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
MWLEKMVSPNGKDRFENAGAALAALKPIPVFGDAANFKNVAMAMLPVKASVILGFASIAA
HHHHHHHCCCCCHHHHHCCCEEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSLLATTLTVFRQQPNLRNSLNKQKLQLERTTTILSGDNSVAKLRATSECYGCNFRRANF
HHHHHHHHHHHHCCCCHHHHCCHHHEEEEHHEEEEECCCCEEEEEECCHHHCCCCCCCCE
AALKLEDAYLRNADLFQANLRGVELRGARLQNANLKKAQLQGSILIKAKLQKANLYRASL
EEEEEEHHHHCCCHHHHHCCCCEEEECCEECCCCCCHHHCCCEEEEEEEECCCCEEEEEC
EGANLTKAVLVSANLRRVNLSGANLNSTNLRAANFSGAYLREAKLSRANLEGANLKKANL
CCCCCEEEEEEECCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEECCC
SGANMSHASLRGADLRRATLKDANLKRVDLVGANLAGVTFLDADLQGANLKGANLKNANL
CCCCCCHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEE
LGANLENVNLQGANLQGAIMPDGSFIE
EECCCCCCEEECCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12732981; 8905231 [H]