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The map label for this gene is ubiB [C]

Identifier: 113476816

GI number: 113476816

Start: 5055023

End: 5057077

Strand: Reverse

Name: ubiB [C]

Synonym: Tery_3296

Alternate gene names: 113476816

Gene position: 5057077-5055023 (Counterclockwise)

Preceding gene: 113476819

Following gene: 113476815

Centisome position: 65.25

GC content: 34.7

Gene sequence:

>2055_bases
ATGAATTTAGAAACAATATCATCTGGAGCTCACCAAGAAGACTTCAATTCAAGTAGCCAAAAATTAGACATATTAGAAGT
TGAGGCAATGCAACTAAAAAATATAGATAGAGATACCCTTAAGTCTCAAAGTTCGACTCAGACAGCAGAAAGTAATACAA
ATACCCCACGTTATGATCCAGAAGTAATTACAGCCTTTTACAGTAAACGTCCTTTGCAAGTCTGGAAACGACGAATAGAT
ATATTATGGACCTTTGTCTTATTTGCTTTTAACTGGTGGTTGGACAAAGTTACTGGTAACGCCGCTAAAAATGAAAGAAA
AAGGGCAATCTGGTTAAGAGGAATTTTAACAAATCTGGGTCCTGCTTTTATTAAAGTAGGACAAGCTCTATCTACTCGAC
CAGATCTAGCTTCTCCAGTATATTTGGATGAGTTGACCAAATTACAAGACCAATTACCTGCTTTTCCCAATGAAGTAGCC
TATCATTTTATAGAAGAAGAATTAGGTTTTCCTCCAAAAGAAGTTTACGCAGAATTAACACCAGATCCTATAGCTGCTGC
TTCCCTTGGACAAGTATATAAAGGCAAATTAAAAACAGGTGAAATAGTAGCAGTAAAAGTACAGCGTCCTGGTTTAGCAG
AAAGCATTGCTTTAGACATTTATATATTAAGAACATTAGCTATTTGGGCAAATAAAAATATTCAGCGACTCCGTAGTGAC
TTAGTAGCTATAATGGATGAATTTGGGACTCGAATATTTGAGGAAATGGATTATACTCAAGAGGGTCGAAATGCTGAAAA
ATTTAAAGAGCTCTACGGTCATCTGAAAGATATTTATATTCCTAAAATTTATTGGCTATATACAGGTCGTCGTGTGTTGA
CGATGGAGTGGATAACGGGTACTAAGCTAACTAATTTGGAAGCTATAAAGGAAAAAAATATTGATGCGAAATATCTCATA
GAAATTGGTGTACAATGTTCTTTAAGACAGCTATTAGAACATGGTTTTTTTCATGCTGATCCTCATCCTGGTAATTTATT
AGCAAGTCCAGATGGTAAATTAGTTTACCTAGATTTTGGCATGATGAGTGAGGTTAAACCTTATCAGCGATATGGTTTAT
TAGAGGCAATTGTACACTTGGTAAATCGTGATTTTGAAGGTTTAGCTCAGGATTATGTAAAGCTCGAGTTTTTAACTCCA
GAAACAGATTTAACTCCTATTATTCCAGCATTAACTGGTGTTTTCAACAATGCTCTTGGTGCAAGTGTGGCAGAACTTAA
TTTTAAGAGTATTACAGACCAATTATCGGCTTTAATGTATGAGTATCCATTCCGTGTGCCTGCTTATTATGCTTTGATTA
TTCGCTCTTTGGTAACTTTAGAAGGTATTGCTATTAATGTCGATCCTAATTTTAAAGTATTGAGTAAAGCTTATCCTTAT
GTAGCTAAACGTTTATTAACTGACACTTCTCCTGAGTTGAGAAATTCTCTAAAAGATTTACTTTTTAAAGATGGCAATTT
TCGTTGGAATAGGTTAGAAAATCTTTTAAAAAATGCTAGTAATAGTGATGATTATGAGATTAGCAAAGTGTTAGATCAAG
CTCTAGATTTCTTATTATCTGAACGGGGAGATTTTATTCGAGTTCATTTAGTTAACGAGCTCATAAATGGTCTGGATTTG
GCATCAATAAATACATTGATTAACGCCAGAACTAAGGTAAGTAAGTGGTTAGGTATAAAAGTAGAAAAAACTTCAATTGC
TACATCTAGAAATCCCCAAGAAGAAAAGAGAACAGAACATATTAAAAATATCTGGAAAATTATTCAAGATACTCCTGGTT
TTGATGCTATGGAGTTAGTACAGTTGATACCAAATATATTAGGTAAACCAGAGATGCAAAGGATGGGGCAACAAGTAGCA
GGTGGTTTAACTCAACGGGCGCTTGCTCGTTTGATTCGTCAATTATTATTATCTCCGGAGCATCCTGATACTGATGGTAA
TAGTCATCAATCAAAAACTAAACCTCAACTTTCTTTACCTGCTTTTTTACCCTAG

Upstream 100 bases:

>100_bases
ACTTGTGGTATAAAGTATTACTTTTAACTTTTAACTTCCATGAAAAGGTAGGGATGTTGTTACAATATTTAATGACATTG
TTAAATTTTTCTAAAATTTT

Downstream 100 bases:

>100_bases
GTTGATATTGATTTGTTAATAGTTAATAGTTGGTTGTTAGTAACAAATTTTTCCACTAGCAACTAATTTTTTTATGGAAA
TATCACAAACATCAAAAGTA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MNLETISSGAHQEDFNSSSQKLDILEVEAMQLKNIDRDTLKSQSSTQTAESNTNTPRYDPEVITAFYSKRPLQVWKRRID
ILWTFVLFAFNWWLDKVTGNAAKNERKRAIWLRGILTNLGPAFIKVGQALSTRPDLASPVYLDELTKLQDQLPAFPNEVA
YHFIEEELGFPPKEVYAELTPDPIAAASLGQVYKGKLKTGEIVAVKVQRPGLAESIALDIYILRTLAIWANKNIQRLRSD
LVAIMDEFGTRIFEEMDYTQEGRNAEKFKELYGHLKDIYIPKIYWLYTGRRVLTMEWITGTKLTNLEAIKEKNIDAKYLI
EIGVQCSLRQLLEHGFFHADPHPGNLLASPDGKLVYLDFGMMSEVKPYQRYGLLEAIVHLVNRDFEGLAQDYVKLEFLTP
ETDLTPIIPALTGVFNNALGASVAELNFKSITDQLSALMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPY
VAKRLLTDTSPELRNSLKDLLFKDGNFRWNRLENLLKNASNSDDYEISKVLDQALDFLLSERGDFIRVHLVNELINGLDL
ASINTLINARTKVSKWLGIKVEKTSIATSRNPQEEKRTEHIKNIWKIIQDTPGFDAMELVQLIPNILGKPEMQRMGQQVA
GGLTQRALARLIRQLLLSPEHPDTDGNSHQSKTKPQLSLPAFLP

Sequences:

>Translated_684_residues
MNLETISSGAHQEDFNSSSQKLDILEVEAMQLKNIDRDTLKSQSSTQTAESNTNTPRYDPEVITAFYSKRPLQVWKRRID
ILWTFVLFAFNWWLDKVTGNAAKNERKRAIWLRGILTNLGPAFIKVGQALSTRPDLASPVYLDELTKLQDQLPAFPNEVA
YHFIEEELGFPPKEVYAELTPDPIAAASLGQVYKGKLKTGEIVAVKVQRPGLAESIALDIYILRTLAIWANKNIQRLRSD
LVAIMDEFGTRIFEEMDYTQEGRNAEKFKELYGHLKDIYIPKIYWLYTGRRVLTMEWITGTKLTNLEAIKEKNIDAKYLI
EIGVQCSLRQLLEHGFFHADPHPGNLLASPDGKLVYLDFGMMSEVKPYQRYGLLEAIVHLVNRDFEGLAQDYVKLEFLTP
ETDLTPIIPALTGVFNNALGASVAELNFKSITDQLSALMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPY
VAKRLLTDTSPELRNSLKDLLFKDGNFRWNRLENLLKNASNSDDYEISKVLDQALDFLLSERGDFIRVHLVNELINGLDL
ASINTLINARTKVSKWLGIKVEKTSIATSRNPQEEKRTEHIKNIWKIIQDTPGFDAMELVQLIPNILGKPEMQRMGQQVA
GGLTQRALARLIRQLLLSPEHPDTDGNSHQSKTKPQLSLPAFLP
>Mature_684_residues
MNLETISSGAHQEDFNSSSQKLDILEVEAMQLKNIDRDTLKSQSSTQTAESNTNTPRYDPEVITAFYSKRPLQVWKRRID
ILWTFVLFAFNWWLDKVTGNAAKNERKRAIWLRGILTNLGPAFIKVGQALSTRPDLASPVYLDELTKLQDQLPAFPNEVA
YHFIEEELGFPPKEVYAELTPDPIAAASLGQVYKGKLKTGEIVAVKVQRPGLAESIALDIYILRTLAIWANKNIQRLRSD
LVAIMDEFGTRIFEEMDYTQEGRNAEKFKELYGHLKDIYIPKIYWLYTGRRVLTMEWITGTKLTNLEAIKEKNIDAKYLI
EIGVQCSLRQLLEHGFFHADPHPGNLLASPDGKLVYLDFGMMSEVKPYQRYGLLEAIVHLVNRDFEGLAQDYVKLEFLTP
ETDLTPIIPALTGVFNNALGASVAELNFKSITDQLSALMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPY
VAKRLLTDTSPELRNSLKDLLFKDGNFRWNRLENLLKNASNSDDYEISKVLDQALDFLLSERGDFIRVHLVNELINGLDL
ASINTLINARTKVSKWLGIKVEKTSIATSRNPQEEKRTEHIKNIWKIIQDTPGFDAMELVQLIPNILGKPEMQRMGQQVA
GGLTQRALARLIRQLLLSPEHPDTDGNSHQSKTKPQLSLPAFLP

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=289, Percent_Identity=32.8719723183391, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI40254938, Length=244, Percent_Identity=29.9180327868852, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI217035081, Length=245, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI27363457, Length=295, Percent_Identity=27.7966101694915, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI217416386, Length=246, Percent_Identity=28.8617886178862, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI34147522, Length=286, Percent_Identity=27.972027972028, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI2367309, Length=409, Percent_Identity=28.361858190709, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=257, Percent_Identity=35.0194552529183, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=251, Percent_Identity=28.2868525896414, Blast_Score=92, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323282, Length=250, Percent_Identity=31.2, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=290, Percent_Identity=26.551724137931, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6325148, Length=529, Percent_Identity=21.7391304347826, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI22024280, Length=266, Percent_Identity=33.4586466165414, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24662575, Length=265, Percent_Identity=32.8301886792453, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI18859849, Length=251, Percent_Identity=27.8884462151394, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 77712; Mature: 77712

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLETISSGAHQEDFNSSSQKLDILEVEAMQLKNIDRDTLKSQSSTQTAESNTNTPRYDP
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCH
EVITAFYSKRPLQVWKRRIDILWTFVLFAFNWWLDKVTGNAAKNERKRAIWLRGILTNLG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
PAFIKVGQALSTRPDLASPVYLDELTKLQDQLPAFPNEVAYHFIEEELGFPPKEVYAELT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCC
PDPIAAASLGQVYKGKLKTGEIVAVKVQRPGLAESIALDIYILRTLAIWANKNIQRLRSD
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVAIMDEFGTRIFEEMDYTQEGRNAEKFKELYGHLKDIYIPKIYWLYTGRRVLTMEWITG
HHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEEEECC
TKLTNLEAIKEKNIDAKYLIEIGVQCSLRQLLEHGFFHADPHPGNLLASPDGKLVYLDFG
CCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECC
MMSEVKPYQRYGLLEAIVHLVNRDFEGLAQDYVKLEFLTPETDLTPIIPALTGVFNNALG
CHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHC
ASVAELNFKSITDQLSALMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPY
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
VAKRLLTDTSPELRNSLKDLLFKDGNFRWNRLENLLKNASNSDDYEISKVLDQALDFLLS
HHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ERGDFIRVHLVNELINGLDLASINTLINARTKVSKWLGIKVEKTSIATSRNPQEEKRTEH
CCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCCCHHHHHHHH
IKNIWKIIQDTPGFDAMELVQLIPNILGKPEMQRMGQQVAGGLTQRALARLIRQLLLSPE
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
HPDTDGNSHQSKTKPQLSLPAFLP
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLETISSGAHQEDFNSSSQKLDILEVEAMQLKNIDRDTLKSQSSTQTAESNTNTPRYDP
CCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCH
EVITAFYSKRPLQVWKRRIDILWTFVLFAFNWWLDKVTGNAAKNERKRAIWLRGILTNLG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
PAFIKVGQALSTRPDLASPVYLDELTKLQDQLPAFPNEVAYHFIEEELGFPPKEVYAELT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHCC
PDPIAAASLGQVYKGKLKTGEIVAVKVQRPGLAESIALDIYILRTLAIWANKNIQRLRSD
CCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LVAIMDEFGTRIFEEMDYTQEGRNAEKFKELYGHLKDIYIPKIYWLYTGRRVLTMEWITG
HHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEECCEEEEEEEECC
TKLTNLEAIKEKNIDAKYLIEIGVQCSLRQLLEHGFFHADPHPGNLLASPDGKLVYLDFG
CCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCEEEEECC
MMSEVKPYQRYGLLEAIVHLVNRDFEGLAQDYVKLEFLTPETDLTPIIPALTGVFNNALG
CHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHC
ASVAELNFKSITDQLSALMYEYPFRVPAYYALIIRSLVTLEGIAINVDPNFKVLSKAYPY
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
VAKRLLTDTSPELRNSLKDLLFKDGNFRWNRLENLLKNASNSDDYEISKVLDQALDFLLS
HHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ERGDFIRVHLVNELINGLDLASINTLINARTKVSKWLGIKVEKTSIATSRNPQEEKRTEH
CCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCCCCHHHHHHHH
IKNIWKIIQDTPGFDAMELVQLIPNILGKPEMQRMGQQVAGGLTQRALARLIRQLLLSPE
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
HPDTDGNSHQSKTKPQLSLPAFLP
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]