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The map label for this gene is trpC

Identifier: 113476709

GI number: 113476709

Start: 4837154

End: 4838047

Strand: Reverse

Name: trpC

Synonym: Tery_3169

Alternate gene names: 113476709

Gene position: 4838047-4837154 (Counterclockwise)

Preceding gene: 113476710

Following gene: 113476708

Centisome position: 62.43

GC content: 32.66

Gene sequence:

>894_bases
ATGCAAATTCGTCGCCGTCCGCCAAACCCAGCGGTAGAAATGGGCACTTTACGCTATGAGGTTTCCGTGCCAGAGTCAAA
GCCTAAAAATATTCTAGAGGAAATAGTTTGGCATAAGGAAAAAGAGGTAGATTATTTGCGTGACAAAGAACCTTTAGTTG
AGTTAAGAAAAAAGATTAACTTAATGCCTCCTCCTCTGGATTTTTTGACTACATTATCAACAGGAAAAACTCAACTTGCT
GTAATAGCTGAAGTGAAAAAAGCTTCTCCTAGTAAAGGAGTAATTAGACAAGATTTTGAACCAGTTGCTATTGCTAAGTT
ATATCAGGAAAATGCTGCAACTTGTATCTCAGTTTTAACAGATAGAAAGTTCTTTCAAGGTAGTTTTGAAAATTTGGCAA
ATATTAGGGAAAATGTTGATTTACCATTACTTTGTAAAGACTTCCTAATTTATCCATATCAAATATACTTTGCTCGCTTA
TATGGAGCTGATGCTGTGCTATTAATAGCAGCAATTTTATCAGACCAAGACTTAAAATATTTTATCAAAATAGTTAATTC
TTTAGGAATGACAGCATTAGTTGAAGTTCATACTTTGAAAGAATTAGATCGGGTATTAGGAATAGAAGGGGTTAAGTTAA
TTGGTATAAATAATCGCAACTTAGAAGATTTTTCAGTGGATTTACAAACAACTTTTCAACTGATGGAAGCTAGAAAGAAA
GAATTAGAAAAACTCGGAATTTTAGTTGTAAGTGAATCTGGAATACATAGTTATGAAGATATCAATTTTATGATAAACGC
TGGTGTAAATGCTGTTTTAGTAGGAGAGTCTTTAGTCAAAAAAACAAATCCAGGTACAGCATTGCTACAACTATTTAATG
AAAATAAAAGTTAA

Upstream 100 bases:

>100_bases
TTGTTAGGAAATTGGTGACTTGAATAATCTCAACATTGCTAAATATTGAAAAAGCTGAAAAGTATCAAGTAAATATAATC
AAGTAATTTATTTAAAATAA

Downstream 100 bases:

>100_bases
AAGCTATGTCTATTTGTAATATTTAAATATGTTATAGAAGTATTTTTACTTACTTCTTATAAAAGAATATTTATGTTTTT
CGTTAGGAAAAATTGAGGTG

Product: indole-3-glycerol phosphate synthase

Products: NA

Alternate protein names: IGPS

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKINLMPPPLDFLTTLSTGKTQLA
VIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLTDRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARL
YGADAVLLIAAILSDQDLKYFIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKK
ELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS

Sequences:

>Translated_297_residues
MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKINLMPPPLDFLTTLSTGKTQLA
VIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLTDRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARL
YGADAVLLIAAILSDQDLKYFIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKK
ELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS
>Mature_297_residues
MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKINLMPPPLDFLTTLSTGKTQLA
VIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLTDRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARL
YGADAVLLIAAILSDQDLKYFIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKK
ELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family

Homologues:

Organism=Escherichia coli, GI87081863, Length=271, Percent_Identity=39.8523985239852, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322638, Length=233, Percent_Identity=42.0600858369099, Blast_Score=153, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPC_TRIEI (Q10ZM7)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722770.1
- ProteinModelPortal:   Q10ZM7
- SMR:   Q10ZM7
- STRING:   Q10ZM7
- GeneID:   4243840
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_3169
- NMPDR:   fig|203124.1.peg.147
- eggNOG:   COG0134
- HOGENOM:   HBG540956
- OMA:   VDLPLLC
- PhylomeDB:   Q10ZM7
- BioCyc:   TERY203124:TERY_3169-MONOMER
- HAMAP:   MF_00134_B
- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF00218 IGPS; SSF51366 RibP_bind_barrel

EC number: =4.1.1.48

Molecular weight: Translated: 33522; Mature: 33522

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKIN
CCCCCCCCCCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHCC
LMPPPLDFLTTLSTGKTQLAVIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLT
CCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
DRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARLYGADAVLLIAAILSDQDLKY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
FIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS
HHHHHCEEEEECCCCCCHHCCEEEEECCCCEEEECHHHHHCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MQIRRRPPNPAVEMGTLRYEVSVPESKPKNILEEIVWHKEKEVDYLRDKEPLVELRKKIN
CCCCCCCCCCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHCC
LMPPPLDFLTTLSTGKTQLAVIAEVKKASPSKGVIRQDFEPVAIAKLYQENAATCISVLT
CCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
DRKFFQGSFENLANIRENVDLPLLCKDFLIYPYQIYFARLYGADAVLLIAAILSDQDLKY
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
FIKIVNSLGMTALVEVHTLKELDRVLGIEGVKLIGINNRNLEDFSVDLQTTFQLMEARKK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELEKLGILVVSESGIHSYEDINFMINAGVNAVLVGESLVKKTNPGTALLQLFNENKS
HHHHHCEEEEECCCCCCHHCCEEEEECCCCEEEECHHHHHCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA