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The map label for this gene is tcmP [H]

Identifier: 113475372

GI number: 113475372

Start: 2574511

End: 2575359

Strand: Reverse

Name: tcmP [H]

Synonym: Tery_1692

Alternate gene names: 113475372

Gene position: 2575359-2574511 (Counterclockwise)

Preceding gene: 113475374

Following gene: 113475371

Centisome position: 33.23

GC content: 33.92

Gene sequence:

>849_bases
ATGGCACTATCACAAATTAAATCTATGTTAACAGGTGTACCAGAGACGATGTTGGCAACTTTATACGGTAGAGCAGTAGA
AGCAATGCGTGAAGACGCTATTATTAAAGATGAAAAAGCGATAGAAATTTATAATTCAATTGATTATGATTATGAGGCAA
GTTTTGGAACTCTATGGCGGGCAATGTATACTGGCTTTGCTATTAGGTCAATTATTTTTGATCGAGAAATTAATAAATTT
TTGAGTACATATCCTGATGGCACAATTGTAAATTTAGGAGAAGGCTTAGAAACACACCGTTTCCGAATTGCTAAGGAACA
AGGGTTATGGTTGACGGTCGATGTTCCTGAAGCGATAAAAATCAGGGAGCAGTTCATTAAACCTGATCAAAGACATTTAC
ATATCTCTATGTCAGCATTAGATAGTGGGTGGTTTGATTATGTACCGTTAGATAAACCAGTTTTTATAACTGCCCAAGGT
TTATTTATGTATTTACCTCTAGAAGAGGTTAAGTTAATTATTCAAGATATTGCCAATACATTTAATCAAGGTTATTTAAT
GTTTGATATTGTTCCTCATTGGGTATCACGCAAAACTATGTCAACCCAAGGTTGGAAACTAACTAAAAACTATACAGTTC
CTCAAATGCCTTGGGGACTTAATGGTAACGAAGTACAATCAACCCTTAATAGTTGGTTAACAAATATAGAGGAAATAGTT
GATATTGGTTATGATAACTATCCTCGTGGTGTAATGAAATGGTTATCTTTATTAATATTGTCTTTTACTCCTCTAAAAAA
TATTCTCGCGTCATCGATCGTTAAATTGTCATTCCGAAATCAGAACTAA

Upstream 100 bases:

>100_bases
GACTATAGTGAAGTTCGTCGAAGTTGTCATGCGCTATATATAGTGTCTTTGCGTAAGTCCTGATTTAATAAACACAAAAA
TAGGCAAGTAATAAATAGAA

Downstream 100 bases:

>100_bases
AAAAAATATCTTAAACAAACAACTGATTTTCGGTTCTCTGGTAAGTTGATATTAGAGTTGTTGGGAAATAACTTAGGAGA
GAAAAAACTCAAACGAAAAC

Product: O-methyltransferase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MALSQIKSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWRAMYTGFAIRSIIFDREINKF
LSTYPDGTIVNLGEGLETHRFRIAKEQGLWLTVDVPEAIKIREQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQG
LFMYLPLEEVKLIIQDIANTFNQGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIV
DIGYDNYPRGVMKWLSLLILSFTPLKNILASSIVKLSFRNQN

Sequences:

>Translated_282_residues
MALSQIKSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWRAMYTGFAIRSIIFDREINKF
LSTYPDGTIVNLGEGLETHRFRIAKEQGLWLTVDVPEAIKIREQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQG
LFMYLPLEEVKLIIQDIANTFNQGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIV
DIGYDNYPRGVMKWLSLLILSFTPLKNILASSIVKLSFRNQN
>Mature_281_residues
ALSQIKSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWRAMYTGFAIRSIIFDREINKFL
STYPDGTIVNLGEGLETHRFRIAKEQGLWLTVDVPEAIKIREQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQGL
FMYLPLEEVKLIIQDIANTFNQGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIVD
IGYDNYPRGVMKWLSLLILSFTPLKNILASSIVKLSFRNQN

Specific function: O-methyltransferase that catalyzes the methylation of the C-9 carboxy group of tetracenomycin E (TCM E) to yield TCM A2. Catalyzes as well the following side reactions:methylation of 8- O-methyl-TCM D3 to 9-carboxymethyl-8-O-methyl-TCM D3; and of TCM B3 t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007213
- InterPro:   IPR016874 [H]

Pfam domain/function: PF04072 LCM [H]

EC number: NA

Molecular weight: Translated: 32452; Mature: 32321

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSQIKSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWR
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHH
AMYTGFAIRSIIFDREINKFLSTYPDGTIVNLGEGLETHRFRIAKEQGLWLTVDVPEAIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHEEEEECCCCEEEEECCHHHH
IREQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQGLFMYLPLEEVKLIIQDIANT
HHHHHCCCCCCEEEEEEEHHCCCCCCCCCCCCCEEEEECCEEEEECHHHHHHHHHHHHHH
FNQGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIV
HCCCEEEEEEHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGYDNYPRGVMKWLSLLILSFTPLKNILASSIVKLSFRNQN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
ALSQIKSMLTGVPETMLATLYGRAVEAMREDAIIKDEKAIEIYNSIDYDYEASFGTLWR
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHH
AMYTGFAIRSIIFDREINKFLSTYPDGTIVNLGEGLETHRFRIAKEQGLWLTVDVPEAIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHEEEEECCCCEEEEECCHHHH
IREQFIKPDQRHLHISMSALDSGWFDYVPLDKPVFITAQGLFMYLPLEEVKLIIQDIANT
HHHHHCCCCCCEEEEEEEHHCCCCCCCCCCCCCEEEEECCEEEEECHHHHHHHHHHHHHH
FNQGYLMFDIVPHWVSRKTMSTQGWKLTKNYTVPQMPWGLNGNEVQSTLNSWLTNIEEIV
HCCCEEEEEEHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGYDNYPRGVMKWLSLLILSFTPLKNILASSIVKLSFRNQN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509339 [H]