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The map label for this gene is ykcC [H]

Identifier: 113476755

GI number: 113476755

Start: 4937986

End: 4938924

Strand: Reverse

Name: ykcC [H]

Synonym: Tery_3225

Alternate gene names: 113476755

Gene position: 4938924-4937986 (Counterclockwise)

Preceding gene: 113476756

Following gene: 113476754

Centisome position: 63.73

GC content: 30.99

Gene sequence:

>939_bases
ATGAAATATATTGATTATTCTGTAGTTATTCCCATTTTTAATGAATCAGAAATTATCCCTGAGCTGTGGCGCAGATTATC
AGATATTTTAGACAAACTTGATAGCAGCAGTGAAGTAATTTTCATCAATGATGGAAGTGTAGATAATTCTTTAGAATTAC
TAAAAGAAATAAACCATAAAAATCAAAAAGTCAAAATTATTAGCTTTTCCAGAAACTTCGGTCATCAATGTGCTTTATCT
GCTGGAATAGATCATGCTAATGGTAAAGCAGTTATTCTTATGGATGGAGATTTACAAGATTCTCCAGAAGCAATTATCAG
TTTTTTGAGGCTTTGGCAACAGGGATATGATGTAGTATATGCCATTAGAAAAAATCGCAAAGAAAAATGGTTAAAACGAT
TAGCATTTAAAAGCTTTTATTACATCCAAAGAAAGTTGTCAGGAATTGTAACTCCCATGGATGCAGGAATCTTTTCATTA
ATGGATAGAAAAGTGATTCTAACCTTACGGCAAATGCCAGAACGCAATAAATATTTAAGTGGTTTAAGAGCTTATGCTGG
ATTTAAACAAATAGGAGTTTATGTAGAAAGAGGACCACGATATAGGGGTGAGCCAAAAATGTCAGTTTCTAAATTATTTA
AACTTGCTTTTGATGGCATATTTTCTTTTTCTACAATTCCTCTAAAAATGGCAACTATTTTAGGTTTAGTCTCAGCAATT
TTATCTTTTATTATTGGCTTAATTGGTCTTTACGTTAAATTTATTTTAGGAAAAGAATTTCTCTCCTGGGCTTATGGTTT
AACTACTACATTTTTTATGGGAGGAATTCAACTACTTTCTTTAGGAATTATTGGAGAATATATAGGTAGAATTTATGATG
AAGTTCGGCAAAGACCTTACTATATTATTCAGGAAAAAATTGGCTTTGAGAAACAATGA

Upstream 100 bases:

>100_bases
TATATAATCTTTATTCCTTGATTATAAATTATATTAATTATGCTTAGGTTGACAATCATAAAAAAAATTTGTATTATTGT
TAAAATAGTTAGTAAATACG

Downstream 100 bases:

>100_bases
TTAAGACAGAAAAAAATACTCAATCATAATTTTAAAATTTTACATTAGATAGTCATAGGTTTAGTCAACAGCCAGCAGTT
ATAATTAGAATATTAATTCT

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHKNQKVKIISFSRNFGHQCALS
AGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVYAIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSL
MDRKVILTLRQMPERNKYLSGLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAI
LSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPYYIIQEKIGFEKQ

Sequences:

>Translated_312_residues
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHKNQKVKIISFSRNFGHQCALS
AGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVYAIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSL
MDRKVILTLRQMPERNKYLSGLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAI
LSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPYYIIQEKIGFEKQ
>Mature_312_residues
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHKNQKVKIISFSRNFGHQCALS
AGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVYAIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSL
MDRKVILTLRQMPERNKYLSGLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAI
LSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPYYIIQEKIGFEKQ

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=299, Percent_Identity=39.1304347826087, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1788588, Length=309, Percent_Identity=32.6860841423948, Blast_Score=181, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24585265, Length=121, Percent_Identity=32.2314049586777, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 35780; Mature: 35780

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHK
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCC
NQKVKIISFSRNFGHQCALSAGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVY
CCEEEEEEECCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEH
AIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSLMDRKVILTLRQMPERNKYLS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAI
HHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YIIQEKIGFEKQ
EEEHHHCCCCCC
>Mature Secondary Structure
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHK
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCC
NQKVKIISFSRNFGHQCALSAGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVY
CCEEEEEEECCCCCCHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEH
AIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSLMDRKVILTLRQMPERNKYLS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAI
HHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
YIIQEKIGFEKQ
EEEHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]