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The map label for this gene is ndhA

Identifier: 113475271

GI number: 113475271

Start: 2415284

End: 2416402

Strand: Reverse

Name: ndhA

Synonym: Tery_1579

Alternate gene names: 113475271

Gene position: 2416402-2415284 (Counterclockwise)

Preceding gene: 113475272

Following gene: 113475270

Centisome position: 31.18

GC content: 40.04

Gene sequence:

>1119_bases
ATGAATTCAGGAATTGATCTACAAAGAACATTTATTCAAGCCCTTGTAGATTTGGGCTTATCCTCAGAAATAGCTAAAAC
TCTGTGGTTACCATTCCCTATGTTATTAATGATTGTTGTTGCTACTGTTGGCGTTTTAGTAACAGTGTGGCTAGAGCGAA
AAATCTCTGCAGCGGCGCAACAAAGAATTGGCCCTGAATTCATGGGCCCTTTAGGTACTCTCGCACCTCTTGCTGATGGT
TTGAAGCTACTTTTCAAAGAGGACGTTGTTCCGGCCAAAGCAGATCCCTTACTATTCACATTGGGGCCTGTAATTGTAGC
TGTACCCGTGTTTCTTTCCTACTTAGTAGTGCCATTTGGACAAAACTTAGTAATTACAGACCTTGGGGTAGCAATATTTT
TGTGGATTGCTCTTTCGAGCATTCAACCCATTGGACTACTCATGTCTGGCTATGCTTCTAATAATAAATATTCTCTACTT
GGAGGTCTACGAGCAGCAGCACAATCTATCAGTTATGAAATTCCTTTGGCTTTGGCTGTATTGGCAGTAGCGATGATGTC
CAACAGTCTCAGTACAATTGATATTGTTGAACAACAATCAAGCTATGGTATTCTGGGATGGAATATCTGGAGACAACCAC
TAGGGTTCATAATTTTCTGGATAGCGGTCTTGGCTGAATGTGAACGTCTTCCTTTTGATCTTCCAGAAGCAGAAGAAGAA
TTGGTAGCTGGATATCAAACTGAATATACTGGCATGAAATTTGCTCTGTATTACTTAGCCTCCTATGTCAATTTAGTTTT
ATCTTCTCTACTTGTAGCGGTTTTATACCTGGGCGGTTGGGAGTCTCCACTTCCAGTAGAACTTATATCTAATTGGTTTG
GGGTCAGTGAAACAACTCCTTGGTTACAGATAACCAACGCTACTTTGGGTATTATCATGACGTTACTCAAAACTTATTTG
CTTGTATTTATAGCAGTTCTGTTACGTTGGACATTACCAAGGGTAAGAATTGACCAATTATTAGACTTGGGTTGGAAGTT
CTTATTGCCAGTAGCTTTAGTTAATTTGCTATTAACTGCTGCCTTAAAGTTAACCTTTCCATTTGCCTTTGGCGGTTGA

Upstream 100 bases:

>100_bases
CTAATGAACTGTACATCCCTTTGAAGGATCTGCACTGATTACATTAGTAACCCATTTTACTCAAAATTAACTTTCTCTAA
AATAAATAAACAAATTGTAA

Downstream 100 bases:

>100_bases
TATCCTCCTAAGATTGCGCATAAGGAACAACGAGGAATTCCTAAACCTCAAAATCTAGGTTGATTTTTCTCGCGCAACTG
CCTGAAGAAATTTTCTGTAA

Product: NADH dehydrogenase subunit H

Products: NAD+; ubiquinol

Alternate protein names: NAD(P)H dehydrogenase I subunit 1; NDH-1 subunit 1; NDH-A

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQQRIGPEFMGPLGTLAPLADG
LKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFGQNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLL
GGLRAAAQSISYEIPLALAVLAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEE
LVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTPWLQITNATLGIIMTLLKTYL
LVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTAALKLTFPFAFGG

Sequences:

>Translated_372_residues
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQQRIGPEFMGPLGTLAPLADG
LKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFGQNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLL
GGLRAAAQSISYEIPLALAVLAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEE
LVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTPWLQITNATLGIIMTLLKTYL
LVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTAALKLTFPFAFGG
>Mature_372_residues
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQQRIGPEFMGPLGTLAPLADG
LKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFGQNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLL
GGLRAAAQSISYEIPLALAVLAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEE
LVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTPWLQITNATLGIIMTLLKTYL
LVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTAALKLTFPFAFGG

Specific function: NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family

Homologues:

Organism=Homo sapiens, GI251831107, Length=314, Percent_Identity=34.3949044585987, Blast_Score=163, Evalue=3e-40,
Organism=Escherichia coli, GI1788618, Length=331, Percent_Identity=38.368580060423, Blast_Score=234, Evalue=6e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NU1C_TRIEI (Q115G5)

Other databases:

- EMBL:   CP000393
- RefSeq:   YP_721332.1
- STRING:   Q115G5
- GeneID:   4242728
- GenomeReviews:   CP000393_GR
- KEGG:   ter:Tery_1579
- NMPDR:   fig|203124.1.peg.5685
- eggNOG:   COG1005
- HOGENOM:   HBG727670
- OMA:   IFWICAL
- PhylomeDB:   Q115G5
- ProtClustDB:   PRK06076
- BioCyc:   TERY203124:TERY_1579-MONOMER
- HAMAP:   MF_01350
- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086
- PANTHER:   PTHR11432

Pfam domain/function: PF00146 NADHdh

EC number: 1.6.5.3

Molecular weight: Translated: 40780; Mature: 40780

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00667 COMPLEX1_ND1_1; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15bc80e8)-; HASH(0x17178978)-; HASH(0x16de0480)-; HASH(0x16fbcb84)-; HASH(0x17178c6c)-; HASH(0x17178924)-; HASH(0x16b76884)-; HASH(0x16fbce24)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQ
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIGPEFMGPLGTLAPLADGLKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFG
HHCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAV
CCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEE
HHHHHHHCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTP
HHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCC
WLQITNATLGIIMTLLKTYLLVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKLTFPFAFGG
HHHHHCCCCCCH
>Mature Secondary Structure
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQ
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRIGPEFMGPLGTLAPLADGLKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFG
HHCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAV
CCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
LAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEE
HHHHHHHCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTP
HHHCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCC
WLQITNATLGIIMTLLKTYLLVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTA
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKLTFPFAFGG
HHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA