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The map label for this gene is ndhI

Identifier: 113475270

GI number: 113475270

Start: 2412394

End: 2413023

Strand: Reverse

Name: ndhI

Synonym: Tery_1578

Alternate gene names: 113475270

Gene position: 2413023-2412394 (Counterclockwise)

Preceding gene: 113475271

Following gene: 113475269

Centisome position: 31.14

GC content: 37.3

Gene sequence:

>630_bases
ATGTTCAAATTCCTCAAACAAGTAAGTGATTACGCAAAAGAAACTTTTCAATCAGCGAAATATATTGGTCAAGGTTTATC
TGTAACTTTTGACCACATGAGCCGTCGGCCTGTTACTGTACAGTACCCTTATGAAAAGCTGATTCCTTCTGAAAGATTTC
GAGGTAGAATTCACTTTGAATATGACAAGTGTATTGCTTGTGAAGTTTGTGTAAGGGTTTGTCCAATTAATTTACCTGTA
GTAGATTGGGAATTTAACAAAGAAACCAAAAAGAAAAAGCTTAAGCATTACAGTATTGATTTTGGAGTTTGTATATTCTG
TGGTAACTGTGTAGAATATTGCCCTAGTAACTGTCTATCTATGACAGAAGAGTATGAGTTAGCAGCTTATGATCGCCATG
AGTTAAATTATGATAATGTGGCTCTGGGTAGACTACCATATAAGGTGACAAATGACCCAATGGTTACTCCTATGAGAGAA
CTAGCTTATTTGCCTAAAGGAGTTATTGACCCTCATACAGTTCCTCATACTTCACGTCGTGCTGGTCTGCGCCCTGAAGA
AATTCTGGAACAAATAGAAGCAGAAAAAACAGCCGCAGAAAAAACAGCCGCAGAAATAACAGACAAATAG

Upstream 100 bases:

>100_bases
GTTGTAAAAATTTAATATTAGTAGGATGTTAACTAACAAAATTTATCTCTAACATCAAATAAAGTTTAAATTGTCACTCT
AAGTTTTATAAAGCAAAACC

Downstream 100 bases:

>100_bases
TTATTAGTTATTAGTTATTAGTTTAGAGAGGTTTAAATTGATTTTTAGCCACGACCAACTAATAACTACCAGCTAAAAAA
ATATAATTCAAAGTTTAAGT

Product: NADH dehydrogenase subunit I

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit I; NDH-1 subunit I; NDH-I

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFEYDKCIACEVCVRVCPINLPV
VDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLSMTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRE
LAYLPKGVIDPHTVPHTSRRAGLRPEEILEQIEAEKTAAEKTAAEITDK

Sequences:

>Translated_209_residues
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFEYDKCIACEVCVRVCPINLPV
VDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLSMTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRE
LAYLPKGVIDPHTVPHTSRRAGLRPEEILEQIEAEKTAAEKTAAEITDK
>Mature_209_residues
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFEYDKCIACEVCVRVCPINLPV
VDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLSMTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRE
LAYLPKGVIDPHTVPHTSRRAGLRPEEILEQIEAEKTAAEKTAAEITDK

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=143, Percent_Identity=31.4685314685315, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788617, Length=118, Percent_Identity=32.2033898305085, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789075, Length=136, Percent_Identity=31.6176470588235, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17555194, Length=124, Percent_Identity=31.4516129032258, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864306, Length=140, Percent_Identity=30.7142857142857, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NDHI_TRIEI (Q115G6)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721331.1
- ProteinModelPortal:   Q115G6
- SMR:   Q115G6
- STRING:   Q115G6
- GeneID:   4242727
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1578
- NMPDR:   fig|203124.1.peg.5682
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   HYSIDFG
- PhylomeDB:   Q115G6
- ProtClustDB:   PRK05888
- BioCyc:   TERY203124:TERY_1578-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR004497
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR00403
- TIGRFAMs:   TIGR01971

Pfam domain/function: PF00037 Fer4

EC number: 1.6.5.3

Molecular weight: Translated: 24175; Mature: 24175

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFE
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCEEEECCHHHCCCCHHHCCEEEEE
YDKCIACEVCVRVCPINLPVVDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLS
HHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHCCHHHHH
MTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRELAYLPKGVIDPHTVPHTSRR
HHHHHHHHHCCCCCCCCCCEEECCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
AGLRPEEILEQIEAEKTAAEKTAAEITDK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFE
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCEEEECCHHHCCCCHHHCCEEEEE
YDKCIACEVCVRVCPINLPVVDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLS
HHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHCCHHHHH
MTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRELAYLPKGVIDPHTVPHTSRR
HHHHHHHHHCCCCCCCCCCEEECCCCEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
AGLRPEEILEQIEAEKTAAEKTAAEITDK
CCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA