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The map label for this gene is aspS

Identifier: 113475986

GI number: 113475986

Start: 3638104

End: 3639891

Strand: Direct

Name: aspS

Synonym: Tery_2354

Alternate gene names: 113475986

Gene position: 3638104-3639891 (Clockwise)

Preceding gene: 113475979

Following gene: 113475990

Centisome position: 46.94

GC content: 42.11

Gene sequence:

>1788_bases
ATGCGAACCCATTATTGTGGCCAAGTAAATAGTAATAATATTGAAGAAACTGTGAACCTCTGTGGATGGGTAGACCGCCG
TCGGGATCATGGGGGGGTAATTTTTTTAGACTTGCGCGATCGCTCTGGTCTTATCCAAATTGTCAGCGACCCAGAGCGCA
CACCAGACTCCTATCAAATAGCAGGAGATATTCGTAATGAATATGTTGTACAGATCACAGGTCGAGTCAGTCGTCGCCCC
GAAGAGTCTCTCAACCCCAAACTTCCTACTGGGGAAATCGAAATTTACGCCGATGATATTCAACTATTGAATGGCTTAGG
TAAACAACTGCCATTTCAGGTTTCCACAGCTGAAACAGAAGCAGTACGAGAAGAGTTGCGACTAAAATACCGATATTTAG
ACTTGAGAAGGGAACGCATGACTCGCAACTTATTATTACGTCATGAAGTTATCAAAGCGATACGTCGTTTTCTGGAAGAC
GAACAAAATTTTGTTGAAATTGAAACCCCGATCCTAACACGCTCTACTCCAGAAGGAGCAAGGGATTATCTAGTTCCCAG
TCGCGTTCATCCTGGGGAATGGTTTGCCTTACCCCAATCTCCCCAACTTTTTAAGCAAATATTGATGGTGTCTGGTTTTG
ACCGTTATTATCAAATCGCCCGTTGTTTCCGGGATGAAGATTTGCGAGCGGATAGACAACCAGAATTTACTCAGTTAGAT
ATGGAAATGAGCTTCATGTCTCAGGAGGAAATTCTGCAGTTAAATGAGAAGTTGGTAGCTTACATTTTTCAGAAAGTAAA
AGGTATAGACTTACCTTTACCATTTCCGCGACTGACTTATACCGAAGCGATGGAACGTTATGGTAGTGATAAACCTGATG
TTCGCTTCGGTTTAGAATTAGTGGATGTCTCTGACTTGATGAAAGATTCTGGTTTTAAGGTATTTTCCGGTGCCATTGCT
AAAGGTGGGATCGTGAAAGTATTGCCTATTCCTGGAGGTAACGATGCCATCTCCAATGTTAGAATTAAACCTGGTGGAGA
CTTGTTTAAAGAAGCGAGTGAAGTAGGAGCAAAAGGTTTAGCTTACGTTCGTGTCAAAGAAGGCGGTAAGATAGATACTA
TTGGAGCTATCAAAGACAACCTCACCGATGAGCAAAAACAGGAATTACTCAAACGTACTAATGCTCAACCTGGTCATTTG
CTGTTATTTGCCGCGGATGACGCAAATACTGTTAATAAAACCTTAGACCGCCTCCGGTTGGTTATCGGGGAACAATTAGG
ATTAATTGATCAGGATAAAATTAGTCTATTATGGGTGACAGACTTTCCCATGTTTGAATGGAATGAGGATGAACAACGTT
TGGAAGCTTTACACCACCCCTTTACTGCACCTCACCCAGACGATATTAATGACCTCAAGACTGCACGAGCCCAAGCTTAT
GATTTAGTGTTTAATGGTTATGAAGTTGGCGGTGGTAGTCTGCGGATATATCAACGGGATGTTCAGGAAAAGGTATTTGA
AGCTATCGGTTTATCTGCTCAGGAAGCTGATAATAAGTTTGGCTTTTTATTGGAAGCATTTGAATATGGTACTCCTCCCC
ACGGTGGTATTGCTTATGGTTTAGATCGGTTAGTGATGCTGTTAGCAGTCGAGGAGTCTATTCGGGATGTAATTGCATTT
CCGAAGACTCAACAGGCAAAGTGTTTGTTGGCAAATGCACCCTCTGAGGTTGATAAAAAGCAGTTGAAAGAATTACACGT
TAGTTCTATTTCTAAGGCGAAATCTTAG

Upstream 100 bases:

>100_bases
GTTAAAAATAAAGATTTATCCTAGAAACCGGGCCTCCGCCTGGGTAAGTCTTAATAATGATATTATGTATTGTTTAGCTA
AATTTGTAATTTAGACAATT

Downstream 100 bases:

>100_bases
CCAGACTTACAGTACAAGGAGCAGGAAACCCACCCCCTTGCTGAACAAGTCTTTTTCAAGAATAGTAGAGGCCTTGCATG
CAATGTCCCTACGGAGAAAA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQIAGDIRNEYVVQITGRVSRRP
EESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETEAVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLED
EQNFVEIETPILTRSTPEGARDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLD
MEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLELVDVSDLMKDSGFKVFSGAIA
KGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGLAYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHL
LLFAADDANTVNKTLDRLRLVIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAY
DLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAVEESIRDVIAF
PKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS

Sequences:

>Translated_595_residues
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQIAGDIRNEYVVQITGRVSRRP
EESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETEAVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLED
EQNFVEIETPILTRSTPEGARDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLD
MEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLELVDVSDLMKDSGFKVFSGAIA
KGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGLAYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHL
LLFAADDANTVNKTLDRLRLVIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAY
DLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAVEESIRDVIAF
PKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS
>Mature_595_residues
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQIAGDIRNEYVVQITGRVSRRP
EESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETEAVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLED
EQNFVEIETPILTRSTPEGARDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLD
MEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLELVDVSDLMKDSGFKVFSGAIA
KGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGLAYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHL
LLFAADDANTVNKTLDRLRLVIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAY
DLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAVEESIRDVIAF
PKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=603, Percent_Identity=41.2935323383085, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI5031815, Length=299, Percent_Identity=27.4247491638796, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI194272210, Length=299, Percent_Identity=27.4247491638796, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI45439306, Length=247, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788173, Length=602, Percent_Identity=49.8338870431894, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1790571, Length=297, Percent_Identity=26.9360269360269, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789256, Length=288, Percent_Identity=27.4305555555556, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI32566633, Length=616, Percent_Identity=34.9025974025974, Blast_Score=334, Evalue=7e-92,
Organism=Caenorhabditis elegans, GI71994340, Length=304, Percent_Identity=26.3157894736842, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17535925, Length=304, Percent_Identity=26.3157894736842, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535927, Length=315, Percent_Identity=26.031746031746, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17551876, Length=279, Percent_Identity=24.3727598566308, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=633, Percent_Identity=33.175355450237, Blast_Score=266, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6320242, Length=262, Percent_Identity=27.4809160305344, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321807, Length=289, Percent_Identity=27.3356401384083, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324256, Length=189, Percent_Identity=28.042328042328, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=260, Percent_Identity=30, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584738, Length=606, Percent_Identity=40.2640264026403, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24640849, Length=297, Percent_Identity=24.9158249158249, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640851, Length=297, Percent_Identity=24.9158249158249, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_TRIEI (Q112K0)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_722047.1
- ProteinModelPortal:   Q112K0
- SMR:   Q112K0
- STRING:   Q112K0
- GeneID:   4245002
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2354
- NMPDR:   fig|203124.1.peg.4632
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   Q112K0
- ProtClustDB:   PRK00476
- BioCyc:   TERY203124:TERY_2354-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 67500; Mature: 67500

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEE
AGDIRNEYVVQITGRVSRRPEESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETE
EECCCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEEHHHHHHHHCCHHCCEEEECHHHH
AVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLEDEQNFVEIETPILTRSTPEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCC
RDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLD
HHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEC
MEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLEL
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEECEEE
VDVSDLMKDSGFKVFSGAIAKGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGL
ECHHHHHHCCCCEEEECHHCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHCCCCE
AYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHLLLFAADDANTVNKTLDRLRL
EEEEEECCCCEEEECCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
VIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAY
HHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYG
HEEEECEEECCCEEEEHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHH
LDRLVMLLAVEESIRDVIAFPKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCEEE
AGDIRNEYVVQITGRVSRRPEESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETE
EECCCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEEHHHHHHHHCCHHCCEEEECHHHH
AVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLEDEQNFVEIETPILTRSTPEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCCCC
RDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLD
HHCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEC
MEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLEL
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEECEEE
VDVSDLMKDSGFKVFSGAIAKGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGL
ECHHHHHHCCCCEEEECHHCCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHHHCCCCE
AYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHLLLFAADDANTVNKTLDRLRL
EEEEEECCCCEEEECCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
VIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAY
HHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
DLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYG
HEEEECEEECCCEEEEHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHH
LDRLVMLLAVEESIRDVIAFPKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA