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The map label for this gene is ffh [H]

Identifier: 113476149

GI number: 113476149

Start: 3912586

End: 3914037

Strand: Direct

Name: ffh [H]

Synonym: Tery_2535

Alternate gene names: 113476149

Gene position: 3912586-3914037 (Clockwise)

Preceding gene: 113476145

Following gene: 113476150

Centisome position: 50.48

GC content: 43.8

Gene sequence:

>1452_bases
ATGTTTGAAGCTCTTGCTGACCGCTTAGAAGTGGCCTGGAAAAAACTAAGGGGTCAAGACAAAATAACAGATTCTAATAT
CCAACAAGCCCTGGGAGAAGTACGTCGAGCCCTGTTAGAGGCAGACGTCAACTTACAAGTTGTGAAAGGCTTTATAGCGG
AAGTCAGCAGTAAGGCAAAAGGAGCAGATGTATTAACAGGAGTAAGACCAGACCAACAGTTCATAAAAATCGTCCATGAT
GAACTAGCGCAGATAATGGGAGAAAGTAATGCTCCCCTAGCGAAAGCCGACCAACCGCCAACTATTGTCCTGATGGCAGG
TTTACAGGGAACAGGAAAAACCACAGCCTCAGCTAAGTTAGCCTTACATTTAAGGAAAGAGAACCGGAGTGCTTTACTGG
TAGCTACTGATGTCTATAGACCGGCTGCTATTGACCAGTTAGTTACCTTAGGAAAACAGATAGATGTACCCGTATTTGAA
TTAGGTACAGATATAGACCCTGTAGAAATTGCTCAGAAAGGGTTGGAAAAGGCCAAGGCAGATGGTATAGATATAGTAAT
TATAGATACAGCAGGTCGGCTACAGATAGACCAAGATATGATGGCAGAACTTGCTAGAATTAAAGCAGCAGTTAAGCCTC
AAGAAACCTTGCTAGTAGTAGATGCAATGACAGGTCAAGAGGCTGCAACATTGACCCGTACCTTCAATGATCAAATTGGG
ATAACAGGGGCGATCCTAACTAAAATGGACGGAGATACAAGAGGAGGGGCAGCTTTATCAGTCCGTAGAATTTCTGGTCA
ACCGATAAAATTTATAGGGGTGGGAGAAAAAGTAGAAGCCCTACAACCTTTCTACCCAGAAAGGATGGCTTCTAGGATTT
TGGGAATGGGAGATGTACTTACCCTGGTAGAAAAGGCTCAGGAAGAGTTTGACATAGCTGATGCAGAAAAAATGCAGGAA
AAAATCCTCTCAGCTAAGTTTGACTTTACTGACTTCCTCAAGCAAACGCGACTGATGAAGAATATGGGTTCCTTGGGAGG
AATTATGAAATTAATTCCAGGAATGAATAAAATAAGTGATGATAAGTTGCAGCAGGGAGAAACTCAGCTAAAACGTTGTG
AGTCTATGATTAATTCTATGACGCGCCAAGAGCGCCAAAATCCCGAACTTTTAGCGAAATCTCCTTCCCGACGACGACGC
ATTGCTGGTGGTTCAGGTTATGCTGAGAAAGATGTGAGTAAACTAGTGAGTGACTTCCAAAGAATGCGATCGCTGATGCA
GAAAATGGGCCAAGGCGATCTATCAGGGATGGGGATGCCTGGAATGCCTGGTATGGGAATGCCTGGTATGCTAGGAGGTA
AAGCACCTCCTGGTTGGCGTAACCAGCAAAGTACGGGTAGCGGTAAAAAGAAAAAGAAGCAGAAAAAGAAAAAAGGCTTT
GGGCAGCTTTAA

Upstream 100 bases:

>100_bases
ATGCAAAGATAAACAATAAAAATAATATGAAAAAAACATAGAAAAAGTTTTCCCAATGATATATAATAAAGATTTACTAC
TAGCTAGCTGAAATTGCTCT

Downstream 100 bases:

>100_bases
AAGAGGAGCAAAAACAAAAGCTGAAGTATCACCCAGATATGCTTAAAACATACATGCTTTTTTCAAAATTTCTTATGGTA
GATGTTCAAGAAGCATTTTA

Product: signal recognition particle subunit FFH/SRP54 (srp54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MFEALADRLEVAWKKLRGQDKITDSNIQQALGEVRRALLEADVNLQVVKGFIAEVSSKAKGADVLTGVRPDQQFIKIVHD
ELAQIMGESNAPLAKADQPPTIVLMAGLQGTGKTTASAKLALHLRKENRSALLVATDVYRPAAIDQLVTLGKQIDVPVFE
LGTDIDPVEIAQKGLEKAKADGIDIVIIDTAGRLQIDQDMMAELARIKAAVKPQETLLVVDAMTGQEAATLTRTFNDQIG
ITGAILTKMDGDTRGGAALSVRRISGQPIKFIGVGEKVEALQPFYPERMASRILGMGDVLTLVEKAQEEFDIADAEKMQE
KILSAKFDFTDFLKQTRLMKNMGSLGGIMKLIPGMNKISDDKLQQGETQLKRCESMINSMTRQERQNPELLAKSPSRRRR
IAGGSGYAEKDVSKLVSDFQRMRSLMQKMGQGDLSGMGMPGMPGMGMPGMLGGKAPPGWRNQQSTGSGKKKKKQKKKKGF
GQL

Sequences:

>Translated_483_residues
MFEALADRLEVAWKKLRGQDKITDSNIQQALGEVRRALLEADVNLQVVKGFIAEVSSKAKGADVLTGVRPDQQFIKIVHD
ELAQIMGESNAPLAKADQPPTIVLMAGLQGTGKTTASAKLALHLRKENRSALLVATDVYRPAAIDQLVTLGKQIDVPVFE
LGTDIDPVEIAQKGLEKAKADGIDIVIIDTAGRLQIDQDMMAELARIKAAVKPQETLLVVDAMTGQEAATLTRTFNDQIG
ITGAILTKMDGDTRGGAALSVRRISGQPIKFIGVGEKVEALQPFYPERMASRILGMGDVLTLVEKAQEEFDIADAEKMQE
KILSAKFDFTDFLKQTRLMKNMGSLGGIMKLIPGMNKISDDKLQQGETQLKRCESMINSMTRQERQNPELLAKSPSRRRR
IAGGSGYAEKDVSKLVSDFQRMRSLMQKMGQGDLSGMGMPGMPGMGMPGMLGGKAPPGWRNQQSTGSGKKKKKQKKKKGF
GQL
>Mature_483_residues
MFEALADRLEVAWKKLRGQDKITDSNIQQALGEVRRALLEADVNLQVVKGFIAEVSSKAKGADVLTGVRPDQQFIKIVHD
ELAQIMGESNAPLAKADQPPTIVLMAGLQGTGKTTASAKLALHLRKENRSALLVATDVYRPAAIDQLVTLGKQIDVPVFE
LGTDIDPVEIAQKGLEKAKADGIDIVIIDTAGRLQIDQDMMAELARIKAAVKPQETLLVVDAMTGQEAATLTRTFNDQIG
ITGAILTKMDGDTRGGAALSVRRISGQPIKFIGVGEKVEALQPFYPERMASRILGMGDVLTLVEKAQEEFDIADAEKMQE
KILSAKFDFTDFLKQTRLMKNMGSLGGIMKLIPGMNKISDDKLQQGETQLKRCESMINSMTRQERQNPELLAKSPSRRRR
IAGGSGYAEKDVSKLVSDFQRMRSLMQKMGQGDLSGMGMPGMPGMGMPGMLGGKAPPGWRNQQSTGSGKKKKKQKKKKGF
GQL

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=435, Percent_Identity=31.0344827586207, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI226371618, Length=348, Percent_Identity=32.183908045977, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI89061728, Length=160, Percent_Identity=36.25, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI23308697, Length=298, Percent_Identity=27.5167785234899, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI295424842, Length=298, Percent_Identity=27.5167785234899, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1788963, Length=454, Percent_Identity=49.1189427312775, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789874, Length=255, Percent_Identity=35.2941176470588, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=431, Percent_Identity=29.0023201856148, Blast_Score=224, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI193206261, Length=294, Percent_Identity=29.2517006802721, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325345, Length=458, Percent_Identity=32.7510917030568, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6320498, Length=314, Percent_Identity=24.8407643312102, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647949, Length=443, Percent_Identity=31.3769751693002, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=26.2458471760797, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 52576; Mature: 52576

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEALADRLEVAWKKLRGQDKITDSNIQQALGEVRRALLEADVNLQVVKGFIAEVSSKAK
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GADVLTGVRPDQQFIKIVHDELAQIMGESNAPLAKADQPPTIVLMAGLQGTGKTTASAKL
CCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEE
ALHLRKENRSALLVATDVYRPAAIDQLVTLGKQIDVPVFELGTDIDPVEIAQKGLEKAKA
EEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHC
DGIDIVIIDTAGRLQIDQDMMAELARIKAAVKPQETLLVVDAMTGQEAATLTRTFNDQIG
CCCEEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
ITGAILTKMDGDTRGGAALSVRRISGQPIKFIGVGEKVEALQPFYPERMASRILGMGDVL
CCCCEEEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHHH
TLVEKAQEEFDIADAEKMQEKILSAKFDFTDFLKQTRLMKNMGSLGGIMKLIPGMNKISD
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DKLQQGETQLKRCESMINSMTRQERQNPELLAKSPSRRRRIAGGSGYAEKDVSKLVSDFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHH
RMRSLMQKMGQGDLSGMGMPGMPGMGMPGMLGGKAPPGWRNQQSTGSGKKKKKQKKKKGF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
GQL
CCC
>Mature Secondary Structure
MFEALADRLEVAWKKLRGQDKITDSNIQQALGEVRRALLEADVNLQVVKGFIAEVSSKAK
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
GADVLTGVRPDQQFIKIVHDELAQIMGESNAPLAKADQPPTIVLMAGLQGTGKTTASAKL
CCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEE
ALHLRKENRSALLVATDVYRPAAIDQLVTLGKQIDVPVFELGTDIDPVEIAQKGLEKAKA
EEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHC
DGIDIVIIDTAGRLQIDQDMMAELARIKAAVKPQETLLVVDAMTGQEAATLTRTFNDQIG
CCCEEEEEECCCCEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
ITGAILTKMDGDTRGGAALSVRRISGQPIKFIGVGEKVEALQPFYPERMASRILGMGDVL
CCCCEEEECCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHCCCCHHHHHHHHHCCHHHH
TLVEKAQEEFDIADAEKMQEKILSAKFDFTDFLKQTRLMKNMGSLGGIMKLIPGMNKISD
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DKLQQGETQLKRCESMINSMTRQERQNPELLAKSPSRRRRIAGGSGYAEKDVSKLVSDFQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHH
RMRSLMQKMGQGDLSGMGMPGMPGMGMPGMLGGKAPPGWRNQQSTGSGKKKKKQKKKKGF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
GQL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]