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The map label for this gene is ubiB [C]

Identifier: 113476130

GI number: 113476130

Start: 3878566

End: 3880275

Strand: Direct

Name: ubiB [C]

Synonym: Tery_2512

Alternate gene names: 113476130

Gene position: 3878566-3880275 (Clockwise)

Preceding gene: 113476129

Following gene: 113476131

Centisome position: 50.05

GC content: 37.54

Gene sequence:

>1710_bases
GTGGGGCAAAATCACCTTAGTTCAACAAGACGGTACGATCCAGAAGCGATCGCTAAGTACTATTATTATCGTCTTTGGTT
AGTAATGTGGAGATTTCTGGTTATCTTCTTTTCTTTTACCAGTTTTGTTTTAGGAATTTTGTGGGACAAATGGCGATATA
AAAAAGTTGAAGATACCCCTGAGAGAGCAACTCAACTGCGAAAAATACTAACCAACTTAGGACCAACATTTATTAAAGTA
GGTCAAGCACTATCCACAAGACCAGATTTAATTCGTAAGGACTTCTTAGAAGAACTAACAAAACTGCAAGATCAGTTACC
AGCTTTTGATAATCAGATAGCCATCTCAATTATAGAGACAGAACTAGGCCAAAATATTAACGATATATATAGAGAAGTTT
CTCCCAGACCAGTTGCAGCAGCTAGTCTAGGTCAAGTTTATAAGGCACGCCTTCAGAGCGGCGAAAGTGTAGCAATAAAA
GTTCAACGACCCAACTTACTGCCAATTATAACTCTTGATTTATTCTTAATGCGGTGGGGAGCAAGTTGGTTATCTCCCTG
GTTGCCTTTAAATCTCGGCCATGATTTATCCCTAATTGTAGATGAATTTGGCACAAAACTATTTGAAGAAATTGACTATA
TAAACGAAGGGCATAACGCAGAAAGATTTGCTACCTATTTCGCAGATGACCCAAGTGTCAAAGTACCATCAATATATTGG
CATTATACTACTACCAATGTTTTGACCCTAGAATGGATTGATGGTCTAAAATTATTAGATACAAAACAAATTCAAGGAGC
AGGTCTTAATACTGATACCCTAATCACAGCAGGTGTAACTAGCGGTTTACGTCAATTACTAGAGTTTGGCTTTTTTCATG
CAGATCCCCATCCCGGTAACTTATTTGCCTTAACAGATGGTCGAATGGCCTACATTGATTTTGGCATGATGGATCAATTG
GAGCAAGATATTAAAGAAACCTTGGTTGACTCAGTAATTCATTTAATCAATAAAGACTATCAGGAGTTGGCTAAAGATTT
TGTCAAGCTTGGTTTTTTGGCACCTGATGCAGATATTCAGCCAATTATACCAGCTCTAGAAATGGTGCTGGGCAATATTA
TGGGTGAGAAAGTTAAAGATTTTAACTTTAAGACAATTACAGATAAGTTCTCAGAGTTAATGTATGAATATCCTTTCCGG
GTACCTGCTAAGTTTGCTCTAATTATTCGTTCTCTAGTTACTGAAGAGGGATTAGCTCTTTCCCTAAATCCAAATTTCAA
AATTGTAGATGTCGCTTATCCTTATGTAGCGAGAAGGTTATTAAAAGGTGAGTCCCCTGGCTTACGTCGGCGTTTGATTG
AGGTATTGTTTAAAGATGGAAAGTTTCAGTGGCAAAGGTTAGAAAACTTGATTGGCATAGCTCGAACAGACCAAAATTTT
GATATATTACCTACTGCCCAATTAGGTTTACAATATCTTTTGAGCGAAGAAGGTGAATTTCTCCGAAAACAATTAATACT
AGCAATAATAGAAGATGATCGGATTCACACAGAAGAAGTTAGTCGTTTGTGGGATTTAATTCAAGATGATTTACAACCAA
GTCGTTTGTTTAATTTTGCCCTGGGCGCTCTAGCAGAGTTTTCTACACAGAGAGCAGCGGCAATTTTACCCTCTGTCATG
GCCACAACAAATTCTCAAGCAAAGAATTAG

Upstream 100 bases:

>100_bases
TGAGTTTTCAGTGTTGAGTTTTACAAATGGCTATACCTTCTGAATTACTGAAAATTTACCATTAAAAAAAATATAAAATT
ATAAGAGGAAAATATTAAAA

Downstream 100 bases:

>100_bases
GACTCAAAACATAGAAACTGGGGAAAGTATTAGATACTCTATCATACCGATATTTATTTGTATCTCACAAACCCAGTTTC
TGATAAAATCCTACTTACAA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MGQNHLSSTRRYDPEAIAKYYYYRLWLVMWRFLVIFFSFTSFVLGILWDKWRYKKVEDTPERATQLRKILTNLGPTFIKV
GQALSTRPDLIRKDFLEELTKLQDQLPAFDNQIAISIIETELGQNINDIYREVSPRPVAAASLGQVYKARLQSGESVAIK
VQRPNLLPIITLDLFLMRWGASWLSPWLPLNLGHDLSLIVDEFGTKLFEEIDYINEGHNAERFATYFADDPSVKVPSIYW
HYTTTNVLTLEWIDGLKLLDTKQIQGAGLNTDTLITAGVTSGLRQLLEFGFFHADPHPGNLFALTDGRMAYIDFGMMDQL
EQDIKETLVDSVIHLINKDYQELAKDFVKLGFLAPDADIQPIIPALEMVLGNIMGEKVKDFNFKTITDKFSELMYEYPFR
VPAKFALIIRSLVTEEGLALSLNPNFKIVDVAYPYVARRLLKGESPGLRRRLIEVLFKDGKFQWQRLENLIGIARTDQNF
DILPTAQLGLQYLLSEEGEFLRKQLILAIIEDDRIHTEEVSRLWDLIQDDLQPSRLFNFALGALAEFSTQRAAAILPSVM
ATTNSQAKN

Sequences:

>Translated_569_residues
MGQNHLSSTRRYDPEAIAKYYYYRLWLVMWRFLVIFFSFTSFVLGILWDKWRYKKVEDTPERATQLRKILTNLGPTFIKV
GQALSTRPDLIRKDFLEELTKLQDQLPAFDNQIAISIIETELGQNINDIYREVSPRPVAAASLGQVYKARLQSGESVAIK
VQRPNLLPIITLDLFLMRWGASWLSPWLPLNLGHDLSLIVDEFGTKLFEEIDYINEGHNAERFATYFADDPSVKVPSIYW
HYTTTNVLTLEWIDGLKLLDTKQIQGAGLNTDTLITAGVTSGLRQLLEFGFFHADPHPGNLFALTDGRMAYIDFGMMDQL
EQDIKETLVDSVIHLINKDYQELAKDFVKLGFLAPDADIQPIIPALEMVLGNIMGEKVKDFNFKTITDKFSELMYEYPFR
VPAKFALIIRSLVTEEGLALSLNPNFKIVDVAYPYVARRLLKGESPGLRRRLIEVLFKDGKFQWQRLENLIGIARTDQNF
DILPTAQLGLQYLLSEEGEFLRKQLILAIIEDDRIHTEEVSRLWDLIQDDLQPSRLFNFALGALAEFSTQRAAAILPSVM
ATTNSQAKN
>Mature_568_residues
GQNHLSSTRRYDPEAIAKYYYYRLWLVMWRFLVIFFSFTSFVLGILWDKWRYKKVEDTPERATQLRKILTNLGPTFIKVG
QALSTRPDLIRKDFLEELTKLQDQLPAFDNQIAISIIETELGQNINDIYREVSPRPVAAASLGQVYKARLQSGESVAIKV
QRPNLLPIITLDLFLMRWGASWLSPWLPLNLGHDLSLIVDEFGTKLFEEIDYINEGHNAERFATYFADDPSVKVPSIYWH
YTTTNVLTLEWIDGLKLLDTKQIQGAGLNTDTLITAGVTSGLRQLLEFGFFHADPHPGNLFALTDGRMAYIDFGMMDQLE
QDIKETLVDSVIHLINKDYQELAKDFVKLGFLAPDADIQPIIPALEMVLGNIMGEKVKDFNFKTITDKFSELMYEYPFRV
PAKFALIIRSLVTEEGLALSLNPNFKIVDVAYPYVARRLLKGESPGLRRRLIEVLFKDGKFQWQRLENLIGIARTDQNFD
ILPTAQLGLQYLLSEEGEFLRKQLILAIIEDDRIHTEEVSRLWDLIQDDLQPSRLFNFALGALAEFSTQRAAAILPSVMA
TTNSQAKN

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=309, Percent_Identity=27.1844660194175, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI41393593, Length=445, Percent_Identity=24.9438202247191, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI217035081, Length=294, Percent_Identity=25.5102040816327, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI27363457, Length=303, Percent_Identity=27.3927392739274, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI217416386, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI34147522, Length=346, Percent_Identity=25.1445086705202, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI32261307, Length=316, Percent_Identity=22.1518987341772, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI2367309, Length=380, Percent_Identity=30, Blast_Score=183, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17559152, Length=295, Percent_Identity=30.8474576271186, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323282, Length=272, Percent_Identity=27.9411764705882, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=326, Percent_Identity=26.9938650306748, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325148, Length=256, Percent_Identity=30.46875, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24662575, Length=362, Percent_Identity=29.5580110497238, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI22024280, Length=240, Percent_Identity=32.5, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859849, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 65159; Mature: 65028

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQNHLSSTRRYDPEAIAKYYYYRLWLVMWRFLVIFFSFTSFVLGILWDKWRYKKVEDTP
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ERATQLRKILTNLGPTFIKVGQALSTRPDLIRKDFLEELTKLQDQLPAFDNQIAISIIET
HHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
ELGQNINDIYREVSPRPVAAASLGQVYKARLQSGESVAIKVQRPNLLPIITLDLFLMRWG
HHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHC
ASWLSPWLPLNLGHDLSLIVDEFGTKLFEEIDYINEGHNAERFATYFADDPSVKVPSIYW
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCCCEEEE
HYTTTNVLTLEWIDGLKLLDTKQIQGAGLNTDTLITAGVTSGLRQLLEFGFFHADPHPGN
EEECCCEEEEEECCCCHHHCCHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCC
LFALTDGRMAYIDFGMMDQLEQDIKETLVDSVIHLINKDYQELAKDFVKLGFLAPDADIQ
EEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
PIIPALEMVLGNIMGEKVKDFNFKTITDKFSELMYEYPFRVPAKFALIIRSLVTEEGLAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEE
SLNPNFKIVDVAYPYVARRLLKGESPGLRRRLIEVLFKDGKFQWQRLENLIGIARTDQNF
EECCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DILPTAQLGLQYLLSEEGEFLRKQLILAIIEDDRIHTEEVSRLWDLIQDDLQPSRLFNFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
LGALAEFSTQRAAAILPSVMATTNSQAKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GQNHLSSTRRYDPEAIAKYYYYRLWLVMWRFLVIFFSFTSFVLGILWDKWRYKKVEDTP
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ERATQLRKILTNLGPTFIKVGQALSTRPDLIRKDFLEELTKLQDQLPAFDNQIAISIIET
HHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
ELGQNINDIYREVSPRPVAAASLGQVYKARLQSGESVAIKVQRPNLLPIITLDLFLMRWG
HHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHC
ASWLSPWLPLNLGHDLSLIVDEFGTKLFEEIDYINEGHNAERFATYFADDPSVKVPSIYW
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEECCCCCCCCCEEEE
HYTTTNVLTLEWIDGLKLLDTKQIQGAGLNTDTLITAGVTSGLRQLLEFGFFHADPHPGN
EEECCCEEEEEECCCCHHHCCHHCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCC
LFALTDGRMAYIDFGMMDQLEQDIKETLVDSVIHLINKDYQELAKDFVKLGFLAPDADIQ
EEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
PIIPALEMVLGNIMGEKVKDFNFKTITDKFSELMYEYPFRVPAKFALIIRSLVTEEGLAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEE
SLNPNFKIVDVAYPYVARRLLKGESPGLRRRLIEVLFKDGKFQWQRLENLIGIARTDQNF
EECCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DILPTAQLGLQYLLSEEGEFLRKQLILAIIEDDRIHTEEVSRLWDLIQDDLQPSRLFNFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHH
LGALAEFSTQRAAAILPSVMATTNSQAKN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]