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The map label for this gene is rnc [H]

Identifier: 113475790

GI number: 113475790

Start: 3348503

End: 3349204

Strand: Direct

Name: rnc [H]

Synonym: Tery_2144

Alternate gene names: 113475790

Gene position: 3348503-3349204 (Clockwise)

Preceding gene: 113475787

Following gene: 113475791

Centisome position: 43.21

GC content: 33.62

Gene sequence:

>702_bases
ATGATAGATAAAATACCTGAGTTTAAAAATCAAAAACTTCTTCAACAAGCTCTAACCCATCGTTCCTATTTAAACGAAAA
TTATGGAGATGAGGAAGACAACGAAAGTCTAGAATTTATCGGCGATGCTTTACTAGGTTTCTTAGTAGGAGAATTGCTAT
ATAGAAGATACAAAGAAGAGCATAATCTCAAACCCAAAGAACTTACTCGGATCCGTTCACTTTTAGTAGATGAAAAACAA
TTAGCAAAGTTCGCAGTTCAATTGGGAATTGGTGCAAAAATGCGCTTAGGTAAAGGTGCGGAAAAAGATGGTGGAAGGAA
AAATCCAGCTTTACTAAGTGACACTTTTGAAGCAATAATTGGAGCCTATTTTTTGGACTCAAATTTAACGAAAGTTAAAC
CTTTTATTAAAAGGCTTTTTGAACCTGTTGCAGATAATATAATTTTGCCTAATTATGGTGATAATTCACAACCAAAAGAT
TTAGTAGATACTAAGGGTAAATTTCAACAGTGGGCACTCGCAAAATTTGGAGAAAATCCTAGATATGAATCTAATAATGG
AGAAGGTTTAGATCATGCTAAAATATTTACTGCGGAAGTTAGAGTTAGAGGAAAATTATATGGTGTTGGTAAAGGAAATC
GTAAACAAGAAGCAGAAAAAAGTGCGGCAGAAAAAGCTCTGAAAAAAGTAGGGTTAATTTGA

Upstream 100 bases:

>100_bases
GGCTCATTCTTCCTTTTAGCTGATAGCTGATAGTTGATAGCTGAATACTTACCCAATATAGATAAATATAAATAAATATC
AATAAATTGAAAATTAGCAA

Downstream 100 bases:

>100_bases
TTGAATAAGGAAAAACTAATTTGGATAATTTCCTAGATTCATTTTTTTGAAGAGCTTAATTTTTTATTTGGGCAAGTCAG
CCAATAAATTTTTATTTAAA

Product: RNAse III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MIDKIPEFKNQKLLQQALTHRSYLNENYGDEEDNESLEFIGDALLGFLVGELLYRRYKEEHNLKPKELTRIRSLLVDEKQ
LAKFAVQLGIGAKMRLGKGAEKDGGRKNPALLSDTFEAIIGAYFLDSNLTKVKPFIKRLFEPVADNIILPNYGDNSQPKD
LVDTKGKFQQWALAKFGENPRYESNNGEGLDHAKIFTAEVRVRGKLYGVGKGNRKQEAEKSAAEKALKKVGLI

Sequences:

>Translated_233_residues
MIDKIPEFKNQKLLQQALTHRSYLNENYGDEEDNESLEFIGDALLGFLVGELLYRRYKEEHNLKPKELTRIRSLLVDEKQ
LAKFAVQLGIGAKMRLGKGAEKDGGRKNPALLSDTFEAIIGAYFLDSNLTKVKPFIKRLFEPVADNIILPNYGDNSQPKD
LVDTKGKFQQWALAKFGENPRYESNNGEGLDHAKIFTAEVRVRGKLYGVGKGNRKQEAEKSAAEKALKKVGLI
>Mature_233_residues
MIDKIPEFKNQKLLQQALTHRSYLNENYGDEEDNESLEFIGDALLGFLVGELLYRRYKEEHNLKPKELTRIRSLLVDEKQ
LAKFAVQLGIGAKMRLGKGAEKDGGRKNPALLSDTFEAIIGAYFLDSNLTKVKPFIKRLFEPVADNIILPNYGDNSQPKD
LVDTKGKFQQWALAKFGENPRYESNNGEGLDHAKIFTAEVRVRGKLYGVGKGNRKQEAEKSAAEKALKKVGLI

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030234, Length=231, Percent_Identity=29.8701298701299, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI155030236, Length=231, Percent_Identity=29.8701298701299, Blast_Score=81, Evalue=8e-16,
Organism=Escherichia coli, GI1788920, Length=211, Percent_Identity=33.175355450237, Blast_Score=107, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17506883, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202651, Length=232, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137682, Length=228, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 26284; Mature: 26284

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50137 DS_RBD ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKIPEFKNQKLLQQALTHRSYLNENYGDEEDNESLEFIGDALLGFLVGELLYRRYKEE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HNLKPKELTRIRSLLVDEKQLAKFAVQLGIGAKMRLGKGAEKDGGRKNPALLSDTFEAII
HCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GAYFLDSNLTKVKPFIKRLFEPVADNIILPNYGDNSQPKDLVDTKGKFQQWALAKFGENP
HHHHHCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCC
RYESNNGEGLDHAKIFTAEVRVRGKLYGVGKGNRKQEAEKSAAEKALKKVGLI
CCCCCCCCCCCHHHEEHHHEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDKIPEFKNQKLLQQALTHRSYLNENYGDEEDNESLEFIGDALLGFLVGELLYRRYKEE
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HNLKPKELTRIRSLLVDEKQLAKFAVQLGIGAKMRLGKGAEKDGGRKNPALLSDTFEAII
HCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GAYFLDSNLTKVKPFIKRLFEPVADNIILPNYGDNSQPKDLVDTKGKFQQWALAKFGENP
HHHHHCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCC
RYESNNGEGLDHAKIFTAEVRVRGKLYGVGKGNRKQEAEKSAAEKALKKVGLI
CCCCCCCCCCCHHHEEHHHEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]