Click here to switch to the map view.

The map label for this gene is mrdA [H]

Identifier: 113475742

GI number: 113475742

Start: 3260681

End: 3262474

Strand: Direct

Name: mrdA [H]

Synonym: Tery_2090

Alternate gene names: 113475742

Gene position: 3260681-3262474 (Clockwise)

Preceding gene: 113475741

Following gene: 113475744

Centisome position: 42.07

GC content: 40.25

Gene sequence:

>1794_bases
ATGACTCAAGATTTTGGTTTATGTTCTAAATTTCCCTACCTGGCTAGAAGTACTGTAGAGGAAGGTATATCAAAACGTCA
TCGCTTAGGACAAGCACTCATAATGATGTTATTGATTACCAGCTTTATTAGTATCCATGCTTATCGTATAGTACAATTAC
AATTAGTTCAAGGAGAATATAACCGGGAACGTGCAGACAACAACCGTGTTCGCTTAACACCAGTACCATCAAGTCGTGGC
ACTATCTACGATCGCAAAGGTAAAGTATTAGCAGGTAACTTCCTTTCTCGCTCTGTATATTTATGGCCAAGCGAATACTC
ACCTGCAAAATGGTTGGAGGTAGCAACGGAGCTTAGTCTAATCTTAGATATTCCAGTGGCTGATATTATTAACAAGTTAA
ATAAAGCTGGCTATAAATCAGCCTTACCCGTCAGAATTACCTCAAACATGGACCGCACTACTTTTGTCGCATTAGCAGAA
AAAGTAGGTGAGACAAGAGGAATAGAGATTCGTACTGAAAATACTCGTTACTATCCTCATGGCACTCTAGCAGCTCATTT
ATTAGGATATACTGGTGAAGCAACCAAAGAAGAATTAATCGCTAACCCCAAATATCCAATGGGAATGATCGTGGGAAAAA
TGGGAATCGAATATTCAGCAAATTCAAAACTAGAAGGAGTTTGGGGTAATCGTTTAATTGAAGTTGACGCCAAAGGTAAT
GAAATTCAAGAGTTAGGAATAGAAAATCCGATTCCAGGCAAACCAGTAAAATTAACCATTGATTTTGATATCCAAAAAAC
TGCAGAAAAAGCGTTAGGAAATCGCCGGGGTGCCGTAGTTGCAATTAATCCTAAAACAGGAGAAGTCTTAGCAATGGCAA
GCGGACCCACATTTAACCCCAGTATATTTGCAGGCCAAGTGACCAGGGAAAAATGGCAACATCTTCAAGGTGCAAGCAAG
CCTTTTTTGAATCGCGCTCTTCAGGGTTATCCTCCAGGAAGCACTTTCAAAGCTGTTACTTCTGTTGCGGCCCTACAGTC
TGGCAAATATTCTCCTAACTCCAAAGTTGGAACTTACAATGCTGTAACTATTGGTGGTATAACTTTTAATGAACATAGTG
GTGGTTATGGATTAATTGGCTTTCGGGATGCTTTAGCTTACAGTAGTAATACATTTTACTATCAAGTAGGTGTAAAAACA
GGCCCGGAACAAATTTCTAAGTGGGGGCGAGAGTTAGGTATTGGTGGCAGTATTGACTTCAAACTATTCGGACTCAATGG
TAGTCATGGTCAAATCCCTACTCCCAAGGAAAAAGAAAAAATATATGGGGAACCTTGGCATATTGCTGATATTGTGACGA
TGGGAATAGGTCAGGGTTTGGTATTGGTAACACCTTTAGAATCTTCAGTTATGGTAAGTACGATCGCTAATGGTGGGTAT
CGAGTGCAACCTCATTTATTTGCTTCTGACACTAATACTGATACTACTAAACCAATTAGTACCGGACTAAAACCTTCAAC
TCTTAAAACAGTGCGAGAAGGATTAATTGATGTAGTTAGGAAGGGTACTGCTCGTCGGTTGAATGATGGTACTATTCCAT
TATCCGGGGGTAAAACTGGTACAGTGGAACTTCCAGGGCAAGCTGATAACGCAATGTATATAGGTTTTGCACCTGCCTAT
AATCCTGAAATTGCTGTAGCGATTGCAGTTGAAGGCGGTGGTTACGGTTCGGTAGGAGCTGCTCCCATTGCCAAAGCAAT
TTTTGATACCTATTTTGGTAATCAAGGAAAATAA

Upstream 100 bases:

>100_bases
TTTCTGTAGATCCCAAGATATACAGATAAAAAGTGGTTAATCTTCCGGAATATCAGCAAGGATCAAAGAAAAATCAAGAT
AAAACACTTATGAAATAACA

Downstream 100 bases:

>100_bases
TTAATCAATAAAATATTTATGTCATGTTTAGTATAGTTTATGTAATAGGTCGTAGGTTTTAAAGAGAGTAGGATAAGGTA
AAAAGCTATCAAGCTTACCT

Product: peptidoglycan glycosyltransferase

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MTQDFGLCSKFPYLARSTVEEGISKRHRLGQALIMMLLITSFISIHAYRIVQLQLVQGEYNRERADNNRVRLTPVPSSRG
TIYDRKGKVLAGNFLSRSVYLWPSEYSPAKWLEVATELSLILDIPVADIINKLNKAGYKSALPVRITSNMDRTTFVALAE
KVGETRGIEIRTENTRYYPHGTLAAHLLGYTGEATKEELIANPKYPMGMIVGKMGIEYSANSKLEGVWGNRLIEVDAKGN
EIQELGIENPIPGKPVKLTIDFDIQKTAEKALGNRRGAVVAINPKTGEVLAMASGPTFNPSIFAGQVTREKWQHLQGASK
PFLNRALQGYPPGSTFKAVTSVAALQSGKYSPNSKVGTYNAVTIGGITFNEHSGGYGLIGFRDALAYSSNTFYYQVGVKT
GPEQISKWGRELGIGGSIDFKLFGLNGSHGQIPTPKEKEKIYGEPWHIADIVTMGIGQGLVLVTPLESSVMVSTIANGGY
RVQPHLFASDTNTDTTKPISTGLKPSTLKTVREGLIDVVRKGTARRLNDGTIPLSGGKTGTVELPGQADNAMYIGFAPAY
NPEIAVAIAVEGGGYGSVGAAPIAKAIFDTYFGNQGK

Sequences:

>Translated_597_residues
MTQDFGLCSKFPYLARSTVEEGISKRHRLGQALIMMLLITSFISIHAYRIVQLQLVQGEYNRERADNNRVRLTPVPSSRG
TIYDRKGKVLAGNFLSRSVYLWPSEYSPAKWLEVATELSLILDIPVADIINKLNKAGYKSALPVRITSNMDRTTFVALAE
KVGETRGIEIRTENTRYYPHGTLAAHLLGYTGEATKEELIANPKYPMGMIVGKMGIEYSANSKLEGVWGNRLIEVDAKGN
EIQELGIENPIPGKPVKLTIDFDIQKTAEKALGNRRGAVVAINPKTGEVLAMASGPTFNPSIFAGQVTREKWQHLQGASK
PFLNRALQGYPPGSTFKAVTSVAALQSGKYSPNSKVGTYNAVTIGGITFNEHSGGYGLIGFRDALAYSSNTFYYQVGVKT
GPEQISKWGRELGIGGSIDFKLFGLNGSHGQIPTPKEKEKIYGEPWHIADIVTMGIGQGLVLVTPLESSVMVSTIANGGY
RVQPHLFASDTNTDTTKPISTGLKPSTLKTVREGLIDVVRKGTARRLNDGTIPLSGGKTGTVELPGQADNAMYIGFAPAY
NPEIAVAIAVEGGGYGSVGAAPIAKAIFDTYFGNQGK
>Mature_596_residues
TQDFGLCSKFPYLARSTVEEGISKRHRLGQALIMMLLITSFISIHAYRIVQLQLVQGEYNRERADNNRVRLTPVPSSRGT
IYDRKGKVLAGNFLSRSVYLWPSEYSPAKWLEVATELSLILDIPVADIINKLNKAGYKSALPVRITSNMDRTTFVALAEK
VGETRGIEIRTENTRYYPHGTLAAHLLGYTGEATKEELIANPKYPMGMIVGKMGIEYSANSKLEGVWGNRLIEVDAKGNE
IQELGIENPIPGKPVKLTIDFDIQKTAEKALGNRRGAVVAINPKTGEVLAMASGPTFNPSIFAGQVTREKWQHLQGASKP
FLNRALQGYPPGSTFKAVTSVAALQSGKYSPNSKVGTYNAVTIGGITFNEHSGGYGLIGFRDALAYSSNTFYYQVGVKTG
PEQISKWGRELGIGGSIDFKLFGLNGSHGQIPTPKEKEKIYGEPWHIADIVTMGIGQGLVLVTPLESSVMVSTIANGGYR
VQPHLFASDTNTDTTKPISTGLKPSTLKTVREGLIDVVRKGTARRLNDGTIPLSGGKTGTVELPGQADNAMYIGFAPAYN
PEIAVAIAVEGGGYGSVGAAPIAKAIFDTYFGNQGK

Specific function: Cell wall formation; PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross- linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=597, Percent_Identity=27.6381909547739, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1786272, Length=578, Percent_Identity=25.6055363321799, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR017790 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 64542; Mature: 64410

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDFGLCSKFPYLARSTVEEGISKRHRLGQALIMMLLITSFISIHAYRIVQLQLVQGEY
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCC
NRERADNNRVRLTPVPSSRGTIYDRKGKVLAGNFLSRSVYLWPSEYSPAKWLEVATELSL
CCCCCCCCCEEEEECCCCCCCEEECCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHEE
ILDIPVADIINKLNKAGYKSALPVRITSNMDRTTFVALAEKVGETRGIEIRTENTRYYPH
EEECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCEECCC
GTLAAHLLGYTGEATKEELIANPKYPMGMIVGKMGIEYSANSKLEGVWGNRLIEVDAKGN
HHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCEECCCCCCCEECCCEEEEEECCCC
EIQELGIENPIPGKPVKLTIDFDIQKTAEKALGNRRGAVVAINPKTGEVLAMASGPTFNP
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCC
SIFAGQVTREKWQHLQGASKPFLNRALQGYPPGSTFKAVTSVAALQSGKYSPNSKVGTYN
CEEECHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
AVTIGGITFNEHSGGYGLIGFRDALAYSSNTFYYQVGVKTGPEQISKWGRELGIGGSIDF
EEEEEEEEEECCCCCEEEEEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEE
KLFGLNGSHGQIPTPKEKEKIYGEPWHIADIVTMGIGQGLVLVTPLESSVMVSTIANGGY
EEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCE
RVQPHLFASDTNTDTTKPISTGLKPSTLKTVREGLIDVVRKGTARRLNDGTIPLSGGKTG
EECCEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEE
TVELPGQADNAMYIGFAPAYNPEIAVAIAVEGGGYGSVGAAPIAKAIFDTYFGNQGK
EEECCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TQDFGLCSKFPYLARSTVEEGISKRHRLGQALIMMLLITSFISIHAYRIVQLQLVQGEY
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCC
NRERADNNRVRLTPVPSSRGTIYDRKGKVLAGNFLSRSVYLWPSEYSPAKWLEVATELSL
CCCCCCCCCEEEEECCCCCCCEEECCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHEE
ILDIPVADIINKLNKAGYKSALPVRITSNMDRTTFVALAEKVGETRGIEIRTENTRYYPH
EEECCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCEECCC
GTLAAHLLGYTGEATKEELIANPKYPMGMIVGKMGIEYSANSKLEGVWGNRLIEVDAKGN
HHHHHHHHCCCCCCCHHHHHCCCCCCCEEEEECCCCEECCCCCCCEECCCEEEEEECCCC
EIQELGIENPIPGKPVKLTIDFDIQKTAEKALGNRRGAVVAINPKTGEVLAMASGPTFNP
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCC
SIFAGQVTREKWQHLQGASKPFLNRALQGYPPGSTFKAVTSVAALQSGKYSPNSKVGTYN
CEEECHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
AVTIGGITFNEHSGGYGLIGFRDALAYSSNTFYYQVGVKTGPEQISKWGRELGIGGSIDF
EEEEEEEEEECCCCCEEEEEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEE
KLFGLNGSHGQIPTPKEKEKIYGEPWHIADIVTMGIGQGLVLVTPLESSVMVSTIANGGY
EEEECCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCE
RVQPHLFASDTNTDTTKPISTGLKPSTLKTVREGLIDVVRKGTARRLNDGTIPLSGGKTG
EECCEEEECCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEE
TVELPGQADNAMYIGFAPAYNPEIAVAIAVEGGGYGSVGAAPIAKAIFDTYFGNQGK
EEECCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]