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The map label for this gene is gatA

Identifier: 113475718

GI number: 113475718

Start: 3226722

End: 3228179

Strand: Direct

Name: gatA

Synonym: Tery_2065

Alternate gene names: 113475718

Gene position: 3226722-3228179 (Clockwise)

Preceding gene: 113475717

Following gene: 113475719

Centisome position: 41.63

GC content: 40.05

Gene sequence:

>1458_bases
ATGGCATCCATTAGCGATATCCATCAACAATTAATCAGTAAGCAACGCTCTGCTGTAGAAATTACCCAAGAAGCTCTCGA
AAATATCAACCAATTGGAGCCGAAGTTAAAAAGCTTTATCTGTGTTACAGCAGAAAAGGCCATTGCTCAGGCCCGTCAGG
TGGATGCAAAGATTGCTGCAGGAGAGAAAATTGGACTACTAACAGGGATTCCGATCGCTGTAAAGGATAATATATGTACT
AGGGGTATCCCTACTACTTGTGGGTCTAAGATTTTACAAAACTTTATTCCCCCTTATGAATCTACGGTAACTCAAAAACT
TGTGGATGCTGGGGCAATAATTTTAGGCAAGACCAATTTAGATGAATTTGGTATGGGCAGTTCAACAGAAAATTCTGCCT
ATCAAGTCACGACTAACCCGTGGGATAACACTCGAGTTCCTGGTGGATCTTCGGGAGGGTCAGCAGCAGCAGTAGCATCG
GCAGAATCTGTAGTAGCATTGGGTTCAGATACAGGTGGGTCGATTCGTCAACCAGCATCTTTTTGTGGAGTGGTAGGAAT
TAAGCCTACTTATGGTCTGGTTTCTCGCTATGGGTTAGTGGCTTATGCTTCTTCTATGGATCAAATAGGGCCGTTGAGTA
GAACTGTGAAAGATTCTGCTATTTTATTGCAGGCGATCGCTGGTTATGACCCTAAAGATTCTACTAGTCTTAATGTCCCT
GTCCCAGATTACACTAAAAACCTCACACCTAATTTAAGACCTAAAGGGCAAATTAGAATTGGTCTCATTCAAGAGACTTT
TGGTGATGGTTTAGACTCATCTGTTCTTCAAGCTTTTACTAAGGCAGTGGAACTAATGCAGGAGTTGGGGGCAGAAATTC
AGGTAATTTCTTGTCCTAGATTTAGTTACGGTTTACCTACTTATTATGTTATTGCTCCATCGGAGGCTTCGGCAAATTTA
GCCCGCTATGATGGGGTCAAATATGGTTTCCGTGCTAGTGAGTCGGAAAACCTCTTGAATATGTATGCTAAGACTCGTTC
TGAAGGTTTTGGTTCAGAAGTTAAACGCCGAATTATGATTGGTACTTATGCTTTATCGGCTGGATATTATGATGCTTATT
ATCTGAAAGCTCAAAAAGTTCGGACTTTAATTAAGGAAGATTTTGATAAAGCTTTTGCTAAAGTAGATATTTTGGCTTGC
CCCACTTCTCCAACTACAGCATTTAAGCTGGGTGAAAAAAGTGATAATCCACTGAGTATGTATTTGTCTGACTTAATGAC
TATTCCAGTTAATTTGGCTGGTTTACCTGCTTTGAGTTTACCCTGTGGCTTTGATCAACAAGGGTTGCCTATTGGTATGC
AATTGATAAGTAATGTTTTGAAAGAAGATTTACTATTTGAAGCAGCTTATGTTTATGAACAAGCTAATAATTGGTATAAA
TTCCAACCTCAGCTTTAA

Upstream 100 bases:

>100_bases
TAAGGGAAACCCTGAGAAGCAAGCACCTCTCGTTGTCTATACTTTTAACAGTGAGAGTGCCAAAATCTAATAGTTGAATT
TTAGGAATGACAGTATAGGC

Downstream 100 bases:

>100_bases
AAATTTAGTTTTGAGTTTTGAGTTTTTATTGATTAGGTTTGAAGTGTTCATAATAGTGTGTTAGTTAATAGCTGCAATTG
GAGCTTAGGAGTTAGGCACA

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MASISDIHQQLISKQRSAVEITQEALENINQLEPKLKSFICVTAEKAIAQARQVDAKIAAGEKIGLLTGIPIAVKDNICT
RGIPTTCGSKILQNFIPPYESTVTQKLVDAGAIILGKTNLDEFGMGSSTENSAYQVTTNPWDNTRVPGGSSGGSAAAVAS
AESVVALGSDTGGSIRQPASFCGVVGIKPTYGLVSRYGLVAYASSMDQIGPLSRTVKDSAILLQAIAGYDPKDSTSLNVP
VPDYTKNLTPNLRPKGQIRIGLIQETFGDGLDSSVLQAFTKAVELMQELGAEIQVISCPRFSYGLPTYYVIAPSEASANL
ARYDGVKYGFRASESENLLNMYAKTRSEGFGSEVKRRIMIGTYALSAGYYDAYYLKAQKVRTLIKEDFDKAFAKVDILAC
PTSPTTAFKLGEKSDNPLSMYLSDLMTIPVNLAGLPALSLPCGFDQQGLPIGMQLISNVLKEDLLFEAAYVYEQANNWYK
FQPQL

Sequences:

>Translated_485_residues
MASISDIHQQLISKQRSAVEITQEALENINQLEPKLKSFICVTAEKAIAQARQVDAKIAAGEKIGLLTGIPIAVKDNICT
RGIPTTCGSKILQNFIPPYESTVTQKLVDAGAIILGKTNLDEFGMGSSTENSAYQVTTNPWDNTRVPGGSSGGSAAAVAS
AESVVALGSDTGGSIRQPASFCGVVGIKPTYGLVSRYGLVAYASSMDQIGPLSRTVKDSAILLQAIAGYDPKDSTSLNVP
VPDYTKNLTPNLRPKGQIRIGLIQETFGDGLDSSVLQAFTKAVELMQELGAEIQVISCPRFSYGLPTYYVIAPSEASANL
ARYDGVKYGFRASESENLLNMYAKTRSEGFGSEVKRRIMIGTYALSAGYYDAYYLKAQKVRTLIKEDFDKAFAKVDILAC
PTSPTTAFKLGEKSDNPLSMYLSDLMTIPVNLAGLPALSLPCGFDQQGLPIGMQLISNVLKEDLLFEAAYVYEQANNWYK
FQPQL
>Mature_484_residues
ASISDIHQQLISKQRSAVEITQEALENINQLEPKLKSFICVTAEKAIAQARQVDAKIAAGEKIGLLTGIPIAVKDNICTR
GIPTTCGSKILQNFIPPYESTVTQKLVDAGAIILGKTNLDEFGMGSSTENSAYQVTTNPWDNTRVPGGSSGGSAAAVASA
ESVVALGSDTGGSIRQPASFCGVVGIKPTYGLVSRYGLVAYASSMDQIGPLSRTVKDSAILLQAIAGYDPKDSTSLNVPV
PDYTKNLTPNLRPKGQIRIGLIQETFGDGLDSSVLQAFTKAVELMQELGAEIQVISCPRFSYGLPTYYVIAPSEASANLA
RYDGVKYGFRASESENLLNMYAKTRSEGFGSEVKRRIMIGTYALSAGYYDAYYLKAQKVRTLIKEDFDKAFAKVDILACP
TSPTTAFKLGEKSDNPLSMYLSDLMTIPVNLAGLPALSLPCGFDQQGLPIGMQLISNVLKEDLLFEAAYVYEQANNWYKF
QPQL

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family

Homologues:

Organism=Homo sapiens, GI222831590, Length=495, Percent_Identity=39.7979797979798, Blast_Score=344, Evalue=9e-95,
Organism=Homo sapiens, GI195972892, Length=500, Percent_Identity=26.2, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI166795287, Length=181, Percent_Identity=32.5966850828729, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=415, Percent_Identity=38.0722891566265, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17537465, Length=493, Percent_Identity=27.3833671399594, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17556264, Length=203, Percent_Identity=35.4679802955665, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990152, Length=245, Percent_Identity=31.0204081632653, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538252, Length=167, Percent_Identity=31.1377245508982, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556276, Length=197, Percent_Identity=35.0253807106599, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17556278, Length=197, Percent_Identity=35.0253807106599, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538254, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323950, Length=413, Percent_Identity=38.2566585956416, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6319685, Length=476, Percent_Identity=30.2521008403361, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6320448, Length=232, Percent_Identity=29.3103448275862, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648113, Length=478, Percent_Identity=41.8410041841004, Blast_Score=342, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24652985, Length=509, Percent_Identity=25.3438113948919, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19922090, Length=509, Percent_Identity=25.3438113948919, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24652981, Length=509, Percent_Identity=25.3438113948919, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24652983, Length=509, Percent_Identity=25.3438113948919, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24644968, Length=507, Percent_Identity=26.232741617357, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45550774, Length=496, Percent_Identity=24.1935483870968, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24648435, Length=496, Percent_Identity=24.1935483870968, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24648437, Length=496, Percent_Identity=24.1935483870968, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI161078093, Length=511, Percent_Identity=25.6360078277886, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24648441, Length=437, Percent_Identity=24.4851258581236, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24648439, Length=437, Percent_Identity=24.4851258581236, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356731, Length=235, Percent_Identity=29.3617021276596, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GATA_TRIEI (Q113L8)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721779.1
- ProteinModelPortal:   Q113L8
- SMR:   Q113L8
- STRING:   Q113L8
- GeneID:   4245713
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_2065
- NMPDR:   fig|203124.1.peg.2204
- eggNOG:   COG0154
- HOGENOM:   HBG481888
- OMA:   RWGLIAF
- PhylomeDB:   Q113L8
- ProtClustDB:   PRK00012
- BioCyc:   TERY203124:TERY_2065-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_00120
- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412
- Gene3D:   G3DSA:3.90.1300.10
- PANTHER:   PTHR11895
- TIGRFAMs:   TIGR00132

Pfam domain/function: PF01425 Amidase; SSF75304 Amidase_sig_enz

EC number: 6.3.5.-

Molecular weight: Translated: 52225; Mature: 52094

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00571 AMIDASES

Important sites: ACT_SITE 75-75 ACT_SITE 150-150 ACT_SITE 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASISDIHQQLISKQRSAVEITQEALENINQLEPKLKSFICVTAEKAIAQARQVDAKIAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEHHHHHHHHHHHHHHHHHHC
GEKIGLLTGIPIAVKDNICTRGIPTTCGSKILQNFIPPYESTVTQKLVDAGAIILGKTNL
CCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCC
DEFGMGSSTENSAYQVTTNPWDNTRVPGGSSGGSAAAVASAESVVALGSDTGGSIRQPAS
HHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCHH
FCGVVGIKPTYGLVSRYGLVAYASSMDQIGPLSRTVKDSAILLQAIAGYDPKDSTSLNVP
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
VPDYTKNLTPNLRPKGQIRIGLIQETFGDGLDSSVLQAFTKAVELMQELGAEIQVISCPR
CCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
FSYGLPTYYVIAPSEASANLARYDGVKYGFRASESENLLNMYAKTRSEGFGSEVKRRIMI
CCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHEE
GTYALSAGYYDAYYLKAQKVRTLIKEDFDKAFAKVDILACPTSPTTAFKLGEKSDNPLSM
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCCCCHHHH
YLSDLMTIPVNLAGLPALSLPCGFDQQGLPIGMQLISNVLKEDLLFEAAYVYEQANNWYK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FQPQL
ECCCC
>Mature Secondary Structure 
ASISDIHQQLISKQRSAVEITQEALENINQLEPKLKSFICVTAEKAIAQARQVDAKIAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEHHHHHHHHHHHHHHHHHHC
GEKIGLLTGIPIAVKDNICTRGIPTTCGSKILQNFIPPYESTVTQKLVDAGAIILGKTNL
CCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCC
DEFGMGSSTENSAYQVTTNPWDNTRVPGGSSGGSAAAVASAESVVALGSDTGGSIRQPAS
HHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCHH
FCGVVGIKPTYGLVSRYGLVAYASSMDQIGPLSRTVKDSAILLQAIAGYDPKDSTSLNVP
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
VPDYTKNLTPNLRPKGQIRIGLIQETFGDGLDSSVLQAFTKAVELMQELGAEIQVISCPR
CCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
FSYGLPTYYVIAPSEASANLARYDGVKYGFRASESENLLNMYAKTRSEGFGSEVKRRIMI
CCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHEE
GTYALSAGYYDAYYLKAQKVRTLIKEDFDKAFAKVDILACPTSPTTAFKLGEKSDNPLSM
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEECCCCCCCHHHH
YLSDLMTIPVNLAGLPALSLPCGFDQQGLPIGMQLISNVLKEDLLFEAAYVYEQANNWYK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
FQPQL
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA